Mycosis Fungoides (MF) (DBCOND0057197)

Identifiers

Synonyms
CTCL/ Mycosis Fungoides / Mycosis Fungoides / Mycosis fungoides, unspecified site / Mycoses fungoides / Mycosis fungoides NOS / Mycosis fungoides (morphologic abnormality) / Mycosis fungoides (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Betamethasone
A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Bupivacaine
A local anesthetic used in a wide variety of superficial and invasive procedures.
Carmustine
An alkylating agent used in the treatment of various malignancies, including brain tumours and multiple myeloma, among others.
Cortisone acetate
A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Doxorubicin
A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.
Hydrocortisone
A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Hydrocortisone succinate
A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Mechlorethamine
An antineoplastic agent used to treat Hodgkin's disease, lymphosarcoma, and chronic myelocytic or lymphocytic leukemia.
Methotrexate
An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
Methylprednisolone
A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
Methylprednisolone hemisuccinate
A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders.
Pentostatin
An adenosine deaminase inhibitor used to treat hairy cell leukemia.
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Prednisone
A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Triamcinolone
A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06470451
Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCLtreatment3not_yet_recruiting
NCT04491825
Diagnostic Classifier for Cutaneous T-cell LymphomasNo drug interventionsNot AvailableNot Availableunknown_status
NCT01579318
Phase II Intratumoral IL12 Plasmid Electroporation in Cutaneous Lymphomatreatment2terminated
NCT02580552
Safety, Tolerability and Pharmacokinetics of MRG-106 in Patients With Mycosis Fungoides (MF), CLL, DLBCL or ATLLtreatment1completed
NCT04676087
Mogamulizumab and Extracorporeal Photopheresis for the Treatment of Sezary Syndrome or Mycosis Fungoidestreatment1 / 2terminated
NCT02811783
Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCLtreatment3terminated
NCT03398161
Ultra Low Dose Radiation Therapy in Treating Patients With Mycosis FungoidesNo drug interventionstreatment2recruiting
NCT06421571
The Mechanism of Action of Chlormethine (CL) Gel in the Treatment of MF-CTCL Adult PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03695471
Pembrolizumab in Treating Patients With Stage IB-IV Mycosis Fungoidestreatment2active_not_recruiting
NCT05538988
BIOmarker-guided Study to Evaluate the Efficacy and Safety of cemipLimab for advancEd Cutaneous T-cell Lymphomatreatment1 / 2not_yet_recruiting
NCT00129415
Ultraviolet (UVA and UVB) Light Therapy in the Treatment of Inflammatory Skin ConditionsNo drug interventionstreatment1 / 2terminated
NCT00254332
Effect of Denileukin Diftitox on Immune System in CTCL PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00535470
An Open Label Study to Evaluate the Safety and Efficacy of Mechlorethamine(MCH) 0.04% Formulation in Mycosis Fungoidestreatment2completed
NCT02943642
Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoidestreatment2unknown_status
NCT01578499
A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)treatment3completed
NCT02881749
Low Dose Total Skin Electron Beam Treatment (TSEBT) Followed by Maintenance Valchlor for Patients With Mycosis Fungoidestreatment2unknown_status
NCT01134341
Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphomatreatment1completed
NCT04541017
Testing the Addition of an Anti-cancer Drug, Hu5F9-G4 (Magrolimab), to the Usual Chemotherapy Treatment (Mogamulizumab) in T-Cell (a Type of Immune Cell) Lymphoma That Has Returned After Treatment or Does Not Respond to Treatmenttreatment1 / 2active_not_recruiting
NCT02542124
NM-IL-12 in Cutaneous T-Cell Lymphoma (CTCL) Undergoing Total Skin Electron Beam Therapy (TSEBT)treatment2unknown_status
NCT01609816
Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin Lymphomatreatment1terminated
NCT05138458
A Study of MT-101 in Subjects With CD5+ Relapsed/Refractory TCLNo drug interventionstreatment1 / 2suspended
NCT05680558
Photopheresis in Early-stage Mycosis Fungoidestreatment2recruiting
NCT00221039
Photopheresis as an Interventional Therapy for the Treatment of CTCL (Cutaneous T-Cell Lymphoma, Mycosis Fungoides) Stage 1A, 1B, 2Atreatment4completed
NCT05904522
Histopathological Changes in Mycosis FungoidesNo drug interventionsdiagnosticNot Availablerecruiting
NCT04234048
Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphomatreatment1recruiting
NCT03380026
Mechlorethamine Induced Contact Dermatitis Avoidance Studysupportive_care2completed
NCT02848274
ID Of Prognostic Factors In Mycosis Fungoides/Sezary SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT00157274
Study of Alemtuzumab to Treat Advanced Mycosis Fungoides/Sezary Syndrometreatment2unknown_status
NCT04185220
Phase I Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for People With Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrometreatment1completed
NCT00038376
Phase II Study Of Roferon and Accutane For Patients With T-Cell Malignanciestreatment2completed
NCT05855460
Estimation of the Tissue and Serum Levels of Interleukin (IL) -35 in Mycosis Fungoides: a Case Control StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05357794
Effectiveness of Concurrent Ultra-Low-Dose Total-Skin Electron Beam Therapy and Brentuximab Vedotin Given Quarterly Over 12 Months for Patients With Mycosis Fungoidestreatment2recruiting
NCT04955340
A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of [14C]-Resminostattreatment1completed
NCT01445340
Topical Romidepsin to Treat Early-Stage Cutaneous T-Cell Lymphomatreatment1terminated
NCT02890368
Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoidestreatment1terminated
NCT00177268
Blood, Urine, and Tissue Collection for Cutaneous Lymphoma, Eczema, and Atopic Dermatitis ResearchNo drug interventionsNot AvailableNot Availablerecruiting
NCT00611208
A-dmDT390-bisFv(UCHT1) Immunotoxin Therapy for Patients With Cutaneous T-Cell Lymphoma (CTCL)treatment2completed
NCT05526638
Serum and Tissue Level of Interleukin-15 (IL-15) and IL-15 Receptor Alpha (IL-15Rα) in Mycosis FungoidesNo drug interventionsdiagnosticNot Availablerecruiting
NCT00496743
Study of Low-Dose Total Skin Electron Beam Therapy in Mycosis FungoidesNo drug interventionstreatmentNot Availableterminated
NCT00177190
In Vitro Evaluation of Immune Responses in Cutaneous T-Cell Lymphoma (CTCL)No drug interventionsNot AvailableNot Availablecompleted
NCT03789864
Biodynamic Imaging Utility in Predicting Response to Gemcitabine Chemotherapy in Mycosis FungoidesNo drug interventionsdevice_feasibilityNot Availableterminated
NCT00168064
Safety and Efficacy of Nitrogen Mustard in Treatment of Mycosis Fungoidestreatment2completed
NCT05205902
TOtal Skin Electron Beam Therapy (Low-dose) for Tumor Clone Eradication in Early-stage Mycosis FungoidesNo drug interventionsother3not_yet_recruiting
NCT05872854
Treatment of Mycosis Fungoides With Hypericin Ointment and Visible Lighttreatment2recruiting
NCT01556828
Analysis of Cutaneous and Hematologic Disorders by High-Throughput Nucleic Acid SequencingNo drug interventionsNot AvailableNot Availableterminated
NCT00226993
Phase I/II Study of Intratumoral Injection of CPG 7909, a TLR9 Agonist, Combined With Local Radiation for Patients With Recurrent Mycosis Fungoides.treatment1 / 2withdrawn
NCT03267407
Vietnam Cryptococcal Retention in Care Study - Version 2.1No drug interventionsNot AvailableNot Availableunknown_status
NCT02341209
Doxycycline for the Treatment of Cutaneous T-Cell Lymphomatreatment2terminated
NCT02652715
Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin LymphomaNo drug interventionsbasic_scienceNot Availablecompleted
NCT01590732
Romidepsin, Ifosfamide, Carboplatin, and Etoposide in Treating Participants With Relapsed or Refractory Peripheral T-Cell Lymphomatreatment1completed
NCT05414500
Mogamulizumab and Brentuximab Vedotin in CTCL and Mycosis Fungoidestreatment1recruiting
NCT00091559
Oral SAHA (Suberoylanilide Hydroxamic Acid) in Advanced Cutaneous T-cell Lymphoma (0683-001)treatment2completed
NCT02323659
Comparison of Methotrexate Versus Interferon-alfa 2b in Patients With Primary Cutaneous T-cell Lymphomastreatment4terminated
NCT01396070
Brentuximab Vedotin (SGN-35) in Patients With Mycosis Fungoides With Variable CD30 Expression Leveltreatment2completed
NCT00050999
Study of ONTAK (Denileukin Diftitox) in Cutaneous T-Cell Lymphoma (CTCL) Patientstreatment4completed
NCT05838599
Combining Topical Imiquimod With Local Radiotherapy for Treatment of Mycosis Fungoidestreatment0recruiting
NCT04960618
Pembrolizumab in Combination With Gemcitabine in People With Advanced Mycosis Fungoides or Sézary Syndrometreatment2recruiting
NCT03288818
Low Dose Total Skin Electron Beam Radiation Therapy and Mechlorethamine Hydrochloride Gel in Treating Patients With Mycosis Fungoidestreatment2withdrawn
NCT04256018
Mogamulizumab + Low-Dose Total Skin Electron Beam Tx in Mycosis Fungoides & Sézary Syndrometreatment2recruiting
NCT00178841
Combination Drug Study of Bexarotene and Rosiglitazone to Treat CTCLtreatment2completed
NCT05978141
A Registry for People With T-cell LymphomaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02883517
Cell-free Circulating DNA in Primary Cutaneous LymphomasNo drug interventionsNot AvailableNot Availablecompleted
NCT05879458
Ritlecitinib in CTCLtreatment2recruiting
NCT03905135
Interleukin-15 (IL-5) in Combination With Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignanciestreatment1completed
NCT06508463
Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphomatreatment1recruiting
NCT02822586
TSEB and Brentuximab for Treatment of Mycosis Fungoides & Sezary Syndrometreatment1completed
NCT03602157
Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCLtreatment1recruiting
NCT00185965
CPG 7909 + Local Radiotherapy in Recurrent Low-Grade Lymphomastreatment1 / 2completed
NCT01352520
SGN-35 in CD30-positive Lymphoproliferative Disorders (ALCL), Mycosis Fungoides (MF), and Extensive Lymphomatoid Papulosis (LyP)treatment2active_not_recruiting
NCT00047060
Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrometreatment1 / 2completed
NCT02301494
Effectiveness of Imiquimod Topical Cream in Early Stage Cutaneous T-cell LymphomatreatmentNot Availablewithdrawn
NCT05944562
Tulmimetostat (CPI-0209) in Patients With Mycosis Fungoides and Sézary SyndromeNo drug interventionstreatment1recruiting
NCT05303480
Deep Phenotyping of Cutaneous T Cell Lymphoma, Type Mycosis FungoidestreatmentNot Availablecompleted
NCT03587844
Dosing of Brentuximab Vedotin for Mycosis Fungoides, Sezary Syndrome Patientstreatment2recruiting
NCT00985140
Phase 2 Total Skin Electron Beam Therapy (TSEBT 12 Gy) in Stage IB-IIIA Mycosis FungoidesNo drug interventionsNot AvailableNot Availableterminated
NCT02953301
Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS)treatment2completed
NCT04118868
Pembrolizumab Administered Via the Sofusa® DoseConnect™ in Patients With Relapsed/Refractory Cutaneous T-cell Lymphoma.treatment1recruiting
NCT04904146
Predictive and Prognostic Biomarkers in Patients With Mycosis Fungoides and Sézary Syndrome.No drug interventionsNot AvailableNot Availablerecruiting
NCT06207812
Long-term Outcomes Associated With Juvenile-onset Mycosis Fungoides and Lymphomatoid PapulosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT00051012
Study of ONTAK (Denileukin Diftitox) in Previously Treated Cutaneous T-Cell Lymphoma Patientstreatment4completed
NCT00127881
Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sezary Syndrometreatment3terminated
NCT06235281
Phototherapy and Mogamulizumab in Early Stage MF (PLIGHT)treatment0recruiting
NCT02296164
Clinical Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell LymphomaNot AvailableNot Availablecompleted
NCT00368784
T Cell Repertoire Analysis of Immune Mediated Skin DiseasesNo drug interventionsNot AvailableNot Availablecompleted