Acute Leukemia (DBCOND0030152)

Identifiers

Synonyms
Acute-Leukemia / Acute Leukaemia / Acute Leukemias / Leukaemia, Acute / Leukaemia (Acute) / Leukemia, Acute / Leukemia acute / Acute Leukemia (Category) / Acute leukemia / Acute leukemia of unspecified cell type not having achieved remission / Acute leukemia of unspecified cell type / Leukemia of unspecified cell type, acute / Acute leukaemia of unspecified cell type / Acute leukemia NOS / Leukaemia of unspecified cell type, acute / Leukaemia acute / Acute leukemia (morphologic abnormality) / Acute leukemia, disease (disorder) / Acute leukaemia NOS / Leukaemia stem cell / Leukemia stem cell / Leukemia undifferentiated / Leukaemia undifferentiated

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cortisone acetate
A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Hydrocortisone
A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Methylprednisolone
A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Prednisone
A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06585345
Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell in Patients With Relapsed/Refractory Acute LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT02058888
Amplification and Selection of Antimicrobial Resistance in the IntestineNo drug interventionsNot AvailableNot Availablecompleted
NCT00795132
Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignanciestreatment2completed
NCT00570999
Palifermin After Haploidentical PBSCTtreatment2withdrawn
NCT02123836
Natural Killer Cells in Acute Leukaemia and Myelodysplastic Syndrometreatment1unknown_status
NCT00993538
Leukemia Cell Cultures for Research of New Anti-Cancer TherapiesNo drug interventionsbasic_scienceNot Availableunknown_status
NCT01521611
Targeted Radiotherapy in HSCT for Poor Risk Haematological MalignancyNo drug interventionstreatment1 / 2completed
NCT01890746
A Safety and Efficacy Study of Eltrombopag in Subjects With AMLNo drug interventionstreatment2completed
NCT05521087
A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemiastreatment1withdrawn
NCT02141828
A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Genetreatment1completed
NCT02145039
Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic DiseasestreatmentNot Availableterminated
NCT01479582
Providing Access to Cord Blood Units for TransplantsNo drug interventionstreatment2withdrawn
NCT01826214
Study of Efficacy and Safety of LDE225 in Adult Patients With Relapsed/Refractory Acute Leukemiatreatment2completed
NCT01339988
Busulfan and Cyclophosphamide Instead of Total Boby Irradiation (TBI) and Cyclophosphamide for Hematological Malignancies Hematocrit (HCT)treatment4unknown_status
NCT01919866
Safety Study of CD3/CD19 Depleted Haploidentical Stem CellsNo drug interventionstreatment1 / 2unknown_status
NCT04811560
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemiatreatment1 / 2recruiting
NCT01334060
WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular ElectroporationNo drug interventionstreatment2completed
NCT03680677
Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic MalignanciesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05823571
Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patientstreatment1recruiting
NCT03336632
Chidamide Plus PTCy/Cyclosporine to Prevent GVHD After Myeloablative Conditioning, Matched PBSCTtreatment2unknown_status
NCT05969600
The Relapses in Childhood Acute Lymphoplastic Leukemia Excluding L3No drug interventionsNot AvailableNot Availablecompleted
NCT04745416
Clinical Characteristics of Patients With Leukemia and COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT05236296
Emotion and Symptom-focused Engagement for Caregivers (EASE-CG) Pilot StudyNo drug interventionssupportive_careNot Availablerecruiting
NCT04236063
Rehabilitation Needs of the Malaysian Haematological Cancer SurvivorsNo drug interventionsNot AvailableNot Availablecompleted
NCT04194086
Population Pharmacokinetics and Safety of Oral Posaconazole in Children With Leukemiatreatment1 / 2completed
NCT03297476
Clinical Application of Novel Panels for Early Precision Diagnosis and Relapse Prediction in High-risk LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03553238
Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALLtreatment2 / 3unknown_status
NCT01050764
Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cellstreatment1 / 2terminated
NCT06335277
Total Body Irradiation Treatments for Patients Treated at European Institute of OncologyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03564470
Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALLtreatment2 / 3unknown_status
NCT03963024
Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCTtreatment1terminated
NCT04051216
The SMART CART Study: Health Information TechnologyNo drug interventionssupportive_careNot Availablecompleted
NCT04482894
Palliative Care Oncology in Patients With Relapsed, Refractory, and High-Risk Leukemias or MDSNo drug interventionssupportive_care2recruiting
NCT03434704
Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazoletreatment2completed
NCT03564704
Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALLtreatment2 / 3unknown_status
NCT04710212
Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic MalignanciesNo drug interventionsNot AvailableNot Availablecompleted
NCT01800643
Evaluation of Plasmatic Levels of Busulfan in Patients Undergoing Hematopoietic Stem Cell TransplantationNo drug interventionstreatment2 / 3unknown_status
NCT01603290
Change of Fatigue and Physical Fitness in Hospitalized Hematology PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02677064
Identify Barriers to Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Newly Diagnosed and Relapsed Acute LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03469921
Unicentric Retrospective Analysis of a Cohort of 602 Young Adult and Adolescent Patients (AJA), Aged 15 to 30 Years, With Haematological Malignancies, and Managed Between 2000 and 2016No drug interventionsNot AvailableNot Availablecompleted
NCT01728402
Pathogenesis of Hematologic MalignanciesNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT06265584
Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell TransplantNo drug interventionstreatment2not_yet_recruiting
NCT02752243
CIK-Cells in Relapsing Patients With Acute Leukemia or Myelodysplastic Syndromes After SCT.No drug interventionstreatment1 / 2unknown_status
NCT04195633
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignanciestreatment2recruiting
NCT03672851
Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute LeukemiaNo drug interventionstreatment1terminated
NCT03176277
A Study of ONO-7475 in Patients With Acute Leukemiastreatment1 / 2terminated
NCT03735797
Cancer Stem Cells in Acute LeukemiaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04331483
A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell AllograftsNo drug interventionssupportive_careNot Availablewithdrawn
NCT01814488
A Phase II Study on Allogeneic Stem Cell Transplantation in Patients With Active Acute LeukemiaNo drug interventionstreatment2completed
NCT03959007
Impact of Supportive Care on the Experience of Hospitalization of Patients Staying in the Protected Area of the Department of Blood DiseasesNo drug interventionssupportive_careNot Availablerecruiting
NCT03412409
RIC Regimen for Elderly or High Comorbidity Burden Patients Receiving Haplo-HSCTtreatment2recruiting
NCT06315309
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplanttreatment2not_yet_recruiting
NCT00852709
Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemiastreatment1terminated
NCT01900509
Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic Malignanciestreatment1completed
NCT02930109
A Study of PTX-200 (Triciribine) Plus Cytarabine in Refractory or Relapsed Acute Leukemiatreatment1 / 2completed
NCT03316456
Gut Microbiota in Intestinal Barrier Damage in Acute Leukemia Patients Undergoing Inpatient InductionNo drug interventionsNot AvailableNot Availablecompleted
NCT05088356
Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Grafttreatment1recruiting
NCT03698656
Effect on Patient Quality of Life of Taking Into Account the Spiritual Dimension in Nurse's Care for Haematologic Cancers.No drug interventionsNot AvailableNot Availablecompleted
NCT02320656
Predictive Clinical and Biological Parameters in Acute Leukemia, Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015No drug interventionsbasic_scienceNot Availableunknown_status
NCT05634915
Clinical Study of rATG Individualized Administration in Haploidentical Hematopoietic Stem Cell TransplantationNo drug interventionstreatment4recruiting
NCT05035615
Evaluation of the BD OneFlow Acute Leukemia Panel on the BD FACSLyric Flow CytometerNo drug interventionsNot AvailableNot Availablecompleted
NCT02823132
Study of the Level of a Protein Which Could Predict the Development of a Fungal Infection in Patients With Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04767152
Evaluation of Brain Changes in ALL Patients on TherapyNo drug interventionsdiagnosticNot Availablerecruiting
NCT03279900
Hematotoxicity in Acute Lymphoblastic Leukemia Children in Maintenance Phase TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT02353559
Emotion And Symptom-focused Engagement (EASE): An Intervention for Individuals With Acute LeukemiaNo drug interventionstreatmentNot Availablecompleted
NCT02356159
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantationtreatment1 / 2active_not_recruiting
NCT03756675
Haploidentical Peripheral Blood Stem Cell Transplantation for Acute LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05120570
PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC TransplantationNo drug interventionssupportive_care1 / 2recruiting
NCT04281199
TBI Using IMRT (VMAT or Tomotherapy) for the Prevention of Pul Toxicities in Patients Undergoing Donor SCTNo drug interventionstreatment1active_not_recruiting
NCT02693899
Prospective Study on the Feasibility of Plasma FLT3-Ligand Assay to Achieve a First Estimate of Its Prognostic Value on the Outcome of Patients Treated Intensively for Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01314599
Clinical Study of PM01183 in Patients With Acute Leukemia or Relapsed/Refractory Myelodysplastic SyndromeNot Available1completed
NCT02730299
Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDStreatment3active_not_recruiting
NCT03016806
Umbilical Cord Blood Transplantation From Unrelated Donorstreatment1recruiting
NCT03493906
Patient Ambassador Support in Newly Diagnosed Patients With Acute Leukemia During TreatmentNo drug interventionssupportive_careNot Availablecompleted
NCT03588936
Nivolumab and Tocilizumab for Relapsed Hematological Malignancy Post-allogeneic Transplanttreatment1terminated
NCT00988013
Intensity Modulated Total Marrow Irradiation (IM-TMI) for Advanced Hematologic MalignanciesNo drug interventionstreatmentNot Availablecompleted
NCT05406817
Study of Radiolabeled Revumenib in Adults With Acute Leukemiatreatment1recruiting
NCT03178617
High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic LymphomaNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT05902416
Clinical Registration Study of Haplo-HSCT for Elderly Patients With Acute Leukemia/ Myelodysplastic SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT01498016
Pharmacokinetic Study of Busulfan in Allogeneic Stem Cell Transplantation in Adult Patients With Acute Leukemiatreatment2unknown_status
NCT00823316
Safety and Efficacy Study of Umbilical Cord Blood-Drived Mesenchymal Stem Cells to Promote Engraftment of Unrelated Hematopoietic Stem Cell TransplantationNo drug interventionstreatment1 / 2completed
NCT05589896
A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic MalignanciesNo drug interventionstreatment1 / 2recruiting
NCT03970096
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)treatment2recruiting
NCT01709396
ED-TBI Followed By Allogeneic Stem Cell Transplantation For The Treatment Of Refractory AML And Advanced MDSNo drug interventionstreatment2suspended
NCT00048958
Cytogenetic Studies in Acute Leukemia and Multiple MyelomaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05328258
Use of GnRHa During Chemotherapy for Fertility Protectiontreatment3recruiting
NCT06058858
Incidence and Risks Factors of CMV Reactivation in Patients Receiving of CAR-T Cells for Acute Leukemia and Lymphoma Relapse, a Cohort Study AnalysisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04202835
ATG Plus PTCy vs ATG for CGVHD Prophylaxisprevention2recruiting
NCT06026839
Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing FactorsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01598025
Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible DonortreatmentNot Availableterminated
NCT03434730
Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantationtreatment2active_not_recruiting
NCT05298930
Feasibility Study to Assess an Adapted Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell TransplantationNo drug interventionssupportive_careNot Availablecompleted
NCT00520130
Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune Systemtreatment1 / 2completed
NCT05335226
Combined Haploidentical and Umbilical Cord Blood Allogeneic Stem Cell Transplantation in Patients With Acute LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT02344966
Cohort Study of New Prognostic Factors With Peripheral Blood and Bone Marrow Evaluation at the Time of Diagnosis and During Treatment or Thereafter in Acute LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04767165
Quantitative MRI of Bone Marrow in Patients With Acute Lymphoblastic LeukemiaNo drug interventionsdiagnosticNot Availablerecruiting
NCT04224974
Emotion and Symptom-Focused Engagement Trial for Individuals With Acute LeukemiaNo drug interventionssupportive_careNot Availablerecruiting
NCT03314974
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme DisordersNo drug interventionstreatment2recruiting
NCT05071482
Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALLtreatment4recruiting
NCT03969082
Evaluation of Bibliotherapy by Students and Patients With CancerNo drug interventionssupportive_careNot Availablecompleted
NCT04899882
Physical Fitness Impact of Early Physiotherapy Intervention With a Standardized Exercise Therapy Program in Adult Patients Receiving Intensive Induction Chemotherapy for Treatment of Acute Leukemia During Extended Hospitalization.No drug interventionstreatmentNot Availablerecruiting
NCT04084327
Immunophenotyping of Acute b Cell Lymphoblstic LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05428176
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer SurvivorsNo drug interventionssupportive_careNot Availablerecruiting
NCT03042676
Electronic Database for the Follow up of the ATG_FamilyStudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06279494
Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitorsprevention1 / 2not_yet_recruiting
NCT02169791
Nonmyeloablative Haploidentical Transplant Followed by MLN9708prevention2completed
NCT02451592
Fungemia in Hematologic MalignanciesNo drug interventionsNot AvailableNot Availablecompleted
NCT00701844
Sharing Our Strength: A Research Study for Bone Marrow/Stem Cell Transplant SurvivorsNo drug interventionstreatmentNot Availablecompleted
NCT05316701
Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment3active_not_recruiting
NCT04339101
Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantationtreatment2active_not_recruiting
NCT01502072
Respiratory Syncytial Virus - RSV Protocoltreatment2completed
NCT06058572
Effect of Rifaximin on Gut Bacterial Flora Post Stem Cell Transplant in Patients With Acute Leukemiatreatment2not_yet_recruiting
NCT03669172
Efectiveness of Donor IL-15-stimulated NK Cells Post Transplant Infusion in in Acute Leukemiatreatment1 / 2completed
NCT01321372
An Observational Analysis of Voriconazole Therapeutic Drug Concentration Monitoring, Pharmacogenomics and Clinical Outcome Correlations in High-risk Hematology PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02722668
UCB Transplant for Hematological Diseases Using a Non Myeloablative Preptreatment2active_not_recruiting
NCT00592046
A Phase I Trial of ZIO-101 in Hematologic Cancerstreatment1completed
NCT05974410
Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer PatientsNot AvailableNot Availableavailable
NCT03408210
Total Marrow and Lymphoid Irradiation and Chemotherapy for Myelodysplastic Syndrome or Acute LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT03138395
iCare3: Monitoring Circulating Cancer DNA After Chemotherapy in MDS and AMLNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04328714
Interferon γ-Primed Mesenchymal Stromal Cells as Prophylaxis for Acute Graft v Host Diseasetreatment1suspended
NCT02345850
Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301)prevention3completed
NCT05809050
Study of miRNA-155 in Acute LeukemiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06207123
A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)treatment1 / 2not_yet_recruiting
NCT00899223
Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic SyndromesNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03408223
Total Marrow and Lymphoid Irradiation and Chemotherapy for High-Risk Acute LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT03298321
Action of the Vidaza on the Atrial FibrillationNo drug interventionsNot AvailableNot Availableunknown_status
NCT04298502
The Molecular Mechanism of CMV-driven NKG2C+NK Cell Expansion in HumanNo drug interventionsNot AvailableNot Availableunknown_status
NCT04409379
Association Between Telomere Length and Cardiac DysfunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT03779854
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplanttreatment2recruiting
NCT02344953
Prospective and Retrospective Cohort Study of New Prognostic Factors With Peripheral Blood and Bone Marrow Evaluation at the Time of Diagnosis and During Treatment or Thereafter in Acute Leukemia (Acute Leukemia HSCT Cohort)No drug interventionsNot AvailableNot Availableunknown_status
NCT01496547
Sequential Intensive Chemotherapy Followed by RIC for Refractory and Relapse AMLNo drug interventionstreatment2completed
NCT01499147
Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic MalignanciestreatmentNot Availablecompleted
NCT04674345
Sorafenib Maintenance for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3 Negative Acute Leukemiatreatment2 / 3unknown_status
NCT03278145
Dependence Receptors and LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01855698
PENELOPE Observational Study: Prophylaxis and Treatment of Arterial and Venous ThromboembolismNo drug interventionsNot AvailableNot Availablecompleted
NCT04187105
BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)treatment2recruiting
NCT02038361
Implementation of Innovative Techniques in Routine Diagnosis of Childhood Acute Leukemia: Analysis of Genome and Transcriptome by Micro-arrayNo drug interventionsdiagnosticNot Availablecompleted
NCT05170828
Cryopreserved MMUD BM With PTCy for Hematologic Malignanciestreatment1withdrawn
NCT03297528
Chemotherapy and DLI for Prevention of Second Relapse in Patients With Relapsed Acute Leukemia After AllotransplantNo drug interventionsprevention2unknown_status
NCT04904211
Feasiblity and Safety of Home-based Intensive ChemotherapyNo drug interventionssupportive_careNot Availablecompleted
NCT02580071
Chinese Herbal Medicine for Immune Reconstitution Following HSCT in Acute Leukemia PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT02440178
Micafungin Prophylaxis During 1st Induction Chemotherapy for De Novo Acute Leukemiaprevention2completed
NCT02445378
Aromatherapy and Essential Oils in Improving Insomnia and Other Symptoms in Patients With Newly Diagnosed Acute Leukemia Undergoing ChemotherapyNo drug interventionssupportive_careNot Availablecompleted
NCT05587088
Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)No drug interventionstreatment1 / 2not_yet_recruiting
NCT04904588
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamidetreatment2recruiting
NCT06001788
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT01660607
Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T CellNo drug interventionstreatment1 / 2completed
NCT02246907
Exercise and Quality of Life in Leukemia PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT01036009
A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic MalignanciesNo drug interventionstreatment2completed
NCT05320809
Study of 3D189 in Patients With Hematologic Malignanciestreatment1active_not_recruiting
NCT03743909
Expression of Aberrant CD Markers in Acute Leukemia:Retrospective Study in South Egypt Cancer InstituteNo drug interventionsNot AvailableNot Availableunknown_status
NCT03792256
Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)treatment1active_not_recruiting
NCT01362985
Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of PlerixaforNo drug interventionsNot AvailableNot Availablecompleted
NCT01239485
Study of IRNEA (Irinotecan, Etoposide, Cytarabine) for Refractory or Relapsed Acute Leukemia in Children and Adolescentstreatment1unknown_status
NCT04013685
Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment1active_not_recruiting
NCT03267485
Expression of TET1 Gene in Acute LeukaemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT06001385
HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxistreatment2recruiting
NCT02208037
Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)prevention2completed
NCT05053100
Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04451200
Sequential and Personalized PK-guided Busulfan Administration in the Frame of the Conditiong Regimen for Allo-HSCT in Patients With Malignant Hemopathies Ineligible for the Standard Myeloablative Conditioningtreatment2not_yet_recruiting
NCT03595800
Extension of a Study of Allogeneic Hematopoietic Stem Cell Transplantation From One Haplotype Mismatch Related Donor or From an Unrelated Donor to Younger Patients Eligible for Reduced-intensity Conditioning RegimenNo drug interventionstreatment3unknown_status
NCT01509300
HLA-haploidentical Hematopoietic Stem Cell Transplantation for Children and Adolescents With Acute Leukemia, Myelodysplastic Syndrome and Solid Tumorstreatment1 / 2unknown_status
NCT03128359
High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplantsupportive_care2completed
NCT01020175
Peripheral Blood (PB) Versus Bone Marrow (BM) in Allogeneic Stem Cell TransplantationNo drug interventionstreatment3completed
NCT01615042
Phase I Study of Lenalidomide in Patients With Acute Leukemiatreatment1terminated
NCT03739606
Flotetuzumab in Treating Patients With Recurrent or Refractory CD123 Positive Blood CancerNo drug interventionstreatment2withdrawn
NCT04151706
CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CMLtreatment2completed
NCT00273936
Trial of AVN-944 in Patients With Advanced Hematologic MalignanciesNot Available1completed
NCT01661413
Nausea and Vomiting in Children Receiving Chemotherapeautic MonotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT03232619
CD19-CART Treatment for ALLNo drug interventionstreatment1 / 2completed
NCT03959241
TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)prevention3completed
NCT05735717
MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignanciestreatment2recruiting
NCT06575296
Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplanttreatment1not_yet_recruiting
NCT03810196
CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCTNo drug interventionstreatmentNot Availablerecruiting
NCT01350258
Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Stepstreatment1 / 2terminated
NCT04551235
Establishing Automatic Method of Counting and Classify Bone Marrow and Peripheral Blood CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01557686
Health Counseling and Exercise in Patients With Acute Leukemia - Pilot StudyNo drug interventionssupportive_care0completed
NCT04597086
Bright White Light Therapy for the Improvement of Sleep, Fatigue, Distress, Depression, and Anxiety in Hospitalized Leukemia PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT06356922
Study Assessing RLT Using [177Lu]Lu-PentixaTher for Relapsed/Refractory CXCR4+ Acute Leukemia.treatment1 / 2not_yet_recruiting
NCT05739630
M-PTCy vs BuCy in Haploidentical HSCT for Acute Leukemiatreatment2 / 3recruiting
NCT01956630
Clinical Study of DC Plus CIK for Patients With Relapse Acute Leukemia After Allo-HSCTNo drug interventionstreatment1 / 2unknown_status
NCT03364257
iDTECT Blood Performance for the Identification of Viral or Bacterial Pathogens in Febrile Neutropenic PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02822326
Phase I Study of CD19-CAR-T2 Cells for Patients With Chemotherapy Resistant or Refractory CD19+ Acute LeukemiaNo drug interventionstreatment1unknown_status
NCT06076226
A Retrospective Study on the Relationship Between Donor Leukocyte Telomere Length and Prognosis of Acute Leukemia Patients Treated With Allogeneic Hematopoietic Stem Cell TransplantationNo drug interventionsNot AvailableNot Availablerecruiting
NCT04099966
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletiontreatment2recruiting
NCT05654766
Assesment of the Functional Activity of Platelets for the Differential Diagnosis of ThrombocytopathiesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06211166
Assessment of Measurable Residual Disease in Allo-HSCT Using Digital Polymerase Chain ReactionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04182074
Monitoring the Diagnosis and Management of Acute Leukaemia In Pregnancy Study.No drug interventionsNot AvailableNot Availablecompleted
NCT01404520
Patient Activation, Counseling and Exercise - Acute Leukemia (PACE-AL)No drug interventionssupportive_careNot Availablecompleted
NCT03096782
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphomatreatment2completed
NCT02877082
Tacrolimus, Bortezomib, & Thymoglobulin in Preventing Low Toxicity GVHD in Donor Blood Stem Cell Transplant Patientsprevention2terminated
NCT01385891
Clove In The Treatment Of Relapsed Or Resistant Acute Leukemia In Childrentreatment2 / 3completed
NCT01624701
Clinical Ex Vivo Expansion of Human Umbilical Cord Blood Stem and Progenitor CellsNo drug interventionstreatment1 / 2terminated
NCT04969601
Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblingsprevention1 / 2completed
NCT05521204
Olverembatinib for FGFR1-rearranged Neoplasmstreatment2recruiting
NCT03050268
Familial Investigations of Childhood Cancer PredispositionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04157569
CtDNA After Chemotherapy in Elderly Patients With Acute LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02487069
Allo-HSCT With Alternative Donor in Treatment of Hematologic MalignancyNo drug interventionstreatmentNot Availablecompleted
NCT01695512
Diagnostic Study of Combined Biomnarker Testing in Bronchoalveolar Lavage Samples of Immunocompromised PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01336712
Total Body Irradiation/Fludarabine Based Ablative Haploidentical Transplant for Hematologic DiseasesNo drug interventionstreatment2completed
NCT04552912
Physical Activity to Improve Patient Reported Outcomes for Adults With Acute LeukemiaNo drug interventionssupportive_careNot Availablecompleted
NCT05601895
The Gut Microbiome in FLT3- AL Undergoing Allo-HSCT With Or Without Sorafenib MaintenanceNo drug interventionsNot AvailableNot Availablerecruiting
NCT01472055
Pharmacokinetic Study of Fludarabine in Pediatric Hematopoietic Stem Cell TransplantationNo drug interventionstreatment2unknown_status
NCT01214655
A Study for Patients With Acute LeukemiaNo drug interventionstreatment1terminated
NCT06421155
Brain MRF in Children, Adolescents and Young Adults With Acute LeukemiaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT05068401
Cryopreserved MMUD BM With PTCy for Hematologic Malignanciestreatment1not_yet_recruiting
NCT00914628
Efficacy Study on the Strategy of HSV-Tk Engineering Donor Lymphocytes to Treat Patients With High Risk Acute LeukemiaNo drug interventionstreatment3terminated
NCT02990104
First Report, Five Years Experience of the Acute Leukemia Work GroupNo drug interventionsNot AvailableNot Availableunknown_status