Pravastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke. |
Lovastatin | An HMG-CoA reductase inhibitor used to lower LDL cholesterol and reduce the risk of cardiovascular disease and associated conditions, including myocardial infarction and stroke. |
Colestipol | A bile acid sequestrant used as an adjunct to diet and exercise to reduce LDL-C cholesterol levels in patients with primary hypercholesterolemia. |
Cerivastatin | A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. |
Dextrothyroxine | A thyroid hormone used to treat hyperlipidemia. |
Clofibrate | A fibric acid derivative used to treat hypertriglyceridemia and high cholesterol. |
Simvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke. |
Colesevelam | A bile acid sequestrant used to lower LDL-C in adults with hyperlipidemia and pediatric patients with heterozygous familial hypercholesterolemia, and to improve glycemic control in type 2 diabetes. |
Ezetimibe | A cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo-B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia. |
Fenofibrate | A peroxisome proliferator receptor alpha activator used to lower LDL-C, total-C, triglycerides, and Apo B, while increasing HDL-C in hypercholesterolemia, dyslipidemia, and hypertriglyceridemia. |
Atorvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
Fluvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
Rosuvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
Gemfibrozil | A lipid regulator that is used in the reduction of serum triglyceride levels in high-risk patients with hyperlipidemia. |
Bezafibrate | A lipid-lowering fibrate used in the management of primary and secondary hyperlipidaemia, when there is a lack of clinical improvement following lifestyle modifications or correction of the underlying disorder. |
Cholestyramine | A bile acid sequestrant used as an adjunct in the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia, and for the relief of pruritus associated with partial biliary obstruction. |
Probucol | Used to lower LDL and HDL cholesterol. |
Mipomersen | An oligonucleotide drug used for the treatment of homozygous familial hypercholesterolemia. |
Lomitapide | A microsomal triglyceride transfer protein inhibitor used to lower cholesterol associated with homozygous familial hypercholesterolemia (HoFH), reducing risk of cardiovascular events such as myocardial infarction and stroke. |
Pitavastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
Etofibrate | Etofibrate is a fibrate produced by the combination of clofibrate ester linked to niacin. These components separate in the body slowly allowing for pharmacokinetics similar to controlled-release formulations. |
Acipimox | Used in the treatment of hyperlipidemias (abnormally elevated levels of any or all lipids and/or lipoproteins in the blood). |
Ciprofibrate | Not Annotated |
Evolocumab | A PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor antibody used as an adjunct to LDL cholesterol reducing therapies, aiding in the prevention of cardiovascular events and cardiovascular revascularization procedures. |
Tiadenol | Not Annotated |
Nicofuranose | Not Annotated |
Simfibrate | Not Annotated |
Niceritrol | Not Annotated |
Ronifibrate | Not Annotated |
Alipogene tiparvovec | Not Annotated |
Aluminium nicotinate | Not Annotated |
Aluminium clofibrate | Not Annotated |
Clofibride | Not Annotated |
Fenofibric acid | A fibrate used to treat severe hypertriglyceridemia, primary hypercholesterolemia, or mixed dyslipidemia. |
Ramipril | An ACE inhibitor used for the management of hypertension and the reduction of cardiovascular mortality following myocardial infarction in hemodynamically stable patients with clinical signs of congestive heart failure. |
Niacin | A B vitamin used to treat hypertriglyceridemia and pellagra. |
Lisinopril | An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. |
Perindopril | An ACE inhibitor prodrug used to treat hypertension, mild to moderate congestive heart failure, and to reduce cardiovascular risk in patients with hypertension or post-myocardial infarction. |
Nicotinyl alcohol | A direct-acting peripheral vasodilator that causes flushing and may decrease blood pressure. It is used in vasospasm and threatened gangrene. [PubChem] |
Meglutol | An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as... |
Indapamide | A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. |
Alirocumab | A PCSK9 inhibitor used as an adjunct to manage heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in patients who require additional lowering of LDL-cholesterol (LDL-C). |
Fimasartan | Used for the treatment of hypertension and heart failure . |
Bempedoic acid | A drug used in conjunction with lifestyle modification and/or other agents for the treatment of refractory hypercholesterolemia. |
Inclisiran | A PCSK9-targeted short interfering RNA that lowers plasma LDL-cholesterol levels. |