Maintenance therapy

DrugDrug NameDrug Description
DB00058Alpha-1-proteinase inhibitorA purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
DB06216AsenapineAn atypical antipsychotic used to treat patients with bipolar I disorder and patients with schizophrenia.
DB11945AvelumabAn anti-PD-L1 monoclonal antibody used to treat metastatic merkel cell carcinoma, metastatic urothelial carcinoma, or renal cell carcinoma.
DB01222BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
DB06775Carglumic acidAn analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.
DB12159DupilumabA monoclonal antibody used to treat moderate to severe atopic dermatitis, asthma, and nasal polyps accompanied by chronic rhinosinusitis in adolescents and adults.
DB00472FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
DB00983FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
DB00028Human immunoglobulin GA purified form of human immunoglobulin G and other proteins used to treat immunodeficiency and a wide variety of autoimmune disorders.
DB00333MethadoneAn opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction.
DB11793NiraparibA poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
DB09074OlaparibA poly (ADP-ribose) polymerase (PARP) inhibitor used to treat ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
DB12332RucaparibA poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
DB00421SpironolactoneAn aldosterone receptor antagonist used to treat edema, hypertension, heart failure, and aldosteronism.
DrugDrug NameTargetType
DB00058Alpha-1-proteinase inhibitorNeutrophil elastasetarget
DB06216Asenapine5-hydroxytryptamine receptor 1Atarget
DB06216Asenapine5-hydroxytryptamine receptor 1Btarget
DB06216Asenapine5-hydroxytryptamine receptor 2Atarget
DB06216Asenapine5-hydroxytryptamine receptor 2Btarget
DB06216Asenapine5-hydroxytryptamine receptor 2Ctarget
DB06216Asenapine5-hydroxytryptamine receptor 6target
DB06216Asenapine5-hydroxytryptamine receptor 7target
DB06216AsenapineAlpha-2A adrenergic receptortarget
DB06216AsenapineAlpha-2B adrenergic receptortarget
DB06216AsenapineAlpha-2C adrenergic receptortarget
DB06216AsenapineAlpha-1A adrenergic receptortarget
DB06216AsenapineDopamine D1 receptortarget
DB06216AsenapineDopamine D2 receptortarget
DB06216AsenapineDopamine D3 receptortarget
DB06216AsenapineDopamine D4 receptortarget
DB06216AsenapineHistamine H1 receptortarget
DB06216AsenapineHistamine H2 receptortarget
DB06216AsenapineCytochrome P450 1A2enzyme
DB06216AsenapineCytochrome P450 2D6enzyme
DB06216Asenapine5-hydroxytryptamine receptor 5Atarget
DB06216AsenapineUDP-glucuronosyltransferase 1-4enzyme
DB06216AsenapineCytochrome P450 3A4enzyme
DB06216AsenapineBeta-1 adrenergic receptortarget
DB06216AsenapineBeta-2 adrenergic receptortarget
DB06216AsenapineSerum albumincarrier
DB06216Asenapinealpha1-acid glycoproteincarrier
DB11945AvelumabProgrammed cell death 1 ligand 1target
DB01222BudesonideGlucocorticoid receptortarget
DB01222BudesonideCytochrome P450 3A4enzyme
DB01222BudesonideCytochrome P450 3A5enzyme
DB01222BudesonideBile salt export pumptransporter
DB01222BudesonideP-glycoprotein 1transporter
DB01222BudesonideAnnexin A1target
DB01222BudesonideCytochrome P450 3A Subfamilyenzyme
DB01222BudesonideCytochrome P450 2A6enzyme
DB01222BudesonideCytochrome P450 1B1enzyme
DB01222BudesonideCytochrome P450 2B6enzyme
DB01222BudesonideCytochrome P450 2C8enzyme
DB01222BudesonideCytochrome P450 2C9enzyme
DB01222BudesonideCytochrome P450 2C19enzyme
DB01222BudesonideCorticosteroid-binding globulincarrier
DB01222BudesonideSolute carrier organic anion transporter family member 1A2transporter
DB01222BudesonideSolute carrier family 22 member 8transporter
DB01222BudesonideSerum albumincarrier
DB06775Carglumic acidCarbamoyl-phosphate synthase [ammonia], mitochondrialtarget
DB12159DupilumabInterleukin-4 receptor subunit alphatarget
DB12159DupilumabInterleukin-13target
DB12159DupilumabInterleukin-4target
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineP-glycoprotein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00983FormoterolBeta-2 adrenergic receptortarget
DB00983FormoterolBeta-1 adrenergic receptortarget
DB00983FormoterolBeta-3 adrenergic receptortarget
DB00983FormoterolCytochrome P450 2D6enzyme
DB00983FormoterolCytochrome P450 2C19enzyme
DB00983FormoterolCytochrome P450 2C9enzyme
DB00983FormoterolCytochrome P450 2A6enzyme
DB00983FormoterolUDP-glucuronosyltransferase 1A1enzyme
DB00983FormoterolUDP-glucuronosyltransferase 1-8enzyme
DB00983FormoterolUDP-glucuronosyltransferase 1-9enzyme
DB00983FormoterolUDP-glucuronosyltransferase 2B7enzyme
DB00983FormoterolUDP-glucuronosyltransferase 2B15enzyme
DB00983FormoterolSolute carrier family 22 member 1transporter
DB00983FormoterolSolute carrier family 22 member 4transporter
DB00983FormoterolSolute carrier family 22 member 5transporter
DB00983FormoterolSolute carrier family 22 member 3transporter
DB00983FormoterolSerum albumincarrier
DB00028Human immunoglobulin GLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00028Human immunoglobulin GLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00028Human immunoglobulin GHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00028Human immunoglobulin GLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00028Human immunoglobulin GLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00028Human immunoglobulin GLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00028Human immunoglobulin GHigh affinity immunoglobulin gamma Fc receptor IBtarget
DB00028Human immunoglobulin GComplement C3target
DB00028Human immunoglobulin GComplement C4-Atarget
DB00028Human immunoglobulin GComplement C4-Btarget
DB00028Human immunoglobulin GComplement C5target
DB00333MethadoneNMDA receptortarget
DB00333MethadoneMu-type opioid receptortarget
DB00333MethadoneCytochrome P450 2B6enzyme
DB00333MethadoneCytochrome P450 3A4enzyme
DB00333MethadoneCytochrome P450 2C19enzyme
DB00333MethadoneDelta-type opioid receptortarget
DB00333MethadoneCytochrome P450 3A7enzyme
DB00333MethadoneCytochrome P450 2D6enzyme
DB00333MethadoneP-glycoprotein 1transporter
DB00333MethadoneCytochrome P450 2C8enzyme
DB00333MethadoneCytochrome P450 19A1enzyme
DB00333MethadoneCytochrome P450 1A2enzyme
DB00333MethadoneCytochrome P450 2C18enzyme
DB00333MethadoneCytochrome P450 2C9enzyme
DB00333Methadone5-hydroxytryptamine receptor 3Atarget
DB00333MethadoneAlpha-1-acid glycoprotein 1carrier
DB00333MethadoneSerum albumincarrier
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-7target
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-3target
DB00333MethadoneNeuronal acetylcholine receptor subunit alpha-4target
DB00333MethadoneNeuronal acetylcholine receptor subunit beta-2target
DB00333MethadoneCytochrome P450 3A Subfamilyenzyme
DB00333MethadoneUDP-glucuronosyltransferase 2B4enzyme
DB11793NiraparibPoly [ADP-ribose] polymerase 1target
DB11793NiraparibPoly [ADP-ribose] polymerase 2target
DB11793NiraparibCarboxylesteraseenzyme
DB11793NiraparibCytochrome P450 1A2enzyme
DB11793NiraparibATP-binding cassette sub-family G member 2transporter
DB11793NiraparibMultidrug and toxin extrusion protein 1transporter
DB11793NiraparibMultidrug and toxin extrusion protein 2transporter
DB11793NiraparibP-glycoprotein 1transporter
DB11793NiraparibSerum albumincarrier
DB09074OlaparibPoly [ADP-ribose] polymerase 1target
DB09074OlaparibCytochrome P450 3A4enzyme
DB09074OlaparibCytochrome P450 2B6enzyme
DB09074OlaparibPoly [ADP-ribose] polymerase 2target
DB09074OlaparibPoly [ADP-ribose] polymerase 3target
DB09074OlaparibCytochrome P450 3A5enzyme
DB09074OlaparibP-glycoprotein 1transporter
DB09074OlaparibATP-binding cassette sub-family G member 2transporter
DB09074OlaparibAldo-keto reductase family 1 member C3target
DB09074OlaparibUDP-glucuronosyltransferase 1-1enzyme
DB09074OlaparibSerum albumincarrier
DB09074OlaparibAlpha-1-acid glycoprotein 1carrier
DB12332RucaparibPoly [ADP-ribose] polymerase 1target
DB12332RucaparibPoly [ADP-ribose] polymerase 2target
DB12332RucaparibPoly [ADP-ribose] polymerase 3target
DB12332RucaparibCytochrome P450 2D6enzyme
DB12332RucaparibCytochrome P450 1A2enzyme
DB12332RucaparibCytochrome P450 3A4enzyme
DB12332RucaparibP-glycoprotein 1transporter
DB12332RucaparibATP-binding cassette sub-family G member 2transporter
DB12332RucaparibMultidrug and toxin extrusion protein 1transporter
DB12332RucaparibMultidrug and toxin extrusion protein 2transporter
DB12332RucaparibSolute carrier family 22 member 1transporter
DB12332RucaparibMultidrug resistance-associated protein 4transporter
DB12332RucaparibSolute carrier organic anion transporter family member 1B1transporter
DB12332RucaparibSolute carrier organic anion transporter family member 1B3transporter
DB12332RucaparibSolute carrier family 22 member 6transporter
DB12332RucaparibSolute carrier family 22 member 8transporter
DB12332RucaparibCytochrome P450 3A5enzyme
DB12332RucaparibCytochrome P450 3A7enzyme
DB12332RucaparibCytochrome P450 3A43enzyme
DB12332RucaparibCytochrome P450 2C19enzyme
DB12332RucaparibCytochrome P450 2C9enzyme
DB12332RucaparibCytochrome P450 2C8enzyme
DB12332RucaparibUDP-glucuronosyltransferase 1-1enzyme
DB00421SpironolactoneMineralocorticoid receptortarget
DB00421SpironolactoneCytochrome P450 2C8enzyme
DB00421SpironolactoneCanalicular multispecific organic anion transporter 1transporter
DB00421SpironolactoneP-glycoprotein 1transporter
DB00421SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
DB00421SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
DB00421SpironolactoneAndrogen receptortarget
DB00421SpironolactoneProgesterone receptortarget
DB00421SpironolactoneGlucocorticoid receptortarget
DB00421SpironolactoneNuclear receptor subfamily 1 group I member 2target
DB00421SpironolactoneBile salt export pumptransporter
DB00421SpironolactoneSerum albumincarrier
DB00421Spironolactonealpha1-acid glycoproteincarrier
DB00421SpironolactoneEstrogen receptortarget
DB00421SpironolactoneCytochrome P450 11B2, mitochondrialenzyme
DB00421SpironolactoneVoltage-dependent L-type calcium channeltarget
DrugDrug NamePhaseStatusCount
DB00993Azathioprine4Recruiting1
DB18312Telitacicept4Recruiting1
DB00993AzathioprineNot AvailableRecruiting1
DB01097LeflunomideNot AvailableRecruiting1