Infections, Fungal

Also known as: Fungal Infection / Fungal infections / Infection, Fungal / Infection fungal / Mycoses / (Dermatophytosis &/or tinea &/or ringworm) or (fungal infections) or (mycoses) / Mycosis (disorder) / Mycoses NOS (disorder) / Mycosis / Fungal infection NOS / Fungemia NOS / Infection mycotic / Fungal infectious disorders / Infection fungal (mycotic) / [X]Unspecified mycosis (disorder)

DrugDrug NameDrug Description
DB00681Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
DB03793Benzoic acidAn antimicrobial food additive.
DB04794BifonazoleAn azole antifungal drug used to treat fungal skin infections, such as dermatomycosis.
DB00520CaspofunginAn echinocandin used to treat a variety of fungal infections.
DB01243ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
DB00196FluconazoleA triazole antifungal used to treat various fungal infections including candidiasis.
DB01099FlucytosineAn antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
DB00406Gentian violet cationAn antiseptic violet dye used to prevent various infections, including fungal and bacterial infections.
DB01167ItraconazoleAn antifungal agent used for the treatment of various fungal infections in immunocompromised and non-immunocompromised patients, such as pulmonary and extrapulmonary blastomycosis, histoplasmosis, and onychomycosis.
DB01026KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
DB01141MicafunginAn antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
DB01263PosaconazoleA triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
DB00936Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DB00582VoriconazoleA triazole compound used to treat fungal infections.
DrugDrug NameTargetType
DB00681Amphotericin BErgosteroltarget
DB03793Benzoic acidCocaine esterasetarget
DB03793Benzoic acidD-amino-acid oxidasetarget
DB03793Benzoic acidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic acidNon-heme chloroperoxidasetarget
DB03793Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic acidReplication proteintarget
DB03793Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic acidSolute carrier family 22 member 8transporter
DB03793Benzoic acidMonocarboxylate transporter 1transporter
DB03793Benzoic acidSolute carrier family 15 member 1target
DB04794BifonazoleCytochrome P450 2B6target
DB04794BifonazoleCytochrome P450 51target
DB04794BifonazoleCytochrome P450 19A1enzyme
DB04794BifonazoleCytochrome P450 2E1enzyme
DB04794BifonazoleCytochrome P450 3A4enzyme
DB00520CaspofunginSolute carrier family 22 member 1transporter
DB00520CaspofunginP-glycoprotein 1transporter
DB00520CaspofunginSolute carrier family 22 member 6transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B1transporter
DB00520CaspofunginSolute carrier organic anion transporter family member 1B3transporter
DB00520CaspofunginCytochrome P450 3A4enzyme
DB00520Caspofungin1,3-beta-glucan synthase component FKS1target
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleP-glycoprotein 1transporter
DB00196FluconazoleCytochrome P450 51target
DB00196FluconazoleCytochrome P450 3A5enzyme
DB01099FlucytosineThymidylate synthasetarget
DB01099FlucytosineDNA (cytosine-5)-methyltransferase 1target
DB01099FlucytosineDNAtarget
DB00406Gentian violet cationDNAtarget
DB00406Gentian violet cationSolute carrier family 22 member 1transporter
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleLanosterol 14-alpha demethylasetarget
DB01167ItraconazoleCytochrome P450 3A4enzyme
DB01167ItraconazoleCytochrome P450 3A5enzyme
DB01167ItraconazoleCytochrome P450 3A7enzyme
DB01167ItraconazoleCytochrome P450 2B6enzyme
DB01167ItraconazoleP-glycoprotein 1transporter
DB01167ItraconazoleCytochrome P450 1A1enzyme
DB01167ItraconazoleCytochrome P450 2E1enzyme
DB01167ItraconazoleSolute carrier organic anion transporter family member 2B1transporter
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleP-glycoprotein 1transporter
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01026KetoconazoleSerum albumincarrier
DB01026KetoconazoleSex hormone-binding globulincarrier
DB01026KetoconazoleCytochrome P450 19A1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
DB01141MicafunginArylsulfatase Aenzyme
DB01141MicafunginCatechol O-methyltransferaseenzyme
DB01141Micafungin1,3-beta-glucan synthase component FKS1target
DB01263PosaconazoleCytochrome P450 3A4enzyme
DB01263PosaconazoleP-glycoprotein 1transporter
DB01263PosaconazoleCytochrome P450 51target
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DB00582VoriconazoleCytochrome P450 2C19enzyme
DB00582VoriconazoleCytochrome P450 3A4enzyme
DB00582VoriconazoleCytochrome P450 2C9enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB00582VoriconazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00582VoriconazoleCytochrome P450 3A5enzyme
DB00582VoriconazoleCytochrome P450 3A7enzyme
DB00582VoriconazoleProstaglandin G/H synthase 1enzyme
DB00582VoriconazoleCytochrome P450 51target
DB00582VoriconazoleCytochrome P450 2B6enzyme
DrugDrug NamePhaseStatusCount
DB00254Doxycycline1Completed1
DB06414Etravirine1Completed1
DB00196Fluconazole1Completed1
DB01319Fosamprenavir1Completed1
DB15183Fosmanogepix1Completed4
DB12471Ibrexafungerp1Completed1
DB01167Itraconazole1Completed1
DB01141Micafungin1Completed2
DB01263Posaconazole1Completed6
DB01263Posaconazole1Terminated1
DB16310Rezafungin1Terminated1
DB01045Rifampicin1Completed1
DB00503Ritonavir1Completed1
DB00582Voriconazole1Completed5
DB16555Lactoferrin1 / 2Withdrawn1
DB00520Caspofungin2Completed4
DB00520Caspofungin2Unknown Status1
DB00196Fluconazole2Completed1
DB01073Fludarabine2Recruiting1
DB14158Microcrystalline cellulose2Completed1
DB12277Polihexanide2Recruiting1
DB15677Polyaminopropyl biguanide2Recruiting1
DB01263Posaconazole2Completed1
DB01263Posaconazole2Unknown Status1
DB16310Rezafungin2Completed1
DB04572Thiotepa2Recruiting1
DB11678Treosulfan2Recruiting1
DB00257Clotrimazole2 / 3Completed1
DB00826Natamycin2 / 3Unknown Status1
DB00582Voriconazole2 / 3Unknown Status1
DB00681Amphotericin B3Completed2
DB00520Caspofungin3Active Not Recruiting2
DB00520Caspofungin3Completed6
DB00257Clotrimazole3Unknown Status1
DB00196Fluconazole3Active Not Recruiting2
DB00196Fluconazole3Completed1
DB00196Fluconazole3Recruiting1
DB01167Itraconazole3Completed1
DB01137Levofloxacin3Completed1
DB01141Micafungin3Completed2
DB14158Microcrystalline cellulose3Active Not Recruiting1
DB14158Microcrystalline cellulose3Recruiting1
DB01263Posaconazole3Completed2
DB01263Posaconazole3Recruiting1
DB16310Rezafungin3Active Not Recruiting1
DB16310Rezafungin3Recruiting1
DB01015Sulfamethoxazole3Recruiting1
DB00440Trimethoprim3Recruiting1
DB00582Voriconazole3Active Not Recruiting1
DB00582Voriconazole3Completed2
DB00681Amphotericin B4Completed2
DB00681Amphotericin B4Terminated1
DB00362Anidulafungin4Completed1
DB00520Caspofungin4Completed1
DB01167Itraconazole4Recruiting1
DB01263Posaconazole4Completed1
DB01263Posaconazole4Recruiting1
DB01263Posaconazole4Terminated2
DB00582Voriconazole4Completed2
DB00520CaspofunginNot AvailableNot Yet Recruiting1
DB00520CaspofunginNot AvailableUnknown Status1
DB00196FluconazoleNot AvailableRecruiting1
DB01263PosaconazoleNot AvailableCompleted1
DB01263PosaconazoleNot AvailableRecruiting1
DB00582VoriconazoleNot AvailableCompleted1
DB00582VoriconazoleNot AvailableUnknown Status1