Acute Myocardial Infarction (AMI)

Also known as: Acute Myocardial Infarctus / Acute Myocardial Infarct / Myocardial Infarction, Acute / Acute Myocardial Infarction / Acute myocardial infarction NOS / Acute transmural myocardial infarction of unspecified site / Acute myocardial infarction, unspecified site, episode of care unspecified / Acute myocardial infarction, unspecified site / Myocardial infarction acute

DrugDrug NameDrug Description
DB00009AlteplaseA recombinant form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
DB00758ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB00722LisinoprilAn ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction.
DB09282MolsidomineThe indications for use of molsidomine include ischemic heart disease, angina, chronic heart failure, and pulmonary hypertension [L1370, L1371].
DB00015ReteplaseA purified form of human tissue plasminogen activator used in the emergency treatment of myocardial infarction, ischemic stroke, and pulmonary emboli.
DB00086StreptokinaseA purified fibrinolytic bacterial protein used to breakdown thrombosis in myocardial infarction, pulmonary embolism, and venous thromboembolism.
DB13166ZofenoprilZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
DrugDrug NameTargetType
DB00009AlteplaseUrokinase plasminogen activator surface receptortarget
DB00009AlteplaseFibrinogen alpha chaintarget
DB00009AlteplasePlasminogentarget
DB00009AlteplasePlasminogen activator inhibitor 1target
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP-glycoprotein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB00722LisinoprilAngiotensin-converting enzymetarget
DB00722LisinoprilSolute carrier family 15 member 1transporter
DB00722LisinoprilSolute carrier family 15 member 2transporter
DB00722LisinoprilRenintarget
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2target
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
DB09282MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
DB00015ReteplaseFibrinogen alpha chaintarget
DB00015ReteplasePlasminogentarget
DB00015ReteplasePlasminogen activator inhibitor 1target
DB00086StreptokinasePlasminogentarget
DB00086StreptokinaseProteinase-activated receptor 1target
DB00086StreptokinaseCytosolic phospholipase A2enzyme
DB13166ZofenoprilAngiotensin-converting enzymetarget
DrugDrug NamePhaseStatusCount
DB00264Metoprolol1Completed1
DB00683Midazolam1Completed1
DB15742MultiStem1Completed1
DB00058Alpha-1-proteinase inhibitor1 / 2Completed1
DB00099Filgrastim1 / 2Completed1
DB00054Abciximab2Unknown Status1
DB00026Anakinra2Completed1
DB14547Chloride ion2Completed1
DB00091Cyclosporine2Withdrawn1
DB11723Dutogliptin2Enrolling by Invitation1
DB00063Eptifibatide2Unknown Status1
DB00016Erythropoietin2Completed1
DB00016Erythropoietin2Unknown Status1
DB00099Filgrastim2Completed1
DB00099Filgrastim2Enrolling by Invitation1
DB05549INO-10012Completed1
DB01065Melatonin2Completed1
DB01065Melatonin2Terminated1
DB09107Methoxy polyethylene glycol-epoetin beta2Completed1
DB04899Nesiritide2Completed1
DB00435Nitric Oxide2Completed1
DB00435Nitric Oxide2Terminated1
DB09152Nitrogen2Terminated1
DB09112Nitrous acid2Completed1
DB01098Rosuvastatin2Unknown Status1
DB15163Selatogrel2Completed1
DB01236Sevoflurane2Completed1
DB00641Simvastatin2Unknown Status1
DB09153Sodium chloride2Recruiting1
DB02772Sucrose2Recruiting1
DB00031Tenecteplase2Completed1
DB12003Thymosin beta-42Suspended1
DB06151Acetylcysteine2 / 3Completed1
DB00945Acetylsalicylic acid2 / 3Unknown Status1
DB00026Anakinra2 / 3Completed1
DB01394Colchicine2 / 3Not Yet Recruiting1
DB00254Doxycycline2 / 3Unknown Status1
DB11242Gelatin2 / 3Unknown Status1
DB00123L-Lysine2 / 3Unknown Status1
DB13144Lenograstim2 / 3Unknown Status1
DB01261Sitagliptin2 / 3Unknown Status1
DB00054Abciximab3Terminated1
DB00640Adenosine3Completed1
DB06605Apixaban3Recruiting1
DB00006Bivalirudin3Terminated1
DB00006Bivalirudin3Unknown Status1
DB00758Clopidogrel3Completed1
DB00091Cyclosporine3Completed1
DB06292Dapagliflozin3Not Yet Recruiting1
DB00012Darbepoetin alfa3Completed1
DB09038Empagliflozin3Recruiting1
DB01225Enoxaparin3Completed1
DB08917Ferric carboxymaltose3Recruiting1
DB01109Heparin3Completed1
DB01109Heparin3Terminated1
DB01109Heparin3Unknown Status1
DB00028Human immunoglobulin G3Completed1
DB00295Morphine3Completed1
DB09140Oxygen3Completed1
DB04949Pexelizumab3Completed1
DB00178Ramipril3Active Not Recruiting1
DB09292Sacubitril3Active Not Recruiting1
DB00086Streptokinase3Completed1
DB08816Ticagrelor3Completed1
DB00775Tirofiban3Completed1
DB00177Valsartan3Active Not Recruiting1
DB00682Warfarin3Recruiting1
DB00054Abciximab4Completed3
DB06151Acetylcysteine4Completed1
DB00945Acetylsalicylic acid4Active Not Recruiting1
DB00945Acetylsalicylic acid4Completed1
DB01076Atorvastatin4Completed2
DB01076Atorvastatin4Recruiting1
DB01393Bezafibrate4Completed1
DB00612Bisoprolol4Recruiting2
DB00006Bivalirudin4Completed1
DB06441Cangrelor4Recruiting1
DB01136Carvedilol4Recruiting1
DB01166Cilostazol4Active Not Recruiting2
DB00758Clopidogrel4Active Not Recruiting2
DB00758Clopidogrel4Completed3
DB00758Clopidogrel4Terminated2
DB00758Clopidogrel4Withdrawn1
DB01394Colchicine4Unknown Status2
DB00343Diltiazem4Completed1
DB00016Erythropoietin4Completed1
DB00016Erythropoietin4Unknown Status1
DB00736Esomeprazole4Completed2
DB00973Ezetimibe4Recruiting1
DB00927Famotidine4Completed2
DB01109Heparin4Completed1
DB00159Icosapent4Unknown Status1
DB08887Icosapent ethyl4Unknown Status1
DB00047Insulin glargine4Completed1
DB00030Insulin human4Completed1
DB00046Insulin lispro4Completed1
DB01249Iodixanol4Completed1
DB09156Iopromide4Completed1
DB01233Metoclopramide4Completed1
DB00264Metoprolol4Completed1
DB00264Metoprolol4Recruiting2
DB00295Morphine4Completed1
DB04861Nebivolol4Recruiting1
DB00727Nitroglycerin4Completed1
DB00175Pravastatin4Unknown Status1
DB00015Reteplase4Completed2
DB09153Sodium chloride4Completed1
DB00086Streptokinase4Completed2
DB00031Tenecteplase4Terminated1
DB08816Ticagrelor4Completed1
DB08816Ticagrelor4Recruiting1
DB08816Ticagrelor4Terminated1
DB00775Tirofiban4Completed4
DB00775Tirofiban4Unknown Status1
DB00661Verapamil4Completed1
DB00316AcetaminophenNot AvailableWithdrawn1
DB06151AcetylcysteineNot AvailableCompleted1
DB00945Acetylsalicylic acidNot AvailableActive Not Recruiting1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB01076AtorvastatinNot AvailableUnknown Status1
DB00796Candesartan cilexetilNot AvailableTerminated1
DB01136CarvedilolNot AvailableCompleted1
DB00758ClopidogrelNot AvailableActive Not Recruiting1
DB00115CyanocobalaminNot AvailableCompleted1
DB01225EnoxaparinNot AvailableCompleted1
DB00813FentanylNot AvailableCompleted1
DB00158Folic acidNot AvailableCompleted1
DB01109HeparinNot AvailableCompleted1
DB10773Influenza A virus A/California/7/2009 (H1N1) recombinant hemagglutinin antigenNot AvailableRecruiting1
DB14417Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigenNot AvailableRecruiting1
DB14423Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigenNot AvailableRecruiting1
DB10774Influenza A virus A/Victoria/361/2011 (H3N2) recombinant hemagglutinin antigenNot AvailableRecruiting1
DB14418Influenza B virus B/Brisbane/60/2008 recombinant hemagglutinin antigenNot AvailableRecruiting1
DB10779Influenza B virus B/Phuket/3073/2013 recombinant hemagglutinin antigenNot AvailableRecruiting1
DB10775Influenza B virus B/Wisconsin/1/2010 recombinant hemagglutinin antigenNot AvailableRecruiting1
DB06655LiraglutideNot AvailableUnknown Status1
DB00295MorphineNot AvailableCompleted1
DB09220NicorandilNot AvailableCompleted2
DB06209PrasugrelNot AvailableCompleted1
DB00165PyridoxineNot AvailableCompleted1
DB09292SacubitrilNot AvailableRecruiting1
DB01390Sodium bicarbonateNot AvailableCompleted1
DB00966TelmisartanNot AvailableTerminated1
DB08816TicagrelorNot AvailableActive Not Recruiting1
DB08816TicagrelorNot AvailableCompleted2
DB00177ValsartanNot AvailableRecruiting1