High Grade Glioma: Glioblastoma (GBM) (DBCOND0052371)

Identifiers

Synonyms
Glioblastoma / Glioblastomas / Glioblastoma (GBM) / Glioblastomas (GBM) / GBM / Glioblastoma (morphologic abnormality) / Glioblastoma multiforme / Glioblastoma multiforme (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Carmustine
An alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
Irinotecan
A topoisomerase inhibitor used to treat metastatic carcinoma of the colon or rectum and pancreatic adenocarcinoma.
Temozolomide
An alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04523688
Vaccination with Autologous Dendritic Cells Loaded with Autologous Tumour Homogenate in Glioblastomatreatment2recruiting
NCT04559230
Sacituzumab Govitecan in Recurrent Glioblastomatreatment2recruiting
NCT04566393
Expanded Access to Ulixertinib (BVD-523) in Patients with Advanced MAPK Pathway-Altered MalignanciesNot AvailableNot Availableavailable
NCT04699773
LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)No drug interventionstreatmentNot Availablerecruiting
NCT04730869
Metabolic Therapy Program In Conjunction With Standard Treatment For GlioblastomaNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT04817254
Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcomatreatment2recruiting
NCT05099003
A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)treatment1 / 2recruiting
NCT05187624
A Study Evaluating the Safety, Pharmacokinetic and Anti-tumor Activity of RO7428731 in Participants With GlioblastomaNo drug interventionstreatment1recruiting
NCT05271240
Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBMtreatment3recruiting
NCT05342883
GammaTile and Stupp in Newly Diagnosed GBMNo drug interventionstreatment4recruiting
NCT05607407
Methimazole in Patients With Progressive Glioblastomatreatment2recruiting
NCT05773664
Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients with Glioblastomatreatment1withdrawn
NCT05839379
Targeted Pediatric High-Grade Glioma TherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05843253
Study of Ribociclib and Everolimus in HGG and DIPGtreatment2recruiting
NCT05900908
Post-operative Adjuvant Therapy w/wo GammaTile + Systemic TherapyNo drug interventionstreatment4not_yet_recruiting
NCT05902169
Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBMtreatment3recruiting
NCT05954858
Surgical Tissue Flap to Bypass the Blood Brain Barrier in GlioblastomaNo drug interventionstreatmentNot Availablerecruiting
NCT05979064
Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)No drug interventionstreatmentNot Availablerecruiting
NCT06061809
N-803 and PD-L1 t-haNK Combined With Bevacizumab for Recurrent or Progressive Glioblastomatreatment2recruiting
NCT06404034
Expanded Access to Gallium Maltolate (GaM)Not AvailableNot Availableavailable
NCT06613841
Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of GlioblastomaNo drug interventionsdiagnostic0not_yet_recruiting
NCT06614855
A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant GliomaNo drug interventionstreatment1not_yet_recruiting
NCT06600399
Correlation Between Prostate-specific Membrane Antigen Positron Emission Tomography and Arterial Spin Labeling Perfusion Imaging in GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02871843
RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic Gliomastreatment1completed
NCT03223103
Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastomatreatment1active_not_recruiting
NCT06090903
Magnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable GlioblastomaNo drug interventionsscreeningNot Availablerecruiting
NCT04221503
Niraparib/TTFields in GBMtreatment2active_not_recruiting
NCT02599090
Phase II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcomatreatment2withdrawn
NCT01609790
Bevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain Tumorstreatment2completed
NCT04209790
Neoadjuvant Chemoradiation for Resectable Glioblastomatreatment2recruiting
NCT02942264
Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastomatreatment1 / 2completed
NCT04047264
Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System MalignanciesNo drug interventionsbasic_scienceNot Availablerecruiting
NCT05664464
Glutamate Inhibitors in Glioblastomatreatment1 / 2recruiting
NCT05326464
Tofacitinib in Recurrent GBM Patientstreatment3recruiting
NCT04998864
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption in GBM PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02478164
Trial of Ponatinib in Patients With Bevacizumab-Refractory Glioblastomatreatment2completed
NCT05871021
Protective VEGF Inhibition for Isotoxic Dose Escalation in GlioblastomaNo drug interventionstreatment2recruiting
NCT06480721
FET-PET-Guided Management of Pseudoprogression in GlioblastomaNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT00689221
Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Statustreatment3completed
NCT00100802
Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomastreatment2completed
NCT05629702
ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoidstreatment2recruiting
NCT01434602
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomastreatment1 / 2completed
NCT03213002
Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBMtreatment1 / 2recruiting
NCT05140902
Accurate DCE-MRI Measurement of Glioblastoma Using Point-of-care Portable Perfusion PhantomNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT04741984
Monocyte Antigen Carrier Cells for Newly Diagnosed GBMtreatment1withdrawn
NCT01156584
A Study of a Retroviral Replicating Vector Combined With a Prodrug Administered to Patients With Recurrent Malignant Gliomatreatment1completed
NCT02473484
Search of Protein Biomarkers in Order to Achieve a Molecular Classification of GliomasNo drug interventionsNot AvailableNot Availablecompleted
NCT02725684
Using Genomic Analysis to Guide Individual Treatment in GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT03452579
Nivolumab Plus Standard Dose Bevacizumab Versus Nivolumab Plus Low Dose Bevacizumab in GBMtreatment2active_not_recruiting
NCT04397679
Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT04478279
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT03603379
Doxorubicin-loaded Anti-EGFR-immunoliposomes (C225-ILs-dox) in High-grade GliomasNo drug interventionsbasic_science1completed
NCT02342379
TH-302 in Combination With Bevacizumab for Glioblastomatreatment2completed
NCT00813943
Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Statustreatment2completed
NCT00575887
Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Gliomatreatment2completed
NCT05768087
Escalated Dose Proton Therapy Within the Multimodality Treatment of Glioblastoma PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT02648633
Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastomatreatment1terminated
NCT01851733
MRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma Multiformetreatment1completed
NCT04417933
Tumor Electric Fields Treatment System for GlioblastomaNo drug interventionsdevice_feasibility0unknown_status
NCT03463733
Hydroxy-urea and Temozolomide in Patients With a Recurrent Malignant Brain Tumor (Glioblastoma)treatment1unknown_status
NCT00613054
Ph I Zactima + Imatinib Mesylate & Hydroxyurea for Pts w Recurrent Malignant Gliomatreatment1completed
NCT00080054
A Study of Motexafin Gadolinium and Temozolomide for the Treatment of Malignant Gliomastreatment1completed
NCT02254954
Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastomatreatment1terminated
NCT01817751
Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Gliomatreatment2completed
NCT03705351
Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBMtreatment1terminated
NCT00087451
Safety Study of AP23573 in Patients With Progressive or Recurrent Glioma (8669-023)(COMPLETED)treatment1completed
NCT00612651
PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomastreatment1completed
NCT04474353
Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT00115453
Boron Neutron Capture Therapy (BNCT) as Treatment of GlioblastomaNo drug interventionstreatment1 / 2terminated
NCT00165477
Study of Lenalidomide and XRT in Patients With Newly Diagnosed Glioblastoma Multiformetreatment2completed
NCT04552977
A Trail of Fluzoparil in Combination With Temozolomide in Patients With Recurrent Glioblastomatreatment2unknown_status
NCT01721577
Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant Astrocytomastreatment1 / 2terminated
NCT04555577
Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or Gliosarcomatreatment1recruiting
NCT03636477
A Study of Ad-RTS-hIL-12 With Veledimex in Combination With Nivolumab in Subjects With Glioblastoma; a Substudy to ATI001-102treatment1completed
NCT02410577
89Zr-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients With Glioblastoma MultiformeNo drug interventionsdiagnosticNot Availablecompleted
NCT01813877
Response Monitoring Trial in Patients With Suspected Recurrence of GlioblastomaNo drug interventionsdiagnosticNot Availablecompleted
NCT04545177
Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain TissueNo drug interventionsdevice_feasibilityNot Availableactive_not_recruiting
NCT01100177
Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patientstreatment2completed
NCT04801147
Immunotherapy With Autologous Tumor Lysate-Loaded Dendritic Cells In Patients With Newly Diagnosed Glioblastoma Multiformetreatment1 / 2unknown_status
NCT04599647
EAP for the Treatment of Glioblastoma With PVSRIPONot AvailableNot Availableno_longer_available
NCT02866747
A Study Evaluating the Association of Hypofractionated Stereotactic Radiation Therapy and Durvalumab for Patients With Recurrent Glioblastomatreatment1 / 2active_not_recruiting
NCT01465347
Safety and Efficacy of Trans Sodium Crocetinate (TSC) With Radiation and Temozolomide in Newly Diagnosed Glioblastomatreatment1 / 2completed
NCT03392545
Combination of Immunization and Radiotherapy for Malignant Gliomas (InSituVac1)No drug interventionstreatment1unknown_status
NCT05917145
Clinical Trial of the ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Recurrent Brain TumorsNo drug interventionstreatment1recruiting
NCT04359745
Improving Treatment of Glioblastoma: Distinguishing Progression From PseudoprogressionNo drug interventionsNot AvailableNot Availablerecruiting
NCT02457845
HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumorstreatment1completed
NCT01931098
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumabtreatment2completed
NCT00616005
Ph. II Treatment of Adults w Primary Malignant Glioma w Irinotecan + Temozolomidetreatment2completed
NCT04243005
Supramarginal Resection in GlioblastomaNo drug interventionstreatmentNot Availablerecruiting
NCT06113705
Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study.No drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01516905
PET/CT Imaging of Malignant Brain Tumors With 124I-NM404No drug interventionsNot AvailableNot Availablecompleted
NCT02590497
Correlation Between the Genetic and Neuroimaging Signatures in Newly Diagnosed Glioblastoma Patients Before SurgerydiagnosticNot Availablewithdrawn
NCT01598597
An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)No drug interventionsNot AvailableNot Availablecompleted
NCT01111097
Study of the Safety and Efficacy of Dichloroacetate (DCA) in Glioblastoma and Other Recurrent Brain Tumorstreatment1completed
NCT02715297
Adjuvant Stereotactic Fractionated Radiotherapy to the Resection Cavity in Recurrent GlioblastomaNo drug interventionstreatment2unknown_status
NCT04829097
Neoadjuvant Temozolomide Combined With Simultaneous IMRT for Treatment of Glioblastomatreatment3unknown_status
NCT02359097
Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With GlioblastomadiagnosticNot Availablecompleted
NCT00238797
A Phase II Exploratory, Multicentre, Open-label, Non-comparative Study of ZD1839 (Iressa) and Radiotherapy in the Treatment of Patients With Glioblastoma Multiformetreatment2completed
NCT03491683
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)treatment1 / 2active_not_recruiting
NCT03877861
Validation of Readiband™ Actigraph and Associated Sleep/Wake Classification AlgorithmsNo drug interventionsNot AvailableNot Availablecompleted
NCT00200161
Temozolomide & RT Followed by Dose Dense vs Temozolomide & Retinoic Acid in Pts w/Glioblastomatreatment2completed
NCT00431561
Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Gliomatreatment2completed
NCT01632228
A Study of Onartuzumab (MetMAb) in Combination With Bevacizumab Compared to Bevacizumab Alone or Onartuzumab Monotherapy in Participants With Recurrent Glioblastomatreatment2completed
NCT02466828
qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia.diagnostic0completed
NCT00624728
Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP)No drug interventionsdiagnostic1 / 2completed
NCT02287428
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBMtreatment1recruiting
NCT01905228
A Phase 1 Trial of CBL0137 in Patients With Metastatic or Unresectable Advanced Solid NeoplasmNo drug interventionstreatment1completed
NCT06512311
Personalized Targeted Glioblastoma Therapies by ex Vivo Drug ScreeningNo drug interventionsotherNot Availablerecruiting
NCT01535911
Pilot Study of a Metabolic Nutritional Therapy for the Management of Primary Brain TumorsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00250211
Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and TemozolomideNo drug interventionstreatment1 / 2completed
NCT01491893
PVSRIPO for Recurrent Glioblastoma (GBM)treatment1completed
NCT00906893
Evaluation of [18F]-FMISO for Non Operated GlioblastomaNo drug interventionshealth_services_research2completed
NCT03593993
A Biospecimen Collection Study in BRAF-V600E Mutated Recurrent GliomasNo drug interventionsNot AvailableNot Availableterminated
NCT06496971
A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patientstreatment3not_yet_recruiting
NCT01846871
Tivozanib for Recurrent Glioblastomatreatment2completed
NCT03548571
Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapytreatment2 / 3recruiting
NCT05735171
Supramarginal Resection in Glioblastoma Guided by Artificial IntelligenceNo drug interventionstreatmentNot Availablerecruiting
NCT01478178
Safety Study of VAL-083 in Patients With Recurrent Malignant Gliomatreatment1 / 2completed
NCT02743078
Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastomatreatment2terminated
NCT03688178
DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumabtreatment2active_not_recruiting
NCT05439278
Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly Glioblastomatreatment3not_yet_recruiting
NCT02770378
A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastomatreatment1 / 2completed
NCT06058988
Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancertreatment2recruiting
NCT03137888
Spectroscopic MRI-Guided Radiation Therapy Planning in Glioblastomatreatment2active_not_recruiting
NCT03293888
Spectral Analysis Probe to Identify Glioblastoma CellsNo drug interventionsNot AvailableNot Availableterminated
NCT01105988
Evaluating Tumor Pseudoprogression With FLT-PET and MRINo drug interventionsdiagnostic0terminated
NCT03926507
F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing SurgeryNo drug interventionsdiagnosticNot Availablecompleted
NCT04135807
Implantable Microdevice In Primary Brain TumorsNo drug interventionsdiagnostic0recruiting
NCT06551909
Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2)No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04614909
Study of Pamiparib in Newly Diagnosed and rGBMtreatment0recruiting
NCT03787056
Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer PatientsNo drug interventionsdiagnosticNot Availablerecruiting
NCT04574856
Multiparametric MR-Guided High Dose Adaptive Radiotherapy With Concurrent Temozolomide in Patients With Newly Diagnosed Glioblastomatreatment2recruiting
NCT01957956
Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastomatreatment0completed
NCT01403285
Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastomatreatment1terminated
NCT05756985
Improving Understanding of Glioblastoma Through Preservation of Biologically Active Brain TissueNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00295815
Enzastaurin Versus Lomustine in Glioblastomatreatment3completed
NCT04657315
Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma PatientsNo drug interventionstreatment1 / 2completed
NCT05131815
The BurnAlong Pilot Study for Adolescent and Young Adult Cancer SurvivorsNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT02893137
Enhancing Optune Therapy With Targeted CraniectomyNo drug interventionstreatment1completed
NCT02841332
Multimodal Imaging Analysis During Treatment With Bevacizumab in Patients With Recurrent Glioblastomabasic_scienceNot Availableterminated
NCT06385132
Psychological and Psychiatric prOfile in Glioblastoma and Head and Neck CancerNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02919332
Delayed 18F-FDG PET/CT in Improving Visualization of Brain Tumors in Patients With GlioblastomaNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03732352
18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients With EGFR Activated Recurrent Glioblastomatreatment2active_not_recruiting
NCT00068952
Study of IV Edotecarin Vs Temozolomide or Carmustine (BCNU) or Lomustine (CCNU) in Patients With Glioblastoma Multiformetreatment3completed
NCT03233152
Intra-tumoral Ipilimumab Plus Intravenous Nivolumab Following the Resection of Recurrent Glioblastomatreatment1unknown_status
NCT04959500
Newly Diagnosed Glioblastomatreatment2unknown_status
NCT05054400
Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MRtreatment0withdrawn
NCT00088400
Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumorstreatment3completed
NCT00335075
Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644)treatment3completed
NCT04219475
Predicting Response Patterns to Treatment in Glioblastoma (GBM) PatientsNo drug interventionsNot AvailableNot Availablesuspended
NCT04469075
Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fieldstreatment2recruiting
NCT02678975
Disulfiram in Recurrent Glioblastomatreatment2 / 3completed
NCT06329570
Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)treatment1 / 2not_yet_recruiting
NCT00671970
Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG)treatment2completed
NCT01520870
Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.treatment2completed
NCT04313842
A Explorative Study to Evaluate the Clinical Feasibility of AVATAMEDNo drug interventionsNot AvailableNot Availableunknown_status
NCT03951142
Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Studydiagnostic2enrolling_by_invitation
NCT03869242
NovoTTF-200A Together With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GBMNo drug interventionstreatmentNot Availableunknown_status
NCT03250299
Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastomatreatment1terminated
NCT04716699
Systemic and Local Levels of Lidocaine During Surgery for the Removal of Glioblastomabasic_science1completed
NCT01854099
Peptide Vaccine for Glioblastoma Against Cytomegalovirus Antigenstreatment1withdrawn
NCT03861299
The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.No drug interventionstreatmentNot Availablerecruiting
NCT04047706
Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT02343406
Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomastreatment2completed
NCT04874506
MBM-02 (Tempol) for the Treatment of Glioblastoma Multiforme (GBM)treatment2unknown_status
NCT03341806
Avelumab With Laser Interstitial Therapy for Recurrent Glioblastomatreatment1completed
NCT01507506
Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of GlioblastomaNo drug interventionstreatment3terminated
NCT02010606
Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastomatreatment1completed
NCT03197506
Pembrolizumab and Standard Therapy in Treating Patients With Glioblastomatreatment2suspended
NCT03278249
Feasibility Study of Modified Atkins Ketogenic Diet in the Treatment of Newly Diagnosed Malignant GliomaNo drug interventionstreatmentNot Availableunknown_status
NCT03980249
Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cellstreatment0withdrawn
NCT04485949
A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastomatreatment2active_not_recruiting
NCT05236036
Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastomatreatment1recruiting
NCT03050736
Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expressiontreatment2active_not_recruiting
NCT00354913
Imatinib Mesylate and Hydroxyurea in Treating Patients With Recurrent or Progressive Meningiomatreatment2completed
NCT03734913
A Phase 1 Study of ZSP1602 in Participants With Advanced Solid TumorsNo drug interventionstreatment1unknown_status
NCT01189513
SCH-900105 in Recurrent GlioblastomaNo drug interventionstreatment1withdrawn
NCT03246113
Tolerability of Cannabis in Patients Receiving Concurrent Chemoradiation for Glioblastomatreatment1terminated
NCT03477513
Personalized Radiation Therapy for GBMNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT06418113
Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With GlioblastomaNo drug interventionstreatment1recruiting
NCT05551013
Treatment of Recurrent GBM With APG-157 Via Expanded AccessNot AvailableNot Availableno_longer_available
NCT04937413
The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluationbasic_science0completed
NCT05375318
BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological LevelsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05565118
Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of ProgressionNo drug interventionstreatment1recruiting
NCT01351519
A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumorstreatment2terminated
NCT00780819
Borderzone SamplingNo drug interventionsdiagnosticNot Availablecompleted
NCT01083719
A Comparison of FDG-PET Versus MRI Based Target Volume Delineation in Glioblastoma and the Role of FDG-PET/CT in the Alteration of MRI Based Target Volumes.No drug interventionstreatment2unknown_status
NCT06105619
A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).treatment2 / 3active_not_recruiting
NCT02585219
Pilot Viability of 11C-MET-PET as a Post-surgery Baseline Scan in High-grade GliomasNo drug interventionsNot AvailableNot Availableunknown_status
NCT01493219
Biomarkers for Prognosis of Glioblastoma (GBM)No drug interventionsNot AvailableNot Availablecompleted
NCT05095441
A Clinical Study of Intratumoral MVR-C5252 (C5252) in Patients With Recurrent or Progressive GlioblastomaNo drug interventionstreatment1not_yet_recruiting
NCT05772741
Grafts of GSCs Into Brain Organoids for Testing Anti-invasion DrugsNo drug interventionsbasic_scienceNot Availablerecruiting
NCT01502241
Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderlytreatment3completed
NCT02432417
The Addition of Chloroquine to Chemoradiation for Glioblastoma,treatment2withdrawn
NCT05635734
Azeliragon and Chemoradiotherapy in Newly Diagnosed Glioblastomatreatment1 / 2recruiting
NCT01653834
Feasibility of Lymphocyte Reinfusion in Newly Diagnosed High Grade GliomasNo drug interventionstreatmentNot Availablecompleted
NCT02611024
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumorstreatment1 / 2recruiting
NCT02345824
Early-Phase Study to Assess Inhibitor Ribociclib in Patients With Recurrent Glioblastoma or Anaplastic Gliomatreatment1unknown_status
NCT01421524
Study of CC-122 to Evaluate the Safety, Tolerability, and Effectiveness for Patients With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myelomatreatment1completed
NCT00402116
Phase 1/2 Study of Enzastaurin in Newly Diagnosed Glioblastoma Multiforme (GBM) and Gliosarcoma (GS) Patientstreatment1 / 2completed
NCT01975116
p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumorstreatment1completed
NCT04446416
Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM PatientstreatmentNot Availablecompleted
NCT00884416
Sorafenib in Newly Diagnosed High Grade Gliomatreatment1completed
NCT04868396
Patient-derived Glioma Stem Cell OrganoidsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02238496
Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomastreatment1completed
NCT05106296
Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancertreatment1recruiting
NCT04479696
Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain TumorsNo drug interventionssupportive_careNot Availablerecruiting
NCT01454596
CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIIItreatment1 / 2completed
NCT00132158
ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumorstreatment1completed
NCT04604158
Evaluating the Effect of a Mobile Audio Companion (Elly) to Reduce Anxiety in Cancer PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT02047058
Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological CharacteristicsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02684058
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumorstreatment2completed
NCT03939858
Bioenergetic Profiling and Cognition in GBM PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT01383135
Biodistribution and Safety of the PET Probes [18F]FPRGD2 and [18F]FPPRGD2No drug interventionsdiagnostic0completed
NCT02520635
Supra-early Post-Surgery Chemotherapy in the Treatment on GBM PatientsNot AvailableNot Availableunknown_status
NCT02129335
Stress, Exercise Behavior and Survival in Patients With Newly Diagnosed Glioblastoma and in a Close PartnerNo drug interventionsNot AvailableNot Availableterminated
NCT02899663
MRI Detection of Microbleeds in Glioma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00345163
A Study to Evaluate Bevacizumab Alone or in Combination With Irinotecan for Treatment of Glioblastoma Multiforme (BRAIN)treatment2completed
NCT03287063
Study Using Genomic, Histologic and Radiomic Analysis to Evaluate Regional Tumor Heterogeneity in Patients Undergoing Surgery for Newly Diagnosed GlioblastomaNo drug interventionsNot AvailableNot Availablesuspended
NCT06556563
EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastomatreatment3not_yet_recruiting
NCT05304663
Safety and Efficacy of Different Administration Sequences of L19TNF With Lomustine in Glioblastoma at First Progressiontreatment1withdrawn
NCT06524063
Targeted Survivin DC Cell Injection for the Treatment of GBMNo drug interventionstreatment1not_yet_recruiting
NCT02664363
EGFRvIII CAR T Cells for Newly-Diagnosed WHO Grade IV Malignant GliomaNo drug interventionstreatment1terminated
NCT02800486
Super Selective Intra-arterial Repeated Infusion of Cetuximab (Erbitux) With Reirradiation for Treatment of Relapsed/Refractory GBM, AA, and AOAtreatment2recruiting
NCT03506139
Biologically-based Target Volumes to Treat Newly Diagnosed GlioblastomaNo drug interventionstreatment2withdrawn
NCT04225039
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastomatreatment2active_not_recruiting
NCT00612339
Avastin in Combination With Temozolomide for Unresectable or Multifocal GBMs and Gliosarcomastreatment2completed
NCT06477939
Study of Adding or Not Liposomal Transcrocetin (L-TC) With Concomitant HypoFractionated Radiation ThErapy and TEmozolomide in Newly Diagnosed GLioblastoma (GBM) Patientstreatment3not_yet_recruiting
NCT05296122
Safety and Feasibility of MR-guided Laser Thermal Ablation of Brain LesionsNo drug interventionsdevice_feasibilityNot Availableactive_not_recruiting
NCT03927222
Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Gliomatreatment2terminated
NCT00365222
Phase II Study of Temozolomide in Newly Diagnosed Glioblastomatreatment2terminated
NCT00525525
Study of Bevacizumab Plus Temodar and Tarceva in Patients With Glioblastoma or Gliosarcomatreatment2completed
NCT04541225
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid TumorsNo drug interventionstreatment1terminated
NCT03297125
Assessment of Optune Therapy for Patients With Newly Diagnosed Glioblastoma Using Advanced MRINo drug interventionsNot AvailableNot Availablerecruiting
NCT02149225
GAPVAC Phase I Trial in Newly Diagnosed Glioblastoma Patientstreatment1completed
NCT00643825
Prolonged Adjuvant Temozolomide vs "Stop & Go" in Glioblastoma Patientstreatment2unknown_status
NCT00611325
Phase II Avastin + Bortezomib for Patients With Recurrent Malignant Gliomatreatment2completed
NCT01044225
Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastomatreatment2terminated
NCT02904525
Glioblastoma: Validation and Comparison Between Primary Tumor and Its Murine ModelNo drug interventionsdiagnosticNot Availableunknown_status
NCT06102525
A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Glioblastomatreatment1 / 2recruiting
NCT02490930
A Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade Gliomaother0completed
NCT01903330
ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiformetreatment2unknown_status
NCT05353530
Phase I Study of IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult Glioblastoma (IMPACT)No drug interventionstreatment1recruiting
NCT02206230
Trial of Hypofractionated Radiation Therapy for GlioblastomaNo drug interventionstreatment2completed
NCT03452930
Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastomatreatment1completed
NCT03389230
Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV GliomaNo drug interventionstreatment1active_not_recruiting
NCT05463848
Surgical Pembro +/- Olaparib w TMZ for rGBMtreatment2recruiting
NCT04280848
Anticancer Therapeutic Vaccination Using Telomerase-derived Universal Cancer Peptides in Glioblastomatreatment2active_not_recruiting
NCT00392548
URINARY VEGF Levels in GBM Patients on Radiation Treatment ProtocolNo drug interventionsNot AvailableNot Availableunknown_status
NCT02902757
FDG PET/CT in Monitoring Very Early Therapy Response in Patients With GlioblastomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00973557
The Effect of Monoclonal Vascular Endothelial Growth Factor (VEGF) Antibody (Bevacizumab) on Pituitary FunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT02629757
A Study on β-elemene as Maintain Treatment for Newly Diagnosed Malignant GliomasNo drug interventionstreatment3unknown_status
NCT03797326
Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)treatment2active_not_recruiting
NCT02394626
Surgery for Recurrent GlioblastomaNo drug interventionstreatment2recruiting
NCT02666066
Radiomics for Prediction of Survival in GBMNo drug interventionsNot AvailableNot Availablecompleted
NCT04732065
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumorstreatment1recruiting
NCT02394665
Dose Escalated MRSI Guided Radiation Therapy in Glioblastomatreatment2terminated
NCT03452774
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT04105374
Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastomatreatment2 / 3withdrawn
NCT04119674
Pilot Study of Anlotinib With STUPP Regimen for Patients With Newly Diagnosed Glioblastomatreatment1 / 2completed
NCT01522820
Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumorstreatment1completed
NCT04583020
Neoadjuvant PD-1 in Newly Diagnosed Glioblastomatreatment2unknown_status
NCT02176720
Response Monitoring Trial in Patients With Suspected Recurrence of GlioblastomaNo drug interventionsdiagnostic1terminated
NCT01291420
Dendritic Cell Vaccination for Patients With Solid TumorsNo drug interventionstreatment1 / 2completed
NCT06439420
CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot TrialNo drug interventionstreatment2recruiting
NCT02152982
Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiformetreatment2 / 3active_not_recruiting
NCT01380782
BIBF 1120 for Recurrent High-Grade Gliomastreatment2completed
NCT05063682
The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in PatientsNo drug interventionstreatment1unknown_status
NCT02025231
Image Guided Reirradiation of High-grade GliomaNo drug interventionstreatment1 / 2terminated
NCT03481231
In Situ Immune Parameters and Their Prognostic Role on the Survival of Patients With GlioblastomaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04623931
Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomastreatment2recruiting
NCT01011231
Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Imaging (MRI) Spectroscopy for Recurrent GliomaNo drug interventionstreatment2terminated
NCT03539731
[18F]DASA-23 and PET Scan in Evaluating Pyruvate Kinase M2 Expression in Patients With Intracranial Tumors or Recurrent Glioblastoma and Healthy VolunteersNo drug interventionsdiagnostic1terminated
NCT01898273
Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastomadiagnostic2terminated
NCT03251027
Intensity-Modulated Stereotactic Radiation Therapy in Treating Patients With Grade II-IV GliomaNo drug interventionstreatmentNot Availablerecruiting
NCT06283927
The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)Not AvailableNot Availablerecruiting
NCT01112527
PF-00299804 in Adult Patients With Relapsed/Recurrent Glioblastomatreatment2completed
NCT00807027
Clinical Trial to Assess the Efficacy and Safety of 'INNOCELL Immuncell-LC' With Temozolomide in Newly Diagnosed Glioblastoma of KoreaNo drug interventionstreatment3completed
NCT00723827
Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)Not AvailableNot Availablecompleted
NCT01443676
Avastin Plus Radiotherapy in Elderly Patients With Glioblastomatreatment2completed
NCT01782976
Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)treatment2withdrawn
NCT05695976
GRETeL: Tumor Response to Standard Radiotherapy and TMZ Patients With GBMNo drug interventionsNot AvailableNot Availablerecruiting
NCT04319276
Oral Gallium Maltolate for the Treatment of Relapsed and Refractory Glioblastomatreatment1recruiting
NCT05095376
Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastomatreatment3recruiting
NCT01954576
NovoTTF Therapy in Treating Patients With Recurrent Glioblastoma MultiformeNo drug interventionstreatmentNot Availableterminated
NCT06129760
Glioblastoma Remote Monitoring and Care - Research ProtocolNo drug interventionstreatmentNot Availablerecruiting
NCT03616860
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption for Treatment of GliomaNo drug interventionstreatmentNot Availablecompleted
NCT01240460
Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resectiontreatment1completed
NCT00895960
Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastomatreatment1terminated
NCT03176160
LITT Palliative Treatment for Patients With Malignant GliomasNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03778294
18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapytreatment2completed
NCT03422094
Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastomatreatment1terminated
NCT00667394
Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumorstreatment2completed
NCT01095094
Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Gliomatreatment2terminated
NCT01331291
Bosutinib in Adult Patients With Recurrent Glioblastomatreatment2completed
NCT01445691
More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgerytreatment2withdrawn
NCT02644291
Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumorstreatment1completed
NCT05600491
A Phase III Study of Postoperative Early Temozolomide Treatment Plus STUPP Regimen for Newly Diagnosed GBM Multiformetreatment3recruiting
NCT06336291
A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrencetreatment2not_yet_recruiting
NCT02330991
A Trial of One-week on/One-week Off Temozolomide Versus Continuous Dose-Intense Temozolomide in Patients With Glioblastoma Multiforme at First Relapsetreatment2completed
NCT05502991
Sintilimab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for ctDNA-level-relapse and Clinical-relapse Glioblastomatreatment2not_yet_recruiting
NCT00939991
Suberoylanilide Hydroxamic Acid (SAHA), Bevacizumab, Daily Temozolomide for Recurrent Malignant Gliomastreatment1 / 2completed
NCT01752491
A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiformetreatment1active_not_recruiting
NCT03897491
PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastomatreatment2recruiting
NCT03743662
Nivolumab With Radiation Therapy and Bevacizumab for Recurrent MGMT Methylated Glioblastomatreatment2active_not_recruiting
NCT02717962
Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Settingtreatment2active_not_recruiting
NCT03434262
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumorstreatment1completed
NCT04391062
Dose Finding for Intraoperative Photodynamic Therapy of Glioblastomatreatment2recruiting
NCT04019262
Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastomatreatment1 / 2active_not_recruiting
NCT02754362
A Toll-like Receptor Agonist as an Adjuvant to Tumor Associated Antigens (TAA) Mixed With Montanide ISA-51 VG With Bevacizumab for Patients With Recurrent Glioblastomatreatment2withdrawn
NCT04752280
Glioblastoma Radiotherapy Using IMRT or Proton BeamsNo drug interventionstreatmentNot Availablerecruiting
NCT03107780
Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancertreatment1suspended
NCT01656980
Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Gliomatreatment3unknown_status
NCT02698280
Bevacizumab and Nimustine in Patients With Recurrent High Grade Gliomatreatment2completed
NCT00821080
Vandetanib and Sirolimus in Patients With Recurrent Glioblastomatreatment1completed
NCT00761280
Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastomatreatment3terminated
NCT02709889
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumorstreatment1 / 2terminated
NCT02768389
Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastomatreatment0completed
NCT06455189
Magnetic Resonance Fingerprinting Guided Extended Resection in GlioblastomasNo drug interventionstreatment1not_yet_recruiting
NCT05590689
Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumortreatment1 / 2recruiting
NCT05074992
A Trial of Neoadjuvant Therapy in Patients With Newly Diagnosed Glioblastomatreatment2terminated
NCT03581292
Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutationstreatment2active_not_recruiting
NCT01702792
Derivation of Tumor Specific Hybridomastreatment1terminated
NCT04900792
A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastomatreatment1recruiting
NCT03405792
Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP)treatment2active_not_recruiting
NCT05450744
131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2)treatment1recruiting
NCT04734444
SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain TissueNo drug interventionsotherNot Availablerecruiting
NCT02283944
TMS Electrochemotherapy for Glioblastoma MultiformeNo drug interventionstreatment2withdrawn
NCT02968940
Avelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant Glioblastomatreatment2completed
NCT03048240
INtraoperative photoDYnamic Therapy of GliOblastomatreatmentNot Availablecompleted
NCT04324840
A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastomatreatment1terminated
NCT03144167
Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of RadiochemotherapyNo drug interventionsotherNot Availableunknown_status
NCT00921167
A Study to Evaluate the Efficacy of Bevacizumab Plus Irinotecan in Recurrent Gliomastreatment2completed
NCT00684567
Temozolomide Phase II Clinical Study in Patients With Newly Diagnosed Glioblastoma Multiforme (Study P04661)(COMPLETED)treatment2completed
NCT01260467
Memantine for Recurrent Glioblastomatreatment2terminated
NCT01473901
A Phase I Dose Escalation Study of BKM120 With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastomatreatment1completed
NCT00944801
Pegylated Liposomal Doxorubicine and Prolonged Temozolomide in Addition to Radiotherapy in Newly Diagnosed Glioblastomatreatment1 / 2completed
NCT05410301
Golden Halo, Static Magnetic and Electric Field Device, in Recurrent GlioblastomatreatmentNot Availablewithdrawn
NCT06186401
Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cellstreatment1recruiting
NCT02833701
Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Gliomatreatment1terminated
NCT01514201
Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomastreatment1 / 2completed
NCT04002804
Immunotherapy With Autologous Tumor Lysate-Loaded Dendritic Cells In Patients With Recurrence Of Glioblastoma Multiformetreatment1terminated
NCT03224104
Study of TG02 in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastomatreatment1completed
NCT03615404
Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastomatreatment1completed
NCT02085304
Tumor Resection and Gliadel® Wafers, Followed by Temodar® With Standard Radiation or GammaKnife® for New GBMtreatment1 / 2terminated
NCT06038604
Glioblastoma Psychosocial Support ProgramNo drug interventionssupportive_careNot Availablecompleted
NCT03739372
Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade GliomaNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05062772
Brain Tumor Intraoperative Ultrasound DatabaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT05383872
Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain TumorsNo drug interventionsdiagnosticNot Availablerecruiting
NCT03770468
Molecular Genetic, Host-derived and Clinical Determinants of Long-term Survival in GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01310868
Gliadel Wafer and Fluorescence-Guided Surgery With 5-ALA Followed by Radiation Therapy And Temozolomide in Treating Patients With Primary Glioblastomatreatment2completed
NCT00045968
Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancertreatment3unknown_status
NCT01171469
Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumortreatment1completed
NCT04049669
Pediatric Trial of Indoximod with Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGtreatment2recruiting
NCT02903069
Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancertreatment1completed
NCT01259869
A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progressiontreatment2completed
NCT03390569
Exercise in Patients With GlioblastomaNo drug interventionssupportive_careNot Availablecompleted
NCT03514069
Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastomatreatment1active_not_recruiting
NCT01067469
Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM)treatment2completed
NCT00669669
O6-Benzylguanine-Mediated Tumor Sensitization With Chemoprotected Autologous Stem Cell in Treating Patients With Malignant Gliomastreatment1 / 2terminated
NCT04772846
Chloroquine for Glioblastoma.treatment1 / 2unknown_status
NCT02605746
Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasisother0completed
NCT05873946
Assessing the Effectiveness of 2D Non-Navigated Intraoperative Ultrasound in Glioma SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT00074646
Phase I Trial of CC-8490 for the Treatment of Subjects With Recurrent/Refractory High-Grade Gliomastreatment1completed
NCT04657146
Longitudinal Assessment of Marrow and Blood in Patients With GlioblastomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04608812
Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resectiontreatment1terminated
NCT02253212
Safety of BBB Opening With the SonoCloudtreatment1 / 2completed
NCT03477110
Temozolomide, Radiation Therapy, and Tumor Treating Fields Therapy in Treating Participants With Glioblastomatreatment0completed
NCT01967810
ANG1005 in Patients With Recurrent High-Grade Gliomatreatment2completed
NCT02207010
A Phase 0 Study of AZD1775 in Recurrent GBM Patientsother0completed
NCT04443010
Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed Glioblastomatreatment1 / 2recruiting
NCT05927610
Genetic Testing of Cerebrospinal Fluid to Diagnose and Monitor GlioblastomaNo drug interventionsdiagnosticNot Availablewithdrawn
NCT05974410
Expanded Access to Immunomodulatory AVM0703 for Solid Tumor and Blood Cancer PatientsNot AvailableNot Availableavailable
NCT00870181
ADV-TK Improves Outcome of Recurrent High-Grade Gliomatreatment2completed
NCT06001281
Predictive Value of Soluble CD146 in Glioblastoma PatientsNo drug interventionsbasic_scienceNot Availablerecruiting
NCT02329795
Image-derived Prediction of Response to Chemo-radiation in GlioblastomaNot AvailableNot Availableterminated
NCT05759195
Biomolecular Analysis for Predicting Response to RegorafenibNo drug interventionsotherNot Availablerecruiting
NCT03244995
Mind-Body Intervention in Glioma CouplesNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT03532295
Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomastreatment2active_not_recruiting
NCT03454295
Easing Psychosocial Burden for Informal CaregiversNo drug interventionssupportive_care0completed
NCT05753995
Immuno-Positron Emission Tomography (PET)-Glioma Study, a Proof-of-principle Imaging StudyNo drug interventionsdiagnosticNot Availablerecruiting
NCT01564914
A Phase 2 Evaluation of TRC105 In Combination With Bevacizumab in Patients With Glioblastomatreatment2completed
NCT03075514
Ketogenic Diets as an Adjuvant Therapy in GlioblastomaNo drug interventionstreatmentNot Availablecompleted
NCT02631655
POSitron Emission Imaging Using 18F-FDOPA in NeurooncologyNo drug interventionsdiagnosticNot Availablecompleted
NCT04547855
Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimentreatment2unknown_status
NCT05231655
Ex VIvo DEtermiNed Cancer TherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01310855
Cediranib Maleate With or Without Gefitinib in Treating Patients With Recurrent or Progressive Glioblastomatreatment2terminated
NCT02374255
Improving Goals of Care Discussion in Advanced Cancer PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT04863950
Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastomatreatment2recruiting
NCT03344250
Phase I EGFR BATs in Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT01149850
Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcomatreatment2completed
NCT03466450
Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastomatreatment1 / 2completed
NCT03535350
Ibrutinib With Radiation and Temozolomide in Patients With Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT04922723
Radiation/Temozolomide and Immunotherapy With Daratumumab to Improve Antitumor Efficacy in Glioblastomatreatment1 / 2recruiting
NCT02997423
Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)No drug interventionsNot AvailableNot Availablecompleted
NCT03661723
Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastomatreatment2active_not_recruiting
NCT00613223
Ph I Dose Escalation Trial of Vandetanib in Combo w Etoposide for Malignant Gliomastreatment1completed
NCT02458508
Retrospective Evaluation of Melanocortin Receptor 4 Polymorphisms in Patients With GBM Treated With RadiochemotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT00606008
A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastomatreatment2completed
NCT00704808
Post Marketing Surveillance: Newly Diagnosed Glioblastoma Multiforme Treated With Radiotherapy/Temozolomide and Adjuvant Temozolomide (Study P04739)Not AvailableNot Availablecompleted
NCT02799238
Autologuos Lymphoid Effector Cells Specific Against Tumour (ALECSAT) as Add on to Standard of Care in Patients With Glioblastomatreatment2completed
NCT02092038
Preoperative Chemoradiation for Glioblastomatreatment1completed
NCT06222138
Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed GlioblastomaNo drug interventionsotherNot Availablerecruiting
NCT04116138
Antisecretory Factor in Primary Glioblastoma 1No drug interventionstreatment1 / 2completed
NCT06132438
Immunotherapy Targeting of Cytomegalovirus Antigens in GlioblastomaNo drug interventionstreatment1not_yet_recruiting
NCT02974738
A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001)treatment1active_not_recruiting
NCT03868943
Solriamfetol in Improving Sleep in Patients With Grade II-IV Gliomasupportive_care2suspended
NCT05664243
A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed GlioblastomaNo drug interventionstreatment1 / 2recruiting
NCT02869243
A Dose Escalation Phase I Study Of Human- Recombinant Bone Morphogenetic Protein 4 Administrated Via CED In GBM Patientstreatment1completed
NCT05015543
Physical Training in Glioblastoma Patients During Cytotoxic TherapyNo drug interventionssupportive_careNot Availablerecruiting
NCT03403803
Prognosis and Therapeutic Biomarkers for Glioblastoma PatientsNo drug interventionsNot AvailableNot Availableterminated
NCT03149003
A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapytreatment3completed
NCT02157103
A Study of Subcutaneous Bevacizumab in Relapsed / Progressive Glioblastomatreatment2completed
NCT04047303
CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastomatreatment1terminated
NCT00179803
Stem Cell Transplant for High Risk Central Nervous System (CNS) TumorsNo drug interventionstreatment2completed
NCT02876003
Efficacy and Safety of G-202 in PSMA-Positive Glioblastomatreatment2withdrawn
NCT00961090
Safety Study of Aminolevulinic Acid (ALA) to Improve Visibility of Brain Tumors During Surgerytreatment2completed
NCT01861990
Valproic Acid in Childhood Progressive Brain Tumorstreatment1withdrawn
NCT01604590
Imaging Biomarkers of Tissue Microstructure and Vasculature as Predictors of Glioblastoma MultiformeNo drug interventionsNot AvailableNot Availablecompleted
NCT01622764
89Zr-RO5323441 PET Imaging in GlioblastomaNo drug interventionsother2withdrawn
NCT03119064
BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent Glioblastomatreatment1 / 2terminated
NCT00864864
Sunitinib Tumor Levels in Patients Not on Enzyme-Inducing Anti-Epileptic Drugs Undergoing Debulking Surgery for Recurrent Glioblastomatreatment0completed
NCT01364064
Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastomatreatment3completed
NCT04590664
Verteporfin for the Treatment of Recurrent High Grade EGFR-Mutated Glioblastomatreatment1 / 2recruiting
NCT03649464
Investigation of Oral OKN-007 in Recurrent High-grade Glioma Participantstreatment1 / 2withdrawn
NCT05186064
Glioblastoma Targeted Treatment Option Maximization by WGSNo drug interventionsdiagnosticNot Availablerecruiting
NCT02808364
Personalized Cellular Vaccine for Recurrent Glioblastoma (PERCELLVAC2)No drug interventionstreatment1completed
NCT05781321
Short Course Radiotherapy for the Treatment of Patients With Glioblastoma, SAGA Studytreatment2recruiting
NCT01872221
Study of the Capacity of the MRI Spectroscopy to Define the Tumor Area Enriched in Glioblastoma Stem Cells. Proof of Concept StudyNo drug interventionsotherNot Availablecompleted
NCT05793021
FKBP51s: a New Molecular Biomarker for Glioblastoma? Pre- and Post-operative Blood Levels Evaluation of FKBP51s Protein and Correlation With MRI PhenotypeNo drug interventionsdiagnosticNot Availablerecruiting
NCT03258021
TTFields In GErmany in Routine Clinical CareNo drug interventionsNot AvailableNot Availableunknown_status
NCT01811121
MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMASNo drug interventionstreatment3unknown_status
NCT03020602
BPM31510 in Treating Patients With Recurrent High-Grade Glioma Previously Treated With Bevacizumabtreatment1completed
NCT00597402
Avastin in Combination With Radiation (XRT) & Temozolomide, Followed by Avastin, Temozolomide and Irinotecan for Glioblastoma (GBM) and Gliosarcomastreatment2completed
NCT04181684
LITT Followed by Hypofractionated RT for Recurrent GliomasNo drug interventionstreatmentNot Availablerecruiting
NCT04661384
Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or MedulloblastomaNo drug interventionstreatment1recruiting
NCT03922984
Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in GlioblastomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT04315584
FDG and FDOPA PET Demonstration of Functional Brain AbnormalitiesNo drug interventionsdiagnostic0unknown_status
NCT01989884
An Efficacy Study Of Ortataxel In Recurrent Glioblastomatreatment2completed
NCT01204684
Dendritic Cell Vaccine for Patients With Brain Tumorstreatment2completed
NCT01480479
Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastomatreatment3completed
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT04630379
Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their CaregiversNo drug interventionssupportive_careNot Availablecompleted
NCT03395587
Efficiency of Vaccination With Lysate-loaded Dendritic Cells in Patients With Newly Diagnosed Glioblastomatreatment2recruiting
NCT03749187
BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomastreatment1recruiting
NCT05938387
Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or AstrocytomaNo drug interventionstreatment1recruiting
NCT05835687
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS TumorsNo drug interventionstreatment1recruiting
NCT01985087
A Study Using Radiation Therapy and Temozolomide to Treat Glioblastoma in Patients Over 70treatment1 / 2recruiting
NCT05515133
Correlation Between Psychological Stress and Disease Progression in Newly Diagnosed Glioblastoma PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03739333
Early Diagnosis of Pseudoprogression Using 11C-Methionine PET-MRI After Concomitant Radiochemotherapy Treatment for Glioblastoma.No drug interventionsdiagnosticNot Availablerecruiting
NCT04516733
Precoce Medical Care by the Mobil Support for Patients With GlioblastomaNo drug interventionssupportive_careNot Availablecompleted
NCT06388733
A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastomatreatment3recruiting
NCT04388033
Clinical Study of an Dendritic and Glioma Cells Fusion Vaccine With IL-12 for Treatment-naïve GBM Patients.treatment1 / 2unknown_status
NCT03679754
Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102treatment1completed
NCT05986851
Azeliragon in MGMT Unmethylated Glioblastomatreatment2active_not_recruiting
NCT03243851
Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastomatreatment2completed
NCT01430351
Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapytreatment1active_not_recruiting
NCT01499251
Clinical Study on the Safety and Tolerability of Macitentan in Combination With Dose-dense Temozolomide in Patients With Recurrent Glioblastomatreatment1terminated
NCT01637753
Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Recurrent Malignant GliomatreatmentNot Availableunknown_status
NCT00385853
PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugstreatment1completed
NCT01579253
Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04266977
Restrictive Use of Dexamethasone in GlioblastomatreatmentNot Availablerecruiting
NCT04681677
Recurrent GBM Treated With Neurosurgical Resection and IORT Using the Xoft Axxent eBx System and Bevacizumabtreatment2terminated
NCT05139277
Evaluation of the CONVIVO SystemNo drug interventionsdiagnosticNot Availablerecruiting
NCT03970447
A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastomatreatment2 / 3recruiting
NCT04802447
SurVaxM Expanded Access ProtocolNot AvailableNot Availableno_longer_available
NCT02617745
Impact of the Platelet Level in Patients Treated for Glioblastoma With TemozolomidNo drug interventionsother2active_not_recruiting
NCT01086345
Radiosurgery Plus Bevacizumab in Glioblastomatreatment0terminated
NCT04747145
Analyzing Pulsed Reduced Dose Radiotherapy in Upfront Glioblastomatreatment2recruiting
NCT05686798
Adenovirus Mediated Suicide Gene Therapy With Radiotherapy in Progressive Astrocytoma.No drug interventionstreatment1recruiting
NCT03861598
Carvedilol With Chemotherapy in Second Line Glioblastoma and Response of Circulating Tumor Cellstreatment0terminated
NCT02861898
Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastomatreatment1 / 2recruiting
NCT02511405
A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)treatment3completed
NCT06147505
Natural Killer (NK) Cells (XS005) Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM)treatment1 / 2recruiting
NCT02685605
Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiformetreatment3active_not_recruiting
NCT05182905
AZD1390 in Recurrent and Newly Diagnosed WHO Grade 4 Glioma PatientsNo drug interventionstreatment0recruiting
NCT03603405
HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBMtreatment1 / 2recruiting
NCT03174197
Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastomatreatment1 / 2active_not_recruiting
NCT06490497
Expectations and Needs of a Glioblastoma CaregiverNo drug interventionsNot AvailableNot Availablecompleted
NCT00029783
Efficacy of Distant Healing in Glioblastoma TreatmentNo drug interventionstreatment2completed
NCT06183983
Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of GlioblastomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00337883
A Study of the Safety and Efficacy of Tarceva in Patients With First Relapse of Grade IV Glioma (Glioblastoma Multiforme)treatment2completed
NCT02133183
Sapanisertib Before and After Surgery in Treating Patients With Recurrent Glioblastomatreatment1terminated
NCT04974983
Impact of Bevacizumab on Symptom Burden and Neurological Deficits in Patients With Recurrent GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04270461
NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumorstreatment1withdrawn
NCT04221061
18F-FluorThanatrace (PET/CT) in GlioblastomaNo drug interventionsdiagnostic0terminated
NCT02465528
Ceritinib Rare Indications Study in ALK+ Tumorstreatment2terminated
NCT00613028
Ph II Bev + Either Temozolomide/Etoposide for GBM Pts Who Have Failed Bev + Irinotecantreatment2completed
NCT01498328
A Study of Rindopepimut/GM-CSF in Patients With Relapsed EGFRvIII-Positive Glioblastomatreatment2completed
NCT05109728
A Dose Finding Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Standard of Care and in Recurrent Glioblastoma as a Single Agent.treatment1recruiting
NCT00611728
Ph I SU011248 + Irinotecan in Treatment of Pts w MGtreatment1completed
NCT02366728
DC Migration Study for Newly-Diagnosed GBMtreatment2completed
NCT06136611
Preoperative Preradiotherapy TTFieldsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06348693
Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related AggressivenessNo drug interventionsNot AvailableNot Availablerecruiting
NCT05811793
Efficacy and Safety of SCAI of Bevacizumab Combined With IC of Tislelizumab in the Treatment of Recurrent Glioblastoma.treatmentNot Availablenot_yet_recruiting
NCT04826393
ASP8374 + Cemiplimab in Recurrent Gliomatreatment1active_not_recruiting
NCT03025893
A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiformetreatment2 / 3unknown_status
NCT01867593
MET-PET for Newly Diagnosed GlioblastomaNo drug interventionsdiagnostic0completed
NCT00392171
The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601)treatment2completed
NCT04708171
The PROGRAM-study: Awake Mapping Versus Asleep Mapping Versus No Mapping for Glioblastoma ResectionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00001171
Evaluation of Factors in Human Brain TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT03919071
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Gliomatreatment2recruiting
NCT00610571
Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomastreatment1completed
NCT03776071
A Trial of Enzastaurin Plus Temozolomide During and Following Radiation Therapy in Patients With Newly Diagnosed Glioblastoma With or Without the Novel Genomic Biomarker, DGM1treatment3completed
NCT03194971
NovoTTF Treatment Signatures in Glioblastoma Patients at AutopsyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01798771
Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor SurgeryNo drug interventionstreatmentNot Availableunknown_status
NCT02663271
TTFields and Pulsed Bevacizumab for Recurrent Glioblastomatreatment2terminated
NCT02039778
Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade GliomaNo drug interventionstreatmentNot Availableterminated
NCT03383978
Intracranial Injection of NK-92/5.28.z Cells in Combination With Intravenous Ezabenlimab in Patients With Recurrent HER2-positive Glioblastomatreatment1active_not_recruiting
NCT02327078
A Study of the Safety, Tolerability, and Efficacy of Epacadostat Administered in Combination With Nivolumab in Select Advanced Cancers (ECHO-204)treatment1 / 2completed
NCT04157478
Addition of Anlotinib Hydrochloride to the Stupp Regimen Versus the Stupp Regimen Alone for Newly Diagnosed Glioblastomatreatment2not_yet_recruiting
NCT01441388
A Study Of Crizotinib Plus VEGF Inhibitor Combinations In Patients With Advanced Solid Tumors.treatment1withdrawn
NCT04822688
Analysis of Cell Count, Viability, and Immunogenicity of Discarded Newly Diagnosed Glioblastoma Tissue or Solid Tumor TissuesNo drug interventionsNot AvailableNot Availablerecruiting
NCT01765088
A Phase III Trial on Adjuvant Temozolomide With or Without Interferon-alpha in Newly Diagnosed High-grade Gliomastreatment3unknown_status
NCT03018288
Radiation Therapy Plus Temozolomide and Pembrolizumab With and Without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)treatment2terminated
NCT01602588
A Randomised Trial Investigating the Additional Benefit of Hydroxychloroquine(HCQ)to Short Course Radiotherapy (SCRT) in Patients Aged 70 Years and Older With High Grade Gliomas (HGG)treatment2completed
NCT05753007
A Clinical Trial of a Hemp-Derived, High Cannabidiol Product for Anxiety in Glioblastoma Patientstreatment2recruiting
NCT05798507
Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastomatreatment0recruiting
NCT01392209
Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant GliomaNo drug interventionstreatment1completed
NCT04629209
A Phase II, Open Label Study of ONC201 in Adults With EGFR-low Glioblastomatreatment2withdrawn
NCT01149109
Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patientstreatment3completed
NCT04222309
Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM)No drug interventionstreatment1suspended
NCT02372409
Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumorstreatment2terminated
NCT01208909
Combined Approach to Resection of Glioblastoma (GBM) by 5-Aminolevulinic Acid (5-ALA) and Intraoperative Magnetic Resonance Imaging (MRI)No drug interventionsNot AvailableNot Availableunknown_status
NCT05990556
Research on the Safety and Efficacy of Blocking Dural Blood Supply in Glioblastoma PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT00846456
Safe Study of Dendritic Cell (DC) Based Therapy Targeting Tumor Stem Cells in GlioblastomaNo drug interventionstreatment1 / 2completed
NCT05929456
Multispectral Bimodal Fluorescence Guided Surgery of High-grade Glioma With Cetuximab-800CW and 5-ALA (5-aminolevulinic Acid)diagnostic1recruiting
NCT04074785
Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6treatment0active_not_recruiting
NCT04007185
Surgically Induced Neurological Deficits in Glioblastomas (SIND Study)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04566185
Evaluation of the Predictive Value of 18F-fluorodeoxyglucose Positron Emission Tomography and Brain Perfusion Computed Tomography for the Efficacy of Anti-angiogenic Therapy (Bevacizumab) in Recurrent GlioblastomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03782415
Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastomatreatment1 / 2active_not_recruiting
NCT03726515
CART-EGFRvIII + Pembrolizumab in GBMtreatment1completed
NCT04970615
Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed ModelsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00576537
Tumor Lysate Pulsed Dendritic Cell Immunotherapy for Patients With Brain Tumorstreatment2completed
NCT01174537
New Castle Disease Virus (NDV) in Glioblastoma Multiforme (GBM), Sarcoma and NeuroblastomaNo drug interventionstreatment1 / 2withdrawn
NCT00694837
Study With Nelfinavir and Combined Radiochemotherapy for Glioblastomatreatment1completed
NCT04913337
Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignanciestreatment1 / 2active_not_recruiting
NCT04642937
Study of CD200 Activation Receptor Ligand (CD200AR-L) and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent GlioblastomaNo drug interventionstreatment1active_not_recruiting
NCT03493932
Cytokine Microdialysis for Real-Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockadetreatment1completed
NCT03439332
Multicentre Validation of How Vascular Biomarkers From Tumor Can Predict the Survival of the Patient With GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00613132
Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MGtreatment1completed
NCT04881032
AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastomatreatment1 / 2recruiting
NCT01308632
Metronomic Temozolamide in Patients With Recurrent Glioblastomatreatment2 / 3unknown_status
NCT00790452
Aspirin Prophylaxis for Venous Thromboembolism in Glioblastomatreatment2terminated
NCT01849952
Evaluating the Expression Levels of MicroRNA-10b in Patients With GliomasNo drug interventionsNot AvailableNot Availablerecruiting
NCT01339052
Phase II Study of BKM120 for Subjects With Recurrent Glioblastomatreatment2completed
NCT04856852
Iodine-125 Brachytherapy Together With Chemotherapy in Patients With Newly Diagnosed GlioblastomaNo drug interventionstreatmentNot Availableunknown_status
NCT01392352
HYPAZ: Hypertension Induced by Pazopanibbasic_science2terminated
NCT03393000
Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjectstreatment3terminated
NCT05376800
A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastomatreatment1recruiting
NCT05656300
Glioblastoma Imaging Using a Strong Iron-like Bloodpool Contrast Medium?No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04015700
Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastomatreatment1active_not_recruiting
NCT05513859
Investigational Imaging Technique During Brain SurgeryNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT03363659
Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma Multiformetreatment2terminated
NCT03975959
Memory Perception Assessment in Central/Non-central Nervous System CancersNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT00703859
Combining Radiotherapy and Temozolomide With Dichloroacetate in Patients With Newly Diagnosed Glioblastomatreatment1withdrawn
NCT04825275
Neuro-pharmacological Properties of Repurposed Posaconazole in Glioblastoma: A Phase 0 Clinical Trialtreatment0recruiting
NCT06140875
Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With Radiochemotherapy and Maintenance Chemotherapy in Patients With Glioblastoma (Brain-RF)No drug interventionstreatmentNot Availablerecruiting
NCT03149575
VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBMtreatment3terminated
NCT01345370
Comparison of Different Methods to Test MGMT Status in Glioblastoma PatientsNot AvailableNot Availablecompleted
NCT02761070
Bevacizumab Alone Versus Dose-dense Temozolomide Followed by Bevacizumab for Recurrent Glioblastoma, Phase IIItreatment3active_not_recruiting
NCT01250470
Vaccine Therapy and Sargramostim in Treating Patients With Malignant Gliomatreatment1completed
NCT02168270
Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Gliomatreatment1terminated
NCT03717142
Feasibility of the LUM Imaging System for Detection of Cancer to the BrainNo drug interventionsotherNot Availablesuspended
NCT05541042
Radiogenomics in Glioblastoma: Correlation Between Multiparametric Imaging Biomarkers and Genetic BiomarkersNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03451799
Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastomatreatment1active_not_recruiting
NCT02766699
A Study to Evaluate the Safety, Tolerability and Immunogenicity of EGFR(V)-EDV-Dox in Subjects With Recurrent Glioblastoma Multiforme (GBM)No drug interventionstreatment1unknown_status
NCT03687099
Immunological and Functional Characterization of Cellular Population CD45+ Infiltrating Human GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00609999
Ph I Dasatinib + Erlotinib in Recurrent MGtreatment1completed
NCT06333899
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusiontreatment0not_yet_recruiting
NCT05698199
Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM)No drug interventionstreatment1active_not_recruiting
NCT06108206
Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade GliomaNo drug interventionstreatmentNot Availablerecruiting
NCT03995706
Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0treatment0completed
NCT03956706
Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant GliomasNo drug interventionstreatmentNot Availablewithdrawn
NCT02769806
Advanced Perfusion MRI of Treatment Response and Progression in GlioblastomaNo drug interventionsNot AvailableNot Availableterminated
NCT02798406
Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effectstreatment2completed
NCT05267106
Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterationstreatment2active_not_recruiting
NCT04869449
Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomastreatment0recruiting
NCT03551249
Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) DisruptionNo drug interventionstreatmentNot Availablecompleted
NCT01836549
Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumorstreatment2terminated
NCT02728349
Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastomatreatment1completed
NCT03643549
Bortezomib and Temozolomide in Recurrent Grade-4 Glioma Unmethylated MGMT Promoter (BORTEM-17)treatment1 / 2recruiting
NCT04536649
Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma.No drug interventionstreatment3not_yet_recruiting
NCT03631836
Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastomatreatment1unknown_status
NCT01043536
Dose Escalation Radiotherapy With Modulation of Intensity and Integrated Boost (SIB-IMRT) in the Treatment of Glioblastomas in Adultstreatment1completed
NCT01836536
Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patientsbasic_scienceNot Availablecompleted
NCT04118036
Abemaciclib + Pembrolizumab In Glioblastomatreatment2withdrawn
NCT04752813
A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)treatment2recruiting
NCT04963413
RENEW: Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.No drug interventionstreatment1terminated
NCT05076513
Trial of Niraparib in Participants With Newly-diagnosed Glioblastoma and Recurrent Gliomatreatment0recruiting
NCT03152318
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2treatment1recruiting
NCT05432518
Pilot Trial for Treatment of Recurrent Glioblastomatreatment0recruiting
NCT03973918
Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGGtreatment2terminated
NCT05768919
Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade GliomasNo drug interventionstreatment1 / 2recruiting
NCT04006119
Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastomatreatment2completed
NCT05476341
A Phase I Clinical Trial of Bevacizumab Injectiontreatment1completed
NCT00884741
Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastomatreatment3completed
NCT02375841
Coping With Glioblastoma: A Study of Communication Between Physicians, Patients, and CaregiversNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04479241
LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastomatreatment2active_not_recruiting
NCT00576641
Immunotherapy for Patients With Brain Stem Glioma and GlioblastomaNo drug interventionstreatment1completed
NCT02887417
Glioblastoma Platelet Activation StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03347617
Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastomatreatment2active_not_recruiting
NCT03687034
A Study of the Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastomatreatment1unknown_status
NCT01227434
A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastomatreatment2terminated
NCT02315534
A Study of BBI608 in Combination With Temozolomide in Adult Patients With Recurrent or Progressed Glioblastomatreatment1 / 2completed
NCT03714334
DNX-2440 Oncolytic Adenovirus for Recurrent GlioblastomaNo drug interventionstreatment1terminated
NCT03971734
Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomastreatment1terminated
NCT06368934
Sub-lobectomy for IDH Wild-type and TERT Promoter Mutant GlioblastomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00190424
Randomized Phase 2 With CpG-ODN in Malignant GlioblastomaNo drug interventionstreatment2completed
NCT05698524
A Study of Temodar With Abexinostat (PCI-24781) for Patients With Recurrent Gliomatreatment1recruiting
NCT02573324
A Study of ABT-414 in Participants With Newly Diagnosed Glioblastoma (GBM) With Epidermal Growth Factor Receptor (EGFR) Amplificationtreatment3completed
NCT04606316
Surgical Nivolumab And Ipilimumab For Recurrent GBMtreatment1active_not_recruiting
NCT01331616
Optic Neuropathy in 10 Patients With Glioblastoma Receiving Bevacizumabtreatment0withdrawn
NCT03139916
Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastomatreatment2completed
NCT02709616
Personalized Cellular Vaccine for Glioblastoma (PERCELLVAC)No drug interventionstreatment1completed
NCT03626896
Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) PatientsNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT00028158
Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain CancerNo drug interventionstreatment1 / 2completed
NCT01740258
Bevacizumab Beyond Progression (BBP)treatment2completed
NCT05653635
Contribution From PET-DOPA in Glioblastoma Re-irradiation - A Randomized Phase II StudyNo drug interventionstreatment2not_yet_recruiting
NCT04188535
Serial MRI Scans During Radiation TherapyNo drug interventionsotherNot Availablerecruiting
NCT04656535
AB154 Combined With AB122 for Recurrent Glioblastomatreatment0recruiting
NCT03567135
Temozolomide Plus Anti-angiogenesis Drugs and Radiotherapy as a Treatment for GlioblastomaNot AvailableNot Availableunknown_status
NCT00009035
Natural History of Patients With Brain and Spinal Cord TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT05131763
NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumorstreatment1unknown_status
NCT06017063
Coaching for Coping in Glioblastoma Patients and Caregivers and Its Association With Compliance to TTFieldsNo drug interventionsotherNot Availablenot_yet_recruiting
NCT02430363
Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of The PI3K/Akt Pathway In Compared With MK-3475treatment1 / 2unknown_status
NCT00777686
Measuring Non-Enhancing Glioblastoma ProgressionNo drug interventionsNot AvailableNot Availablecompleted
NCT06492486
Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence WorkflowNo drug interventionstreatment2not_yet_recruiting
NCT04552886
Dendritic Cell Vaccination With Standard Postoperative Chemoradiation for the Treatment of Adult Glioblastomatreatment1completed
NCT03294486
Safety and Efficacy of the ONCOlytic VIRus Armed for Local Chemotherapy, TG6002/5-FC, in Recurrent Glioblastoma Patientstreatment1 / 2unknown_status
NCT03475186
Testing Ramipril to Prevent Memory Loss in People With Glioblastomasupportive_care2active_not_recruiting
NCT04902586
Effect of Radiotherapy Concurrent of TTFields in Patients With GlioblastomaNo drug interventionstreatmentNot Availableunknown_status
NCT06448286
PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glioblastomatreatment3not_yet_recruiting
NCT04717739
TIGER PRO-Active - Daily Activity, Sleep and Neurocognitive Functioning StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01120639
Phase 1-2 of Temozolomide and Hypofractionated Radiotherapy in Tx of Supratentorial Glioblastoma Multiformtreatment1 / 2completed
NCT05539339
Personalized Trial in ctDNA-level-relapse GlioblastomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02844439
Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastomatreatment2completed
NCT04910022
Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent Glioblastomatreatment1 / 2recruiting
NCT04933422
CM93 Treatment in Subjects With Epidermal Growth Factor Receptor (EGFR)-Modified Recurrent Glioblastoma (rGBM)No drug interventionstreatment1not_yet_recruiting
NCT06146725
The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)No drug interventionsNot AvailableNot Availablerecruiting
NCT05728125
Pinpointing the Factors Affecting Clinical Trial Experiences of Glioblastoma PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03663725
Treatment Intensification With Temozolomide in Adults With a GlioblastomaNo drug interventionstreatment3recruiting
NCT00686725
Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)treatment4completed
NCT04596930
MR-guided LITT Therapy in Patients With Primary Irresectable GlioblastomaNo drug interventionstreatmentNot Availablecompleted
NCT02843230
Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRINo drug interventionsNot AvailableNot Availablecompleted
NCT00612430
Ph II Bevacizumab + Etoposide for Pts w Recurrent MGtreatment2completed
NCT02630030
Phase 0 Analysis of Ixazomib (MLN9708) in Patients With Glioblastomabasic_science0completed
NCT03529448
TN-TC11G (THC+CBD) Combination With Temozolomide and Radiotherapy in Patients With Newly-diagnosed Glioblastomatreatment1 / 2recruiting
NCT02209948
Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.treatment2completed
NCT04678648
A Trial of RSC-1255 for Treatment of Patients With Advanced MalignanciesNo drug interventionstreatment1recruiting
NCT01986348
Study Evaluating the Efficacy and Safety of Selinexor (KPT-330) in Participants With Recurrent Gliomastreatment2terminated
NCT00001148
Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the TumorNo drug interventionsNot AvailableNot Availablecompleted
NCT03008148
Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBMtreatment2 / 3recruiting
NCT02455557
SurVaxM Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastomatreatment2active_not_recruiting
NCT04205357
Sulfasalazine and Stereotactic Radiosurgery for Recurrent Glioblastomatreatment1completed
NCT03707457
Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastomatreatment1terminated
NCT04846257
Specific Preoperative Dynamic Contrast-enhanced MRI Semi-quantitative Markers Can Correlate With Vascularity in Specific Areas of the Glioblastoma Tissue and Predict RecurrenceNo drug interventionsNot AvailableNot Availablecompleted
NCT05970757
Physiological MRI for Precision Radiotherapy IDH-wildtype GlioblastomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00943826
A Study of Bevacizumab (Avastin®) in Combination With Temozolomide and Radiotherapy in Participants With Newly Diagnosed Glioblastomatreatment3completed
NCT04982926
A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor CancerNo drug interventionstreatment1active_not_recruiting
NCT05773326
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGGtreatment0recruiting
NCT00734526
Phase I Portion of Phase I/II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcomatreatment1terminated
NCT01082926
Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2treatment1completed
NCT04200066
A Study of Maprotiline in Combination With Tamoxifen and Temozolomide for Recurrent Glioblastomatreatment1withdrawn
NCT06176066
PH Sensitive MRI Based Resections of GlioblastomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01242566
Temozolomide in Elderly Patients With KPS < 70treatment2completed
NCT04424966
Infigratinib in Recurrent High-Grade Glioma Patientstreatment0terminated
NCT00687765
Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Gliomatreatment1 / 2completed
NCT02336165
Phase 2 Study of Durvalumab (MEDI4736) in Patients With Glioblastomatreatment2completed
NCT01907165
Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomidetreatment0completed
NCT01939574
A Explore Study of Bevacizumab Combined With Conventional Therapy in GlioblastomaNo drug interventionstreatmentNot Availableunknown_status
NCT03212274
Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutationstreatment2active_not_recruiting
NCT01004874
Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastomatreatment2completed
NCT01723020
A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myelomatreatment1completed
NCT05641220
Biopsy Versus Resection in Elderly Glioblastoma Patients. A Prospective Cohort Study.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05669820
Antisecretory Factor Glioblastoma Phase 2No drug interventionstreatment2 / 3recruiting
NCT04541082
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsNo drug interventionstreatment1recruiting
NCT02661282
Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastomatreatment1 / 2completed
NCT05556382
Glioblastoma Evaluation for Heterogeneity In RadioseNsitivityNo drug interventionsNot AvailableNot Availablerecruiting
NCT00521482
Temozolomide vs. Temozolomide and Thalidomide Treatment in Recurrent Glioblastomatreatment2unknown_status
NCT02367482
Tryptophan Metabolism in Human Brain TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00734682
A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomastreatment1completed
NCT03460782
An Expanded Access Program of Ipilimumab for Patients With Glioblastomas and GliomasNot AvailableNot Availableno_longer_available
NCT05281731
Sonobiopsy for Noninvasive and Sensitive Detection of GlioblastomaNo drug interventionsdiagnosticNot Availablerecruiting
NCT00977431
Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma Multiformtreatment1completed
NCT04763031
Recurrent GBM With Maximal Neurosurgical Removal and Treatment With IORTNo drug interventionstreatmentNot Availableterminated
NCT02669173
Capecitabine + Bevacizumab in Patients With Recurrent Glioblastomatreatment1active_not_recruiting
NCT02575027
Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma MultiformeNo drug interventionstreatmentNot Availablecompleted
NCT05171127
Differentiation Between Healthy Cerebral Tissue and Tumor Tissue Using a Tissue Sensing InstrumentNo drug interventionsNot AvailableNot Availablecompleted
NCT00615927
Phase II Imatinib + Hydroxyurea in Treatment of Patients With Recurrent/Progressive Grade II Low-Grade Glioma (LGG)treatment2completed
NCT01922076
Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomastreatment1completed
NCT02227576
Prevention of Thrombocytopenia in Glioblastoma Patientstreatment2terminated
NCT06273176
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent GlioblastomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04691960
A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imagingtreatment2recruiting
NCT06552260
A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastomatreatment0not_yet_recruiting
NCT06038760
Prospective Evaluation of AI R&D Tool in Adult Glioma and Other Primary Brain Tumours (PEAR-GLIO)No drug interventionsNot AvailableNot Availablerecruiting
NCT00941460
Comparison of Two Dosing Regimens of Temozolomide in Patients With Progressive or Recurrent Glioblastomatreatment2completed
NCT03355794
A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)treatment1completed
NCT02772094
Dendritic Cell-Based Tumor Vaccine Adjuvant Immunotherapy of Human Glioblastoma Multiforme (WHO Grade IV Gliomas)No drug interventionstreatment2unknown_status
NCT05820191
B-amyloid as a Marker for GBM Bioimagingdiagnostic2not_yet_recruiting
NCT03043391
Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Childrentreatment1completed
NCT02750891
A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade GliomasNo drug interventionstreatment1 / 2completed
NCT02337491
Pembrolizumab +/- Bevacizumab for Recurrent GBMtreatment2completed
NCT03426891
Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastomatreatment1completed
NCT02330562
Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumabtreatment1 / 2completed
NCT02977780
INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)treatment2recruiting
NCT03746080
Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastomatreatment2active_not_recruiting
NCT04528680
Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastomatreatment1 / 2recruiting
NCT04216329
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT03975829
Pediatric Long-Term Follow-up and Rollover Studytreatment4recruiting
NCT04610229
Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas.No drug interventionstreatmentNot Availablecompleted
NCT04814329
Glioblastoma Response Prediction to ApatinibNo drug interventionsNot AvailableNot Availablecompleted
NCT03630289
Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBMNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT00948389
Study of CCNU (Lomustine) Plus Dasatinib in Recurrent Glioblastoma (GBM)treatment1 / 2terminated
NCT00612989
Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBMtreatment1completed
NCT05241392
Safety and Efficacy Study of Anti-B7-H3 CAR-T Cell Therapy for Recurrent GlioblastomaNo drug interventionstreatment1recruiting
NCT00960492
Safety Study of XL184 (Cabozantinib) in Combination With Temozolomide and Radiation Therapy in the Initial Treatment of Adults With Glioblastomatreatment1completed
NCT04573192
A Study to Evaluate Safety and Efficacy of L19TNF Plus Lomustine in Patients With Glioblastoma at First Progressiontreatment1 / 2recruiting
NCT02525692
Oral ONC201 in Recurrent GBM, H3 K27M Glioma, and Midline Gliomatreatment2active_not_recruiting
NCT05557292
RMC-5552 Monotherapy in Adult Subjects With Recurrent GlioblastomaNo drug interventionstreatment1recruiting
NCT01810744
Study of Microcirculatory Effects of Bevacizumab in Patients Treated for Metastatic Colon Cancer or GlioblastomaNo drug interventionsdiagnosticNot Availablecompleted
NCT02014844
Phase 2 Study to Investigate the Efficacy and Safety of Aldoxorubicin in Subjects With Glioblastomatreatment2completed
NCT00115440
BNCT to Treat Glioma That Has Progressed Following RadiotherapyNo drug interventionstreatment1 / 2completed
NCT02981940
A Study of Abemaciclib in Recurrent Glioblastomatreatment2active_not_recruiting
NCT05772767
Modulation of Ciliogenesis in Glioma Stem CellsNo drug interventionsbasic_scienceNot Availablerecruiting
NCT03718767
Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotypetreatment2recruiting
NCT05879367
Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastomatreatment1recruiting
NCT06279767
Efficacy and Safety of TMZ Plus 6-MP in the Patients With Recurrent Glioblastomatreatment1 / 2recruiting
NCT00657267
Dose-Intense Temozolomide in Recurrent Glioblastomatreatment2completed
NCT02655601
Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001treatment2active_not_recruiting
NCT03231501
HMPL-813 in Treating Patients With GlioblastomaNo drug interventionstreatment1unknown_status
NCT02910804
IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With GlioblastomaNo drug interventionsdiagnostic0unknown_status
NCT05183204
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastomatreatment2recruiting
NCT03151772
Bioavailability of Disulfiram and Metformin in Glioblastomasother0terminated
NCT02431572
A Pilot Study to Evaluate PBR PET in Brain Tumor Patients Treated With Chemoradiation or ImmunotherapyNo drug interventionsdiagnosticNot Availablecompleted
NCT02529072
Nivolumab With DC Vaccines for Recurrent Brain Tumorstreatment1completed
NCT02062372
Spatial Analysis and Validation of Glioblastoma on 7 T MRINo drug interventionsdiagnosticNot Availableterminated
NCT04406272
VB-111 in Surgically Accessible Recurrent/Progressive GBMtreatment2terminated
NCT00397072
Epothilone in Recurrent Glioblastoma Patientstreatment2completed
NCT03388372
Nimotuzumab Plus Radiotherapy With Concomitant and Adjuvant Temozolomide for Cerebral Glioblastomatreatment2completed
NCT05538572
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid TumorsNo drug interventionstreatment1completed
NCT02379572
Impact of iMRI on the Extent of Resection in Patients With Newly Diagnosed GlioblastomasNo drug interventionstreatmentNot Availablecompleted
NCT02465268
Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiformetreatment2completed
NCT02864368
Peptide Targets for Glioblastoma Against Novel Cytomegalovirus Antigenstreatment1terminated
NCT05099068
Profiling Program of Cancer Patients With Sequential Tumor and Liquid Biopsies (PLANET)No drug interventionsdiagnosticNot Availablerecruiting
NCT01582269
A Study in Recurrent Glioblastoma (GB)treatment2active_not_recruiting
NCT05660369
CARv3-TEAM-E T Cells in GlioblastomaNo drug interventionstreatment1recruiting
NCT01700569
Phase-1 Study of Folinic Acid to Modulate MGMT Gene in Glioblastomatreatment1terminated
NCT05039346
Quality of Life and Patient Needs in Advanced High Grade GliomasNo drug interventionsNot AvailableNot Availablecompleted
NCT04323046
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adultstreatment1recruiting
NCT01849146
Adavosertib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastomatreatment1active_not_recruiting
NCT06297512
Evaluate the Role of Anthracycline After Radio Therapy in Patients With Glioblastoma (pGBM).treatment2recruiting
NCT00725010
Temozolomide in Concomitant Radiochemotherapy Followed by Sequential Temozolomide Chemotherapy - Observational Program (Study P04816)Not AvailableNot Availablecompleted
NCT01225510
A Trial Of PF-04856884 In Patients With Recurrent Glioblastomatreatment2withdrawn
NCT02880410
Feasibility Study on LITT for Newly Diagnosed Glioblastomatreatment1terminated
NCT01759810
Proteome-based Personalized Immunotherapy of GlioblastomaNo drug interventionstreatment2 / 3unknown_status
NCT02658981
Anti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)treatment1completed
NCT04391595
LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patientstreatment0recruiting
NCT05512195
Safety and Efficacy of a New Approach to Delineating Clinical Target Volume of GlioblastomaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00693095
Evaluation of Recovery From Drug-Induced Lymphopenia Using Cytomegalovirus-specific T-cell Adoptive TransferNo drug interventionstreatment1completed
NCT02858895
Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastomatreatment2completed
NCT04903795
Bispecific T Cell Engager BRiTE for Patients With Grade IV Malignant GliomaNo drug interventionstreatment1not_yet_recruiting
NCT06041555
MRI Guided Radiotherapy and Radiobiological Data: the ISRAR Database (Irm Sequences for Radiobiological Adaptative Radiotherapy)No drug interventionsNot AvailableNot Availablerecruiting
NCT00762255
A Phase I Trial of Vorinostat in Combination With Bevacizumab & Irinotecan in Recurrent Glioblastomatreatment1completed
NCT04289155
Individual Patient Compassionate Use of GX-I7No drug interventionsNot AvailableNot Availableno_longer_available
NCT05700955
Neoadjuvant Chemoimmunotherapy in Recurrent Glioblastomatreatment1recruiting
NCT04121455
Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patientstreatment1 / 2active_not_recruiting
NCT06118723
The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)No drug interventionsNot AvailableNot Availablerecruiting
NCT05168423
CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBMNo drug interventionstreatment1recruiting
NCT05683808
Venous Thromboembolism Prevention in Outpatients With Gliomasupportive_care2not_yet_recruiting
NCT03055208
Early Stereotactic Gamma Knife Radiosurgery to Residual Tumor After Surgery of Newly Diagnosed GlioblastomaNo drug interventionstreatmentNot Availablesuspended
NCT03152708
CAN008 Biomarker CD95 Ligand and CpG2 Methylation in Chinese Patients With GlioblastomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01880008
Evaluation of FLT PET and MRI as Imaging Biomarkers of Early Treatment Response in Patients With GlioblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05218408
CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Typetreatment1 / 2withdrawn
NCT03587038
OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy for Newly Diagnosed Glioblastomatreatment1active_not_recruiting
NCT06146738
The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)No drug interventionsNot AvailableNot Availablerecruiting
NCT00171938
Open-label Trial of Imatinib Mesylate in Patients With Unresectable Recurrent Glioblastoma Multiforme Expressing PDGFR (Platelet Derived Growth Factor Receptors)treatment2terminated
NCT03115138
Evaluation of Circulating Tumor DNA as a Theranostic Marker in the Management of Glioblastomas.No drug interventionsotherNot Availableterminated
NCT06469138
A Phase 1 Study to Investigate 14C-bemcentinib Following Single Oral Administration in Healthy Male Subjectstreatment1completed
NCT01860638
A Comparison of Continuous Bevacizumab (Avastin) Treatment or Placebo in Addition to Lomustine Followed by Standard of Care After Disease Progression in Participants With Glioblastomatreatment2completed
NCT01413438
Bevacizumab With or Without Surgery for Adult GlioblastomasNo drug interventionstreatment2withdrawn
NCT00612638
Ph. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic Gliomastreatment1completed
NCT02718443
VXM01 Phase I Pilot Study in Patients With Operable Recurrence of a Glioblastomatreatment1completed
NCT03374943
A Trial of KB004 in Patients With GlioblastomaNo drug interventionstreatment1completed
NCT00672243
Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiformetreatment2completed
NCT02905643
Discerning Pseudoprogression vs True Tumor Growth in GBMsNo drug interventionsNot AvailableNot Availableterminated
NCT05173623
Trial of Dichloroacetate in Glioblastomatreatment2not_yet_recruiting
NCT02661113
Dasatinib Plus Radiation Therapy/Temozolomide in Newly-Diagnosed Glioblastoma: Phase IItreatment2withdrawn
NCT02671981
Concurrent Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent GlioblastomaNo drug interventionstreatment2recruiting
NCT03538587
Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their CaregiversNo drug interventionssupportive_careNot Availablecompleted
NCT00936052
Hyperbaric Hyperoxygenation With Radiotherapy and Temozolomide in Adults With Newly Diagnosed GlioblastomaNo drug interventionstreatment2unknown_status
NCT03903419
Feasibility Study of 68Ga-PSMA PET-CT and 18F-FDOPA PET-CT in Glioblastoma's PatientsNo drug interventionsdiagnosticNot Availableunknown_status
NCT01102595
Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastomatreatment2completed
NCT01339039
Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Gliomatreatment1terminated
NCT06617208
Prognostic IntraOperative Biomarkers IdeNtification in Tumor RElatEd SuRgeryNo drug interventionsdevice_feasibilityNot Availablenot_yet_recruiting
NCT02046187
Ketogenic Diet With Radiation and Chemotherapy for Newly Diagnosed Glioblastomatreatment1 / 2terminated
NCT03867123
A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patientstreatment1completed
NCT05911230
Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain MetastasesNo drug interventionsdiagnosticNot Availablerecruiting
NCT05431348
Effect of stRess and exeRcize on the Outcome After Chemo-RadiationNo drug interventionsNot AvailableNot Availablerecruiting
NCT02758366
Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Gliomatreatment2terminated
NCT02795364
Study About the Validity of MRS-guided Resection on Prognosis High-grade Glioma GliomasNo drug interventionstreatmentNot Availableunknown_status
NCT01663012
Phase II NKTR-102 In Bevacizumab-Resistant High Grade Gliomatreatment2completed
NCT00107003
GW572016 to Treat Recurrent Malignant Brain Tumorstreatment2completed
NCT05973903
Lenvatinib, Pembrolizumab, and Tumor Treating Fields (TTFields) for Second-line Treatment of Glioblastomatreatment1 / 2not_yet_recruiting
NCT01856933
BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM)No drug interventionstreatment2completed
NCT05086497
WBSI Guided Personalized Delivery of TTFieldsNo drug interventionsdiagnosticNot Availablerecruiting
NCT04115761
Evaluate the Efficacy and Safety of ADCV01 as an Add-On Treatment for Primary Glioblastoma Multiforme (GBM) PatientsNo drug interventionstreatment2unknown_status
NCT03746288
To Evaluate the Efficacy and Safety of CAN008 Combined With Re-irradiation (rRT) for Treating Patients With Recurrent Glioblastoma (GBM)treatment2unknown_status
NCT06039709
Sonodynamic Therapy in Patients With Recurrent GBMtreatment1recruiting
NCT03367715
Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastomatreatment2completed
NCT01238237
Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AAtreatment1completed
NCT03005132
Integrative Analysis of Human Glioblastoma MultiformeNo drug interventionsNot AvailableNot Availablerecruiting
NCT01756352
FET-PET for Evaluation of Response of Recurrent GBM to Avastindiagnostic2completed
NCT01205334
Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma MultiformeNo drug interventionstreatment1 / 2terminated
NCT00591058
Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Gliomatreatment1unknown_status
NCT01124539
Study of AR-67 in Adult Patients With Recurrence of Glioblastoma Multiforme (GBM) or Gliosarcomatreatment2unknown_status
NCT02623231
The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patientssupportive_care2 / 3unknown_status
NCT06396481
Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant GliomaNo drug interventionstreatment0not_yet_recruiting
NCT03758014
Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Grade IV GBM Patientstreatment2 / 3unknown_status
NCT06092255
A Study of SVZ Irradiation With Postoperative Radiotherapy in Patients With GBM.No drug interventionstreatmentNot Availablerecruiting
NCT00683761
A Study of 131I-TM601 in Adults With Recurrent Malignant GliomaNo drug interventionstreatment1 / 2unknown_status
NCT06538428
Methylation Patterns of the NUPR1, MGMT, NDRG2, and GLI1 Genes and Their Impact on Therapeutic Outcome of GBM PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00114309
131-I-TM-601 Study in Adults With Recurrent High-Grade Gliomatreatment2unknown_status
NCT06439849
Single Patient Compassionate Use / Expanded Access L-S-Gboxin (Lyophilized Form of S-Gboxin) for the Treatment of Diffuse Midline GliomaNot AvailableNot Availableno_longer_available
NCT02146066
Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221Not AvailableNot Availableavailable