Neuroblastoma (NB) (DBCOND0089674)

Identifiers

Synonyms
Neuroblastoma CNS / Neuroblastomas / Neuroblastoma / Neuroblastoma (morphologic abnormality) / Neuroblastoma NOS / Neuroblastoma (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Etoposide
A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Iobenguane sulfate I-123
For use in the diagnostic imaging of adrenergically inervated tissues for the purposes of detecting metastatic pheochromocytoma or neuroblastoma [FDA Label]. Also used to assess the sympathetic inervation of the...
Isotretinoin
A retinoid used to treat severe recalcitrant acne.
Vincristine
A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03434262
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumorstreatment1completed
NCT03189706
Study of Chemoimmunotherapy for High-Risk Neuroblastomatreatment0active_not_recruiting
NCT00180947
Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapsetreatment2unknown_status
NCT00695279
Long Term Follow Up Of Patients Who Have Received Gene Therapy Or Gene Marked ProductsNo drug interventionsNot AvailableNot Availablecompleted
NCT01005654
Prospective Comprehensive Molecular Analysis of Endocrine NeoplasmsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01109394
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological StudiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02176967
Response and Biology-Based Risk Factor-Guided Therapy in Treating Younger Patients With Non-high Risk Neuroblastomatreatment3active_not_recruiting
NCT02245997
Local Control With Reduced-dose Radiotherapy for High-Risk NeuroblastomaNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03126916
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)treatment3active_not_recruiting
NCT03721068
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcomatreatment1recruiting
NCT04385277
Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)treatment2active_not_recruiting
NCT04851119
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumorstreatment1 / 2recruiting
NCT06104488
A Study of Avutometinib for People With Solid Tumor Cancerstreatment1recruiting
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)treatment1 / 2recruiting
NCT06638931
Agnostic Therapy in Rare Solid Tumorstreatment2recruiting
NCT01875601
NK White Blood Cells and Interleukin in Children and Young Adults With Advanced Solid Tumorstreatment1completed
NCT02508038
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumorstreatment1suspended
NCT06172296
Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastomatreatment3recruiting
NCT06631391
Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma.treatment1not_yet_recruiting
NCT00107289
Iodine I 131 Metaiodobenzylguanidine in Treating Patients with Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paragangliomatreatment2recruiting
NCT04724369
Open-Label Study of 18F-mFBG for Imaging Neuroblastomadiagnostic3completed
NCT05429502
Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumorstreatment1 / 2recruiting
NCT06233903
18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous Systemdiagnostic2not_yet_recruiting
NCT04936529
A Study of a Vaccine in Combination with Β-glucan and GM-CSF in People with Neuroblastomatreatment2recruiting
NCT06625190
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumorstreatment1 / 2not_yet_recruiting
NCT04753658
Real World Data Collection Pediatric Neuroblastoma Treated With LorlatinibNot AvailableNot Availableterminated
NCT04947501
A Study of N9 Chemotherapy in Children with Neuroblastomatreatment0recruiting
NCT05135975
A Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid Tumorstreatment2recruiting
NCT06057948
A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastomatreatment2recruiting
NCT06528496
N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastomatreatment2recruiting
NCT00003203
Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumorstreatment2completed
NCT00601003
Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastomatreatment2completed
NCT03033303
A Study of the Effect of Hu3F8/GM-CSF Immunotherapy Plus Isotretinoin in Patients in First Remission of High-Risk Neuroblastomatreatment2active_not_recruiting
NCT00002803
Combination Chemotherapy or Observation Following Surgery in Treating Infants With Neuroblastomatreatment2completed
NCT01962103
Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumorstreatment1 / 2completed
NCT00578864
Protracted Etoposide During Induction Therapy for High Risk Neuroblastomatreatment2completed
NCT00486564
Safety Study of Nifurtimox for Relapsed or Refractory Neuroblastomatreatment1completed
NCT05302921
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumorstreatment2active_not_recruiting
NCT02605421
Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastomatreatment2recruiting
NCT03496402
Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO)No drug interventionsotherNot Availablerecruiting
NCT00293384
Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplantsupportive_careNot Availablecompleted
NCT00311584
Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastomatreatment2completed
NCT00659984
N2007-01: Ultratrace™ Iobenguane I 131 in Patients With Relapsed/Refractory High-Risk Neuroblastomatreatment2completed
NCT01701479
Long Term Continuous Infusion ch14.18/CHO Plus s.c. Aldesleukin (IL-2)treatment1 / 2unknown_status
NCT00471679
Ethanol-Lock Treatment in Preventing Central Venous Catheter Infections in Patients With High-Risk Neuroblastomasupportive_care1completed
NCT00276679
Temozolomide in Treating Young Patients With High-Risk Relapsed or Refractory Neuroblastomatreatment2completed
NCT01445379
Phase I Study of Ipilimumab (Anti-CTLA-4) in Children and Adolescents With Treatment-Resistant Cancertreatment1completed
NCT02765243
Anti-GD2 4th Generation CART Cells Targeting Refractory and/or Recurrent NeuroblastomaNo drug interventionstreatment1completed
NCT01838187
Expanded Access Protocol Using 131I-MIBG Therapy +/- Vorinostat for Refractory Neuroblastoma, Pheochromocytoma, or ParagangliomaNot AvailableNot Availableno_longer_available
NCT01916187
Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastomatreatment1withdrawn
NCT00003887
Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell TransplantationNo drug interventionstreatment2completed
NCT03294954
GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With NeuroblastomaNo drug interventionstreatment1recruiting
NCT00082654
Study of the Emotional Needs of Caregivers of Stem Cell Transplantation PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05990751
Multi-modular Chimeric Antigen Receptor Targeting GD2 in NeuroblastomaNo drug interventionstreatment1recruiting
NCT01525251
Nurse Case Manager Model on Neuroblastoma Caregiver's UncertaintyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00793351
Reduced Intensity Stem Cell Transplantation in Children With Relapsed Neuroblastoma After Autologous TransplantationNo drug interventionstreatment2completed
NCT00093353
N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastomatreatment1completed
NCT02909777
Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphomatreatment1active_not_recruiting
NCT02075177
Expanded Access Study of Fenretinide Lym-X-Sorb Plus Ketoconazole in NeuroblastomaNot AvailableNot Availableno_longer_available
NCT04337177
Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumorstreatment1recruiting
NCT04837547
PEACH TRIAL- Precision Medicine and Adoptive Cellular TherapyNo drug interventionstreatment1recruiting
NCT01592045
ch14.18 Pharmacokinetic Study in High-risk Neuroblastomatreatment1 / 2completed
NCT00793845
Tandem High-dose Chemotherapy and Autologous Stem Cell Rescue in Patients With High-risk Neuroblastomatreatment2completed
NCT00112645
Donor Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory Solid Tumorstreatment1completed
NCT01058798
The Role of Glycosyltransferases in the Oncogenesis of NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT06574698
Adding Of Naxitamb In Induction Therapy For High Risk NeuroblastomaNot AvailableNot Availablerecruiting
NCT02914405
Phase I Study of 131-I mIBG Followed by Nivolumab & Dinutuximab Beta Antibodies in Children With Relapsed/Refractory Neuroblastomatreatment1recruiting
NCT01183897
3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Primary Refractory Neuroblastoma in Bone MarrowNo drug interventionstreatment2completed
NCT01943097
Evaluation of 18F-dopa and 123I-MIBG Uptake in the Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT02164097
ODSH + ICE Chemotherapy in Pediatric Solid Tumorstreatment1terminated
NCT06071897
Induction Chemoimmunotherapy for Patients With High-risk NeuroblastomaNo drug interventionstreatment3recruiting
NCT01163383
131-I-MIBG Therapy for Refractory Neuroblastoma, Expanded Access ProtocolNot AvailableNot Availableavailable
NCT00946283
Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic SyndromeNo drug interventionssupportive_careNot Availableterminated
NCT02536183
A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumorstreatment1terminated
NCT00003661
Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancertreatment2completed
NCT00025428
Combination Chemotherapy Before Surgery in Treating Children With Localized Neuroblastomatreatment3completed
NCT02780128
Next Generation Personalized Neuroblastoma Therapytreatment1terminated
NCT00040911
Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagnosed Childhood Sarcoma, Neuroblastoma, Nasopharyngeal Cancer, Germ Cell Tumors, or Hodgkin LymphomaNo drug interventionssupportive_careNot Availablecompleted
NCT00064311
Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantationsupportive_care1 / 2completed
NCT00109993
Campath-1H + FK506 and Methylprednisolone for GVHDsupportive_care2completed
NCT00024193
Chemotherapy and Surgery Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Neuroblastomatreatment2unknown_status
NCT01059071
Safety Study for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With Etoposidetreatment1completed
NCT04029688
A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumorstreatment1 / 2completed
NCT02624388
Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)supportive_care2terminated
NCT03107988
NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)treatment1active_not_recruiting
NCT00072488
Whole-Body MRI and Conventional Imaging in Detecting Distant Metastases in Young Patients With Solid Tumors or LymphomaNo drug interventionsdiagnosticNot Availableunknown_status
NCT02439788
3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL KILLER T-CELLS FOR NEUROBLASTOMAtreatment1withdrawn
NCT00206388
Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvementtreatment1completed
NCT00003107
Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumorstreatment1completed
NCT02169609
Safety Study of Dinutuximab Combined With Immunotherapy to Treat Neuroblastomatreatment2completed
NCT02745756
A Combined Cell Therapy Approach to the Treatment of NeuroblastomaNo drug interventionstreatment1withdrawn
NCT02163356
Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant Neuroblastomatreatment1terminated
NCT00002485
Development of Strategies to Increase Enrollment in Clinical Trials for Children With CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT04909515
Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GMCSF) and Isotretinoin for Consolidation of Patients With High-Risk Neuroblastoma in First Remission.treatment2withdrawn
NCT00002515
Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Rare Cancertreatment2completed
NCT04253015
A Post-Authorisation Safety Study Patient Registry of Patients With Neuroblastoma Being Treated With Dinutuximab BetaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00003737
Rebeccamycin Analog in Treating Children With Relapsed or Refractory Neuroblastomatreatment2completed
NCT02035137
131I-MIBG Alone VS. 131I-MIBG With Vincristine and Irinotecan VS131I-MIBG With Vorinostattreatment2completed
NCT05918432
Determining Patterns In Study Experiences of Neuroblastoma PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02162732
Molecular-Guided Therapy for Childhood CancerNo drug interventionstreatmentNot Availablecompleted
NCT06296732
Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors StratificationNo drug interventionsNot AvailableNot Availablerecruiting
NCT00005952
Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumorstreatment1 / 2completed
NCT01953900
iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastomatreatment1active_not_recruiting
NCT01510600
Studying Biomarkers in Samples From Patients With High-Risk NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00539500
Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastomatreatment2 / 3terminated
NCT00070200
Induction Chemotherapy Using Cyclophosphamide and Topotecan in Treating Patients Who Are Undergoing Autologous Peripheral Stem Cell Transplantation for Newly Diagnosed or Progressive Neuroblastomatreatment1completed
NCT00357500
Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancertreatment2completed
NCT00036959
ABT-751 in Treating Young Patients With Refractory Solid Tumorstreatment1completed
NCT01583842
124I-Metaiodobenzylguanidine (MIBG) PET/CT Diagnostic Imaging and Dosimetry for Patients With Neuroblastoma: A Pilot Studydiagnostic0terminated
NCT03545542
Investigating the Microbiome and Volatile Organic Compound Profile of Children With NeuroblastomaNo drug interventionsbasic_scienceNot Availableunknown_status
NCT04903899
177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastomatreatment2recruiting
NCT00808899
Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastomatreatment2terminated
NCT00900406
Collecting and Storing Tissue and DNA Samples From Patients Undergoing a Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availablecompleted
NCT02615106
Anti-angiogenetic Therapy With Radiotherapy for Pediatric Neuroblastomatreatment2unknown_status
NCT02076906
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid TumorsNo drug interventionstreatment1active_not_recruiting
NCT00025649
Combination Chemotherapy Followed by Surgery and Peripheral Stem Cell or Bone Marrow Transplantation in Treating Infants With Newly Diagnosed Neuroblastomatreatment2completed
NCT04730349
A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancertreatment1 / 2terminated
NCT01373736
123I-MIBG Scintigraphy in Patients Being Evaluated for Neuroendocrine TumorsNo drug interventionsdiagnostic3unknown_status
NCT01313936
High-Dose 131I-MIBG Therapy Combined With Vincristine and Five Days of Irinotecan for Resistant/Relapsed Neuroblastomatreatment1completed
NCT02013336
Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumorstreatment1unknown_status
NCT00007813
Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumorstreatment1completed
NCT00790413
Haploidentical Stem Cell Transplantation in Neuroblastomatreatment0unknown_status
NCT01518413
Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumorstreatment1completed
NCT00053118
Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancertreatment1completed
NCT00526318
Combination Chemotherapy Followed by Stem Cell Transplant and Isotretinoin in Treating Young Patients With High-Risk NeuroblastomatreatmentNot Availableunknown_status
NCT04106219
A Study of LY3295668 Erbumine in Participants With Relapsed/Refractory Neuroblastomatreatment1active_not_recruiting
NCT01121419
The Role of IMP3 Expression in Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT05781919
Use of Virtual Reality for Surgical Planning in NeuroblastomaNo drug interventionstreatmentNot Availablerecruiting
NCT00030719
Combination Chemotherapy With or Without Filgrastim Before Surgery, High-Dose Chemotherapy, and Radiation Therapy Followed by Isotretinoin With or Without Monoclonal Antibody in Treating Patients With Neuroblastomatreatment3unknown_status
NCT06450041
NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trialtreatment2not_yet_recruiting
NCT02982941
Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumorstreatment1completed
NCT04559217
68Ga-DOTATATE Neuroblastoma Imaging Pilotdiagnostic2recruiting
NCT00002634
Chemotherapy, Radiation Therapy, Immunotherapy, and Bone Marrow Transplantation in Treating Patients With Neuroblastomatreatment2completed
NCT06275334
Dinutuximab Beta at the HUS and the Toulouse OncopoleNo drug interventionsNot AvailableNot Availablerecruiting
NCT00324324
Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplantsupportive_care3terminated
NCT02924324
Local Injection of Pain Medication to Reduce Pain After Bone Marrow Procedures in Pediatric Neuroblastoma PatientstreatmentNot Availablecompleted
NCT01183416
High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantationtreatment2completed
NCT00743496
A Phase I Trial Of The Humanized Anti-GD2 Antibody In Children And Adolescents With Neuroblastoma, Osteosarcoma, Ewing Sarcoma and MelanomaNo drug interventionstreatment1completed
NCT00644696
Study of Irinotecan and Bortezomib in Children With Recurrent/Refractory Neuroblastomatreatment1completed
NCT00590096
I-123-MIBG for Imaging of Neuroblastoma and PheochromocytomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01987596
Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancersupportive_care3terminated
NCT01462396
Allogeneic Stem Cell Transplantation for Advanced Neuroblastoma Using MHC Mismatched Related DonorsNo drug interventionsdevice_feasibility1completed
NCT05826158
18F-mFBG LAFOV PET/CT Compared to 123I-mIBG Scintigraphy SPECT/CT for Evaluation of Children With NeuroblastomaNo drug interventionsdiagnostic3recruiting
NCT00072358
Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastomatreatment2completed
NCT00132158
ZD1839 and Oral Irinotecan in Treating Young Patients With Refractory Solid Tumorstreatment1completed
NCT00089258
Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatmenttreatment2completed
NCT00001335
New Therapeutic Strategies for Patients With Ewing's Sarcoma Family of Tumors, High Risk Rhabdomyosarcoma, and Neuroblastomatreatment2completed
NCT01331135
Aflac ST0901 CHOANOME - Sirolimus in Solid Tumorstreatment1completed
NCT00960063
A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)treatment1terminated
NCT00048386
Neuroblastoma Vaccine for Treatment of High-Risk Neuroblastoma After ChemotherapyNo drug interventionstreatment1completed
NCT05027386
Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastomatreatment2recruiting
NCT00703222
A Phase I/II Study Of Immunization With Lymphotactin And Interleukin 2 Gene Modified Neuroblastoma Tumor CellsNo drug interventionstreatment1 / 2active_not_recruiting
NCT00084422
N2001-03: CEP-701 in Treating Young Patients With Recurrent or Refractory High-Risk Neuroblastomatreatment1completed
NCT00003122
Surgery in Treating Patients With NeuroblastomaNo drug interventionstreatment2unknown_status
NCT01869725
Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CTdiagnostic2completed
NCT00003425
Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotecttreatment1 / 2completed
NCT00002825
Docetaxel in Treating Children With Recurrent Solid Tumorstreatment2completed
NCT00085930
Blood T-Cells and EBV Specific CTLs Expressing GD-2 Specific Chimeric T Cell Receptors to Neuroblastoma Patientstreatment1active_not_recruiting
NCT00646230
N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastomatreatment1completed
NCT02307630
PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot StudyNo drug interventionsdiagnosticNot Availableactive_not_recruiting
NCT00202930
Use of Rituximab in Opsoclonus-Myoclonus in Children With Neuroblastomatreatment2terminated
NCT01493830
Biomarkers in Tumor Samples From Younger Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01553448
Studying Gene Expression in Samples From Younger Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02298348
Sorafenib and Cyclophosphamide/Topotecan in Patients With Relapsed and Refractory Neuroblastomatreatment1active_not_recruiting
NCT00798148
131I-MIBG With Myeloablative Chemotherapy and Autologous Stem Cell Transplantation for the Treatment of High-risk Neuroblastomatreatment1 / 2unknown_status
NCT00436657
Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancertreatment1completed
NCT03236857
A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignanciestreatment1completed
NCT00004157
Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumorstreatment2completed
NCT00118326
Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Diseasetreatment1 / 2completed
NCT01757626
Combination Therapy of Antibody Hu3F8 With Granulocyte- Macrophage Colony Stimulating Factor (GM-CSF) in Patients With Relapsed/Refractory High-Risk Neuroblastomatreatment1 / 2active_not_recruiting
NCT01095926
Pharmacokinetic Study of Doxorubicin in Children With Cancertreatment2completed
NCT03686566
Pediatric Solid Tumor Metabolism [A Prospective Study Exploring Metabolism of Solid Tumors in Pediatrics]No drug interventionsNot AvailableNot Availablecompleted
NCT00098865
Thalidomide and Temozolomide in Relapsed or Progressive CNS Disease or Neuroblastomatreatment2completed
NCT01619865
Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumorsdiagnostic1 / 2completed
NCT00939965
Isotretinoin in Treating Young Patients With High-Risk NeuroblastomatreatmentNot Availableunknown_status
NCT06190574
Diagnostic Efficacy and Prognostic Value of 18F-FDG PET/CT (MR) in Pediatric Solid BlastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT03541720
18F-Fluorodopamine PET Studies of Neuroblastoma and PheochromocytomaNo drug interventionsdiagnostic0recruiting
NCT00918320
Studies of Temozolomide in Combination With Topotecan in Refractory and Relapsed Paediatric Solid Tumourstreatment2completed
NCT00907920
Studying Tumor Samples From Young Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT02641782
NB2013-HR German (GPOH) / Dutch (DCOG) Trialtreatment2terminated
NCT00336531
Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantationprevention4completed
NCT00410631
Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastomatreatment3unknown_status
NCT00931931
HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid TumorsNo drug interventionstreatment1completed
NCT04023331
67Cu-SARTATE™ Peptide Receptor Radionuclide Therapy Administered to Pediatric Patients With High-Risk, Relapsed, Refractory Neuroblastomatreatment1 / 2recruiting
NCT00080873
Traumeel® S in Preventing and Treating Mucositis in Young Patients Undergoing Stem Cell TransplantationNo drug interventionssupportive_careNot Availablecompleted
NCT01492673
Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastomatreatment2completed
NCT00020527
Caspofungin Acetate in Treating Children With Fever and Neutropeniasupportive_careNot Availablecompleted
NCT05303727
Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastomatreatment2not_yet_recruiting
NCT00450827
Iodine I 131 Monoclonal Antibody 3F8 and Bevacizumab in Treating Patients With Relapsed or Refractory Neuroblastomatreatment1completed
NCT01747876
Study of Safety and Efficacy in Patients With Malignant Rhabdoid Tumors (MRT) and Neuroblastomatreatment1terminated
NCT00716976
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancysupportive_care3completed
NCT00416676
Combination Chemotherapy and Surgery With or Without Radiation Therapy in Treating Patients With Stage 2 or Stage 3 Neuroblastomatreatment3unknown_status
NCT00911560
Bivalent Vaccine With Escalating Doses of the Immunological Adjuvant OPT-821, in Combination With Oral β-glucan for High-Risk Neuroblastomatreatment1 / 2active_not_recruiting
NCT02100891
Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumorstreatment2completed
NCT03478462
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcomatreatment1active_not_recruiting
NCT02441062
Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumorsdiagnostic2completed
NCT03709680
Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumorstreatment1 / 2active_not_recruiting
NCT05192980
SIOPEN BIOPORTAL, An International Registry Linked to a Virtual Biobank for Patients With Peripheral Neuroblastic TumoursNo drug interventionsotherNot Availablerecruiting
NCT00006480
Biological Therapy and Gene Therapy in Treating Children With Recurrent or Refractory Neuroblastomatreatment1completed
NCT01222780
To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancertreatment1completed
NCT03042429
Combination Chemotherapy Followed by Stem Cell Transplant in High-risk Neuroblastoma Patientstreatment3completed
NCT01048892
Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Featurestreatment1completed
NCT01576692
Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastomatreatment1completed
NCT02679144
Neuroblastoma Maintenance Therapy Trialprevention2recruiting
NCT03015844
A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic PheochromocytomaNot AvailableNot Availableavailable
NCT00002740
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastomatreatment1completed
NCT00303940
Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumorstreatment1completed
NCT03581240
An Intermediate Expanded Use Trial of DFMONot AvailableNot Availableavailable
NCT00392340
Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 Neuroblastomatreatment2unknown_status
NCT00947167
A Phase II Study of Pertuzumab and Erlotinib for Metastatic or Unresectable Neuroendocrine Tumorstreatment2terminated
NCT03332667
MIBG With Dinutuximab +/- Vorinostattreatment1active_not_recruiting
NCT01638572
Exploring the Possibility to Use Glycosyltransferase as a Prognosis Marker of NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00428272
HGS-ETR2 to Treat Children With Solid Tumorstreatment1terminated
NCT02868268
Neuroblastoma Precision TrialNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00900068
Blood Samples From Patients on a Clinical Trial to CINV During HSCTNo drug interventionsNot AvailableNot Availableterminated
NCT00017368
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastomatreatment2completed
NCT01807468
Haploidentical Stem Cell Transplantation and NK Cell Therapy in Patients With High-risk Solid TumorsNo drug interventionstreatment2unknown_status
NCT03209869
Treatment of Relapsed or Refractory Neuroblastoma and Osteosarcoma With Expanded Haploidentical NK Cells and Hu14.18-IL2treatment1withdrawn
NCT02130869
A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomastreatment1completed
NCT00003846
Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive Neuroectodermal Tumorstreatment2completed
NCT00996710
Genomic Structural Variation in Cancer SusceptibilityNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04706910
18F-DOPA II - PET Imaging Optimizationdiagnostic3recruiting
NCT00877110
Anti-GD2 3F8 Antibody and Allogeneic Natural Killer Cells for High-Risk Neuroblastomatreatment1completed
NCT06502210
Identification of New Gene Spliceosomes in NeuroblastomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00670410
Autologous Transplant Followed by Allogeneic Transplant for High Risk Neuroblastomatreatment1terminated
NCT00084695
Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant Diseasestreatment2unknown_status
NCT01192555
Allogeneic Tumor Cell Vaccination With Oral Metronomic Cytoxan in Patients With High-Risk Neuroblastomatreatment1 / 2active_not_recruiting
NCT01114555
Bevacizumab, Irinotecan and Temozolomide for Relapsed or Refractory Neuroblastomatreatment2completed
NCT00898755
Collecting and Storing Tissue From Young Patients With CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00005955
Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumorstreatment2completed
NCT00287950
Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Infants With NeuroblastomatreatmentNot Availableunknown_status
NCT02457650
T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignanciestreatment1unknown_status
NCT00049023
Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid TumorsNo drug interventionstreatment1completed
NCT00003408
Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancertreatment2completed
NCT00582608
Tumor Detection Using Iodine-131-Labeled Monoclonal Antibody 8H9No drug interventionsdiagnosticNot Availableterminated
NCT01802138
A Pilot Study of Activated T Cell Therapy for Refractory/Relapsed NeuroblastomaNo drug interventionstreatmentNot Availablecompleted
NCT01319838
Aflac ST1001 Prolonged Isotretinointreatment1withdrawn
NCT00002543
Gallium Nitrate in Treating Children With Brain Tumor, Neuroblastoma, Rhabdomyosarcoma, Non-Hodgkin's Lymphoma, or Refractory Solid Tumorstreatment1completed
NCT04637503
4SCAR-T Therapy Targeting GD2, PSMA and CD276 for Treating NeuroblastomaNo drug interventionstreatment1 / 2unknown_status
NCT05400603
Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcomatreatment1recruiting
NCT01526603
High Dose Chemotherapy and Autologous Transplant for NeuroblastomaotherNot Availablecompleted
NCT03503864
Phase II Study of Combined Chemotherapy With Arsenic Trioxide in Stage 4/M Neuroblastomatreatment2recruiting
NCT02030964
N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecantreatment1active_not_recruiting
NCT04864821
Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid TumorNo drug interventionstreatment0unknown_status
NCT04897321
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)treatment1recruiting
NCT02311621
Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01No drug interventionstreatment1active_not_recruiting
NCT03275402
131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastasestreatment2 / 3terminated
NCT00002802
Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastomatreatment3completed
NCT00006102
Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphomatreatment2completed
NCT01404702
Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastomatreatment1terminated
NCT02444884
MLN8237 to Treat Children With Relapsed/Refractory Solid Tumorstreatment1completed
NCT01183884
3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of Second or Greater Remission of High-Risk Neuroblastomatreatment2terminated
NCT01169584
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patientstreatment1completed
NCT00003484
Radiolabeled Monoclonal Antibody Therapy After Radiation Therapy in Treating Patients With Primary Brain Tumorstreatment1completed
NCT01355679
Molecular Guided Therapy for Refractory or Recurrent NeuroblastomaNo drug interventionsdiagnosticNot Availablecompleted
NCT06000787
MCT for the Harvard/UCSF ROBIN CenterNo drug interventionsbasic_scienceNot Availablerecruiting
NCT03013387
Dosimetry Guided PRRT With 90Y-DOTATOCtreatment2withdrawn
NCT02933333
G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumortreatment4unknown_status
NCT01520233
Gene Expression in Predicting Outcome in Samples From Patients With High-Risk NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00407433
Clinical Studies of Gemcitabine-Oxaliplatintreatment2completed
NCT02557854
HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumorstreatment1withdrawn
NCT01598454
Use of Racotumomab in Patients With Pediatric Tumors Expressing N-glycolylated Gangliosidestreatment1completed
NCT00923351
Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or NeuroblastomaNo drug interventionstreatment1 / 2completed
NCT03966651
A Clinical Study Evaluating the Safety of Peptide Receptor Radionuclide Therapy (PRRT) With 177Lu-DOTA0-Tyr3-Octreotate in Children With Refractory or Recurrent Neuroblastoma Expressing Somatostatin Receptors.treatment1recruiting
NCT01625351
A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomastreatment1completed
NCT00417053
Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma Who Are Undergoing Surgery With or Without Autologous Bone Marrow or Peripheral Stem Cell Transplanttreatment3unknown_status
NCT00509353
N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastomatreatment1completed
NCT06485947
Study Combining Dinutuximab Beta With Two Chemotherapy Regimens in Neuroblastomatreatment1not_yet_recruiting
NCT00840047
Methionine PET/CT Studies In Patients With Cancerdiagnostic2recruiting
NCT00089245
Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancertreatment1terminated
NCT01853345
iCAT for Recurrent/Refractory/HR Solid TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00782145
A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their FamiliesNo drug interventionssupportive_care3completed
NCT06335745
PediCARE Health Equity Intervention in High-Risk NeuroblastomaNo drug interventionssupportive_careNot Availablewithdrawn
NCT01308905
Monitor Response to Treatment in Neuroblastoma Using 3&Apos;-Deoxy-3&Apos;-Fluorothymidine- Positron Emission Tomography (FLT-PET)No drug interventionsdiagnosticNot Availableunknown_status
NCT00281905
Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumorstreatment2unknown_status
NCT03373097
Anti-GD2 CAR T Cells in Pediatric Patients Affected by High Risk and/or Relapsed/Refractory Neuroblastoma or Other GD2-positive Solid TumorsNo drug interventionstreatment1 / 2recruiting
NCT05421897
Rapid Administration Pilot for Infusing Dinutuximabtreatment4recruiting
NCT00025597
Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastoma.treatment2completed
NCT02998983
Racotumomab in Patients With High-risk Neuroblastomatreatment2completed
NCT00010283
Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colonsupportive_care1 / 2completed
NCT00003461
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain TumorsNo drug interventionstreatment1 / 2completed
NCT03583528
DOTATOC PET/CT for Imaging NET PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03458728
Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patientstreatment1 / 2terminated
NCT01132911
A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomastreatment1completed
NCT00037011
Beta-Glucan and Monoclonal Antibody in Treating Patients With Metastatic Neuroblastomatreatment1completed
NCT00003093
Combination Chemotherapy in Treating Children With Neuroblastomatreatment3completed
NCT02693171
Post-Marketing Assessment of Immunogenicity and Safety of Unituxin® in High-Risk Neuroblastoma PatientsNot AvailableNot Availableterminated
NCT04474678
Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")No drug interventionstreatmentNot Availablecompleted
NCT00005978
N99-01: Combination Chemotherapy, Radiation Therapy, and Stem Cell Transplantation in Treating Patients With Neuroblastomatreatment1completed
NCT02559778
Pediatric Precision Laboratory Advanced Neuroblastoma Therapytreatment2recruiting
NCT04483778
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adultstreatment1active_not_recruiting
NCT00004188
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastomatreatment3completed
NCT04040088
An Investigational Scan (68Ga-DOTATATE PET/CT) in Diagnosing Pediatric Metastatic Neuroendocrine Tumorsdiagnostic0recruiting
NCT00450307
Monoclonal Antibody 3F8 and GM-CSF in Treating Young Patients With High-Risk, Refractory or Relapsed Neuroblastomatreatment1completed
NCT03860207
Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma, Osteosarcoma and Other Solid Tumor Cancerstreatment1 / 2terminated
NCT00698009
Haploidentical Natural Killer (NK) Cells in Patients With Relapsed or Refractory Neuroblastomatreatment2terminated
NCT00001509
A Phase II Trial of All-Trans-Retinoic Acid in Combination With Interferon-Alpha 2a in Children With Recurrent Neuroblastoma or Wilms' Tumortreatment2completed
NCT00187109
Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapytreatment1 / 2completed
NCT02337309
SF1126 for Patients With Relapsed or Refractory Neuroblastomatreatment1terminated
NCT00101309
Vaccine Therapy and Interleukin-2 in Treating Young Patients With Relapsed or Refractory Ewing's Sarcoma or Neuroblastomatreatment1unknown_status
NCT02431715
18F-FDOPA PET in Neuroendocrine TumoursNo drug interventionsNot AvailableNot Availableno_longer_available
NCT00874315
Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refractory High-Risk NBL.treatment2withdrawn
NCT01174537
New Castle Disease Virus (NDV) in Glioblastoma Multiforme (GBM), Sarcoma and NeuroblastomaNo drug interventionstreatment1 / 2withdrawn
NCT05770037
DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Teenage/Young Adults (TYA) and Paediatric Patients With ALK Positive Cancerstreatment2 / 3recruiting
NCT01822652
3rd Generation GD-2 Chimeric Antigen Receptor and iCaspase Suicide Safety Switch, Neuroblastoma, GRAINtreatment1active_not_recruiting
NCT00608452
Prevalence+Significance of Paraneoplastic Autoantibodies in Many CancersNo drug interventionsNot AvailableNot Availablecompleted
NCT01587300
Neuroblastoma Biology StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01125800
A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MBtreatment1 / 2completed
NCT01353300
Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT05782959
Phase 1 Study of BCD-245 in Subjects With NeuroblastomaNo drug interventionstreatment1recruiting
NCT03561259
A Study of Therapeutic Iobenguane (131-I) and Vorinostat for Recurrent or Progressive High-Risk Neuroblastoma Subjectstreatment2recruiting
NCT00416559
Observation of Young Patients With Localized Neuroblastoma Who Have Undergone Surgery OnlyNo drug interventionssupportive_care2unknown_status
NCT00066599
Voriconazole in Preventing Fungal Infections in Children With Neutropenia After Chemotherapysupportive_care2completed
NCT05701306
APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumorstreatment1recruiting
NCT00013806
CHP677: I-Metaiodobenzylguanidine (I-MIBG) Therapy for Refractory Neuroblastoma: a Phase II StudyNo drug interventionstreatment2unknown_status
NCT00186849
Therapy for Children With Advanced Stage High Risk Neuroblastomatreatment2completed
NCT00003513
Antineoplaston Therapy in Treating Patients With Metastatic, Recurrent, or Refractory Neuroblastomatreatment2terminated
NCT06013618
Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastomatreatment2recruiting
NCT00293319
131 I-MIBG in Treating Patients With Refractory or Relapsed Neuroblastomatreatment2completed
NCT02786719
High-Risk Neuroblastoma Chemotherapy Without G-CSFtreatmentNot Availablecompleted
NCT01386619
NK DLI in Patients After Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)treatment1 / 2completed
NCT06500819
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid TumorsNo drug interventionstreatment1recruiting
NCT00003119
Surgery in Treating Children With Neuroblastomatreatment3completed
NCT00295919
N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastomatreatment1completed
NCT00003141
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumorstreatment1completed
NCT01589341
Studying Chromosomes in Samples From Younger Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT01482741
Understanding Patient Perspectives on the Risks of Ionizing Radiation Used for Medical ImagingNo drug interventionsNot AvailableNot Availablecompleted
NCT02112617
Phase II Study of Proton Radiation Therapy for NeuroblastomaNo drug interventionstreatmentNot Availablerecruiting
NCT01857934
Therapy for Children With Advanced Stage Neuroblastomatreatment2active_not_recruiting
NCT01419834
Humanized 3F8 Monoclonal Antibody (Hu3F8) in Patients With High-Risk Neuroblastoma and GD2-Positive Tumorstreatment1completed
NCT00003234
Vinorelbine in Treating Children With Recurrent or Refractory Cancerstreatment2completed
NCT00726934
The Effectiveness of the Neutropenic Diet in Pediatric Oncology PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT00503724
Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumorstreatment1completed
NCT01387724
Biomarkers in Blood and Tissue Samples From Patients With Newly Diagnosed NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00349024
Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancersupportive_careNot Availableunknown_status
NCT01704716
High Risk Neuroblastoma Study 1.8 of SIOP-Europe (SIOPEN)treatment3recruiting
NCT03042416
18F-DOPA PET Imaging: an Evaluation of Biodistribution and SafetyNo drug interventionsdiagnostic3completed
NCT00499616
Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastomatreatment3completed
NCT00651716
T Cells in Predicting Acute Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availableterminated
NCT02573896
Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cellstreatment1active_not_recruiting
NCT03382158
International PPB/DICER1 RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT00082758
hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastomatreatment2completed
NCT00002458
Monoclonal Antibody Therapy in Treating Children With Metastatic Neuroblastoma in Second Remissiontreatment2completed
NCT00024258
Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumorstreatment2completed
NCT00083135
N2000-01: Double Infusion of Iodine I 131 Metaiodobenzylguanidine Followed by Autologous Stem Cell Transplantationtreatment1completed
NCT01601535
Study of MLN8237 in Combination With Irinotecan and Temozolomidetreatment1 / 2completed
NCT06047535
Naxitamab and Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) Combined With Isotretinoin for Maintenance Treatment of Patients With High-Risk Neuroblastoma in First Complete Response.prevention4not_yet_recruiting
NCT00005835
N99-02: Melphalan and Buthionine Sulfoximinetreatment1completed
NCT00135135
Therapy for Children With Neuroblastomatreatment2completed
NCT00253435
N2001-02: I-MIBG With Intensive Chemotherapy and Autologous Stem Cell Rescue for High-Risk Neuroblastomatreatment2completed
NCT02864563
Pan-genome Analysis of Neuroblastoma by Comparative Genomic Hybridization and Correlation With Pathology for the Diagnostic and the Prognostic ClassificationNo drug interventionsbasic_scienceNot Availablecompleted
NCT02107963
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults With GD2+ Solid Tumorstreatment1completed
NCT01048086
90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)treatment2withdrawn
NCT00754286
A Randomized Trial of The Effectiveness of Aromatherapy on Chemotherapy Induced Nausea and Vomiting in Children With CancerNo drug interventionssupportive_careNot Availablecompleted
NCT00960739
Iodobenzylguanidine Meta-I131 and Topotecan in Young Patients With Refractory or Relapsed Metastatic Neuroblastomatreatment2completed
NCT01713439
Allogeneic Neuroblastoma Cells for Relapsed/ Refractory Neuroblastoma, CYCHEALLNo drug interventionstreatment1completed
NCT00165139
Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomastreatment2completed
NCT00003022
Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal CancerNo drug interventionstreatment1completed
NCT00017225
Chemotherapy and Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Neuroblastomatreatment2completed
NCT00788125
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumorstreatment1 / 2terminated
NCT01370330
131I-Labeled MIBG for Refractory Neuroblastoma: A Compassionate Use ProtocolNot AvailableNot Availableavailable
NCT02100930
Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk NeuroblastomatreatmentNot Availablecompleted
NCT04308330
Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignanciestreatment1recruiting
NCT00002730
Chemotherapy in Treating Children With Neuroblastomatreatment1completed
NCT02650648
Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastomatreatment1active_not_recruiting
NCT00002748
Gene Therapy in Treating Children With Refractory or Recurrent Neuroblastomatreatment1completed
NCT00410657
Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplantsupportive_care2completed
NCT00885326
N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastomatreatment1completed
NCT00152126
Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and LymphomastreatmentNot Availablecompleted
NCT00003926
Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumorssupportive_care1terminated
NCT00389766
High-Dose Iodine I 131 Metaiodobenzylguanidine, Topotecan, and Peripheral Stem Cell Transplant in Treating Young Patients With Relapsed Stage 4 Neuroblastoma or Primary Resistant High-Risk Neuroblastomatreatment2withdrawn
NCT02395666
Preventative Trial of Difluoromethylornithine (DFMO) in High Risk Patients With Neuroblastoma That is in Remissionprevention2completed
NCT00445965
Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal CancerNo drug interventionstreatment2completed
NCT00001565
Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancytreatment1completed
NCT05069220
18F-MFBG PET/CT in the Evaluation of Neural Crest Tumordiagnostic0recruiting
NCT01483820
Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastomatreatment1 / 2terminated
NCT00801931
Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorderstreatment1 / 2terminated
NCT00276731
Combination Chemotherapy Followed By Surgery With or Without Radiation Therapy in Treating Young Patients With Stage II or Stage III Neuroblastomatreatment3unknown_status
NCT01407731
Protein Expression in Human Neuroblastoma Tumor SamplesNo drug interventionsNot AvailableNot Availablecompleted
NCT00992173
Efficacy and Safety of Ultratrace™ Iobenguane I 131 in Neuroblastomatreatment2withdrawn
NCT00003273
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumortreatment2withdrawn
NCT01288573
A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alonetreatment1 / 2completed
NCT02177773
GA-68 DOTA-TOC of Somatostatin Positive Malignanciesdiagnostic1 / 2terminated
NCT03363373
Naxitamab for High-Risk Neuroblastoma Patients With Primary Refractory Disease or Incomplete Response to Salvage Treatment in Bone and/or Bone Marrowtreatment2recruiting
NCT02308527
Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in Childrentreatment2active_not_recruiting
NCT00405327
A Pilot Study of Tumor Cell Vaccine for High-risk Solid Tumor Patients Following Stem Cell TransplantationNo drug interventionstreatment2completed
NCT01169376
Biomarkers in Young Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT00002560
Monoclonal Antibody Therapy Plus Sargramostin in Treating Patients With Advanced Neuroblastomatreatment2completed
NCT01075360
The Role of Aromatic Hydrocarbon Receptor in the Tumorigenesis of Neuroblastoma and Its Relationship With MYCN ExpressionNo drug interventionsNot AvailableNot Availablecompleted
NCT01119560
Genetic Susceptibility Biomarkers in Children With Neuroblastoma (Also Known as Neuroblastoma Epidemiology in North America [NENA])No drug interventionsNot AvailableNot Availablecompleted
NCT00003191
Fenretinide in Treating Children With Solid Tumorstreatment1completed
NCT01295762
Immunomonitoring of Children With NeuroblastomaNo drug interventionsscreeningNot Availableunknown_status
NCT01241162
Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcomatreatment1completed
NCT00624962
Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid TumorsNo drug interventionssupportive_careNot Availablewithdrawn
NCT00186862
Gene Modified Allogeneic Neuroblastoma Cells For Treatment of Relapsed/Refractory Neuroblastomatreatment1completed
NCT03291080
Oral Liquid 13-cis-retinoic Acid (13-CRA)other1 / 2completed
NCT03517280
Nutritional Status in Neuroblastoma in Sao Paolo, BrazilNo drug interventionsNot AvailableNot Availablecompleted
NCT00026780
Eligibility Screening for a NCI Pediatric Oncology Branch Research StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00944580
A Vaccine Study for High Risk Cancerstreatment1withdrawn
NCT01590680
Expanded Access Protocol Using 131I-MIBGNo drug interventionsNot AvailableNot Availableavailable
NCT01183429
3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Non-Myeloablative Therapy in Patients With High-Risk Neuroblastomatreatment2completed
NCT02743429
Phase II Study of Monoclonal Antibody ch14.18/CHO Continuous Infusion in Patients With Primary Refractory or Relapsed Neuroblastomatreatment2unknown_status
NCT04239092
9-ING-41 in Pediatric Patients With Refractory Malignancies.treatment1recruiting
NCT02558244
Impact of Image-defined Risk Factors on the Outcome of Patients With Neuroblastoma: A Retrospective StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00730444
Expanded Access Protocol for [123I]mIBG for Patients With Known or Suspected NeuroblastomaNot AvailableNot Availableapproved_for_marketing
NCT01077440
Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availableterminated
NCT04239040
GVAX Plus Checkpoint Blockade in Neuroblastomatreatment1active_not_recruiting
NCT00492167
Beta-Glucan and Monoclonal Antibody 3F8 in Treating Patients With Metastatic Neuroblastomatreatment1completed
NCT01802567
Molecular-Guided Therapy for Relapsed and Refractory Childhood CancerNo drug interventionstreatmentNot Availablecompleted
NCT00813501
Immunologic Diagnostic Blood Test in Predicting Side-Effects in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Other DiseasesNo drug interventionsNot AvailableNot Availableterminated
NCT01460901
Study of Donor Derived, Multi-virus-specific, Cytotoxic T-Lymphocytes for Relapsed/Refractory NeuroblastomaNo drug interventionstreatment1completed
NCT01358604
Biomarkers in Samples From Young Patients With NeuroblastomaNo drug interventionsNot AvailableNot Availablecompleted
NCT04017104
Dynamic Whole Body Positron Emission Tomography/Computed Tomography ImagingNo drug interventionsNot AvailableNot Availableunknown_status
NCT01662804
Humanized 3F8 Monoclonal Antibody (Hu3F8) When Combined With Interleukin-2 in Patients With High-Risk Neuroblastoma and GD2-positive Solid Tumorstreatment1completed
NCT00040872
Multiple Therapies in Treating Patients With Advanced Neuroblastomatreatment2completed
NCT01704872
ch14.18/CHO Bridging Studytreatment1completed
NCT00867568
TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastomatreatment1completed
NCT00588068
Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical OutcomeNo drug interventionsNot AvailableNot Availablerecruiting
NCT03050268
Familial Investigations of Childhood Cancer PredispositionNo drug interventionsNot AvailableNot Availablerecruiting
NCT00533169
ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastomatreatment1terminated
NCT01868269
Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)Opsoclonus Myoclonus Syndrome/Dancing Eye Syndrome (OMS/DES) in Children With and Without Neuroblastoma (NBpos and NBneg)treatment3active_not_recruiting
NCT00602446
Deferasirox in Treating Patients With Iron Overload After Undergoing a Donor Stem Cell Transplantsupportive_care2terminated
NCT03273712
Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)treatment2completed
NCT00126412
Meta-Iodobenzylguanidine (123I mIBG) Scintigraphy in Patients Being Evaluated for Phaeochromocytoma or Neuroblastomadiagnostic3completed
NCT00036712
Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow TransplantationNo drug interventionssupportive_care2unknown_status
NCT06182410
Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastomasupportive_care2withdrawn
NCT00025610
Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastomatreatment2completed
NCT00004110
Monoclonal Antibody Therapy Plus Etoposide in Treating Patients With Neuroblastomatreatment2completed
NCT05890781
Engineering Immune Organoids to Study Pediatric CancerNo drug interventionsotherNot Availablerecruiting
NCT03618381
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young AdultsNo drug interventionstreatment1recruiting
NCT05755295
Horse Therapy for Children, Adolescents and Young Adults in Remission From MedulloblastomaNo drug interventionssupportive_careNot Availablerecruiting
NCT01986595
A Pilot Study on ALK Gene Mutations in NeuroblastomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00365755
Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastomatreatment3completed
NCT00062855
Using Gene Modified Neuroblastoma Cells for the Treatment of Relapsed/Refractory NeuroblastomaNo drug interventionstreatment1completed
NCT05642455
SPEARHEAD-3 Pediatric StudyNo drug interventionstreatment1 / 2recruiting
NCT00923650
Informed Consent in Pediatric Cancer TrialsNo drug interventionsNot AvailableNot Availablecompleted
NCT00003750
Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumorstreatment1completed
NCT01156350
Haplo-identical Hematopoietic Stem Cell Transplantation Following Reduced-intensity Conditioning in Children With Neuroblastomatreatment2unknown_status
NCT00020150
Temozolomide and O6-benzylguanine in Treating Children With Solid Tumorstreatment1completed
NCT01019850
N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastomatreatment1completed
NCT05179850
Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT01204450
Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcomatreatment1terminated
NCT05245123
Psychosocial Situation of Children With Rare Solid Abdominal Tumors and Their FamiliesNo drug interventionsNot AvailableNot Availablecompleted
NCT00025623
Combination Chemotherapy Followed by Surgery in Treating Infants With Newly Diagnosed Neuroblastomatreatment2completed
NCT01130623
A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumorstreatment1withdrawn
NCT00003023
Monoclonal Antibody A1G4 Plus BCG in Treating Patients With Cancertreatment1completed
NCT00030108
Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapytreatment1completed
NCT01505608
Randomized Efficacy Study of TPI 287 to Treat Primary Refractory or Early Relapsed Neuroblastomatreatment1 / 2terminated
NCT00003743
Interleukin-2 in Treating Children With Stage IV Neuroblastoma Who Have Received Induction Therapy and Peripheral Stem Cell Transplantationtreatment2unknown_status
NCT02159443
Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A AntibodyNo drug interventionsNot AvailableNot Availablecompleted
NCT04301843
Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastomatreatment2recruiting
NCT02390843
Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumorstreatment1completed
NCT02630043
Trial of Tolcapone With Oxaliplatin for Neuroblastomatreatment1terminated
NCT01586260
Preventative Trial of DFMO in Patients With High Risk Neuroblastoma in Remissionprevention2active_not_recruiting
NCT02441088
Theranostics: 68GaDOTATOC and 90YDOTATOCtreatment2active_not_recruiting