Folate supplementation therapy (DBCOND0024436)

Identifiers

Synonyms

Folate supplementation / Folic acid supplementation / Medicinal product acting as folic acid supplement (product) / Vitamin supplementation / Vitamin supplement therapy (regime/therapy)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Drospirenone	A progestin used in oral contraceptive pills for the prevention of pregnancy and other conditions.	Progesterone receptortarget Mineralocorticoid receptortarget Androgen receptortarget Prostaglandin G/H synthase 2enzyme Serum paraoxonase/arylesterase 1enzyme Glucocorticoid receptortarget Cytochrome P450 3A4enzyme
Ethinylestradiol	An estradiol used as a contraceptive.	Estrogen receptortarget Nuclear receptor subfamily 1 group I member 2target Cytochrome P450 3A4enzyme Cytochrome P450 2C8enzyme Bile salt export pumptransporter Hepatic sodium/bile acid cotransportertransporter ATP-binding cassette sub-family C member 2transporter ATP-dependent translocase ABCB1transporter UDP-glucuronosyltransferase 1A1enzyme Cytochrome P450 2C19enzyme UDP-glucuronosyltransferase 1A4enzyme UDP-glucuronosyltransferase 1A9enzyme Cytochrome P450 2C9enzyme Cytochrome P450 1A2enzyme Sulfotransferase 1E1enzyme Sulfotransferase 1A3enzyme Cytochrome P450 3A5enzyme UDP-glucuronosyltransferase 2B7enzyme UDP-glucuronosyltransferase 1A3enzyme Catechol O-methyltransferaseenzyme Solute carrier organic anion transporter family member 1A2transporter Albumincarrier Sex hormone-binding globulincarrier
Ferrous cysteine glycinate	An ingredient found in a variety of supplements and vitamins.	No drug targets
Flavin adenine dinucleotide	A coenzyme form of vitamin B2 used in clinical conditions associated with vitamin B2 deficiency.	p-hydroxybenzoate hydroxylasetarget Nitric oxide synthase 1target NAD(P)H dehydrogenase [quinone] 1target p-hydroxybenzoate hydroxylasetarget Fumarate reductase flavoprotein subunittarget ERO1-like protein betatarget Glutathione reductase, mitochondrialtarget NADPH-ferredoxin reductase FprAtarget NADH-cytochrome b5 reductase 3target Cholesterol oxidasetarget Thymidylate synthase ThyXtarget Pyruvate oxidasetarget Glutathione reductasetarget Monomeric sarcosine oxidasetarget Trypanothione reductasetarget Ribosyldihydronicotinamide dehydrogenase [quinone]target Isovaleryl-CoA dehydrogenase, mitochondrialtarget Xanthine dehydrogenase/oxidasetarget Cholesterol oxidasetarget Dihydropyrimidine dehydrogenase [NADP(+)]target D-lactate dehydrogenasetarget Thioredoxin reductase 1, cytoplasmictarget Isobutyryl-CoA dehydrogenase, mitochondrialtarget Apoptosis-inducing factor 1, mitochondrialtarget UDP-galactopyranose mutasetarget Flavohemoproteintarget Glycine oxidasetarget NADPH--cytochrome P450 reductasetarget Glutaryl-CoA dehydrogenase, mitochondrialtarget Medium-chain specific acyl-CoA dehydrogenase, mitochondrialtarget D-amino-acid oxidasetarget Bifunctional protein PutAtarget Deoxyribodipyrimidine photo-lyasetarget Amine oxidase [flavin-containing] Atarget Short-chain specific acyl-CoA dehydrogenase, mitochondrialtarget L-amino-acid oxidasetarget 2,4-dienoyl-CoA reductase [NADPH]target 2-oxopropyl-CoM reductase, carboxylatingtarget Fumarate reductase flavoprotein subunittarget Thioredoxin reductasetarget 5,10-methylenetetrahydrofolate reductasetarget Dimethylglycine oxidasetarget NADH peroxidasetarget Ferredoxin--NADP reductasetarget Sulfite reductase [NADPH] flavoprotein alpha-componenttarget Ferredoxin--NADP reductasetarget Acyl-CoA dehydrogenase, short-chain specifictarget Ferredoxin reductasetarget Dihydrolipoyl dehydrogenasetarget Amine oxidase, flavin-containing proteintarget Deoxyribodipyrimidine photo-lyasetarget Deoxyribodipyrimidine photo-lyasetarget L-aspartate oxidasetarget Cryptochrome DASHtarget Dihydrolipoyl dehydrogenase, mitochondrialtarget Fumarate reductase flavoprotein subunittarget NADH-cytochrome b5 reductase 1target Oxidoreductasetarget Amine oxidase [flavin-containing] Btarget NADPH:adrenodoxin oxidoreductase, mitochondrialtarget Peroxisomal acyl-coenzyme A oxidase 1target UDP-N-acetylenolpyruvoylglucosamine reductasetarget FAD-linked sulfhydryl oxidase ALRtarget UDP-N-acetylenolpyruvoylglucosamine reductasetarget Flavohemoproteintarget Phenol 2-hydroxylase component Btarget Methylenetetrahydrofolate reductasetarget Putidaredoxin reductasetarget NAD(P)H dehydrogenase (quinone)target UDP-galactopyranose mutasetarget 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerasetarget 4-cresol dehydrogenase [hydroxylating] flavoprotein subunittarget Alkyl hydroperoxide reductase subunit Ftarget Dihydrolipoyl dehydrogenasetarget Glutathione reductasetarget Phenylacetone monooxygenasetarget Benzoate 1,2-dioxygenase electron transfer componenttarget Putative acyl-CoA dehydrogenasetarget FkbItarget Dihydrolipoyl dehydrogenasetarget Dihydrolipoyl dehydrogenasetarget Alkyl hydroperoxide reductase subunit Ftarget Ferredoxin--NADP reductasetarget Ferredoxin--NADP reductasetarget Mersacidin decarboxylasetarget Amine oxidase [flavin-containing] Benzyme NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialtarget
Lutein	Xanthophylls are taken for nutritional supplementation, and also for treating dietary shortage or imbalance.	Albumincarrier
Phosphatidyl serine	A nutrient used in some supplement products.	Phosphatidylserine decarboxylase proenzyme, mitochondrialtarget Scavenger receptor class B member 1target Protein kinase C alpha typetarget Phosphatidylserine synthase 1target Diacylglycerol kinase gammatarget Diacylglycerol kinase deltatarget Phosphatidylserine synthase 2target Sphingomyelin phosphodiesterase 4target Sphingomyelin phosphodiesterase 3target Phospholipid-transporting ATPase IAtarget
Pyridoxal phosphate	A vitamin available in many formulations to correct vitamin B6 deficiency.	Cystathionine beta-synthasetarget Alanine--glyoxylate aminotransferase 2, mitochondrialtarget Glutamate decarboxylase 1target Kynureninasetarget Serine hydroxymethyltransferase, cytosolictarget Cysteine desulfurasetarget Aspartate aminotransferase, cytoplasmictarget Ornithine aminotransferase, mitochondrialtarget Ornithine decarboxylasetarget Kynurenine/alpha-aminoadipate aminotransferase, mitochondrialtarget 4-aminobutyrate aminotransferase, mitochondrialtarget Pyridoxine-5'-phosphate oxidasetarget Sphingosine-1-phosphate lyase 1target Tyrosine aminotransferasetarget Kynurenine--oxoglutarate transaminase 1target Glycogen phosphorylase, liver formtarget Serine palmitoyltransferase 2target Cysteine sulfinic acid decarboxylasetarget Histidine decarboxylasetarget Antizyme inhibitor 2target L-serine dehydratase/L-threonine deaminasetarget 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrialtarget Glycine dehydrogenase (decarboxylating), mitochondrialtarget Alanine aminotransferase 1target Phosphoserine aminotransferasetarget 5-aminolevulinate synthase, non-specific, mitochondrialtarget Alanine--glyoxylate aminotransferasetarget Chronophintarget Serine palmitoyltransferase 1target Cystathionine gamma-lyasetarget Branched-chain-amino-acid aminotransferase, cytosolictarget Branched-chain-amino-acid aminotransferase, mitochondrialtarget Pyridoxal phosphate homeostasis proteintarget Aspartate aminotransferase, mitochondrialtarget Glycogen phosphorylase, brain formtarget Glycogen phosphorylase, muscle formtarget Aromatic-L-amino-acid decarboxylasetarget Serine hydroxymethyltransferasetarget Glutamate decarboxylase 2target Kynurenine--oxoglutarate transaminase 3target Acidic amino acid decarboxylase GADL1target Selenocysteine lyasetarget Immunoglobulin superfamily member 10target 5-phosphohydroxy-L-lysine phospho-lyasetarget Serine hydroxymethyltransferase, mitochondrialtarget 5-aminolevulinate synthase, erythroid-specific, mitochondrialtarget Alanine aminotransferase 2target Molybdenum cofactor sulfurasetarget Serine dehydratase-liketarget Serine racemasetarget O-phosphoseryl-tRNA(Sec) selenium transferasetarget Serine palmitoyltransferase 3target Glutamic acid decarboxylasetarget Aspartate aminotransferasetarget Prothrombintarget

Clinical Trials

Not Available