NCT05031897
Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplant No drug interventions treatment 2 recruiting NCT05853458
Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors treatment 4 recruiting NCT06378437
A Study of GLB-001 in Patients With Myeloid Malignancies No drug interventions treatment 1 recruiting NCT04629508
To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213) treatment 2 completed NCT06351631
A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017) treatment 3 recruiting NCT06506084
Observational Study on the Use of Ropeginterferon Alfa-2b in Polycythemia Vera (ROPEG-PV) Not Available Not Available recruiting NCT05210790
A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera treatment 3 active_not_recruiting NCT04767802
PTG-300 in Patients With Polycythemia Vera and Elevated Hematocrit treatment 2 completed NCT02912884
Treatment of Polycythaemia Vera and Essential Thrombocythaemia: Influence on the Clot Structure No drug interventions Not Available Not Available completed NCT05481151
A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV treatment 3 recruiting NCT00890747
Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy treatment 1 completed NCT00715247
Polycythemia Vera, Myelofibrosis and Essential Thrombocythemia: Identification of PV, MF & ET Genes No drug interventions Not Available Not Available completed NCT02897297
Myeloproliferative Neoplastic Diseases Observatory From Brest No drug interventions Not Available Not Available recruiting NCT01998828
Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia treatment 2 terminated NCT06218628
Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition treatment 1 recruiting NCT04644211
Ruxolitinib in Thrombocythemia and Polycythemia Vera treatment 2 recruiting NCT03745378
Secondary Cancers in Myeloproliferative Neoplasms (MPN-K Study) No drug interventions Not Available Not Available completed NCT04051307
Dual Vaccine Trial in Myeloproliferative Neoplasms No drug interventions treatment 1 / 2 completed NCT01038856
Trial of Erlotinib in Patients With JAK-2 V617F Positive Polycythemia Vera treatment 2 terminated NCT00025415
Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction treatment 1 completed NCT01901432
A Two-part Study to Assess the Safety and Preliminary Efficacy of Givinostat in Patients With Polycythemia Vera treatment 1 / 2 completed NCT01787552
A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF treatment 1 / 2 completed NCT00946270
Pomalidomide for Myelofibrosis Patients treatment 2 completed NCT00509899
Open Label Ruxolitinib (INCB018424) in Patients With Myelofibrosis and Post Polycythemia Vera/Essential Thrombocythemia Myelofibrosis treatment 1 / 2 completed NCT03878199
Testing the Effect of Taking Ruxolitinib and CPX-351 in Combination for the Treatment of Advanced Phase Myeloproliferative Neoplasms treatment 1 / 2 recruiting NCT00666549
Research Tissue Bank No drug interventions Not Available Not Available completed NCT03907436
The NUTRIENT Trial (NUTRitional Intervention Among myEloproliferative Neoplasms): Feasibility Phase No drug interventions treatment Not Available completed NCT02038036
Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy. treatment 3 completed NCT05499013
Study to Assess SLN124 in Patients With Polycythemia Vera treatment 1 / 2 recruiting NCT01384513
A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies treatment 2 completed NCT00397813
Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders treatment 2 completed NCT00241241
Efficacy and Safety of Pegylated Interferon Alfa in Polycythemia Vera treatment 2 completed NCT05558696
A Study of Bomedemstat (MK-3543) in Participants With Polycythemia Vera (MK-3543-004) treatment 2 active_not_recruiting NCT06063486
Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms No drug interventions treatment 2 recruiting NCT03333486
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer treatment 2 active_not_recruiting NCT03003325
The Benefit/Risk Profile of AOP2014 in Low-risk Patients With PV treatment 2 completed NCT02493530
TGR-1202 + Ruxolitinib PMF PPV-MF PET-MF MDS/MPN Polycythemia Vera Resistant to Hydroxyurea treatment 1 completed NCT03862157
Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia treatment 1 / 2 active_not_recruiting NCT00430066
Effects of Imatinib Mesylate in Polycythemia Vera treatment 2 completed NCT05123365
An Optimal Dose Finding Study of N-Acetylcysteine in Patients With Myeloproliferative Neoplasms treatment 1 / 2 recruiting NCT06290765
Efficacy and Safety of Ropeginterferon Alfa 2b (P1101) for Patients With Low-Risk Polycythemia Vera treatment 4 not_yet_recruiting NCT00522574
A Safety Study of XL019 in Adults With Myelofibrosis treatment 1 terminated NCT01134120
A Study in Myeloproliferative Disorders treatment 1 completed NCT01520220
Study of LY2784544 Testing Alternative Dosing in Participants With Myeloproliferative Neoplasms treatment 1 completed NCT02556931
Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies treatment 2 completed NCT05882773
Asian Myeloproliferative Neoplasm (MPN) Registry No drug interventions Not Available Not Available recruiting NCT06371573
Ultrasound Examination for Spleen Volume Evaluation in Myeloproliferative Neoplasms No drug interventions Not Available Not Available completed NCT01529827
Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies treatment 2 completed NCT05198960
AVAJAK: Apixaban/Rivaroxaban Versus Aspirin for Primary Prevention of Thrombo-embolic Complications in JAK2V617F-positive Myeloproliferative Neoplasms prevention 3 recruiting NCT00588991
Veliparib and Topotecan With or Without Carboplatin in Treating Patients With Relapsed or Refractory Acute Leukemia, High-Risk Myelodysplasia, or Aggressive Myeloproliferative Disorders treatment 1 active_not_recruiting NCT00227591
Lenalidomide and Prednisone in Treating Patients With Myelofibrosis treatment 2 completed NCT01199562
Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant Not Available Not Available completed NCT00866762
A Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia treatment 2 unknown_status NCT00433862
Molecular Changes and Biomarkers in Chronic Myeloproliferative Disorders No drug interventions Not Available Not Available completed NCT00445744
Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome treatment Not Available completed NCT04057040
Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE) treatment 2 active_not_recruiting NCT06093672
Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera treatment 3 recruiting NCT02805868
Siltuximab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis treatment 0 withdrawn NCT02292446
Expanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resistant or Intolerant and for Whom no Treatment Alternatives Was Available. treatment 3 completed NCT04896112
A Study of LNK01002 in Patients With Primary or Secondary Myelofibrosis,Polycythemia Vera or Acute Myeloid Leukemia No drug interventions treatment 1 withdrawn NCT03289910
Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia treatment 2 active_not_recruiting NCT00745550
A Phase 1/2 Study of Oral SB1518 in Subjects With Chronic Idiopathic Myelofibrosis treatment 1 / 2 completed NCT02760238
Myeloproliferative Neoplasms (MPNs) Patient Registry No drug interventions Not Available Not Available recruiting NCT00047190
Tipifarnib in Treating Patients With Myelofibrosis and Myeloid Metaplasia treatment 2 completed NCT00668421
CEP-701 (Lestaurtinib) in Myelofibrosis treatment 1 / 2 unknown_status NCT01120821
Treatment of Polycythemia Vera With Gleevec treatment 2 completed NCT06251102
Real-world Ruxolitinib Experience in PV No drug interventions Not Available Not Available not_yet_recruiting NCT06134102
Clinical and Laboratory Characteristics of Polycythemia Vera No drug interventions Not Available Not Available completed NCT04116502
MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera treatment 3 recruiting NCT02823184
Endoplasmic Reticulum Stress and Resistance to Treatments in Ph-negative Myeloproliferative Neoplasms No drug interventions Not Available Not Available completed NCT00940784
Clopidogrel and Aspirin for the Treatment of Polycythemia Vera treatment 2 withdrawn NCT04282187
Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasms treatment 2 recruiting NCT00586651
Open-Label Study of Oral CEP-701 (Lestaurtinib) in Patients With Polycythemia Vera or Essential Thrombocytosis treatment 2 completed NCT02218047
AOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study. other 3 completed NCT01499147
Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies treatment Not Available completed NCT05853445
A Prospective, Non-interventional Study of JAKAVI® (Ruxolitinib) Treatment in Patients With Polycythemia Vera No drug interventions Not Available Not Available completed NCT03287245
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Idasanutlin Monotherapy in Participants With Hydroxyurea-Resistant/Intolerant Polycythemia Vera treatment 2 terminated NCT00357305
Vorinostat, Cytarabine, and Etoposide in Treating Patients With Relapsed and/or Refractory Acute Leukemia or Myelodysplastic Syndromes or Myeloproliferative Disorders treatment 1 completed NCT01949805
Pegylated Interferon Alpha-2b Versus Hydroxyurea in Polycythemia Vera treatment 3 completed NCT00089011
Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer treatment 2 completed NCT00112593
Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer treatment Not Available completed NCT05269771
MAP to Provide Access to Ruxolitinib, for Patients With Polycythemia Vera Not Available Not Available available NCT00928707
Phase II Study of GIVINOSTAT (ITF2357) in Combination With Hydroxyurea in Polycythemia Vera treatment 2 completed NCT01588015
Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant No drug interventions supportive_care 1 completed NCT03065400
PD-1 Inhibition in Advanced Myeloproliferative Neoplasms treatment 2 completed NCT02386800
CINC424A2X01B Rollover Protocol treatment 4 recruiting NCT00038675
Therapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and Mastocytosis With Imatinib Mesylate treatment Not Available completed NCT05870475
Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV treatment 2 recruiting NCT03121599
18F-FLT (PET/CT) in Pediatrics With Myeloproliferative Neoplasms No drug interventions diagnostic Not Available terminated NCT01193699
Safety Study of Pegylated Interferon Alpha 2b to Treat Polycythemia Vera treatment 1 / 2 completed NCT06361641
Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes No drug interventions diagnostic Not Available recruiting NCT04262141
IMG-7289 in Patients With Essential Thrombocythemia (ET) or Polycythemia Vera (PV) treatment 2 active_not_recruiting NCT01645124
Large-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV) treatment 3 terminated NCT00039416
Imatinib Mesylate in Treating Patients With Myelofibrosis treatment 2 completed NCT01831635
Myeloproliferative Neoplasms: an In-depth Case-control Study No drug interventions Not Available Not Available completed NCT05566535
Changes in QoL and Symptoms in Patients With Polycythemia Vera Receiving Ruxo in a Routine Clinical Practice Not Available Not Available unknown_status NCT01387763
A Study of Low Dose Interferon Alpha Versus Hydroxyurea in Treatment of Chronic Myeloid Neoplasms treatment 3 completed NCT04821063
Placebo-Corrected Effects of Therapeutic Dose (100 mg) and Supratherapeutic Dose (300 mg) of ITF2357 (Givinostat) and Moxifloxacin on QT/QTC Interval treatment 1 completed NCT06033586
Study to Evaluate the Long-term Safety of Rusfertide (PTG-300) in Subjects With Polycythemia Vera treatment 3 enrolling_by_invitation NCT01816022
Myeloproliferative Neoplasms and Bone Structure No drug interventions Not Available Not Available unknown_status NCT01970930
Tissue Banking Study - Polycythemia Vera or Essential Thrombocythemia (PV & ET) Patients No drug interventions Not Available Not Available completed NCT05485948
A Study to Access Efficacy and Safety of P1101 in Chinese PV Patients Who Are Intolerant or Resistance to HU treatment 2 active_not_recruiting NCT02663648
Cell Cycle Regulatory Gene Study in Patients With Myeloproliferative Disorders No drug interventions Not Available Not Available withdrawn NCT05993065
Hematocrit to Hemoglobin Ratio and Red Blood Cell Distribution Width in Polycythemia Vera and Secondary Erythrocytosis. No drug interventions Not Available Not Available recruiting NCT03669965
KRT-232 Compared to Ruxolitinib in Patients With Phlebotomy-Dependent Polycythemia Vera treatment 2 unknown_status NCT02809274
Incidence of Iron Deficiency in Polycythemia Vera (PV) and Association With Disease Features No drug interventions Not Available Not Available unknown_status NCT00052520
Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation treatment 1 / 2 completed NCT01243073
Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera treatment 2 completed NCT01053494
Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer No drug interventions supportive_care Not Available completed NCT05548062
Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera No drug interventions Not Available Not Available active_not_recruiting NCT02407080
Open Label Study of Single Agent Oral RG7388 in Patients With Polycythemia Vera and Essential Thrombocythemia treatment 1 completed NCT00538980
Dasatinib in Polycythemia Vera treatment 2 terminated NCT00595829
A Phase 1 Study of XL019 in Adults With Polycythemia Vera treatment 1 terminated NCT00666289
Familial Myeloproliferative Disorders No drug interventions Not Available Not Available completed NCT01243944
Study of Efficacy and Safety in Polycythemia Vera Subjects Who Are Resistant to or Intolerant of Hydroxyurea: JAK Inhibitor INC424 (INCB018424) Tablets Versus Best Available Care: (The RESPONSE Trial) treatment 3 completed NCT00665067
Correlative Biomarker Study in Patients With Myeloproliferative Disorders No drug interventions Not Available Not Available completed NCT02129101
Azacitidine and Sonidegib or Decitabine in Treating Patients With Myeloid Malignancies treatment 1 completed NCT01632904
Randomized Switch Study From Hydroxyurea to Ruxolitinib for RELIEF of Polycythemia Vera Symptoms: The Relief Study treatment 3 completed NCT02311569
Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation treatment 2 completed NCT00255346
Dasatinib as Therapy for Myeloproliferative Disorders (MPDs) treatment 2 completed NCT01014546
Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis treatment 1 terminated NCT02124746
Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia treatment 2 completed NCT01284712
Natural Killer Cells and Polycythemia Vera (Vaquez's Disease) No drug interventions Not Available Not Available unknown_status NCT02893410
Drug Observance and Side Effects of Cytoreductive Drugs in PV and ET Patients No drug interventions Not Available Not Available completed NCT01760655
Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies treatment 2 completed NCT05074550
Safety Evaluation Study for Patients With Polycythemia Vera No drug interventions treatment 1 recruiting NCT00381550
3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia treatment 2 completed NCT01981850
A Phase 2 Study of RO7490677 In Participants With Myelofibrosis treatment 2 completed NCT02523638
Study to Assess the Self-administration of AOP2014 Using a Pen, Developed for the Treatment of Polycythemia Vera Patients treatment 3 completed NCT03972943
CPAP in Treating Obstructive Sleep Apnea in Patients With Polycythemia Vera or Essential Thrombocythemia No drug interventions treatment 0 terminated NCT04821791
To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy. (LIMBER-213) treatment 2 recruiting NCT04745637
Managed Access Programs for INC424, Ruxolitinib Not Available Not Available available NCT06002490
A Study to Evaluate P1101 in Japanese PV Patients treatment 3 recruiting NCT04655092
Extension Study of P1101 After Completion of Phase 2 Study in PV Patients or Phase 3 Study in ET Patients treatment 3 recruiting NCT05421104
Ruxolitinib for Polycythemia Vera in Patients Resistant to or Intolerant of Hydroxyurea. No drug interventions Not Available Not Available completed NCT01816256
Screening for Asymptomatic Portal Vein Thrombosis and Portal Hypertension in Patients With Philadelphia Negative Myeloproliferative Neoplasms No drug interventions screening Not Available completed NCT04182100
Efficacy and Safety of P1101 in Polycythemia Vera Patients for Whom the Standard of Treatment is Difficult to Apply treatment 2 completed NCT06541249
MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial treatment 2 not_yet_recruiting NCT04243122
Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients prevention 2 completed NCT02577926
The Ruxo-BEAT Trial in Patients With High-risk Polycythemia Vera or High-risk Essential Thrombocythemia treatment 2 active_not_recruiting