Malignant Neoplasm of Colon

Also known as: Cancer, Colon / Colonic Cancer / Colonic Cancers / Colon Cancer / Cancer of colon / Colon cancer NOS / Malignant neoplasm of colon, unspecified / Colonic cancer NOS

Drug	Drug Name	Drug Description
DB00115	Cyanocobalamin	A vitamin available in many formulations to correct vitamin B12 deficiency.
DB00544	Fluorouracil	A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
DB03419	Uracil	Not Available

Drug	Drug Name	Target	Type
DB00115	Cyanocobalamin	Methionine synthase reductase	target
DB00115	Cyanocobalamin	Methylmalonic aciduria type A protein, mitochondrial	target
DB00115	Cyanocobalamin	Methylmalonyl-CoA mutase, mitochondrial	target
DB00115	Cyanocobalamin	Methylmalonic aciduria and homocystinuria type C protein	target
DB00115	Cyanocobalamin	Methionine synthase	target
DB00115	Cyanocobalamin	Methylenetetrahydrofolate reductase	target
DB00115	Cyanocobalamin	Protein amnionless	transporter
DB00115	Cyanocobalamin	Transcobalamin-1	transporter
DB00115	Cyanocobalamin	Transcobalamin-2	transporter
DB00115	Cyanocobalamin	Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial	enzyme
DB00115	Cyanocobalamin	Gastric intrinsic factor	transporter
DB00115	Cyanocobalamin	Cubilin	transporter
DB00115	Cyanocobalamin	Bifunctional adenosylcobalamin biosynthesis protein CobU	enzyme
DB00115	Cyanocobalamin	Low-density lipoprotein receptor-related protein 2	transporter
DB00115	Cyanocobalamin	Multidrug resistance-associated protein 1	transporter
DB00115	Cyanocobalamin	Pancreatic proteases	enzyme
DB00544	Fluorouracil	Thymidylate synthase	target
DB00544	Fluorouracil	Cytochrome P450 1A2	enzyme
DB00544	Fluorouracil	Thymidine phosphorylase	enzyme
DB00544	Fluorouracil	Serum albumin	carrier
DB00544	Fluorouracil	Cytochrome P450 2C9	enzyme
DB00544	Fluorouracil	Dihydropyrimidine dehydrogenase [NADP(+)]	enzyme
DB00544	Fluorouracil	Uridine phosphorylase 1	enzyme
DB00544	Fluorouracil	Uridine phosphorylase 2	enzyme
DB00544	Fluorouracil	DNA	target
DB00544	Fluorouracil	RNA	target
DB00544	Fluorouracil	Cytochrome P450 2A6	enzyme
DB00544	Fluorouracil	Cytochrome P450 2C8	enzyme
DB00544	Fluorouracil	Methylenetetrahydrofolate reductase	enzyme
DB00544	Fluorouracil	Thymidylate synthase	enzyme
DB00544	Fluorouracil	Uridine 5'-monophosphate synthase	enzyme
DB00544	Fluorouracil	Amidophosphoribosyltransferase	enzyme
DB00544	Fluorouracil	Solute carrier family 22 member 7	transporter
DB00544	Fluorouracil	Equilibrative nucleoside transporter 1	transporter
DB00544	Fluorouracil	ATP-binding cassette sub-family G member 2	transporter
DB00544	Fluorouracil	Canalicular multispecific organic anion transporter 2	transporter
DB00544	Fluorouracil	Multidrug resistance-associated protein 4	transporter
DB00544	Fluorouracil	Multidrug resistance-associated protein 5	transporter
DB00544	Fluorouracil	Thyroxine-binding globulin	carrier
DB03419	Uracil	Dihydropyrimidine dehydrogenase [NADP(+)]	target
DB03419	Uracil	Uridine-cytidine kinase-like 1	target
DB03419	Uracil	Uracil-DNA glycosylase	target
DB03419	Uracil	Uracil-DNA glycosylase	target
DB03419	Uracil	Ribosomal small subunit pseudouridine synthase A	target
DB03419	Uracil	Uracil-DNA glycosylase	target
DB03419	Uracil	Pyrimidine-nucleoside phosphorylase	target

Drug	Drug Name	Phase	Status	Count
DB12116	Epigallocatechin gallate	0	Recruiting	1
DB14307	Green tea leaf	0	Recruiting	1
DB04868	Nilotinib	0	Withdrawn	1
DB12001	Abemaciclib	1	Completed	1
DB11105	Benzalkonium	1	Suspended	1
DB00112	Bevacizumab	1	Recruiting	1
DB11666	Buparlisib	1	Completed	1
DB05916	CT-011	1	Withdrawn	1
DB06724	Calcium carbonate	1	Active Not Recruiting	1
DB01101	Capecitabine	1	Completed	2
DB01101	Capecitabine	1	Unknown Status	1
DB00958	Carboplatin	1	Completed	2
DB00958	Carboplatin	1	Recruiting	1
DB00002	Cetuximab	1	Completed	1
DB00002	Cetuximab	1	Recruiting	1
DB00002	Cetuximab	1	Terminated	2
DB00515	Cisplatin	1	Completed	1
DB00515	Cisplatin	1	Recruiting	1
DB00531	Cyclophosphamide	1	Completed	1
DB00851	Dacarbazine	1	Active Not Recruiting	1
DB01248	Docetaxel	1	Active Not Recruiting	1
DB03516	Eniluracil	1	Terminated	1
DB12116	Epigallocatechin gallate	1	Recruiting	1
DB00530	Erlotinib	1	Active Not Recruiting	1
DB00322	Floxuridine	1	Active Not Recruiting	1
DB00544	Fluorouracil	1	Completed	2
DB00441	Gemcitabine	1	Completed	1
DB00441	Gemcitabine	1	Recruiting	1
DB14307	Green tea leaf	1	Recruiting	1
DB14865	Human interleukin-2	1	Completed	1
DB00619	Imatinib	1	Completed	1
DB00724	Imiquimod	1	Recruiting	1
DB06186	Ipilimumab	1	Recruiting	1
DB00762	Irinotecan	1	Active Not Recruiting	1
DB00762	Irinotecan	1	Completed	2
DB00762	Irinotecan	1	Recruiting	1
DB04845	Ixabepilone	1	Terminated	1
DB12167	LY-3023414	1	Completed	1
DB12050	LY-3039478	1	Completed	1
DB00480	Lenalidomide	1	Terminated	1
DB00650	Leucovorin	1	Completed	2
DB00650	Leucovorin	1	Recruiting	1
DB12583	Maltodextrin	1	Active Not Recruiting	1
DB00331	Metformin	1	Terminated	1
DB14375	Milk thistle	1	Recruiting	1
DB05575	Motesanib	1	Completed	1
DB14995	NP-G2-044	1	Completed	1
DB06803	Niclosamide	1	Terminated	1
DB09035	Nivolumab	1	Active Not Recruiting	1
DB09035	Nivolumab	1	Recruiting	1
DB00043	Omalizumab	1	Completed	1
DB00526	Oxaliplatin	1	Active Not Recruiting	1
DB00526	Oxaliplatin	1	Completed	1
DB01229	Paclitaxel	1	Completed	1
DB01229	Paclitaxel	1	Recruiting	1
DB01269	Panitumumab	1	Completed	1
DB03010	Patupilone	1	Completed	1
DB06589	Pazopanib	1	Terminated	1
DB09037	Pembrolizumab	1	Recruiting	1
DB06641	Perifosine	1	Completed	1
DB05578	Ramucirumab	1	Recruiting	1
DB15752	Recombinant Super-Compound Interferon	1	Completed	1
DB08896	Regorafenib	1	Active Not Recruiting	1
DB02709	Resveratrol	1	Completed	1
DB11689	Selumetinib	1	Active Not Recruiting	1
DB11689	Selumetinib	1	Completed	1
DB08937	TAS-102	1	Recruiting	1
DB12550	Taladegib	1	Completed	1
DB06287	Temsirolimus	1	Active Not Recruiting	1
DB09343	Tipiracil	1	Recruiting	1
DB00432	Trifluridine	1	Recruiting	1
DB07232	Veliparib	1	Completed	2
DB04986	ZYC300	1	Completed	1
DB00041	Aldesleukin	1 / 2	Active Not Recruiting	2
DB00041	Aldesleukin	1 / 2	Recruiting	1
DB00855	Aminolevulinic acid	1 / 2	Withdrawn	1
DB00112	Bevacizumab	1 / 2	Completed	2
DB12744	CGI-1842	1 / 2	Terminated	1
DB01101	Capecitabine	1 / 2	Completed	1
DB01101	Capecitabine	1 / 2	Recruiting	1
DB00482	Celecoxib	1 / 2	Unknown Status	1
DB11646	Conatumumab	1 / 2	Completed	2
DB12483	Copanlisib	1 / 2	Recruiting	1
DB11672	Curcumin	1 / 2	Completed	1
DB00531	Cyclophosphamide	1 / 2	Active Not Recruiting	2
DB00531	Cyclophosphamide	1 / 2	Recruiting	1
DB15198	Dextromethadone	1 / 2	Completed	1
DB11714	Durvalumab	1 / 2	Recruiting	1
DB12505	E-7820	1 / 2	Completed	1
DB01590	Everolimus	1 / 2	Terminated	1
DB01073	Fludarabine	1 / 2	Active Not Recruiting	2
DB01073	Fludarabine	1 / 2	Recruiting	1
DB00544	Fluorouracil	1 / 2	Completed	2
DB12205	Ganitumab	1 / 2	Completed	1
DB00441	Gemcitabine	1 / 2	Recruiting	1
DB01645	Genistein	1 / 2	Completed	1
DB06261	Hexaminolevulinate	1 / 2	Terminated	1
DB01611	Hydroxychloroquine	1 / 2	Completed	1
DB09053	Ibrutinib	1 / 2	Active Not Recruiting	1
DB06186	Ipilimumab	1 / 2	Recruiting	1
DB00762	Irinotecan	1 / 2	Completed	1
DB05097	Labetuzumab	1 / 2	Completed	2
DB05097	Labetuzumab	1 / 2	Withdrawn	1
DB12331	Labetuzumab govitecan	1 / 2	Withdrawn	1
DB00650	Leucovorin	1 / 2	Completed	2
DB00295	Morphine	1 / 2	Completed	1
DB15721	Natural Killer Cell	1 / 2	Recruiting	1
DB09035	Nivolumab	1 / 2	Recruiting	1
DB00526	Oxaliplatin	1 / 2	Completed	1
DB01269	Panitumumab	1 / 2	Completed	2
DB03010	Patupilone	1 / 2	Unknown Status	1
DB09037	Pembrolizumab	1 / 2	Active Not Recruiting	1
DB09037	Pembrolizumab	1 / 2	Recruiting	1
DB11972	Rilotumumab	1 / 2	Completed	1
DB15685	Selpercatinib	1 / 2	Recruiting	1
DB15232	Telaglenastat	1 / 2	Recruiting	1
DB06552	rNAPc2	1 / 2	Suspended	1
DB05308	ANX-510	2	Completed	2
DB00945	Acetylsalicylic acid	2	Completed	1
DB11702	Antineoplaston A10	2	Terminated	1
DB00126	Ascorbic acid	2	Completed	2
DB01076	Atorvastatin	2	Completed	1
DB00112	Bevacizumab	2	Active Not Recruiting	2
DB00112	Bevacizumab	2	Completed	3
DB00112	Bevacizumab	2	Terminated	2
DB14776	Camrelizumab	2	Not Yet Recruiting	1
DB01101	Capecitabine	2	Completed	4
DB01101	Capecitabine	2	Recruiting	2
DB01101	Capecitabine	2	Terminated	2
DB00002	Cetuximab	2	Completed	2
DB00002	Cetuximab	2	Recruiting	1
DB00002	Cetuximab	2	Terminated	1
DB00002	Cetuximab	2	Withdrawn	1
DB12250	Cixutumumab	2	Terminated	1
DB06643	Denosumab	2	Completed	1
DB11714	Durvalumab	2	Active Not Recruiting	1
DB00544	Fluorouracil	2	Active Not Recruiting	1
DB00544	Fluorouracil	2	Completed	7
DB00544	Fluorouracil	2	Recruiting	1
DB00544	Fluorouracil	2	Terminated	1
DB00158	Folic acid	2	Completed	1
DB13034	Foxy-5	2	Recruiting	1
DB05698	GI-4000	2	Terminated	1
DB12047	Ganetespib	2	Completed	1
DB00441	Gemcitabine	2	Completed	1
DB09257	Gimeracil	2	Terminated	1
DB10989	Hepatitis A Vaccine	2	Terminated	1
DB11627	Hepatitis B Vaccine (Recombinant)	2	Terminated	1
DB08887	Icosapent ethyl	2	Recruiting	1
DB14824	Icrucumab	2	Completed	1
DB11997	Interleukin-7	2	Terminated	1
DB00638	Inulin	2	Completed	1
DB06186	Ipilimumab	2	Active Not Recruiting	1
DB00762	Irinotecan	2	Active Not Recruiting	1
DB00762	Irinotecan	2	Completed	5
DB00762	Irinotecan	2	Recruiting	1
DB00762	Irinotecan	2	Terminated	3
DB00762	Irinotecan	2	Withdrawn	1
DB00650	Leucovorin	2	Active Not Recruiting	1
DB00650	Leucovorin	2	Completed	8
DB00650	Leucovorin	2	Recruiting	1
DB00650	Leucovorin	2	Terminated	1
DB00281	Lidocaine	2	Completed	1
DB06796	Mangafodipir	2	Completed	1
DB00331	Metformin	2	Completed	1
DB00331	Metformin	2	Recruiting	1
DB09035	Nivolumab	2	Active Not Recruiting	1
DB11133	Omega-3 fatty acids	2	Recruiting	1
DB03209	Oteracil	2	Terminated	1
DB00526	Oxaliplatin	2	Completed	5
DB00526	Oxaliplatin	2	Terminated	3
DB09073	Palbociclib	2	Recruiting	1
DB01269	Panitumumab	2	Active Not Recruiting	1
DB01269	Panitumumab	2	Completed	5
DB00019	Pegfilgrastim	2	Completed	1
DB09037	Pembrolizumab	2	Not Yet Recruiting	1
DB06641	Perifosine	2	Completed	1
DB09287	Polyethylene glycol	2	Completed	2
DB00761	Potassium chloride	2	Completed	2
DB05578	Ramucirumab	2	Completed	1
DB08896	Regorafenib	2	Terminated	1
DB05386	Regramostim	2	Unknown Status	1
DB14765	Rivoceranib	2	Not Yet Recruiting	1
DB14482	Sodium ascorbate	2	Completed	2
DB09153	Sodium chloride	2	Completed	2
DB09472	Sodium sulfate	2	Completed	2
DB00605	Sulindac	2	Completed	1
DB09256	Tegafur	2	Terminated	1
DB09256	Tegafur	2	Unknown Status	1
DB01041	Thalidomide	2	Unknown Status	1
DB15373	Tilmanocept	2	Completed	1
DB01030	Topotecan	2	Completed	1
DB08911	Trametinib	2	Active Not Recruiting	1
DB12056	Trebananib	2	Completed	1
DB00361	Vinorelbine	2	Unknown Status	1
DB13076	Yttrium Y-90	2	Withdrawn	1
DB01101	Capecitabine	2 / 3	Not Yet Recruiting	1
DB00544	Fluorouracil	2 / 3	Not Yet Recruiting	1
DB00762	Irinotecan	2 / 3	Not Yet Recruiting	1
DB00650	Leucovorin	2 / 3	Not Yet Recruiting	1
DB00039	Palifermin	2 / 3	Completed	1
DB00302	Tranexamic acid	2 / 3	Unknown Status	1
DB05308	ANX-510	3	Unknown Status	1
DB00945	Acetylsalicylic acid	3	Recruiting	3
DB00112	Bevacizumab	3	Completed	1
DB00112	Bevacizumab	3	Recruiting	1
DB00112	Bevacizumab	3	Unknown Status	1
DB01101	Capecitabine	3	Not Yet Recruiting	1
DB01101	Capecitabine	3	Recruiting	3
DB00482	Celecoxib	3	Completed	1
DB00544	Fluorouracil	3	Active Not Recruiting	1
DB00544	Fluorouracil	3	Recruiting	1
DB00544	Fluorouracil	3	Unknown Status	1
DB09106	Hydroxyethyl Starch	3	Completed	1
DB08887	Icosapent ethyl	3	Recruiting	1
DB00650	Leucovorin	3	Active Not Recruiting	1
DB00650	Leucovorin	3	Completed	1
DB00650	Leucovorin	3	Recruiting	1
DB00650	Leucovorin	3	Unknown Status	1
DB11596	Levoleucovorin	3	Completed	1
DB00825	Levomenthol	3	Terminated	1
DB00281	Lidocaine	3	Not Yet Recruiting	1
DB01017	Minocycline	3	Recruiting	1
DB13026	Ornidazole	3	Recruiting	1
DB00526	Oxaliplatin	3	Active Not Recruiting	1
DB00526	Oxaliplatin	3	Completed	1
DB00526	Oxaliplatin	3	Not Yet Recruiting	1
DB00526	Oxaliplatin	3	Recruiting	3
DB00019	Pegfilgrastim	3	Completed	1
DB11198	Peppermint oil	3	Terminated	1
DB09287	Polyethylene glycol	3	Completed	1
DB00761	Potassium chloride	3	Completed	1
DB00818	Propofol	3	Not Yet Recruiting	1
DB11365	Sennosides	3	Recruiting	1
DB01236	Sevoflurane	3	Not Yet Recruiting	1
DB01390	Sodium bicarbonate	3	Completed	1
DB09153	Sodium chloride	3	Completed	1
DB09472	Sodium sulfate	3	Completed	1
DB00316	Acetaminophen	4	Unknown Status	1
DB00112	Bevacizumab	4	Active Not Recruiting	1
DB00297	Bupivacaine	4	Completed	1
DB00297	Bupivacaine	4	Unknown Status	1
DB00813	Fentanyl	4	Completed	1
DB00813	Fentanyl	4	Unknown Status	1
DB13961	Fish oil	4	Completed	1
DB00544	Fluorouracil	4	Active Not Recruiting	1
DB00544	Fluorouracil	4	Not Yet Recruiting	1
DB00996	Gabapentin	4	Unknown Status	1
DB00040	Glucagon	4	Completed	1
DB00956	Hydrocodone	4	Unknown Status	1
DB00327	Hydromorphone	4	Unknown Status	1
DB00762	Irinotecan	4	Active Not Recruiting	1
DB01221	Ketamine	4	Unknown Status	1
DB00465	Ketorolac	4	Unknown Status	1
DB00650	Leucovorin	4	Active Not Recruiting	1
DB00281	Lidocaine	4	Unknown Status	1
DB01377	Magnesium oxide	4	Completed	1
DB00333	Methadone	4	Unknown Status	1
DB00683	Midazolam	4	Completed	1
DB00295	Morphine	4	Completed	1
DB00295	Morphine	4	Unknown Status	1
DB11133	Omega-3 fatty acids	4	Completed	1
DB01173	Orphenadrine	4	Unknown Status	1
DB00526	Oxaliplatin	4	Active Not Recruiting	1
DB01269	Panitumumab	4	Active Not Recruiting	1
DB12492	Piritramide	4	Completed	1
DB09287	Polyethylene glycol	4	Completed	1
DB00761	Potassium chloride	4	Completed	1
DB00818	Propofol	4	Completed	1
DB00296	Ropivacaine	4	Not Yet Recruiting	1
DB01390	Sodium bicarbonate	4	Completed	1
DB09153	Sodium chloride	4	Completed	1
DB09472	Sodium sulfate	4	Completed	1
DB11251	Tocopherol	4	Completed	1
DB00193	Tramadol	4	Unknown Status	1
DB00945	Acetylsalicylic acid	Not Available	Unknown Status	1
DB00126	Ascorbic acid	Not Available	Completed	1
DB00112	Bevacizumab	Not Available	Completed	1
DB00112	Bevacizumab	Not Available	Not Yet Recruiting	1
DB00112	Bevacizumab	Not Available	Terminated	1
DB09020	Bisacodyl	Not Available	Completed	1
DB09020	Bisacodyl	Not Available	Unknown Status	1
DB00482	Celecoxib	Not Available	Terminated	1
DB09130	Copper	Not Available	Active Not Recruiting	1
DB01262	Decitabine	Not Available	Terminated	1
DB00633	Dexmedetomidine	Not Available	Completed	1
DB00813	Fentanyl	Not Available	Unknown Status	1
DB08917	Ferric carboxymaltose	Not Available	Recruiting	1
DB00544	Fluorouracil	Not Available	Active Not Recruiting	1
DB01050	Ibuprofen	Not Available	Unknown Status	1
DB15763	Iron polymaltose	Not Available	Recruiting	1
DB00650	Leucovorin	Not Available	Active Not Recruiting	2
DB00825	Levomenthol	Not Available	Active Not Recruiting	1
DB00281	Lidocaine	Not Available	Completed	1
DB01233	Metoclopramide	Not Available	Unknown Status	1
DB00683	Midazolam	Not Available	Unknown Status	1
DB09413	Monopotassium phosphate	Not Available	Unknown Status	1
DB00295	Morphine	Not Available	Completed	1
DB00526	Oxaliplatin	Not Available	Active Not Recruiting	1
DB00526	Oxaliplatin	Not Available	Completed	2
DB09287	Polyethylene glycol	Not Available	Completed	1
DB09287	Polyethylene glycol	Not Available	Unknown Status	1
DB00761	Potassium chloride	Not Available	Completed	1
DB00818	Propofol	Not Available	Unknown Status	2
DB09290	Ramosetron	Not Available	Completed	1
DB15685	Selpercatinib	Not Available	Temporarily Not Available	1
DB01236	Sevoflurane	Not Available	Unknown Status	1
DB14482	Sodium ascorbate	Not Available	Completed	1
DB09153	Sodium chloride	Not Available	Completed	2
DB14502	Sodium phosphate, dibasic	Not Available	Unknown Status	1
DB09468	Sodium phosphate, monobasic	Not Available	Unknown Status	1
DB09472	Sodium sulfate	Not Available	Completed	1