Ewing's Sarcoma (DBCOND0028085)

Identifiers

Synonyms
Ewing Sarcoma of Bone / Ewing's Sarcoma (ES) / Ewing's Tumor / Ewing Sarcomas / Sarcoma, Ewing's / Ewing Tumor / Ewing's Family Tumor / Ewing's Family Tumors / Ewing Sarcoma Family Tumors / Ewing's Sarcoma Family of Tumors / Ewing Sarcoma Family of Tumors / Ewing Family of Tumors / Sarcoma, Ewing / Ewing Sarcoma / Ewing's sarcoma / Ewing's sarcoma (morphologic abnormality) / Ewing's sarcoma NOS / Ewing's sarcoma stage unspecified / Ewing's tumour / Ewing's sarcoma of bone (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Dactinomycin
An actinomycin used to treat a wide variety of cancers.
Daunorubicin
An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia.
Docetaxel
A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer.
Etoposide
A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Ifosfamide
An alkylating and immunosuppressive agent used in chemotherapy for the treatment of cancers, including testicular cancer, ovarian cancer, cervical cancer, osteocarcinoma, bladder cancer, small cell lung cancer, and non-Hodgkin's lymphoma.
Irinotecan
A topoisomerase inhibitor used to treat metastatic carcinoma of the colon or rectum and pancreatic adenocarcinoma.
Topotecan
An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
Vincristine
A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05033288
Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the BoneNo drug interventionsNot AvailableNot Availablerecruiting
NCT04845893
Observational Study on Skeletal Ewing's SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03968471
Chemotherapy-induced Necrosis in Ewing SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05395741
Regorafenib in Patients With Refractory Primary Bone Tumorstreatment1 / 2recruiting
NCT00516295
Vincristine Sulfate, Topotecan Hydrochloride, and Cyclophosphamide With or Without Bevacizumab in Treating Young Patients With Refractory or First Recurrent Extracranial Ewing Sarcomatreatment2completed
NCT01825902
18F-FLT Positron Emission Tomography and Diffusion-Weighted Magnetic Resonance Imaging in Planning Surgery and Radiation Therapy and Measuring Response in Patients With Newly Diagnosed Ewing Sarcomadiagnostic0completed
NCT05024253
Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.treatment3completed
NCT00674193
Evaluating Dactinomycin and Vincristine in Young Patients With CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT05116800
Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcomatreatment2withdrawn
NCT06068075
Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARDNo drug interventionsdiagnosticNot Availablerecruiting
NCT00618813
Two Regimens of Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed Localized Ewing Sarcoma Family of TumorstreatmentNot Availablecompleted
NCT01795430
Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing SarcomatreatmentNot Availablewithdrawn
NCT02727387
Protocol for the Treatment of Metastatic Ewing Sarcomatreatment2completed
NCT01962103
Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumorstreatment1 / 2completed
NCT02389244
A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomastreatment2recruiting
NCT02867592
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumorstreatment2active_not_recruiting
NCT03220035
Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)treatment2active_not_recruiting
NCT06659224
The Risk of Acute Myeloid Leukaemia in Patients with Ewing's SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04890093
Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumorstreatment1 / 2recruiting
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)treatment1 / 2recruiting
NCT06566092
Study of Autologous Tumor-Infiltrating Lymphocytes in Pediatric, Adolescent, and Young Adult Participantstreatment1recruiting
NCT02508038
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumorstreatment1suspended
NCT05440786
CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcomatreatment2recruiting
NCT05734066
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcomatreatment1 / 2recruiting
NCT04995003
HER2 Chimeric Antigen Receptor (CAR) T Cells in Combination With Checkpoint Blockade in Patients With Advanced Sarcomatreatment1recruiting
NCT06625190
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumorstreatment1 / 2not_yet_recruiting
NCT06465199
Difluoromethylornithine (DFMO) and AMXT-1501 for Neuroblastoma, CNS Tumors, and Sarcomastreatment1 / 2not_yet_recruiting
NCT05918640
Lurbinectedin in FET-Fused Tumorstreatment1 / 2recruiting
NCT06029218
Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton TherapyNo drug interventionstreatmentNot Availablerecruiting
NCT00617890
A Study to Determine the Activity of Robatumumab (SCH 717454) in Participants With Relapsed Osteosarcoma or Ewing's Sarcoma (MK-7454-002/P04720)treatment2terminated
NCT05182164
Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomastreatment2recruiting
NCT03495921
A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and Temozolomidetreatment3terminated
NCT05302921
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumorstreatment2active_not_recruiting
NCT06451302
Risk Stratification Oriented Treatment of Pediatric Ewing Sarcoma: a Prospective Multicenter Cohort StudytreatmentNot Availableactive_not_recruiting
NCT01286987
Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumorstreatment1completed
NCT04337177
Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumorstreatment1recruiting
NCT04956198
Drug Sensitivity and Mutation ProfilingNo drug interventionsNot AvailableNot Availablecompleted
NCT02536183
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumorstreatment1terminated
NCT02520128
A Study of IMRT in Primary Bone and Soft Tissue SarcomaNo drug interventionstreatmentNot Availablecompleted
NCT02624388
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)supportive_care2terminated
NCT06243588
Identification of Prognostic Factors and Role of Radiotherapy in Patients With Ewing SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00001209
A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumorstreatment1completed
NCT06387485
A Study to Evaluate the Utilization of 3D Printed Models in Pre-Operative PlanningNo drug interventionstreatmentNot Availablerecruiting
NCT04067115
SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patientstreatment1 / 2active_not_recruiting
NCT01661400
Anti-Angiogenic Therapy Post Transplant (ASCR) for Pediatric Solid Tumorstreatment1completed
NCT02945800
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcomatreatment2active_not_recruiting
NCT01610570
Mithramycin for Children and Adults With Solid Tumors or Ewing Sarcomatreatment1 / 2terminated
NCT01969942
A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcomatreatment1withdrawn
NCT02076906
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT04730349
A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancertreatment1 / 2terminated
NCT00520936
A Study of Pemetrexed in Children With Recurrent Cancertreatment2completed
NCT02013336
Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumorstreatment1unknown_status
NCT02982941
Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumorstreatment1completed
NCT00743496
A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and MelanomaNo drug interventionstreatment1completed
NCT03778996
SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcomatreatment2active_not_recruiting
NCT05328258
Use of GnRHa During Chemotherapy for Fertility Protectiontreatment3recruiting
NCT02856048
Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancertreatment2 / 3unknown_status
NCT00464620
Trial of Dasatinib in Advanced Sarcomastreatment2completed
NCT04055220
Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone SarcomastreatmentNot Availablerecruiting
NCT02044120
ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcomatreatment1completed
NCT01882231
Quantitative Imaging Biomarkers of Treatment Response in Osteosarcoma and Ewing SarcomaNo drug interventionsdiagnosticNot Availableterminated
NCT00931931
HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid TumorsNo drug interventionstreatment1completed
NCT03441360
Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS)treatment2completed
NCT00474760
Study Of Anti-IGF-IR CP-751,871 In Patients With Solid Tumorstreatment1completed
NCT02100891
Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumorstreatment2completed
NCT03478462
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcomatreatment1active_not_recruiting
NCT03709680
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumorstreatment1 / 2active_not_recruiting
NCT06340204
Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcomatreatment1recruiting
NCT06564272
A Study of KC1036 in Adolescents With Advanced Ewing SarcomaNo drug interventionstreatment2recruiting
NCT05968768
To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)treatment2recruiting
NCT01807468
Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid TumorsNo drug interventionstreatment2unknown_status
NCT01492569
Acupuncture Point Stimulation for Treatment of Chemotherapy Nausea and VomitingNo drug interventionssupportive_careNot Availablewithdrawn
NCT06156410
Cabozantinib With Ifosfamide in Ewing's Sarcoma and Osteosarcomatreatment1recruiting
NCT03029481
Single Patient Expanded Access to Ganitumab for Metastatic Ewing SarcomaNot AvailableNot Availableno_longer_available
NCT05046314
A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcomatreatment2recruiting
NCT00898755
Collecting and Storing Tissue From Young Patients With CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03245450
Study Evaluating the Safety and Efficacy of Eribulin Mesilate in Combination With Irinotecan Hydrochloride in Children With Refractory or Recurrent Solid Tumorstreatment1 / 2completed
NCT03880123
Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcomatreatment1withdrawn
NCT04433221
Combination Immunotherapy Targeting SarcomasNo drug interventionstreatment1 / 2unknown_status
NCT04897321
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)treatment1recruiting
NCT02581384
Stereotactic Body Radiotherapy (SBRT) for Pulmonary Metastases in Ewing Sarcoma, Rhabdomyosarcoma, and Wilms TumorsNo drug interventionstreatment1 / 2terminated
NCT01780779
Osteosarcoma and Ewing Sarcoma Treatment Response Assessment With Functional MRI Imaging in Children and Young AdultsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03715933
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomastreatment1recruiting
NCT02557854
HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumorstreatment1withdrawn
NCT04129151
Palbociclib + Ganitumab In Ewing Sarcomatreatment2terminated
NCT01625351
A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomastreatment1completed
NCT00840047
Methionine PET/CT Studies In Patients With Cancerdiagnostic2recruiting
NCT00638898
Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumortreatment1active_not_recruiting
NCT02657005
TK216 in Patients With Relapsed or Refractory Ewing Sarcomatreatment1 / 2terminated
NCT03359005
Irinotecan and Temozolomide for Ewing Sarcomatreatment2recruiting
NCT03373097
Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT03604783
Phase 1, First-in-human Study of Oral TP-1287 in Patients With Advanced Solid Tumorstreatment1terminated
NCT00824083
Functional and Clinical Long-Term Outcome of Ewing Sarcoma TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT03458728
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patientstreatment1 / 2terminated
NCT04791228
A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumorstreatment2recruiting
NCT04483778
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adultstreatment1active_not_recruiting
NCT05062707
Early Ageing During Therapy in AYA Cancer PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT04758000
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapseprevention2recruiting
NCT05779670
Adherence to a Personalized Home Exercise Program in Patients With Bone Tumor Undergoing Lower Extremity Salvage SurgeryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03600649
Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomastreatment1active_not_recruiting
NCT03275818
Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcomatreatment2completed
NCT02415816
Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue SarcomasNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT05266196
A Rollover Protocol to Allow for Continued Access to the LSD1 Inhibitor Seclidemstat (SP-2577)treatment1 / 2enrolling_by_invitation
NCT05605522
A Study of [225Ac]-FPI-2059 in Adult Participants With Solid TumoursNo drug interventionstreatment1recruiting
NCT05093322
A Study of Surufatinib in Combination With Gemcitabine in Pediatric, Adolescent, and Young Adult Patients With Recurrent or Refractory Solid Tumorstreatment1 / 2completed
NCT04308330
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignanciestreatment1recruiting
NCT05275426
A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumortreatment2recruiting
NCT03842865
Expanded Access of Vigil in Solid TumorsNo drug interventionsNot AvailableNot Availabletemporarily_not_available
NCT03190174
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancerstreatment1 / 2completed
NCT03356782
Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting SarcomasNo drug interventionstreatment1 / 2unknown_status
NCT02409576
Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomastreatment1 / 2unknown_status
NCT00026780
Eligibility Screening for a NCI Pediatric Oncology Branch Research StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04735289
Dietary Habits, Metabolome, Immune Profile and Microbiota in Patients With Bone SarcomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00186992
Radiation Therapy to Treat Musculoskeletal TumorsNo drug interventionstreatment2active_not_recruiting
NCT06094101
Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)No drug interventionstreatment1 / 2recruiting
NCT01858168
Phase I Study of Olaparib and Temozolomide for Ewings Sarcoma or Rhabdoomyosarcomatreatment1active_not_recruiting
NCT05100368
The Prognostic Value of Serum Biomarkers in Ewing's SarcomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05772312
Quality of Life of Patients With Bone Tumor of the Lower Limbs Treated With Salvage SurgeryNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03618381
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young AdultsNo drug interventionstreatment1recruiting
NCT00180947
Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapsetreatment2unknown_status
NCT01583543
Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcomatreatment2completed
NCT01336803
Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRIdiagnostic2completed
NCT00001564
A Pilot Study of Tumor-Specific Peptide Vaccination and IL-2 With or Without Autologous T Cell Transplantation in Recurrent Pediatric Sarcomastreatment2completed
NCT00568464
Study on VCD/IE in the Patients With Ewing's Sarcoma Family of Tumors (ESFT)treatment2terminated
NCT01313884
Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcomatreatment2terminated
NCT00004853
Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive Chemotherapytreatment1completed
NCT00541411
Phase II Pilot Study of Vincristine, Adriamycin, Actinomycin D, Ifosfamide Combination Chemotherapy in Ewing's SarcomatreatmentNot Availableunknown_status
NCT04671693
A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.No drug interventionspreventionNot Availablerecruiting
NCT02162732
Molecular-Guided Therapy for Childhood CancerNo drug interventionstreatmentNot Availablecompleted
NCT00038142
Vincristine, Doxorubicin, Cyclophosphamide and Dexrazoxane (VACdxr) in High Risk Ewing's Sarcoma Patientstreatment2terminated
NCT02890758
Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803treatment1completed
NCT00001335
New Therapeutic Strategies for Patients With Ewing's Sarcoma Family of Tumors, High Risk Rhabdomyosarcoma, and Neuroblastomatreatment2completed
NCT01331135
Aflac ST0901 CHOANOME - Sirolimus in Solid Tumorstreatment1completed
NCT01734863
Post-operative Radiotherapy in Poor Responders Ewing's Sarcoma PatientsNo drug interventionstreatment3withdrawn
NCT00563680
QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumorstreatment2completed
NCT01061840
Trial of Bi-shRNA-furin and GMCSF Augmented Autologous Tumor Cell Vaccine for Advanced CancerNo drug interventionstreatment1completed
NCT01222767
Study of Zalypsis® (PM00104) in Patients With Unresectable Locally Advanced and/or Metastatic Ewing Family of Tumors (EFT) Progressing After at Least One Prior Line of Chemotherapytreatment2completed
NCT00428272
HGS-ETR2 to Treat Children With Solid Tumorstreatment1terminated
NCT01169584
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patientstreatment1completed
NCT01598454
Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosidestreatment1completed
NCT02511132
A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcomatreatment2completed
NCT02689336
Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumorstreatment2withdrawn
NCT00987636
Study in Localized and Disseminated Ewing Sarcomatreatment3completed
NCT00492141
Aerosol L9-NC and Temozolomide in Ewing's Sarcomatreatment1 / 2completed
NCT00179816
Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumorstreatment1 / 2unknown_status
NCT00001686
Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT00165139
Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomastreatment2completed
NCT02063022
Efficacy of Dose Intensification in Patients With Non-metastatic Ewing Sarcomatreatment3completed
NCT00001566
A Pilot Study of Autologous T-Cell Transplantation With Vaccine Driven Expansion of Anti-Tumor Effectors After Cytoreductive Therapy in Metastatic Pediatric Sarcomastreatment2completed
NCT03442465
Assessment of Healing and Function After Reconstruction Surgery for Bone SarcomasNo drug interventionsNot AvailableNot Availablerecruiting
NCT02736565
Pbi-shRNA™ EWS/FLI1 Type 1 LPX in Subjects With Advanced Ewing's SarcomaNo drug interventionstreatment1completed
NCT01241162
Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcomatreatment1completed
NCT02472392
Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcomatreatment1completed
NCT01674101
Effects of Preoperative Physical Therapy in Patients With Lower Extremity MalignancyNo drug interventionssupportive_careNot Availablecompleted
NCT01696669
Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young AdultsNo drug interventionstreatment2completed
NCT00923650
Informed Consent in Pediatric Cancer TrialsNo drug interventionsNot AvailableNot Availablecompleted
NCT02390843
Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumorstreatment1completed
NCT01505569
Auto Transplant for High Risk or Relapsed Solid or CNS TumorsotherNot Availablecompleted
NCT00503295
Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lungtreatment2completed
NCT01518413
Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumorstreatment1completed
NCT00560235
Study Of CP-751,871 In Patients With Ewing's Sarcoma Family Of Tumorstreatment1 / 2completed
NCT01112800
Markers of Anthracycline-Related Cardiac Muscle InjuryNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03496402
Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO)No drug interventionsotherNot Availablerecruiting
NCT03542097
Assessment of MGMT Promoter Methylation in Advanced Ewing Sarcoma Treated With Temozolomide and IrinotecanNo drug interventionsNot AvailableNot Availablecompleted
NCT03011528
First-line Treatment of Ewing Tumours With Primary Extrapulmonary Dissemination in Patients From 2 to 50 YearsNo drug interventionstreatment2completed
NCT02159443
Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A AntibodyNo drug interventionsNot AvailableNot Availablecompleted