Excitatory Amino Acids

Name
Excitatory Amino Acids
Accession Number
DBCAT000287
Description

Endogenous amino acids released by neurons as excitatory neurotransmitters. Glutamic acid is the most common excitatory neurotransmitter in the brain. Aspartic acid has been regarded as an excitatory transmitter for many years, but the extent of its role as a transmitter is unclear.

Drugs
DrugDrug Description
Aspartic acidAn amino acid commonly found as a component in total parenteral nutrition.
Glutamic acidAn amino acid commonly found as a component in total parenteral nutrition.
KetamineA rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
D-Aspartic AcidThe D-isomer of aspartic acid. [PubChem]
Sparfosic acidSparfosic acid is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at the terminal nitrogen...
Beta-Hydroxyaspartic AcidNot Available
Adenylosuccinic acidNot Available
Aspartate SemialdehydeNot Available
3-Methylglutamic acidNot Available
PCI-27483PCI-27483 has been used in trials studying the treatment of Pancreatic Cancer, Ductal Adrenocarcinoma, and Exocrine Pancreatic Cancer.
N-Carbamoylaspartic acidAn amino acid commonly found as a component in total parenteral nutrition.
Arginine aspartateAn ingredient in products indicated to treat exhaustion during stress, endurance sports, or in the elderly.
Drugs & Drug Targets
DrugTargetType
Aspartic acidCalcium-binding mitochondrial carrier protein Aralar2target
Aspartic acidAspartate aminotransferase, cytoplasmictarget
Aspartic acidAspartoacylasetarget
Aspartic acidAsparagine synthetase [glutamine-hydrolyzing]target
Aspartic acidArgininosuccinate synthasetarget
Aspartic acidAminoacylase-1target
Aspartic acidAspartate aminotransferase, mitochondrialtarget
Aspartic acidAspartate--tRNA ligase, cytoplasmictarget
Aspartic acidCalcium-binding mitochondrial carrier protein Aralar1target
Aspartic acidAspartyl/asparaginyl beta-hydroxylasetarget
Aspartic acidMultifunctional protein ADE2target
Aspartic acidAdenylosuccinate synthetase isozyme 2target
Aspartic acidExcitatory amino acid transporter 3target
Aspartic acidArgininosuccinate synthetase, isoform CRA_atarget
Aspartic acidAspartate--tRNA ligase, mitochondrialtarget
Aspartic acidIsoaspartyl peptidase/L-asparaginasetarget
Aspartic acidRibonuclease pancreatictarget
Aspartic acidLysozyme Ctarget
Aspartic acidMonocarboxylate transporter 10transporter
Aspartic acidCAD proteinenzyme
Aspartic acidAdenylosuccinate Synthetasestarget
Glutamic acidGlutamate dehydrogenase 1, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, kainate 1target
Glutamic acidGlutamate receptor 1target
Glutamic acidGlutamate--cysteine ligase regulatory subunittarget
Glutamic acidGlutamate carboxypeptidase 2target
Glutamic acidGlutamate decarboxylase 2target
Glutamic acidGlutamate decarboxylase 1target
Glutamic acidFormimidoyltransferase-cyclodeaminasetarget
Glutamic acidGlutamate receptor 2target
Glutamic acidGlutamate receptor 3target
Glutamic acidGlutamate receptor 4target
Glutamic acidDelta-1-pyrroline-5-carboxylate synthasetarget
Glutamic acidGlutamate receptor ionotropic, kainate 2target
Glutamic acidGlutamate receptor ionotropic, kainate 3target
Glutamic acidMetabotropic glutamate receptor 1target
Glutamic acidMetabotropic glutamate receptor 4target
Glutamic acidGlutamate receptor ionotropic, kainate 4target
Glutamic acidGlutamate receptor ionotropic, kainate 5target
Glutamic acidMetabotropic glutamate receptor 7target
Glutamic acidMetabotropic glutamate receptor 8target
Glutamic acidExcitatory amino acid transporter 5target
Glutamic acid5-oxoprolinasetarget
Glutamic acidPhosphoribosylformylglycinamidine synthasetarget
Glutamic acidBranched-chain-amino-acid aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Dtarget
Glutamic acidGlutaminase kidney isoform, mitochondrialtarget
Glutamic acidAspartate aminotransferase, mitochondrialtarget
Glutamic acidBifunctional glutamate/proline--tRNA ligasetarget
Glutamic acidAsparagine synthetase [glutamine-hydrolyzing]target
Glutamic acidGlutamine synthetasetarget
Glutamic acidAspartate aminotransferase, cytoplasmictarget
Glutamic acidTyrosine aminotransferasetarget
Glutamic acidAlanine aminotransferase 1target
Glutamic acidVitamin K-dependent gamma-carboxylasetarget
Glutamic acidExcitatory amino acid transporter 1target
Glutamic acidExcitatory amino acid transporter 2target
Glutamic acidExcitatory amino acid transporter 3target
Glutamic acidGlutamate--cysteine ligase catalytic subunittarget
Glutamic acidExcitatory amino acid transporter 4target
Glutamic acidGlutamate dehydrogenase 2, mitochondrialtarget
Glutamic acidGMP synthase [glutamine-hydrolyzing]target
Glutamic acidBranched-chain-amino-acid aminotransferase, cytosolictarget
Glutamic acid4-aminobutyrate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 1target
Glutamic acidFolylpolyglutamate synthase, mitochondrialtarget
Glutamic acidGlutamyl aminopeptidasetarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Atarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Btarget
Glutamic acidGlutamate receptor ionotropic, NMDA 2Ctarget
Glutamic acidAspartate aminotransferasetarget
Glutamic acidProbable glutamate--tRNA ligase, mitochondrialtarget
Glutamic acidGlutamine-dependent NAD(+) synthetasetarget
Glutamic acidN-acetylglutamate synthase, mitochondrialtarget
Glutamic acidKynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget
Glutamic acidGlutamate receptor ionotropic, NMDA 3Atarget
Glutamic acidAlanine aminotransferase 2target
Glutamic acidAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
Glutamic acidGlutaminase liver isoform, mitochondrialtarget
Glutamic acidAspartyl aminopeptidasetarget
Glutamic acidCystine/glutamate transportertarget
Glutamic acidCarboxypeptidase Qtarget
Glutamic acidPhosphoserine aminotransferasetarget
Glutamic acidMonocarboxylate transporter 10transporter
Glutamic acidMonocarboxylate transporter 1transporter
Glutamic acidMitochondrial glutamate carrier 2transporter
Glutamic acidMitochondrial glutamate carrier 1transporter
KetamineGlutamate receptor ionotropic, NMDA 3Atarget
KetamineNeurokinin 1 receptortarget
KetamineCytochrome P450 2B6enzyme
KetamineCytochrome P450 2C9enzyme
KetamineCytochrome P450 3A4enzyme
KetamineDopamine D2 receptortarget
KetamineProstaglandin G/H synthase 1enzyme
KetamineCytochrome P450 2C8enzyme
KetamineDelta-type opioid receptortarget
KetamineSodium-dependent noradrenaline transportertarget
KetamineKappa-type opioid receptortarget
KetamineMu-type opioid receptortarget
KetamineMuscarinic acetylcholine receptortarget
Ketamine5-hydroxytryptamine receptor 2target
Ketamine5-hydroxytryptamine receptor 1target
Ketamine5-hydroxytryptamine receptor 3Atarget
KetamineAlpha-7 nicotinic cholinergic receptor subunittarget
KetamineCholinesterasetarget
KetamineNitric oxide synthase, braintarget
D-Aspartic AcidThermolysintarget
D-Aspartic AcidL-asparaginasetarget
Sparfosic acidAspartate carbamoyltransferase catalytic chaintarget
Sparfosic acidCAD proteintarget
Beta-Hydroxyaspartic AcidBeta-lactamase TEMtarget
Adenylosuccinic acidAdenylosuccinate synthetase isozyme 1target
Aspartate SemialdehydeAspartate-semialdehyde dehydrogenasetarget
N-Carbamoylaspartic acidDihydroorotasetarget