Coagulants
- Name
- Coagulants
- Accession Number
- DBCAT000113
- Description
Agents that cause clotting.
- Drugs
Drug Drug Description Adrenalone Not Annotated Aminaphthone A medication that inhibits erythrocyte aggregation in capillaries, improving venous return for the treatment of capillary fragility. Aminocaproic acid An antifibrinolytic agent used to induce clotting postoperatively. Andexanet alfa A recombinant Factor Xa used to reverse anticoagulation caused by rivaroxaban and apixaban. Anivamersen Anivamersen is under investigation in clinical trial NCT01848106 (A Study to Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI). Anti-inhibitor coagulant complex A medication used to control bleeding episodes and prevent bleeding episodes in hemophilia A and B. Antihemophilic factor human A Factor VIII replacement therapy used to treat hemophilia A. Aprotinin A serine protease inhibitor used to reduce the risk for perioperative blood loss and the need for blood transfusion in high-risk patients during cardiopulmonary bypass for coronary artery bypass graft surgery. Batroxobin No approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously. Beroctocog alfa Beroctocog alfa is indicated for the prevention and control of bleeding in patients with hemophilia A or acquired Factor VIII (FVIII) deficiency. It is also indicated for surgical/invasive procedures in... Bismuth subgallate A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery. Carbazochrome Indicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura. Carbazochrome sulfonic acid A hemostatic agent indicated to treat bleeding in capillary fragility. Desmopressin A synthetic vasopressin (antidiuretic hormone) analog and $V_2$ receptor agonist used as replacement therapy for central diabetes insipidus, and as a prohemostatic agent to increase Factor VIII and von Willebrand factor levels in patients with Hemophilia A or Type 1 von Willebrand disease. Dobesilic acid A medication indicated in the treatment of hemorrhoids, venous insufficiency, and other microangiopathies. Etamsylate A hemostatic agent that acts by restoring capillary resistance and improving platelet adhesion. Ferric subsulfate Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin... Kallidinogenase Not Annotated Lypressin Not Annotated Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Menadione bisulfite Not Annotated Menaquinone Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). Menaquinone 6 Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). Menaquinone 7 Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). Menatetrenone A form of vitamin K2 which is used in the treatment of osteoporosis to stimulate osteogenesis. Naftazone A naphthoquinone derivative indicated in the treatment of varicose veins, hemorrhoids, and superficial thrombophlebitis. Ornipressin Not Annotated Oxidized cellulose Not Annotated Phylloquinone A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. Poliglusam Poliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from... Potassium triiodide Not Annotated Protamine A heparin antagonist indicated in the treatment of heparin overdoses, to counteract heparins preoperatively, or during cardiac surgery and dialysis. Rurioctocog alfa pegol A pegylated recombinant human coagulation factor VIII used to treat and prevent bleeding episodes in patients 12 years and above with hemophilia A. Thrombin A coagulation factor used to stop bleeding during surgery. Tranexamic acid An antifibrinolytic used to reduce or prevent hemorrhagic episodes, especially in the context of hyperfibrinolytic disorders. Vasopressin A peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy. - Drugs & Drug Targets