Malaria caused by Plasmodium falciparum (DBCOND0021343)

Identifiers

Synonyms
Falciparum; Malaria / Malaria Falciparum / Malaria, Falciparum / Malaria,Falciparum / Falciparum Malaria / Malaria caused by plasmodium falciparum / Plasmodium falciparum malaria, unspecified / Falciparum malaria (disorder) / Falciparum malaria (malignant tertian) / Plasmodium falciparum malaria / Malignant tertian fever (finding) / Plasmodium falciparum infection

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Artemisinin
A medication indicated in the treatment of malaria.
Artenimol
For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941.
Atovaquone
An antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
Clindamycin
A lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
Doxycycline
A tetracycline antibiotic used to treat a wide variety of bacterial infections.
Mefloquine
An antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.
Piperaquine
For the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
Proguanil
A medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
Quinidine
A medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
Sulfadiazine
A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid.
Sulfadoxine
A long acting sulfonamide used for the treatment or prevention of malaria.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06347471
The Transmission of Artemisinin Resistant Parasites Before and After Conventional Artemisinin-combination Therapytreatment4recruiting
NCT06652737
Age De-escalation Safety Trial of PfSPZ-LARC2 Vaccine in Burkina FasoNo drug interventionstreatment1not_yet_recruiting
NCT00928083
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female Subjectstreatment1completed
NCT00164216
Efficacy and Effectiveness of Combined Therapy for Uncomplicated Malaria Treatment in PeruNot AvailableNot Availablecompleted
NCT05878366
Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC)No drug interventionsotherNot Availablecompleted
NCT06558643
Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV371 LAI in Healthy ParticipantsNo drug interventionstreatment1recruiting
NCT06083688
Preventing Malaria in School Children to Protect the Whole Community in Rural Blantyre District, Malawiprevention4recruiting
NCT06320535
A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™prevention1recruiting
NCT06413108
Safety, Pharmacokinetics, and Plasmodium Falciparum Transmission-reducing Activity of Monoclonal Antibody TB31F in MaliNo drug interventionsother1 / 2recruiting
NCT05550909
Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Malitreatment2completed
NCT06141057
A Study to Compare Two Dosing Regimens for a New Malaria Vaccinetreatment1active_not_recruiting
NCT06618885
Safety and Immunogenicity of SUM-101 Malaria Vaccine in Children and Infants Living in Burkina FasoNo drug interventionsprevention1not_yet_recruiting
NCT04565184
Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaoundetreatment4completed
NCT04079621
Short Course Radical Cure of P. Vivax Malaria in Nepaltreatment4completed
NCT03947190
A Study to Determine if New Types of Malaria Vaccines Are Safe, Effective and Lead to Immunity in Kenyan Adultstreatment2unknown_status
NCT05604521
A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMINo drug interventionsprevention1terminated
NCT03355664
Study to Compare the Triple ACT AL+AQ With the ACT AL in Cambodia and VietnamNo drug interventionstreatment3completed
NCT02084602
Assessment of Artesunate/Mefloquine in the Peruvian Amazontreatment4completed
NCT06036030
Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papuatreatment2completed
NCT05958693
TES of Artemether-lumefantrine for Pf in the Philippines in 2015Not AvailableNot Availablecompleted
NCT05287893
Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malariaother1completed
NCT05060198
Therapeutic Efficacy Study of AL and DP in Western KenyatreatmentNot Availablecompleted
NCT04969185
Association Between Drug Levels, Malaria, and Antimalarial Resistance in the Setting of Seasonal Malaria ChemopreventionNo drug interventionsNot AvailableNot Availablecompleted
NCT04858087
Malawi International Center of Excellence in Malaria Research School-based CohortNo drug interventionsNot AvailableNot Availablecompleted
NCT06337253
Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambiqueprevention4not_yet_recruiting
NCT03882528
Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54No drug interventionsscreening1completed
NCT03580824
A Study to Determine if a New Malaria Vaccine is Safe and Induces Immunity Among Kenyan Adults, Young Children and Infantstreatment1 / 2completed
NCT03195387
Chemoprotective Activity of MMV390048 in PfSPZ Challenge ModelNo drug interventionsprevention1withdrawn
NCT05567016
CHILD (Child Health and Infection With Low Density) MalariaNo drug interventionspreventionNot Availableactive_not_recruiting
NCT05244954
Comparing Chemoprevention Approaches for School-based Malaria Controlprevention4completed
NCT05252845
Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adultsprevention2completed
NCT05685875
Association of Diabetes and Metabolic Syndrome With Severe Malaria in CameroonNo drug interventionsNot AvailableNot Availablerecruiting
NCT04310085
Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoitestreatment1completed
NCT03138096
Safety and Protective Efficacy of Pb(PfCS@UIS4)No drug interventionsprevention1 / 2completed
NCT02987270
Evaluation of Community-based Mass Screening and Treatment for Malaria in Western Kenyatreatment3completed
NCT04271306
Safety, Immunogenicity and ex Vivo Efficacy of Pfs25-IMX313/Matrix-M in Healthy Volunteers in Bagamoyo, Tanzania.treatment1unknown_status
NCT04251351
Effect of Paracetamol on Kidney Function in Severe Malariaprevention3recruiting
NCT00677833
Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africatreatment2 / 3completed
NCT00137553
The Efficacy of Re-treatment With Sulfadoxine-pyrimethamine in Childrentreatment4completed
NCT01163877
Iron Absorption and Utilization in Adolescents Infected With Malaria Parasites, Hookworms or SchistosomaNo drug interventionsbasic_scienceNot Availablecompleted
NCT02448745
Liberia Insecticide Treated Durable Wall Linings Study: Protocol for a Cluster Randomised Trial (DL)No drug interventionspreventionNot Availablecompleted
NCT00374998
Safety and Immunogenicity Study of the Malaria Vaccines FP9 PP and MVA PPNo drug interventionsprevention1completed
NCT00509015
Mass-Drug Administration to Reduce Malaria TransmissionpreventionNot Availablecompleted
NCT02434952
Safety and Tolerability of Low Dose Primaquinetreatment4completed
NCT00164359
Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in Malawitreatment4completed
NCT00126906
Prevention of Malaria During Pregnancy Using Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine: Malawieducational_counseling_trainingNot Availablecompleted
NCT00344006
Chlorproguanil-Dapsone-Artesunate Versus COARTEM For Uncomplicated Malariatreatment3completed
NCT01713517
Impact of Insecticide Resistance on Vector ControlNo drug interventionsprevention4unknown_status
NCT00371735
Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malariatreatment3completed
NCT00082563
Azithromycin in Combination With Chloroquine Versus Chloroquine in the Eradication of Asymptomatic Plasmodium Falciparumtreatment2terminated
NCT00426439
Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissautreatment4completed
NCT01108939
Study of Iron Absorption and Utilization in Asymptomatic MalariaNo drug interventionstreatment0completed
NCT01103830
Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteerstreatment1completed
NCT06524336
Host Immune Dynamics Following Seasonal Malaria Chemoprevention in African ChildrenNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT06424002
The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Childrenprevention4not_yet_recruiting
NCT05979207
Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. FalciparumNo drug interventionstreatment1completed
NCT05978037
A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccinesprevention1 / 2recruiting
NCT05980156
Comparing Chemoprevention Drugs for School-based Malaria Controlprevention4completed
NCT05958810
TES of Artemether-lumefantrine for Pf in the Philippines in 2017-2018Not AvailableNot Availablecompleted
NCT05801198
Addressing Asymptomatic Plasmodium Reservoirs to Accelerate Malaria Elimination and Eradication in Rwanda.No drug interventionstreatment2not_yet_recruiting
NCT05507970
First-in-Human Study to Assess the Safety, Tolerability and Pharmacokinetics of MMV367No drug interventionstreatment1completed
NCT05468606
Coadministration of GA2 Sporozoites With Adjuvantsprevention0recruiting
NCT05081089
Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Malitreatment2completed
NCT05058885
Plasmodium Vivax Among Duffy Negative Population in Cameroon.No drug interventionsNot AvailableNot Availablerecruiting
NCT04864444
Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination ActivitiespreventionNot Availablecompleted
NCT04844905
Adjunctive Ivermectin Mass Drug Administration for Malaria Controltreatment3unknown_status
NCT04318002
Safety and Immunogenicity of RH5.1/Matrix-M in Adults and Infants Living in Tanzaniaprevention1active_not_recruiting
NCT04289688
Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR CongoNo drug interventionsNot AvailableNot Availablecompleted
NCT04149106
Seasonal Malaria Chemoprevention With Dihydroartemisin Piperaquin vs. Sulfadoxine-pyrimethamin+Amodiaquinprevention3active_not_recruiting
NCT03640403
Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzaniaprevention3unknown_status
NCT03511443
Evaluation of the Performance of a hsRDT Versus cRDT in Reactive Case Detection of Malaria InfectionsNo drug interventionsdiagnosticNot Availableunknown_status
NCT03201770
Cohort Event Monitoring Study of Pyramax®treatment4completed
NCT05125133
Evaluation of Insecticide-treated Eave Nets and Window Screens for Malaria Control in Tanzania.No drug interventionspreventionNot Availableunknown_status
NCT05135273
Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in Maliprevention1completed
NCT05197751
MSP3-CRM-Vac4All/ Alhydrogel® Malaria VaccineNo drug interventionsprevention1active_not_recruiting
NCT05676645
Pharmacokinetics of Antimalarials in Breastfeeding Ugandan Mother-infant PairsNot AvailableNot Availableactive_not_recruiting
NCT05757167
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnosticsscreening4recruiting
NCT03178643
Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)prevention4completed
NCT03435874
Safety and Immunogenicity of ChAd63 RH5 and MVA RH5 in Adults, Young Children and Infants Living in Tanzaniaprevention1completed
NCT03420053
Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian AdultsNo drug interventionsprevention1completed
NCT03241901
"Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania"treatment4completed
NCT01992900
A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malariatreatment2completed
NCT01325974
Time to Become Negative of Three Rapid Diagnostic Tests for MalariaNo drug interventionsNot AvailableNot Availablecompleted
NCT00084227
Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South Americatreatment2 / 3completed
NCT01160562
Pilot Study to Estimate the Burden and Distribution of Plasmodium Falciparum Malaria in Kalifabougou, Mali in Preparation for a Prospective Cohort Study of Naturally-Acquired Malaria ImmunityNo drug interventionsNot AvailableNot Availablecompleted
NCT02325180
Artemisinin-based Combination Therapy for Treatment of Plasmodium Falciparum Malaria in North Sumatera, Indonesiatreatment4completed
NCT01944189
Artemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population PharmacokineticsNo drug interventionssupportive_care4unknown_status
NCT01783340
Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxisprevention1 / 2withdrawn
NCT00084240
Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asiatreatment2 / 3terminated
NCT02329301
Mass Drug Administration With Dihydroartemisinin + Piperaquine for Reducing Malaria in Southern ZambiatreatmentNot Availablecompleted
NCT00152204
The Community Effectiveness of IPTi in Southern Tanzaniaprevention3unknown_status
NCT01442168
Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum Malariatreatment1 / 2terminated
NCT00147368
Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malariatreatment1 / 2completed
NCT00142246
Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education.prevention3completed
NCT00223990
Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccineprevention2completed
NCT00885287
Interactions Between Artemether-lumefantrine and Antiretrovirals in HIV-patients With Uncomplicated Malaria in Tanzaniatreatment4completed
NCT01660854
Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum Sporozoitesbasic_scienceNot Availablecompleted
NCT01326754
Efficacy of Artemether-lumefantrine, Artesunate-amodiaquine and Dihydroartemisinin-piperaquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria in MalawitreatmentNot Availablecompleted
NCT01556945
Safety and Preliminary Efficacy of the Malaria Vaccine Candidates Falciparum Merozoite Protein-1 (FMP1) and SmithKlineBeecham (SKBB) Candidate Malaria Vaccine RTS,SNo drug interventionsprevention1 / 2completed
NCT04609098
Single Low Dose Tafenoquine to Reduce P. Falciparum Transmission in Mali (NECTAR2)treatment2completed
NCT00374205
Randomized Trial on Effectiveness of ACTs in Ghanatreatment4terminated
NCT02637128
In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malariatreatment4completed
NCT00375128
Sporozoite Challenge of Polyprotein VaccineesNo drug interventionsprevention1 / 2completed
NCT01204411
Efficacy of Artesunate-amodiaquine (AS-AQ) in Children With Malaria and Severe Acute Malnutrition, Madaoua, Niger 2010treatment4withdrawn
NCT05385471
A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of the Blood-stage Malaria Candidate Vaccines RH5.1 in Matrix-M and R78C in Matrix-M in Healthy UK Adultsprevention0recruiting
NCT02737007
A Microdose Study in Healthy Subjects to Describe Intravenous Pharmacokinetics of GSK3191607No drug interventionstreatment1completed
NCT00142207
Preventing Malaria During Pregnancy in Epidemic-prone Areas.prevention3completed
NCT00157885
A Randomised Trial of Artekin and Artesunate & Amodiaquine for Uncomplicated Malaria in Timika, Papua, Indonesia.treatmentNot Availablecompleted
NCT01829737
Malaria Transmission Studies in MaliNo drug interventionsNot AvailableNot Availablecompleted
NCT04839900
Proactive Community Case Management for Malaria in ZambiaNo drug interventionstreatmentNot Availablecompleted
NCT00951106
Therapeutic Efficacy Study of Pyrimethamine/Sulfdoxine (Fansidar®) for the Treatment of Uncomplicated Falciparum Malaria in the Peruvian AmazontreatmentNot Availablecompleted
NCT00479206
Artemisinin Resistance in CambodiatreatmentNot Availablecompleted
NCT01222949
A Pharmacokinetic (PK) Trial in Healthy Asian and Caucasian Volunteers Investigating the PK Profile of Eurartesim™treatment1completed
NCT06572644
Performance of an Ultrasensible Malaria Rapid Diagnostic Test Among Pregnant Women in Burkina FasoNo drug interventionsNot AvailableNot Availablecompleted
NCT05790889
A Study to Test Experimental Blood Stage Malaria Vaccine in Burkina Faso.prevention1 / 2recruiting
NCT05776017
MSP3-CRM-Vac4All/ Alhydrogel® Vaccineprevention1 / 2recruiting
NCT05306067
Plasmodium Falciparum Genomic Intelligence in MozambiqueNo drug interventionsNot AvailableNot Availablecompleted
NCT05150808
Vectron T500 (Broflanilide 50WP) for IRS in Tanzania TanzaniaNo drug interventionsprevention3unknown_status
NCT04940130
PfSPZ Vaccine Trial in Malian ChildrenNo drug interventionsprevention2completed
NCT04862416
Safety and Efficacy of R0.6C VaccineNo drug interventionsprevention1completed
NCT04800055
Attractive Targeted Sugar Bait Phase III Trial in ZambiaNo drug interventionspreventionNot Availableactive_not_recruiting
NCT04473768
Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT04319380
Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ) Extension StudyNo drug interventionsprevention3completed
NCT04238689
Safety, Tolerability, and Pharmacokinetics and Pharmacodynamics of TB31FNo drug interventionsprevention1completed
NCT04130282
VAC077: Safety and Immunogenicity of the Pfs25-IMX313/Matrix-M Vaccineprevention1terminated
NCT04049916
Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmissiontreatment2 / 3completed
NCT03896724
Safety, Immunogenicity and Efficacy of R21 Matrix-M in 5-17 Month Old Children in Nanoro, Burkina Fasotreatment1 / 2completed
NCT03813108
Safety and Efficacy of NF135 CPS ImmunizationpreventionNot Availableterminated
NCT03806465
Malaria Vaccine Pilot EvaluationNo drug interventionsNot AvailableNot Availableunknown_status
NCT03814616
Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfectionstreatment2unknown_status
NCT03176719
Non-specific Effects of Vaccination on Mortality and MorbidityNo drug interventionsNot AvailableNot Availableunknown_status
NCT06293339
Durability of Protection After Single Immunisation With GA2 Sporozoites (CoGA-Rechallenge)No drug interventionsprevention1not_yet_recruiting
NCT03143218
Seasonal Malaria Vaccination (RTS,S/AS01) and Seasonal Malaria Chemoprevention (SP/AQ)prevention3completed
NCT03454048
Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2otherNot Availablecompleted
NCT03867331
To Assess the Safety, Immunogenicity and Efficacy of VLPM01 in Healthy, Malaria-Naïve VolunteersNo drug interventionsprevention1completed
NCT00378625
Efficacy, Effect on Gametocytes and Tolerability of the Addition of Artesunate to Amodiaquine in ColombiaNot Available3completed
NCT04280692
Controlled Human Malaria Infection Transmission Model - Phase Abasic_science1 / 2suspended
NCT06171113
A Study to Investigate the Safety of GSK4024484 in Healthy Adult ParticipantsNo drug interventionstreatment1recruiting
NCT02389439
Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malariatreatment2completed
NCT01213966
Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infectiontreatment2completed
NCT01930331
Safety, Tolerability, Pharmacokinetics and Efficacy of ARCOtreatment4completed
NCT02014727
Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adultstreatment1completed
NCT00082576
Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africatreatment2 / 3completed
NCT01222962
Food Interaction Study on the Pharmacokinetics of Eurartesim™ (DHA and PQP)in Healthy Male Adult Volunteerstreatment1completed
NCT04709692
Efficacy of SJ733 in Adults With Uncomplicated Plasmodium Falciparum or Vivax Malariatreatment2completed
NCT02281344
MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy ParticipantsNo drug interventionsbasic_science1terminated
NCT00529867
Randomised Efficacy Study of Two Artemether-Lumefantrine Oral Formulations for the Treatment of Uncomplicated P. Falciparum Malariatreatment4completed
NCT00408668
Efficacy of Combined PEV3A Virosomal Vaccine and FP9-MVA ME-TRAP Prime Boost Regimenprevention1 / 2completed
NCT00164710
Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawitreatment4completed
NCT00137514
Chloroquine and Amodiaquine for Treatment of Malaria in Childrentreatment4completed
NCT01567423
Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated MalariatreatmentNot Availablecompleted
NCT01019408
Extended-dose Chloroquine (ECQ) for Resistant Falciparum Malaria Among Afghan Refugees in Pakistantreatment4completed
NCT02453308
A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC)No drug interventionstreatment2 / 3completed
NCT02851108
Methylene Blue Against Falciparum Malaria in Burkina Fasotreatment2completed
NCT05911828
A Study to Determine Safety, Tolerability, and Pharmacokinetics of Different Orally Administered Regimens of the Combination ZY19489-Ferroquine in Adult Asymptomatic Plasmodium Falciparum Carrierstreatment1recruiting
NCT00149383
Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malariatreatment1 / 2completed
NCT00859807
A Bioequivalence Study Comparing Camoquin® Suspension (Pfizer) To Flavoquine® Tablets (Sanofi Aventis) In Healthy Subjectstreatment4completed
NCT01350856
Tracking Resistance to Artemisinin (TRAC)treatment4completed
NCT04422015
Biological Mechanisms in Afebrile P. Falciparum MalariaNo drug interventionsNot AvailableNot Availablecompleted
NCT00440752
The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT00157859
To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, IndonesiatreatmentNot Availablecompleted
NCT01047436
Efficacy of ArTiMist™ in Childrentreatment2completed
NCT00282919
A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malariatreatment2completed
NCT04289558
Nitrite Infusion in Children With Malariatreatment1withdrawn
NCT00493363
Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western CambodiatreatmentNot Availablecompleted
NCT00158548
ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistantreatment3completed
NCT00894660
A Bioequivalence Study Comparing Amodiaquine Tablet (Pfizer) To Amodiaquine Tablets (Arsuamoon-Guilin China) In Healthy Subjectsbasic_science1completed
NCT00513669
Phase Ib Trial of Two Virosome Formulated Malaria Vaccine Components (PEV 301, PEV 302) in TanzaniaNo drug interventionsprevention1completed
NCT04829695
Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroontreatment4unknown_status
NCT03916003
Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areastreatment4completed
NCT01144702
Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium Falciparumtreatment2 / 3completed
NCT00157833
A Randomized Trial of Coartemether and Artekin for the Treatment of Uncomplicated Malaria in Papua, Indonesia.No drug interventionstreatmentNot Availablecompleted
NCT00442377
Study to Investigate the Induction of an Protective Immune Response to MalariaNo drug interventionspreventionNot Availablecompleted
NCT01365598
Evaluation of the Gametocytocidal Efficacy and Safety of Primaquine in Uncomplicated Falciparum Malaria in Ugandaprevention3completed
NCT04222088
TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014Not AvailableNot Availablecompleted
NCT00459615
Phase II Dose Ranging Study of Artesunatetreatment2completed
NCT06529237
Malaria Molecular Surveillance in Mozambique (Phase 2)No drug interventionsNot AvailableNot Availablerecruiting
NCT01115439
Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum MalariaNot AvailableNot Availablecompleted
NCT01374126
Azithromycin Combination Therapy for the Treatment of Severe Malariatreatment2completed
NCT00894374
Bioequivalence Study Comparing Artesunate Tablet To Arsuamoon® Tablets (Guilin-China) In Healthy Subjectsbasic_science1completed
NCT00403260
Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patientstreatment3completed
NCT00400101
Phase Ia Malaria Vaccine Trial of Two Virosome-Formulated PeptidesNo drug interventionsprevention1terminated
NCT00722150
Artemisinin Resistance in Cambodia IItreatmentNot Availablecompleted