Polycystic Ovarian Syndrome

Also known as: PCOS / Sclerocystic ovary syndrome / Stein-Leventhal syndrome / Multicystic ovaries / Polycystic ovaries / Polycystic ovary / Polycystic Ovary Syndrome

DrugDrug NameDrug Description
DB01395DrospirenoneA progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.
DB00823Ethynodiol diacetateAn oral contraceptive used to prevent pregnancy.
DB01216FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
DB01006LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
DB01357MestranolA synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
DB06713NorelgestrominA progestin used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception.
DB00957NorgestimateA progesterone used as a contraceptive and to treat acne vulgaris.
DB09389NorgestrelA progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
DrugDrug NameTargetType
DB01395DrospirenoneProgesterone receptortarget
DB01395DrospirenoneMineralocorticoid receptortarget
DB01395DrospirenoneAndrogen receptortarget
DB01395DrospirenoneProstaglandin G/H synthase 2enzyme
DB01395DrospirenoneSerum paraoxonase/arylesterase 1enzyme
DB01395DrospirenoneGlucocorticoid receptortarget
DB01395DrospirenoneCytochrome P450 3A4enzyme
DB00823Ethynodiol diacetateEstrogen receptor alphatarget
DB00823Ethynodiol diacetateProgesterone receptortarget
DB00823Ethynodiol diacetateCytochrome P450 3A4enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01216FinasterideCytochrome P450 3A4enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01216Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
DB01216FinasterideCytochrome P450 3A5enzyme
DB01216FinasterideCytochrome P450 3A7enzyme
DB01216FinasterideSolute carrier family 12 member 5transporter
DB01006LetrozoleCytochrome P450 19A1target
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleCytochrome P450 19A1enzyme
DB01006LetrozoleCytochrome P450 2C19enzyme
DB01006LetrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01006LetrozoleSerum albumincarrier
DB01006LetrozoleP-glycoprotein 1transporter
DB01357MestranolEstrogen receptor alphatarget
DB01357MestranolCytochrome P450 2C9enzyme
DB01357MestranolCytochrome P450 3A4enzyme
DB01357MestranolCytochrome P450 2C8enzyme
DB06713NorelgestrominSteryl-sulfataseenzyme
DB06713NorelgestrominProgesterone receptortarget
DB06713NorelgestrominSerum albumintarget
DB06713NorelgestrominAndrogen receptortarget
DB06713NorelgestrominCytochrome P450 3A4enzyme
DB00957NorgestimateProgesterone receptortarget
DB00957NorgestimateEstrogen receptor alphatarget
DB00957NorgestimateCanalicular multispecific organic anion transporter 1transporter
DB00957NorgestimateCytochrome P450 3A4enzyme
DB00957NorgestimateAndrogen receptortarget
DB00957NorgestimateCytochrome P450 2B6enzyme
DB00957NorgestimateCytochrome P450 2C9enzyme
DB00957NorgestimateUDP-glucuronosyltransferase 1-1enzyme
DB00957NorgestimateSerum albumincarrier
DB00957NorgestimateSex hormone-binding globulincarrier
DB00957NorgestimateP-glycoprotein 1transporter
DB09389NorgestrelProgesterone receptortarget
DB09389Norgestrel3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB09389NorgestrelAndrogen receptortarget
DB09389NorgestrelCytochrome P450 3A4enzyme
DB09389NorgestrelCytochrome P450 19A1enzyme
DrugDrug NamePhaseStatusCount
DB00158Folic acid0Not Yet Recruiting1
DB13178Inositol0Not Yet Recruiting1
DB00331Metformin0Completed1
DB00331Metformin0Not Yet Recruiting1
DB00331Metformin0Recruiting1
DB00331Metformin0Unknown Status1
DB01132Pioglitazone0Completed1
DB00882Clomifene1Unknown Status1
DB00644Gonadorelin1Recruiting1
DB00331Metformin1Recruiting1
DB00396Progesterone1Recruiting1
DB08842Acetylcarnitine2Completed1
DB06151Acetylcysteine2Completed1
DB00882Clomifene2Completed1
DB00882Clomifene2Unknown Status1
DB04839Cyproterone acetate2Completed1
DB04839Cyproterone acetate2Unknown Status1
DB00977Ethinylestradiol2Completed1
DB00977Ethinylestradiol2Unknown Status1
DB01050Ibuprofen2Enrolling by Invitation1
DB00583Levocarnitine2Completed2
DB00331Metformin2Completed4
DB01132Pioglitazone2Completed1
DB11094Vitamin D2Completed1
DB15350D-chiro-Inositol2 / 3Completed1
DB01276Exenatide2 / 3Active Not Recruiting1
DB13178Inositol2 / 3Completed1
DB00331Metformin2 / 3Completed1
DB13928Semaglutide2 / 3Recruiting1
DB00421Spironolactone2 / 3Completed1
DB01200Bromocriptine3Unknown Status1
DB00050Cetrorelix3Completed2
DB00097Choriogonadotropin alfa3Completed2
DB09126Chorionic Gonadotropin (Human)3Completed2
DB06699Degarelix3Completed1
DB01234Dexamethasone3Completed1
DB00158Folic acid3Unknown Status1
DB00066Follitropin3Completed1
DB09024Follitropin3Completed1
DB00644Gonadorelin3Completed1
DB13178Inositol3Unknown Status1
DB01006Letrozole3Completed1
DB00331Metformin3Completed1
DB00331Metformin3Recruiting1
DB00284Acarbose4Unknown Status1
DB00169Cholecalciferol4Terminated1
DB09126Chorionic Gonadotropin (Human)4Recruiting1
DB09126Chorionic Gonadotropin (Human)4Withdrawn1
DB00882Clomifene4Completed3
DB00882Clomifene4Recruiting2
DB04839Cyproterone acetate4Unknown Status1
DB01395Drospirenone4Completed1
DB01395Drospirenone4Unknown Status1
DB00977Ethinylestradiol4Completed2
DB00977Ethinylestradiol4Unknown Status1
DB01276Exenatide4Unknown Status1
DB00158Folic acid4Completed1
DB00158Folic acid4Recruiting1
DB00066Follitropin4Completed1
DB00644Gonadorelin4Unknown Status1
DB13178Inositol4Completed1
DB01006Letrozole4Completed1
DB01006Letrozole4Recruiting1
DB00007Leuprolide4Completed1
DB06655Liraglutide4Completed5
DB06655Liraglutide4Recruiting1
DB00032Menotropins4Completed1
DB00331Metformin4Completed9
DB00331Metformin4Terminated3
DB00331Metformin4Unknown Status3
DB01083Orlistat4Unknown Status1
DB00860Prednisolone4Recruiting1
DB00396Progesterone4Completed1
DB01656Roflumilast4Completed2
DB13928Semaglutide4Recruiting1
DB01261Sitagliptin4Completed1
DB00675Tamoxifen4Completed1
DB11094Vitamin D4Recruiting1
DB11094Vitamin D4Terminated1
DB09145Water4Completed1
DB00248CabergolineNot AvailableCompleted1
DB01373CalciumNot AvailableCompleted1
DB00882ClomifeneNot AvailableCompleted1
DB00882ClomifeneNot AvailableTerminated1
DB00882ClomifeneNot AvailableUnknown Status1
DB06699DegarelixNot AvailableUnknown Status1
DB01119DiazoxideNot AvailableCompleted1
DB13956Estradiol valerateNot AvailableCompleted1
DB00644GonadorelinNot AvailableUnknown Status1
DB01006LetrozoleNot AvailableUnknown Status2
DB00603Medroxyprogesterone acetateNot AvailableCompleted1
DB00603Medroxyprogesterone acetateNot AvailableTerminated1
DB00331MetforminNot AvailableCompleted1
DB00331MetforminNot AvailableUnknown Status1
DB00393NimodipineNot AvailableCompleted1
DB00396ProgesteroneNot AvailableCompleted1
DB00481RaloxifeneNot AvailableTerminated1
DB11094Vitamin DNot AvailableCompleted1