Cardiotonic Agents
- Name
- Cardiotonic Agents
- Accession Number
- DBCAT000589
- Description
Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
- Drugs
Drug Drug Description Acetyldigitoxin Used for fast digitalization in congestive heart failure. Acetyldigoxin Not Annotated Acrihellin Acrihellin is a small molecule drug. Acrihellin has a monoisotopic molecular weight of 498.26 Da. Adrenomedullin Adrenomedullin is under investigation in clinical trial NCT06072118 (Adrenomedullin for CADASIL). Alifedrine Alifedrine is a small molecule drug. The usage of the INN stem '-drine' in the name indicates that Alifedrine is a sympathomimetic. Alifedrine has a monoisotopic molecular weight of 289.2... Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Amrinone A positive inotropic agent and phosphodiesterase inhibitor used in the management of treatment of congestive heart failure. Arbutamine Used to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in... Bimakalim Bimakalim is a small molecule drug. The usage of the INN stem '-kalim' in the name indicates that Bimakalim is a potassium channel activator, antihypertensive. Bimakalim has a monoisotopic molecular... Bufogenin Bufogenin is a small molecule drug. Bufogenin has a monoisotopic molecular weight of 384.23 Da. Canertinib Investigated for use/treatment in breast cancer and lung cancer. Carbamoylcholine A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. Colforsin Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;... Cymarin Not Annotated Denopamine Denopamine is a small molecule drug. Denopamine has a monoisotopic molecular weight of 317.16 Da. Deslanoside For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure. Dexrazoxane A cytoprotective drug used to prevent and improve cardiomyopathy associated with doxorubicin treatment for metastatic breast cancer. Digitoxin A cardiac glycoside used in the treatment and management of congestive cardiac insufficiency, arrhythmias and heart failure. Digoxin A cardiac glycoside used in the treatment of mild to moderate heart failure and for ventricular response rate control in chronic atrial fibrillation. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Dopamine A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. Enoximone A selective phosphodiesterase inhibitor indicated in the short term treatment of congestive heart failure. Etilefrine An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive. Higenamine Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects). Ibopamine A sympathomimetic, indicated in the induction of mydriasis and treatment of pos-surgical ocular hypotonia. Imazodan Imazodan is a small molecule drug. The usage of the INN stem '-dan' in the name indicates that Imazodan is a cardiac stimulant, pimobendan derivative. Imazodan has a monoisotopic molecular... Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. Levosimendan A calcium sensitizer indicated to treat acutely decompensated severe chronic heart failure. Lisinopril An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. Metildigoxin A digitalis glycoside indicated in the treatment of acute and chronic heart failure. Milrinone A PDE-III inhibitor with inotropic, lusitropic, and vasodilatory properties used for the short-term treatment of acute decompensated heart failure. Olprinone Not Annotated Ouabain For the treatment of atrial fibrillation and flutter and heart failure Oxyfedrine Not Annotated Peruvoside Not Annotated Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Phosphocreatine A cardioprotective agent indicated for use in cardiac surgery. Pimobendan Not Annotated Pirbuterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Piroximone Piroximone is a small molecule drug. Piroximone has a monoisotopic molecular weight of 217.09 Da. Plumbagin Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways. Prenalterol Not Annotated Proscillaridin Proscillaridin is a cardiac glycoside that is derived from plants of the genus Scilla and in Drimia maritima (Scilla maritima). Studies suggest the potential cytotoxic and anticancer property of proscillaridin,... Simendan Not Annotated Tedisamil Investigated for use/treatment in arrhythmia, atrial fibrillation, and angina. Vesnarinone Vesnarinone has been used in trials studying the treatment of HIV Infections and Sarcoma, Kaposi. Zatebradine Zatebradine is a small molecule drug. The usage of the INN stem '-bradine' in the name indicates that Zatebradine is a bradycardic agent. Zatebradine has a monoisotopic molecular weight of... - Drugs & Drug Targets