Acute Otitis Media (AOM)

Also known as: AOM - Acute Otitis Media / Acute Otitis Media / Otitis media acute / Acute otitis media (disorder) / Otitis media acute NOS / Otitis media NOS

DrugDrug NameDrug Description
DB01060AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
DB00207AzithromycinA macrolide antibiotic used to treat a variety of bacterial infections.
DB01416CefpodoximeA third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
DB01415CeftibutenA third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB00591Fluocinolone acetonideA corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB01165OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
DB00781Polymyxin BA polymyxin antibiotic used to treat a wide variety of infections in the body.
DB00263SulfisoxazoleA sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections.
DrugDrug NameTargetType
DB01060AmoxicillinSolute carrier family 15 member 1transporter
DB01060AmoxicillinSolute carrier family 15 member 2transporter
DB01060AmoxicillinSolute carrier family 22 member 6transporter
DB01060AmoxicillinCytochrome P450 2C8enzyme
DB01060AmoxicillinSerum albumincarrier
DB01060AmoxicillinBeta-lactamase 2enzyme
DB01060AmoxicillinPenicillin binding proteintarget
DB00207Azithromycin23S ribosomal RNAtarget
DB00207AzithromycinP-glycoprotein 1transporter
DB00207AzithromycinCytochrome P450 3A4enzyme
DB00207AzithromycinProtein-arginine deiminase type-4target
DB00207AzithromycinCanalicular multispecific organic anion transporter 1transporter
DB01416CefpodoximePeptidoglycan synthase FtsItarget
DB01415CeftibutenSolute carrier family 15 member 1transporter
DB01415CeftibutenSolute carrier family 15 member 2transporter
DB01415CeftibutenPeptidoglycan synthase FtsItarget
DB01415CeftibutenPenicillin-binding protein 1Atarget
DB01415CeftibutenPenicillin-binding protein 1Btarget
DB01415CeftibutenPenicillin-binding protein 2target
DB01415CeftibutenSolute carrier family 22 member 6transporter
DB01415CeftibutenSolute carrier family 22 member 8transporter
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB00591Fluocinolone acetonideCorticosteroid-binding globulincarrier
DB00591Fluocinolone acetonideGlucocorticoid receptortarget
DB00591Fluocinolone acetonideCytochrome P450 3A4enzyme
DB00591Fluocinolone acetonideAnnexin A1target
DB00591Fluocinolone acetonideAnnexin A2target
DB00591Fluocinolone acetonideAnnexin A3target
DB00591Fluocinolone acetonideAnnexin A4target
DB00591Fluocinolone acetonideAnnexin A5target
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB01165OfloxacinDNA gyrase subunit Atarget
DB01165OfloxacinDNA topoisomerase 4 subunit Atarget
DB01165OfloxacinDNA topoisomerase 2-alphatarget
DB01165OfloxacinCytochrome P450 1A2enzyme
DB01165OfloxacinSolute carrier family 22 member 5transporter
DB01165OfloxacinMultidrug resistance-associated protein 1transporter
DB01165OfloxacinSolute carrier family 22 member 6transporter
DB01165OfloxacinCanalicular multispecific organic anion transporter 1transporter
DB01165OfloxacinSolute carrier family 22 member 4transporter
DB01165OfloxacinBile salt export pumptransporter
DB00781Polymyxin BBacterial outer membranetarget
DB00781Polymyxin BSolute carrier family 15 member 2transporter
DB00263SulfisoxazoleDihydropteroate synthasetarget
DB00263SulfisoxazoleCytochrome P450 2C9enzyme
DrugDrug NamePhaseStatusCount
DB01060Amoxicillin2Completed1
DB01060Amoxicillin2Terminated1
DB01435Antipyrine2Completed1
DB00207Azithromycin2Completed1
DB01086Benzocaine2Completed2
DB00537Ciprofloxacin2Completed1
DB00537Ciprofloxacin2Terminated1
DB00766Clavulanic acid2Completed1
DB00766Clavulanic acid2Terminated1
DB01234Dexamethasone2Terminated1
DB09047Finafloxacin2Terminated1
DB00218Moxifloxacin2Completed1
DB00535Cefdinir2 / 3Completed1
DB01060Amoxicillin3Completed2
DB00207Azithromycin3Completed1
DB01086Benzocaine3Completed2
DB01086Benzocaine3Terminated1
DB10788Bordetella pertussis filamentous hemagglutinin antigen (formaldehyde inactivated)3Completed1
DB10992Bordetella pertussis pertactin antigen (formaldehyde inactivated)3Completed1
DB10991Bordetella pertussis toxoid antigen (formaldehyde, glutaraldehyde inactivated)3Completed1
DB11129Carbamide peroxide3Completed1
DB11129Carbamide peroxide3Terminated1
DB00766Clavulanic acid3Completed2
DB10583Clostridium tetani toxoid antigen (formaldehyde inactivated)3Completed1
DB16712Corynebacterium diphtheriae CRM197 protein3Active Not Recruiting1
DB10584Corynebacterium diphtheriae toxoid antigen (formaldehyde inactivated)3Completed1
DB09462Glycerin3Completed1
DB09462Glycerin3Terminated1
DB00218Moxifloxacin3Completed1
DB00218Moxifloxacin3Terminated1
DB01165Ofloxacin3Completed1
DB14007Pentetic acid3Completed1
DB14500Potassium3Completed1
DB10319Streptococcus pneumoniae type 1 capsular polysaccharide antigen3Completed1
DB10293Streptococcus pneumoniae type 1 capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10329Streptococcus pneumoniae type 10a capsular polysaccharide antigen3Completed1
DB10330Streptococcus pneumoniae type 11a capsular polysaccharide antigen3Completed1
DB10331Streptococcus pneumoniae type 12f capsular polysaccharide antigen3Completed1
DB10332Streptococcus pneumoniae type 14 capsular polysaccharide antigen3Completed1
DB10289Streptococcus pneumoniae type 14 capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10333Streptococcus pneumoniae type 15b capsular polysaccharide antigen3Completed1
DB10334Streptococcus pneumoniae type 17f capsular polysaccharide antigen3Completed1
DB10290Streptococcus pneumoniae type 18C capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10335Streptococcus pneumoniae type 18c capsular polysaccharide antigen3Completed1
DB10298Streptococcus pneumoniae type 19A capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10291Streptococcus pneumoniae type 19F capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10337Streptococcus pneumoniae type 19a capsular polysaccharide antigen3Completed1
DB10336Streptococcus pneumoniae type 19f capsular polysaccharide antigen3Completed1
DB10320Streptococcus pneumoniae type 2 capsular polysaccharide antigen3Completed1
DB10338Streptococcus pneumoniae type 20 capsular polysaccharide antigen3Completed1
DB16710Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10339Streptococcus pneumoniae type 22f capsular polysaccharide antigen3Completed1
DB10292Streptococcus pneumoniae type 23F capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10340Streptococcus pneumoniae type 23f capsular polysaccharide antigen3Completed1
DB10321Streptococcus pneumoniae type 3 capsular polysaccharide antigen3Completed1
DB10294Streptococcus pneumoniae type 3 capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB16711Streptococcus pneumoniae type 33F capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10341Streptococcus pneumoniae type 33f capsular polysaccharide antigen3Completed1
DB10322Streptococcus pneumoniae type 4 capsular polysaccharide antigen3Completed1
DB10286Streptococcus pneumoniae type 4 capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10323Streptococcus pneumoniae type 5 capsular polysaccharide antigen3Completed1
DB10295Streptococcus pneumoniae type 5 capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10296Streptococcus pneumoniae type 6A capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10287Streptococcus pneumoniae type 6B capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10324Streptococcus pneumoniae type 6b capsular polysaccharide antigen3Completed1
DB10297Streptococcus pneumoniae type 7F capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10325Streptococcus pneumoniae type 7f capsular polysaccharide antigen3Completed1
DB10326Streptococcus pneumoniae type 8 capsular polysaccharide antigen3Completed1
DB10288Streptococcus pneumoniae type 9V capsular polysaccharide diphtheria CRM197 protein conjugate antigen3Active Not Recruiting1
DB10327Streptococcus pneumoniae type 9n capsular polysaccharide antigen3Completed1
DB10328Streptococcus pneumoniae type 9v capsular polysaccharide antigen3Completed1
DB11195Xylitol3Completed1
DB01060Amoxicillin4Completed2
DB01060Amoxicillin4Recruiting1
DB01060Amoxicillin4Unknown Status1
DB00207Azithromycin4Completed1
DB00535Cefdinir4Completed2
DB00766Clavulanic acid4Completed1
DB00766Clavulanic acid4Recruiting1
DB00766Clavulanic acid4Unknown Status1
DB00471Montelukast4Completed1
DB01060AmoxicillinNot AvailableCompleted1
DB01212CeftriaxoneNot AvailableCompleted1
DB00537CiprofloxacinNot AvailableCompleted1
DB00766Clavulanic acidNot AvailableCompleted1
DB01234DexamethasoneNot AvailableCompleted1
DB01165OfloxacinNot AvailableCompleted1