Multiple Sclerosis, Relapsing Forms of Multiple Sclerosis

Also known as: Relapsing multiple sclerosis (MS) / Relapsing Multiple Sclerosis (RMS) / Multiple Sclerosis, Relapsing Forms / Multiple Sclerosis, Relapsing / Relapsing Multiple Sclerosis / Relapsing Forms of Multiple Sclerosis / Multiple sclerosis relapse / Multiple sclerosis flare

DrugDrug NameDrug Description
DB00242CladribineA purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs.
DB00111DaclizumabA monoclonal anti-CD25 antibody that blocks the interleukin-2 receptor which is used to treat relapsing forms of multiple sclerosis.
DB14783Diroximel fumarateA drug used for the treatment of relapsing forms of Multiple Sclerosis (MS).
DB08868FingolimodA sphingosine 1-phosphate receptor modulator used to treat patients with the relapsing-remitting form of multiple sclerosis (MS) and studied to manage lung complications of COVID-19.
DB00060Interferon beta-1aA form of recombinant human interferon used to slow disease progression and reduce the frequency of clinical symptoms in patients who have relapsing multiple sclerosis.
DB00068Interferon beta-1bA form of recombinant human interferon used to slow the progression of relapsing multiple sclerosis and to reduce the frequency of clinical symptoms.
DB11988OcrelizumabA CD20 specific monoclonal antibody used to treat relapsing remitting multiple sclerosis.
DB06650OfatumumabAn anti-CD20 antibody used for the treatment of chronic lymphocytic leukemia (CLL) in selected patients with certain treatment histories and responsiveness to anticancer medications.
DB12612OzanimodA sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD).
DB09122Peginterferon beta-1aAn interferon beta used to treat relapsing forms of multiple sclerosis.
DB12016PonesimodA sphingosine 1-phosphate receptor modulator indicated to treat relapsing multiple sclerosis.
DB12371SiponimodA medication used to treat relapsing multiple sclerosis.
DrugDrug NameTargetType
DB00242CladribinePurine nucleoside phosphorylasetarget
DB00242CladribineDNAtarget
DB00242CladribineDeoxycytidine kinaseenzyme
DB00242CladribineRibonucleoside-diphosphate reductase large subunittarget
DB00242CladribineRibonucleoside-diphosphate reductase subunit M2target
DB00242CladribineRibonucleoside-diphosphate reductase subunit M2 Btarget
DB00242CladribineDNA polymerase alpha catalytic subunittarget
DB00242CladribineDNA polymerase epsilon catalytic subunit Atarget
DB00242CladribineDNA polymerase epsilon subunit 2target
DB00242CladribineDNA polymerase epsilon subunit 3target
DB00242CladribineDNA polymerase epsilon subunit 4target
DB00242CladribineATP-binding cassette sub-family G member 2transporter
DB00242CladribineSolute carrier family 28 member 3transporter
DB00111DaclizumabInterleukin-2 receptor subunit alphatarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00111DaclizumabComplement C1r subcomponenttarget
DB00111DaclizumabComplement C1q subcomponent subunit Atarget
DB00111DaclizumabComplement C1q subcomponent subunit Btarget
DB00111DaclizumabComplement C1q subcomponent subunit Ctarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00111DaclizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00111DaclizumabInterleukin-2 receptor subunit betatarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00111DaclizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB14783Diroximel fumarateNeuronal acetylcholine receptor subunit alpha-10target
DB08868FingolimodSphingosine 1-phosphate receptor 5target
DB08868FingolimodSphingosine kinase 1enzyme
DB08868FingolimodCytochrome P450 2E1enzyme
DB08868FingolimodLeukotriene-B(4) omega-hydroxylase 1enzyme
DB08868FingolimodHistone deacetylase 1target
DB08868FingolimodExcitatory amino acid transporter 2transporter
DB08868FingolimodExcitatory amino acid transporter 1transporter
DB08868FingolimodP-glycoprotein 1transporter
DB08868FingolimodMultidrug resistance-associated protein 1transporter
DB08868FingolimodSphingosine 1-phosphate receptor 1target
DB08868FingolimodSphingosine 1-phosphate receptor 4target
DB08868FingolimodSphingosine 1-phosphate receptor 3target
DB00060Interferon beta-1aInterferon alpha/beta receptor 1target
DB00060Interferon beta-1aInterferon alpha/beta receptor 2target
DB00060Interferon beta-1aCytochrome P450 1A2enzyme
DB00068Interferon beta-1bInterferon alpha/beta receptor 1target
DB00068Interferon beta-1bInterferon alpha/beta receptor 2target
DB00068Interferon beta-1bCytochrome P450 1A2enzyme
DB11988OcrelizumabB-lymphocyte antigen CD20target
DB06650OfatumumabB-lymphocyte antigen CD20target
DB12612OzanimodSphingosine 1-phosphate receptor 1target
DB12612OzanimodSphingosine 1-phosphate receptor 5target
DB12612OzanimodAmine oxidase [flavin-containing] Btransporter
DB12612OzanimodATP-binding cassette sub-family G member 2transporter
DB12612OzanimodP-glycoprotein 1transporter
DB12612OzanimodFatty aldehyde dehydrogenaseenzyme
DB12612OzanimodAlcohol dehydrogenase class-3enzyme
DB12612OzanimodArylamine N-acetyltransferase 2enzyme
DB12612OzanimodCytochrome P450 2C8enzyme
DB12612OzanimodAmine oxidase [flavin-containing] Benzyme
DB12612OzanimodAldo-keto reductase family 1 member C1enzyme
DB12612OzanimodAldo-keto reductase family 1 member C2enzyme
DB12612OzanimodCytochrome P450 3A4enzyme
DB09122Peginterferon beta-1aCytochrome P450 1A2enzyme
DB09122Peginterferon beta-1aInterferon alpha/beta receptor 1target
DB12016PonesimodSphingosine 1-phosphate receptor 1target
DB12016PonesimodCytochrome P450 2J2enzyme
DB12016PonesimodCytochrome P450 3A4enzyme
DB12016PonesimodCytochrome P450 3A5enzyme
DB12016PonesimodCytochrome P450 4F3enzyme
DB12016PonesimodCytochrome P450 4F12enzyme
DB12016PonesimodUDP-glucuronosyltransferase 1-1enzyme
DB12016PonesimodUDP-glucuronosyltransferase 2B7enzyme
DB12371SiponimodSphingosine 1-phosphate receptor 5target
DB12371SiponimodSphingosine 1-phosphate receptor 1target
DB12371SiponimodCytochrome P450 3A4enzyme
DB12371SiponimodCytochrome P450 2C9enzyme
DrugDrug NamePhaseStatusCount
DB00108Natalizumab0Completed1
DB00242Cladribine1Completed1
DB00242Cladribine1Recruiting1
DB00977Ethinylestradiol1Completed1
DB00977Ethinylestradiol1Recruiting1
DB12530Inebilizumab1Completed1
DB00367Levonorgestrel1Completed1
DB00367Levonorgestrel1Recruiting1
DB05092CDP3231 / 2Completed1
DB06399Atacicept2Terminated2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)2Completed1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)2Completed1
DB08908Dimethyl fumarate2Completed1
DB14785Fenebrutinib2Recruiting1
DB05259Glatiramer2Not Yet Recruiting1
DB00060Interferon beta-1a2Not Yet Recruiting1
DB00068Interferon beta-1b2Not Yet Recruiting1
DB06685Laquinimod2Withdrawn1
DB10061Meningococcal (groups A, C, Y and W-135) oligosaccharide diphtheria CRM197 conjugate vaccine2Completed1
DB13889Meningococcal polysaccharide vaccine group A2Completed1
DB13890Meningococcal polysaccharide vaccine group C2Completed1
DB13887Meningococcal polysaccharide vaccine group W-1352Completed1
DB13888Meningococcal polysaccharide vaccine group Y2Completed1
DB01204Mitoxantrone2Withdrawn1
DB00108Natalizumab2Terminated1
DB06650Ofatumumab2Completed1
DB09122Peginterferon beta-1a2Not Yet Recruiting1
DB10319Streptococcus pneumoniae type 1 capsular polysaccharide antigen2Completed1
DB10329Streptococcus pneumoniae type 10a capsular polysaccharide antigen2Completed1
DB10330Streptococcus pneumoniae type 11a capsular polysaccharide antigen2Completed1
DB10331Streptococcus pneumoniae type 12f capsular polysaccharide antigen2Completed1
DB10332Streptococcus pneumoniae type 14 capsular polysaccharide antigen2Completed1
DB10333Streptococcus pneumoniae type 15b capsular polysaccharide antigen2Completed1
DB10334Streptococcus pneumoniae type 17f capsular polysaccharide antigen2Completed1
DB10335Streptococcus pneumoniae type 18c capsular polysaccharide antigen2Completed1
DB10337Streptococcus pneumoniae type 19a capsular polysaccharide antigen2Completed1
DB10336Streptococcus pneumoniae type 19f capsular polysaccharide antigen2Completed1
DB10320Streptococcus pneumoniae type 2 capsular polysaccharide antigen2Completed1
DB10338Streptococcus pneumoniae type 20 capsular polysaccharide antigen2Completed1
DB10339Streptococcus pneumoniae type 22f capsular polysaccharide antigen2Completed1
DB10340Streptococcus pneumoniae type 23f capsular polysaccharide antigen2Completed1
DB10321Streptococcus pneumoniae type 3 capsular polysaccharide antigen2Completed1
DB10341Streptococcus pneumoniae type 33f capsular polysaccharide antigen2Completed1
DB10322Streptococcus pneumoniae type 4 capsular polysaccharide antigen2Completed1
DB10323Streptococcus pneumoniae type 5 capsular polysaccharide antigen2Completed1
DB10324Streptococcus pneumoniae type 6b capsular polysaccharide antigen2Completed1
DB10325Streptococcus pneumoniae type 7f capsular polysaccharide antigen2Completed1
DB10326Streptococcus pneumoniae type 8 capsular polysaccharide antigen2Completed1
DB10327Streptococcus pneumoniae type 9n capsular polysaccharide antigen2Completed1
DB10328Streptococcus pneumoniae type 9v capsular polysaccharide antigen2Completed1
DB09145Water2Not Yet Recruiting1
DB12612Ozanimod2 / 3Completed1
DB00087Alemtuzumab3Recruiting1
DB00242Cladribine3Recruiting2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed1
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Recruiting1
DB00967Desloratadine3Active Not Recruiting1
DB01234Dexamethasone3Active Not Recruiting1
DB08908Dimethyl fumarate3Withdrawn1
DB01075Diphenhydramine3Active Not Recruiting1
DB14783Diroximel fumarate3Recruiting1
DB15170Evobrutinib3Active Not Recruiting2
DB14785Fenebrutinib3Recruiting2
DB08868Fingolimod3Completed3
DB01050Ibuprofen3Completed1
DB00060Interferon beta-1a3Active Not Recruiting2
DB00060Interferon beta-1a3Completed6
DB05299Keyhole limpet hemocyanin3Recruiting1
DB06685Laquinimod3Terminated2
DB00959Methylprednisolone3Active Not Recruiting1
DB00788Naproxen3Completed1
DB00108Natalizumab3Recruiting1
DB11988Ocrelizumab3Active Not Recruiting4
DB11988Ocrelizumab3Recruiting1
DB06650Ofatumumab3Completed1
DB06650Ofatumumab3Recruiting5
DB12612Ozanimod3Completed1
DB09122Peginterferon beta-1a3Completed3
DB16852Remibrutinib3Recruiting2
DB00073Rituximab3Recruiting2
DB12371Siponimod3Completed1
DB08880Teriflunomide3Active Not Recruiting4
DB08880Teriflunomide3Completed3
DB08880Teriflunomide3Recruiting4
DB11850Ublituximab3Completed2
DB11850Ublituximab3Enrolling by Invitation1
DB09145Water3Completed1
DB08908Dimethyl fumarate4Completed1
DB08868Fingolimod4Completed2
DB08868Fingolimod4Recruiting1
DB05259Glatiramer4Completed1
DB05259Glatiramer4Recruiting1
DB14999Human interferon beta4Withdrawn1
DB00060Interferon beta-1a4Completed2
DB00060Interferon beta-1a4Withdrawn1
DB00068Interferon beta-1b4Completed1
DB00068Interferon beta-1b4Withdrawn1
DB00108Natalizumab4Terminated1
DB11988Ocrelizumab4Active Not Recruiting1
DB11988Ocrelizumab4Recruiting2
DB06650Ofatumumab4Recruiting3
DB09122Peginterferon beta-1a4Withdrawn1
DB08880Teriflunomide4Completed1
DB09145Water4Completed1
DB08908Dimethyl fumarateNot AvailableCompleted1
DB05259GlatiramerNot AvailableCompleted1
DB00060Interferon beta-1aNot AvailableCompleted3
DB00108NatalizumabNot AvailableCompleted1
DB11988OcrelizumabNot AvailableCompleted1
DB06650OfatumumabNot AvailableCompleted1
DB09122Peginterferon beta-1aNot AvailableCompleted1