Joint Pain

Also known as: Arthralgias / Joint pains / Arthralgia/joint pain / Pain, Joint / Pain in joint / Arthralgia / (Pain in joint) or (coxalgia) / Joint: [pain - arthralgia] or [ache] / Joint ache / Arthritic-like pain / Painful joints / Pain in joint, site unspecified / Discomfort in joints / Joint pain (finding) / Arthralgia NOS / Arthralgia NOS (finding) / Pain joint / Aching joints

DrugDrug NameDrug Description
DB11344(+)-mentholNot Annotated
DB11345(S)-camphorIndicated for the temporary symptomatic relief of minor aches and pains of muscles and joints in topical analgesics.
DB00181BaclofenA GABA-ergic agonist used to manage severe spasticity of cerebral or spinal origin in adult and pediatric patients.
DB11288BorneolNot Annotated
DB01744CamphorA compound used topically to help relieve pain and also as a topical antiseptic. May also be used in vaporizers to help suppress coughing. This medication should not be swallowed.
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB01364EphedrineAn alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion.
DB16159EsflurbiprofenAn NSAID formulated as a topical product for osteoarthritis associated joint pain and inflammation.
DB01296GlucosamineA common ingredient in nutritional supplements used for the relief of joint pain.
DB11323Glycol salicylateA salicylate used to treat mild to moderate muscle pain.
DB00328IndomethacinA nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
DB00825LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB11201Menthyl salicylateFor the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis .
DB09543Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
DB15785MyrtecaineA local anesthetic used in topical products.
DB11324NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
DB00140RiboflavinA vitamin used to correct vitamin B2 deficiency.
DB14156Synthetic camphorNot Annotated
DB02513ThymolAn essential oil found in various over-the-counter antibacterial and antifungal products.
DB11120TurpentineA medication used to treat minor aches and pains of muscles and joints.
DrugDrug NameTargetType
DB11345(S)-camphorTransient receptor potential cation channel subfamily V member 1target
DB11345(S)-camphorTransient receptor potential cation channel subfamily V member 3target
DB11345(S)-camphorTransient receptor potential cation channel subfamily A member 1target
DB11345(S)-camphorTransient receptor potential cation channel subfamily M member 8target
DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 1target
DB00181BaclofenGamma-aminobutyric acid type B receptor subunit 2target
DB01744CamphorCamphor 5-monooxygenasetarget
DB01744CamphorTransient receptor potential cation channel subfamily V member 1target
DB01744CamphorTransient receptor potential cation channel subfamily V member 3target
DB01744CamphorTransient receptor potential cation channel subfamily A member 1target
DB01744CamphorTransient receptor potential cation channel subfamily M member 8target
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB00586DiclofenacP-glycoprotein 1transporter
DB01364EphedrineAlpha-1A adrenergic receptortarget
DB01364EphedrineSodium-dependent noradrenaline transportertarget
DB01364EphedrineCholinesteraseenzyme
DB01364EphedrineSerum albumincarrier
DB01364EphedrineBeta-1 adrenergic receptortarget
DB01364EphedrineBeta-2 adrenergic receptortarget
DB01364EphedrineSynaptic vesicular amine transportertransporter
DB01364EphedrineAcetylcholinesteraseenzyme
DB01296GlucosamineInterferon gammatarget
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 2transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 1transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 4transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 3transporter
DB01296GlucosamineTranscription factor p65target
DB11323Glycol salicylateProstaglandin G/H synthase 1target
DB11323Glycol salicylateProstaglandin G/H synthase 2target
DB00328IndomethacinProstaglandin G/H synthase 1target
DB00328IndomethacinProstaglandin G/H synthase 2target
DB00328IndomethacinCytochrome P450 2C19enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-9enzyme
DB00328IndomethacinPhospholipase A2, membrane associatedtarget
DB00328IndomethacinProstaglandin reductase 2target
DB00328IndomethacinLactoylglutathione lyasetarget
DB00328IndomethacinProstaglandin D2 receptor 2target
DB00328IndomethacinPeroxisome proliferator-activated receptor gammatarget
DB00328IndomethacinSerum albumincarrier
DB00328IndomethacinCanalicular multispecific organic anion transporter 2transporter
DB00328IndomethacinMultidrug resistance-associated protein 4transporter
DB00328IndomethacinMultidrug resistance-associated protein 6transporter
DB00328IndomethacinP-glycoprotein 1transporter
DB00328IndomethacinMultidrug resistance-associated protein 1transporter
DB00328IndomethacinSolute carrier organic anion transporter family member 1A2transporter
DB00328IndomethacinSolute carrier family 22 member 6transporter
DB00328IndomethacinSolute carrier family 22 member 8transporter
DB00328IndomethacinCanalicular multispecific organic anion transporter 1transporter
DB00328IndomethacinATP-binding cassette sub-family C member 11transporter
DB00328IndomethacinSolute carrier family 22 member 11transporter
DB00328IndomethacinSodium/bile acid cotransportertransporter
DB00328IndomethacinSolute carrier family 22 member 7transporter
DB00328IndomethacinCytochrome P450 2C9enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 1-1enzyme
DB00328IndomethacinLiver carboxylesterase 1enzyme
DB00328IndomethacinUDP-glucuronosyltransferase 2B7enzyme
DB00328IndomethacinPeroxisome proliferator-activated receptor alphatarget
DB00328IndomethacinAldo-keto reductase family 1 member C3target
DB00328IndomethacinSolute carrier organic anion transporter family member 1B1transporter
DB00328IndomethacinBile salt export pumptransporter
DB00328IndomethacinInterferon-induced, double-stranded RNA-activated protein kinasetarget
DB00825LevomentholTransient receptor potential cation channel subfamily A member 1target
DB00825LevomentholTransient receptor potential cation channel subfamily M member 8target
DB00825LevomentholTransient receptor potential cation channel subfamily V member 3target
DB00825LevomentholKappa-type opioid receptortarget
DB00825LevomentholVoltage-dependent L-type calcium channeltarget
DB00825LevomentholCytochrome P450 3A4enzyme
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB11201Menthyl salicylateProstaglandin G/H synthase 1target
DB11201Menthyl salicylateProstaglandin G/H synthase 2target
DB11324NonivamideTransient receptor potential cation channel subfamily V member 1target
DB00140RiboflavinFlavin reductase (NADPH)target
DB00140RiboflavinRiboflavin kinasetarget
DB00140RiboflavinRiboflavin synthasetarget
DB00140RiboflavinAmine oxidase [flavin-containing] Aenzyme
DB00140RiboflavinMethylenetetrahydrofolate reductaseenzyme
DB00140RiboflavinSolute carrier family 22 member 6transporter
DB11120TurpentineMitogen-activated protein kinase 1target
DrugDrug NamePhaseStatusCount
DB14007Pentetic acid1 / 2Terminated1
DB01593Zinc1 / 2Terminated1
DB01373Calcium2Completed1
DB11126Calcium gluconate2Completed1
DB09061Cannabidiol2Recruiting1
DB00169Cholecalciferol2Completed1
DB09301Chondroitin sulfate2Completed1
DB00586Diclofenac2Terminated1
DB00783Estradiol2Recruiting1
DB12102Fulranumab2Terminated2
DB01296Glucosamine2Completed1
DB04703Hesperidin2Completed1
DB08818Hyaluronic acid2Withdrawn1
DB01611Hydroxychloroquine2Recruiting1
DB01006Letrozole2Completed1
DB01283Lumiracoxib2Terminated1
DB00497Oxycodone2Terminated1
DB00635Prednisone2Recruiting1
DB00624Testosterone2Unknown Status1
DB00996Gabapentin2 / 3Unknown Status1
DB01281Abatacept3Completed1
DB00316Acetaminophen3Enrolling by Invitation1
DB00201Caffeine3Enrolling by Invitation1
DB01009Ketoprofen3Completed1
DB00904Ondansetron3Enrolling by Invitation1
DB00497Oxycodone3Completed1
DB00497Oxycodone3Enrolling by Invitation1
DB00296Ropivacaine3Enrolling by Invitation1
DB06204Tapentadol3Completed4
DB00624Testosterone3Completed1
DB00316Acetaminophen4Completed1
DB00921Buprenorphine4Completed2
DB09061Cannabidiol4Recruiting1
DB00959Methylprednisolone4Completed1
DB01217AnastrozoleNot AvailableCompleted4
DB01217AnastrozoleNot AvailableUnknown Status1
DB00898EthanolNot AvailableCompleted1
DB00990ExemestaneNot AvailableCompleted2
DB08818Hyaluronic acidNot AvailableWithdrawn1
DB01006LetrozoleNot AvailableCompleted3
DB01006LetrozoleNot AvailableUnknown Status1
DB11057Mineral oilNot AvailableEnrolling by Invitation1
DB00675TamoxifenNot AvailableCompleted1