Alimentary Tract and Metabolism

Name
Alimentary Tract and Metabolism
Accession Number
DBCAT002118
Description

Not Available

Drugs
DrugDrug Description
AcarboseAn alpha-glucosidase inhibitor used in adjunctly with diet and exercise for the management of glycemic control in patients with type 2 diabetes mellitus.
AcetarsolAn anti infective used to treat a wide variety of infections in the body.
AcetohexamideUsed in the management of diabetes mellitus type 2 (adult-onset).
AcetoxoloneNot Annotated
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
AcotiamideAcotiamide has been used in trials studying the treatment of Dyspepsia and Functional Dyspepsia.
Activated charcoalA gastric decontamination agent used in emergency clinical settings as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.
AdemetionineS-Adenosylmethionine (SAMe) is used as a drug in Europe for the treatment of depression, liver disorders, fibromyalgia, and osteoarthritis. It has also been introduced into the United States market as...
AdrenaloneNot Annotated
Agalsidase alfaA recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide.
Agalsidase betaA recombinant human alpha-galactosidase indicated to treat Fabry disease, a genetic deficiency in the enzyme leading to buildup of globotriaosylceramide.
AlbiglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
AlfacalcidolA vitamin D analogue used for the management of hypocalcemia, secondary hyperparathyroidism, and osteodystrophy in patients with chronic renal failure, as well as some types of rickets and osteomalacia.
Alginic acidIndicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress .
AlgluceraseA form of recombinant beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease.
Alglucosidase alfaAn acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency.
AlizaprideA dopamine antagonist used to prevent nausea and vomiting associated with medical procedures, surgeries, and cancer therapies.
AlmasilateAlmasilate is indicated for use as an antacid for the neutralization of excess stomach acid . It is subsequently also used for the symptomatic treatment of diseases where it is...
AlogliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
AloglutamolAloglutamol is an antacid salt of aluminium, gluconic acid, and tris. Proprietary names include Altris, Pyreses, Tasto and Sabro.
AlosetronA 5-HT3 antagonist used to treat diarrhea-predominant IBS.
Aluminium acetoacetateAluminium acetoacetate is an aluminum containing antacid.
Aluminium glycinateA medication indicated to treat heartburn, indigestion, acid reflux, ulcers, and gas.
Aluminium phosphateAn aluminum salt used clinically as an antacid and vaccine adjuvant.
Aluminum hydroxideAn antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
AlverineA smooth muscle relaxant used to relieve abdominal pain associated with gastrointestinal conditions like heartburn, flatulence, and Irritable Bowel Syndrome.
AlvimopanAn opioid antagonist used to reduce healing time of the upper and lower gastrointestinal tract following surgical procedures that involve bowel resection with primary anastomosis.
AmlexanoxUsed as a paste in the mouth to treat aphthous ulcers (canker sores).
AmoxicillinA penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
Anethole trithioneA medication used to treat dry mouth associated with medication or radiotherapy of the head and neck.
AprepitantA substance P/neurokinin 1 receptor antagonist used to treat nausea and vomiting caused by chemotherapy and surgery.
Arginine glutamateTwo amino acids indicated in the treatment of hyperammonemia and in combination for total parenteral nutrition.
Ascorbic acidA vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron.
Asfotase alfaAn enzyme replacement therapy used for the treatment of perinatal/infantile and juvenile onset hypophosphatasia (HPP).
Atidarsagene autotemcelA gene therapy comprising autologous CD34+ enriched stem cells encoding the human arylsulfatase A (ARSA) gene used to treat metachromatic leukodystrophy (MLD).
AtropineA muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs.
AttapulgiteA veterinary antidiarrheal agent used to treat non-infectious diarrhea in animals.
Avalglucosidase alfaA lysosomal glycogen-specific enzyme that is used to treat patients one year of age and older with late-onset Pompe disease, or lysosomal acid alpha-glucosidase (GAA) deficiency.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
BecaplerminA recombinant form of human platelet-derived growth factor used to treat ulcers due to diabetic neuropathy in the lower extremities when there is adequate blood supply to the area.
Beclomethasone dipropionateAn inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks.
BeinaglutideBeinaglutide is under investigation in clinical trial NCT03829891 (Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus).
BenfluorexBenfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier. The European Medicines Agency (EMA) recommended...
BenfotiamineA derivative of thiamine thought to be useful in the management of diabetic neuropathy, although evidence is lacking.
BenziloneNot Annotated
Benzoic acidAn antimicrobial food additive.
BenzoxoniumAn antiseptic indicated in skin disinfection and prevention of infections.
BenzydamineA locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy.
Beta caroteneA vitamin A precursor found in various nutritional supplements and health products.
BetaineA methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
BevoniumNot Annotated
BexagliflozinA sodium-glucose co-transporter 2 inhibitor used to improve glycemic control in patients with type 2 diabetes mellitus.
BiotinA B-complex vitamin found in many multivitamin products.
BisacodylA stimulant laxative used for the temporary relief of occasional constipation and cleansing of the colon as a preparation for colonoscopy in adults.
Bismuth subcitrate potassiumA colloid used for the treatment of peptic ulcer and gastro-esophageal reflux disease (GERD).
Bismuth subnitrateA medication used as an antacid.
BisoxatinFor use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon .
BromoprideA substituted benzamide, closely related to metoclopramide, used as an antiemetic.
BroxyquinolineNot Annotated
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
BuforminBuformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of...
ButylscopolamineAn antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain.
CalcifediolAn active metabolite of vitamin D used to treat hyperparathyroidism as well as to combat hypocalcemia in dialysis patients.
CalcitriolAn active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia.
CalciumA mineral found in over-the-counter supplements or prescription formulations used for the treatment of specific medical conditions related to calcium deficiency.
Calcium acetateA phosphate binder used in patients with end-stage renal disease (ESRD) to prevent elevated phosphate levels and resulting ectopic calcification and secondary hyperparathyroidism.
Calcium carbonateAn ionic compound used as a calcium supplement or antacid used for the symptomatic relief of heartburn, acid indigestion, and sour stomach.
Calcium chlorideAn ionic compound used for the treatment of hypocalcemia and hyperkalemia, and as an antidote to magnesium intoxication due to overdosage of magnesium sulfate.
Calcium citrateAn ingredient found in a variety of supplements and vitamins.
Calcium glubionate anhydrousA calcium salt indicated in the treatment of hypocalcemia, hyperkalemia, lead poisoning, and as an adjunct in the treatment of exudative skin conditions.
Calcium glucoheptonateA calcium supplement combined with calcium gluconate to treat hypocalcemia and maintain calcium levels.
Calcium gluconateAn ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning.
Calcium lactateAn ingredient found in a variety of nutritional products.
Calcium lactate gluconateA calcium salt indicated in the treatment of rickets, osteomalacia, and the treatment and prevention of calcium deficiency
Calcium levulinateThis new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and...
Calcium pangamateNot Annotated
Calcium PhosphateA compound used in supplements and antacids.
Calcium polycarbophilA bulk forming laxative used to treat constipation.
Calcium silicateNot Annotated
CamylofinNot Annotated
CanagliflozinA sodium-glucose co-transporter 2 (SGLT2) inhibitor used to manage hyperglycemia in type 2 diabetes mellitus (DM). Also used to reduce the risk of major cardiovascular events in patients with established cardiovascular disease and type 2 DM.
CarbenoxoloneA drug used to symptomatically treat lip sores and mouth ulcers.
CarbutamideNot Annotated
Carglumic acidAn analog of N-acetylglutamate (NAG) used for the treatment of acute and chronic hyperammonemia in patients with N-acetylglutamate synthase (NAGS) deficiency.
CaroverineA calcium channel blocker indicated in the treatment of smooth muscle spasms, alcohol and drug withdrawal, and tinnitus.
CasopitantInvestigated for use/treatment in urinary incontinence and adverse effects (chemotherapy).
Castor oilAn ingredient used in a variety of natural health products.
CathineUsed to decrease appetite.
Cerium oxalateNot Annotated
Cerliponase alfaAn enzyme replacement therapy used to treat neuronal ceroid lipofuscinosis type 2 (CLN2) disease, also known as tripeptidyl peptidase 1 (TPP1) deficiency.
CetylpyridiniumA compound used to reduce plaque and gingivitis, as well as whiten teeth.
Chenodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis.
ChlorbenzoxamineNot Annotated
ChlorhexidineAn antiseptic used to sterilize for surgeries and in healthcare practice, to reduce pocket depth in periodontitis, and to treat gingivitis.
ChlorobutanolNo approved therapeutic indications on its own.
ChlorpropamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
ChlortetracyclineThe first tetracycline antibiotic most commonly used for veterinary purposes.
CholecalciferolA form of Vitamin D used in the treatment of specific medical conditions such as refractory rickets, hypoparathyroidism, and familial hypophosphatemia, as well as osteoporosis and chronic kidney disease.
Cholic AcidA bile acid used for the treatment of bile acid synthesis disorders due to single enzyme defects and as an adjunctive treatment of peroxisomal disorders with disrupted liver function.
CilansetronFor the treatment of symptoms associated with irritable bowel syndrome.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
CimetropiumCimetropium is a semi-synthetic belladonna alkaloid and derivative of scopolamine. It is a potent antimuscarinic and an effective antispasmodic drug. It is also endowed of a direct myolitic action which...
CinitaprideA benzamide with gastroprokinetic and antiemetic properties typically used for the treatment of gastrointestinal motility disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, and delayed gastric emptying.
Cipaglucosidase alfaA recombinant human acid alpha-glucosidase used to treat late-onset Pompe disease in adults.
CisaprideA medication used to treat heartburn associated with GERD.
CitioloneNot Annotated
Citric acidAn anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.
ClarithromycinA macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
CleboprideA dopamine antagonist used to treat symptoms associated with functional gastrointestinal disorders. Clebopride may also be used to treat nausea and vomiting associated with chemotherapy.
ClidiniumA synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS.
ClobenzorexNot Annotated
ColistinA polymyxin antibiotic used to treat bacterial infections caused by susceptible Gram negative bacteria.
CrofelemerAn antidiarrheal agent used for the symptomatic relief of drug-induced non-infectious diarrhea in adult patients with HIV/AIDS receiving antiretroviral therapy.
Cromoglicic acidA medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions.
CyclobutyrolNot Annotated
CysteamineA cystine depleting agent used to treat the effects of cystinosis.
DantronA drug used to relieve acute and chronic inflammation of the oral cavity and oropharynx.
DapagliflozinA sodium-glucose cotransporter 2 inhibitor used in the management of type 2 diabetes mellitus.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DexfenfluramineFor the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet
DexlansoprazoleA proton pump inhibitor used to treat erosive esophagitis, heartburn, and gastroesophageal reflux disease (GERD).
DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DexrabeprazoleA proton pump inhibitor indicated in the treatment of gastroesophageal reflux disease and gastrointestinal ulcers.
DicyclomineAn antimuscarinic agent used to treat IBS.
DiethylpropionAn appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction.
DifemerineNot Annotated
DifenoxinAn antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
DihexyverineNot Annotated
DihydrotachysterolA synthetic analog of vitamin D that does not require renal activation like vitamin D2 or Vitamin D3.
DiisopromineNot Annotated
DimethylaminopropionylphenothiazineNot Annotated
DiphemanilUsed in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration).
DiphenoxylateAn antidiarrheal medication used with atropine to manage diarrhea.
DocusateA medication used to treat constipation associated with dry, hard stools, or opioid induced constipation.
DolasetronAn antinauseant and antiemetic used in chemotherapy and postoperatively.
DomiphenAnti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions.
DomperidoneA dopamine receptor antagonist used as a peristaltic stimulant and anti-emetic agent for dyspepsia, indigestion, epigastric pain, nausea, and vomiting.
DonislecelAn allogeneic pancreatic islets cellular therapy indicated for the treatment of type 1 diabetes
DorzagliatinDorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
DronabinolA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
DrotaverineA phosphodiesterase-4 inhibitor used to alleviate gastrointestinal and genitourinary smooth muscle spasms.
DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
Eladocagene exuparvovecA recombinant AAV2 vector containing the human aromatic L-amino acid decarboxylase (AADC) gene indicated for the treatment of AADC deficiency.
ElafibranorA peroxisome proliferator-activated receptor agonist used to treat primary biliary cholangitis in adults with intolerance of inadequate response to ursodeoxycholic acid.
EliglustatA glucosylceramide synthase used to treat type 1 Gaucher disease in patients who are CYP2D6 extensive, intermediate, or poor metabolizers.
Elivaldogene autotemcelA gene replacement therapy for treating early cerebral adrenoleukodystrophy comprising autologous hematopoietic stem cells transduced with a viral vector encoding ABCD1 complementary DNA for human adrenoleukodystrophy protein.
ElobixibatElobixibat has been used in trials studying the treatment and basic science of Dyslipidemia, Constipation, Chronic Constipation, Functional Constipation, and Chronic Idiopathic Constipation.
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
EluxadolineA mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
EmeproniumNot Annotated
Emetonium iodideNot Annotated
EmpagliflozinAn SGLT2 inhibitor used to manage type 2 diabetes mellitus.
EnavogliflozinEnavogliflozin is under investigation in clinical trial NCT06399835 (Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis).
EnprostilNot Annotated
EphedrineAn alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion.
EpomediolNot Annotated
ErgocalciferolA vitamin found in many supplement products.
ErtugliflozinAn SGLT2 inhibitor used to treat type 2 diabetes mellitus alone or in combination with other antidiabetic drugs.
Escherichia coliA probiotic indicated to treat urinary tract infections and irritable bowel syndrome.
EsomeprazoleA proton pump inhibitor used to treat GERD, reduce the risk of NSAID associated gastric ulcers, eradicate H. pylori, and to treat conditions causing gastric acid hypersecretion.
EthylestrenolAn anabolic steroid with some progestational activity and little androgenic effect. [PubChem]
EtilamfetamineEtilamfetamine is also known as N-ethylamphetamine and is in the Canadian Legislation - The Controlled Drugs and Substances Act, and is a Schedule 1 controlled drug. Like other amphetamines, this...
EvogliptinEvogliptin has been used in trials studying the treatment and screening of Osteoporosis, Renal Impairment, Type 2 Diabetes Mellitus, Diabetes Mellitis Type 2, and Diabetes Mellitus, Type 2.
ExenatideA GLP-1 agonist used in the management of type 2 diabetes mellitus.
FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
FenfluramineFenfluramine is a phenethylamine that is structurally similar to serotonin. Due to its ability to increase extracellular serotonin levels, modulate serotonergic and other neurologic receptors, and control neurotransmission, it is effective in treating pharmacoresistant seizures.
FenoverineA phenothiazine based anti-spasmodic agent indicated in the treatment of irritable bowel syndrome.
FenpipraneNot Annotated
FenpiveriniumAn anticholinergic agent indicated in the treatment of smooth muscle spasms.
FentoniumFentonium is an atropine derivative.
FexuprazanAbeprazan is under investigation in clinical trial NCT04341454 (Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Acute or Chronic Gastritis).
FidaxomicinA macrolide antibiotic used to treat diarrhea associated with Clostridium difficile infection.
FosdenopterinAn exogenous form of cyclic pyranopterin monophosphate (cPMP) used as a replacement substrate in patients with molybdenum cofactor deficiency (MoCD) type A.
GalsulfaseA recombinant human enzyme used as replacement enzyme therapy for the treatment of of adults and children with Mucopolysaccharidosis VI, a rare genetic disorder caused by a deficiency of a lysosomal enzyme.
GavorestatGavorestat is under investigation in clinical trial NCT04902781 (Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia).
GefarnateGefarnate has been investigated for the treatment and prevention of Stomach Ulcer, Duodenal Ulcer, and Cardio-cerebrovascular Disease.
GemigliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
GivosiranA 5-aminolevulinic acid synthase-directed small interfering RNA (siRNA) used in the prophylaxis of acute hepatic porphyria.
GlibornurideGlibornuride is a sulfonylurea-type anti-diabetic drug.
GliclazideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
GlimepirideA sulfonylurea drug used to treat type 2 diabetes mellitus.
GlipizideA sulfonylurea medication used in Type 2 Diabetes to sensitize pancreatic beta cells and stimulate insulin release.
GliquidoneA sulfonylurea drug used in the management of diabetes mellitus type 2.
GlisoxepideFor the treatment of diabetes mellitus type 2.
Glutamic acidAn amino acid commonly found as a component in total parenteral nutrition.
GlyburideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
Glycerol phenylbutyrateA nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.
GlycopyrroniumAn anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia.
Glycyrrhizic acidGlycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to...
GlymidineGlycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.
GranisetronA 5HT3 antagonist used to treat nausea and vomiting in cancer therapy and postoperatively.
Guar gumNot Annotated
HexetidineAn topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.
HexocycliumThe World Health Organization classifies hexocyclium as a drug for functional gastrointestinal disorders . Like other anti-muscarinic agents, hexocyclium was likely used to treat peptic ulcers or diarrhea.
Homatropine methylbromideA muscarinic receptor antagonist used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
Hydrochloric acidA strong acid used to adjust the pH of injections and ophthalmic solutions.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
Hydrogen peroxideA compound used as a disinfectant and sterilizer.
HydrotalciteAn antacid indicated in the treatment of heartburn and excess gastric acid.
HymecromoneA coumarin derivative that lacks anticoagulant properties but possesses choleretic and biliary antispasmodic activity.
HyoscyamineAn anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis.
IdanpramineNot Annotated
IdursulfaseA purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients.
Idursulfase betaIdursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
IlaprazoleIlaprazole has been investigated in Helicobacter Infections.
ImegliminImeglimin has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
ImigluceraseA form of recombinant human beta-glucocerebrosidase enzyme used to replace the deficient endogenous enzyme in the treatment of Gaucher disease.
InositolAn ingredient found in a variety of nutritional products.
Insulin aspartA rapid-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus.
Insulin beefInsulin beef has been discontinued in the US and Canada since 2017.
Insulin degludecA long acting insulin used to treat hyperglycemia caused by type 1 and 2 diabetes mellitus.
Insulin detemirA long-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus.
Insulin glargineA modified form of long-acting or basal insulin used to control hyperglycemia in diabetes mellitus.
Insulin glulisineA short-acting form of insulin used for glycemic control in type 1 and type 2 diabetes mellitus.
Insulin humanA recombinant form of human insulin used to control hyperglycemia in diabetes mellitus.
Insulin icodecAn ultra long-acting basal insulin analogue for once-weekly injection in patients with diabetes mellitus.
Insulin lisproA modified form of fast-acting insulin used to control hyperglycemia in diabetes mellitus.
Insulin porkA purified form of porcine insulin used to control hyperglycemia in diabetes mellitus.
IpragliflozinIpragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
IronAn essential element commonly used for the treatment of patients with documented iron deficiency.
IrsogladineIrsogladine is under investigation in clinical trial NCT02581696 (The Drug-drug Interaction and Safety of Lafutidine and Irsogladine Maleate in Healthy Adult Volunteers).
IsomethepteneA sympathomimetic used to relieve painful spasms in combination with other agents such as caffeine and metamizole.
IsopropamideA long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions.
ItoprideAn acetylcholine esterase inhibitor and dopamine D2 receptor antagonist used to treat symptoms of functional dyspepsia such as nausea and vomiting.
KanamycinAn aminoglycoside antibiotic agent used in the treatment of various infections caused by susceptible bacteria.
KaolinA natural ingredient used for the short-term symptomatic treatment of various conditions including diarrhea, skin dryness, and minor skin bleeding.
Karaya gumAn extract from Karaya gum used in allergy testing.
L-GlutamineAn amino acid commonly found as a component in total parenteral nutrition.
LactitolAn orally administered osmotic laxative used to treat chronic idiopathic constipation.
LactuloseA disaccharide derivative of lactose used to treat constipation and portal systemic encephalopathy.
LafutidineLafutidine has been investigated in Peptic Ulcer, Community-acquired Pneumonia, and Gastroesophageal Reflux Disease (GERD).
LansoprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
LaronidaseA form of recombinant human alpha-L-iduronidase used to treat Hurler and Hurler-Scheie forms of mucopolysaccharidosis, a genetic deficiency of alpha-L-iduronidase.
LeriglitazoneLeriglitazone is under investigation in clinical trial NCT03917225 (A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients).
LevocarnitineA quaternary ammonium compound used to treat carnitine deficiency or to stimulate gastric and pancreatic secretions in hyperlipoproteinemia.
LevofloxacinA fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria of the upper respiratory tract, skin and skin structures, urinary tract, and prostate, as well as for post-exposure treatment of inhaled anthrax and the plague.
LinaclotideA guanylate cyclase-C agonist used to treat different types of constipation, such as irritable bowel syndrome-related constipation, idiopathic constipation, and functional constipation.
LinagliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to manage hyperglycemia in patients with type 2 diabetes mellitus.
Lipoic acidFor nutritional supplementation, also for treating dietary shortage or imbalance.
LiraglutideA GLP-1 analog used in the management of type 2 diabetes mellitus, prevention of cardiovascular complications associated with diabetes, and obesity.
LixisenatideA GLP-1 receptor agonist used for the management of type 2 diabetes mellitus.
LobeglitazoneLobeglitazone was approved by the Ministry of Food and Drug Safety (South Korea) in 2013, and is being monitored by postmarketing surveillance until 2019. Lobeglitazone is not approved for use...
LonafarnibA potent farnesyl transferase inhibitor used to reduce mortality associated with Hutchinson-Gilford progeria syndrome (HGPS) and other progeroid laminopathies.
LoperamideA long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
Loperamide oxideNot Annotated
LorcaserinA serotonin 2C receptor agonist used in conjunction with physical activity and calorie restriction for weight loss in obese patients with a body mass index (BMI) of 30 and above, and in overweight patients with weight-related comorbidities.
LubiprostoneA prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use.
LumasiranLumasiran is an interfering RNA that silences hydroxyacid oxidase 1 for the treatment of primary hypoxaluria type 1.
LuseogliflozinAn SGLT2 inhibitor used to manage type 2 diabetes mellitus.
MagaldrateAn antacid used to treat various conditions in the GI tract, such as esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux.
Magnesium aspartateMagnesium aspartate is a magnesium salt of aspartic acid that is commonly used as a mineral supplement. It displays high oral bioavailability and water solubiltiy compared to other magnesium salts...
Magnesium carbonateAn antacid used for symptomatic relief of heartburn, indigestion, and upset stomach.
Magnesium chlorideAn ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies.
Magnesium citrateA laxative used in bowel preparation for colonoscopy or as a magnesium supplement.
Magnesium gluconateA mineral supplement used to treat or prevent hypomagnesemia.
Magnesium hydroxideAn inorganic compound used as a laxative and antacid.
Magnesium lactateNot Available
Magnesium levulinateA supplement to treat magnesium deficiency.
Magnesium orotateMagnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat...
Magnesium oxideA compound commonly used as a laxative for the symptomatic relief of acid indigestion and upset stomach, and in health supplements for cardiovascular and neuromuscular health.
Magnesium peroxideNot Annotated
Magnesium silicateMagnesium silicate is used to absorb moisture, prevent caking, and to improve the feel of a product. In the pharmaceutical companies, it is used as a dietary supplement, as part...
Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis.
MaralixibatAn ileal bile acid transporter inhibitor indicated to treat cholestatic pruritus in patients with Alagille syndrome.
MazindolA sympathomimetic used to treat obesity in combination with lifestyle modifications.
MebeverineAn antispasmodic used for the symptomatic treatment of stomach pain and spasms associated with irritable bowel syndrome and other gastrointestinal illnesses.
MefenorexNot Annotated
MepartricinA medication indicated in the treatment of benign prostatic hyperplasia, vaginal candidiasis, or trichomoniasis.
MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
MetadoxineA medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy.
MetahexamideNot Annotated
MetandienoneAn anabolic steroid indicated for appetite stimulation in patients with anorexia.
MetenoloneAn anabolic steroid indicated in the treatment and prevention of muscle wasting due to diseases, drug treatments, or other catabolic processes.
MetforminA biguanide antihyperglycemic used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus. It is also used off-label for insulin resistance in polycystic ovary syndrome (PCOS).
MethanthelineFor the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children.
MethscopolamineMethscopolamine is a quaternary ammonium derivative of scopolamine and antagonist at muscarininc (mACh) receptors. Methscopolamine bromide is the most common form of the active ingredient in oral pharmaceutical products. The...
MethylatropineNot Annotated
MethylcelluloseA compound used as a bulk forming laxative and is not an approved medication.
Methylmethionine chlorideMethylmethionine chloride may be useful in helping the healing of gastric ulcers. In Japan, it is used as an over the counter product for gastrointestinal health support. It is also...
MethylnaltrexoneA μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
MetopimazineNot Annotated
MetreleptinA leptin analogue used as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients various forms of lipodystrophy.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
MigalastatAn alpha-galactosidase A chaperone used for the treatment of Fabry disease in patients with an amenable galactosidase alpha gene (GLA) variant.
MiglitolAn oral alpha-glucosidase inhibitor used to improve glycemic control by delaying the digestion of carbohydrates.
MiglustatA glucosylceramide synthase inhibitor used for the management of mild to moderate type I Gaucher disease for patients who are not candidates for whole enzyme replacement.
Mineral oilMineral oil is not considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indication. It is typically present in topical formulations as an emollient and occlusive...
MinocyclineA tetracycline analog used to treat a wide variety of infections in the body.
MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers and to terminate pregnancies.
MitiglinideFor the treatment of type 2 diabetes.
MontmorilloniteA purified clay indicated in the treatment of intestinal pain and diarrhea.
MosaprideA prokinetic 5-HT4 receptor agonist used to stimulate gastric motility.
MoxaverineMoxaverine has been investigated for the treatment of Retina, Ocular Physiology, and Regional Blood Flow.
N-methylnicotinamideN-methylnicotinamide is an experimental drug with no approved indication.
NabiloneA synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy.
NaldemedineAn opioid antagonist used to to treat opioid-induced constipation.
NaloxegolA peripherally-selective opioid antagonist used to treat opioid-induced constipation (OIC) in adult patients with chronic non-cancer pain.
NaloxoneAn opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection.
NaltrexoneA narcotic antagonist used in opioid overdose.
NandroloneAn anabolic steroid indicated to increase bone density and muscle mass in patients with osteoporosis.
NatamycinA macrolide antifungal used to treat fungal infections of the eye.
NateglinideA meglitinide used to treat non insulin dependent diabetes mellitus.
NedosiranAn antisense oligonucleotide used to treat primary hyperoxaluria type 1 in adults and high oxalate levels in children
NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
NicofetamideNot Annotated
NicotinamideAn ingredient found in a variety of cosmetic products.
NifuroxazideAn antibiotic indicated in the treatment of susceptible gastrointestinal infections.
NifurzideNot Annotated
NiperotidineNot Annotated
NitisinoneA hydroxyphenylpyruvate dioxygenase inhibitor used as an adjunct to dietary restrictions for the treatment of hereditary tyrosinemia type 1 (HT-1) and Alkaptonuria, which cause intolerance to tyrosine containing foods.
NizatidineAn H2 receptor antagonist used to treat GERD and a variety of ulcers.
NorethandroloneNorethandrolone is under investigation in clinical trial NCT00700544 (Treatment Outcome in Elderly Patients).
NystatinA polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
Obeticholic acidA bile acid analog and farnesoid X receptor agonist used to treat primary biliary cholangitis in adult patients with inadequate clinical response or intolerance to UDCA.
OctenidineAn antiseptic agent used topically, on mucous membranes, and prior to surgery.
OdevixibatAn ileal sodium/bile acid cotransporter inhibitor indicated in the treatment of pruritus in patients with progressive familial intrahepatic cholestasis.
OlaflurA fluoride treatment for patients at risk of dental caries, sensitive teeth, or enamel decalcification.
Olipudase alfaA recombinant human acid sphingomyelinase used to treat Acid Sphingomyelinase Deficiency (ASMD) in children and adults.
OlsalazineAn anti-inflammatory aminosalicylate used in the treatment of inflammatory bowel disease and ulcerative colitis.
Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
OpiumA medication used to treat moderate to severe pain.
OrlistatA reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.
OrnithineAn amino acid commonly found as a component in total parenteral nutrition.
OtiloniumA spasmolytic medication used to treat irritable bowel syndrome (IBS).
Oxabolone cipionateUsed as a performance enhancing drug illicitly in athletes.
OxandroloneAn androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis.
OxymetholoneAn anabolic steroid used for the treatment of types of anemia, such as acquired aplastic anemia, congenital aplastic anemia, myelofibrosis, and the hypoplastic anemias.
OxyphencyclimineA drug used to treat smooth muscle spasticity.
OxyphenisatinA laxative that undergoes enterohepatic circulation. It may cause jaundice.
OxyphenoniumFor the treatment of visceral spasms
OxyquinolineA medication used in combination with other medications to restore vaginal pH.
OxytetracyclineA tetracycline antibiotic used to treat a wide variety of susceptible bacterial infections.
Pabinafusp alfaPabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).
PalonosetronA serotonin antagonist used in the prophylaxis or management of vomiting that results from emetogenic chemotherapy, and for the management of postoperative nausea and vomiting.
PancrelipaseA purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis.
PantethineA naturally occurring compound derived from panthothenic acid. It acts as an intermediate in endogenous coenzyme A synthesis and is used as a dietary supplement to treat hypertriglyceridemia.
PantoprazoleA proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid.
Pantothenic acidA vitamin B5 found in various nutritional supplements.
PapaverineAn alkaloid used to treat many types of smooth muscle spasms such as "vascular spasms" associated with acute myocardial infarction and angina pectoris, as well as "visceral spasms".
ParomomycinAn aminoglycoside antibiotic used in the treatment of acute and chronic intestinal amebiasis, and as an adjunct for the management of hepatic coma.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
Pegunigalsidase alfaA recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease.
PegvaliaseAn enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment.
PegzilarginaseA recombinant human arginase 1 enzyme replacement therapy used for the chronic management of hyperargininemia in patients with arginase 1 deficiency (ARG1-D).
PentaerithritylNot Annotated
PenthienateNot Annotated
Peppermint oilAn ingredient used in a variety of natural health products and is not an approved medication.
PepsinA protease indicated in the treatment of digestive disorders.
Perboric acidIn the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid...
PhenforminFor the reatment of type II diabetes mellitus.
PhenolphthaleinA drug used for symptomatic relief of constipation and bowel cleansing prior to medical procedures.
PhentermineA sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity.
Phenylacetic acidAn agent used as an adjunct to treat acute hyperammonemia and associated encephalopathy in adult and pediatric patients with deficiencies in enzymes of the urea cycle.
Phenylbutyric acidAn agent indicated for the adjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in specific enzymes, including the neonatal-onset deficiency and late-onset disease with a history of hyperammonemic encephalopathy.
PhloroglucinolA spasmolytic agent to treat colic, as well as spastic pain of the digestive and biliary tracts.
PhthalylsulfathiazoleA sulfonamide antibacterial indicated in the treatment of gastrointestinal infections.
Picosulfuric acidA stimulant laxative used for cleansing of the colon as a preparation for colonoscopy in adults.
Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
PinaveriumA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
PioglitazoneA thiazolidinedione used adjunctively with diet and exercise to normalize glycemic levels in adults with type 2 diabetes mellitus.
PipenzolateAn antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia.
PiperidolateNot Annotated
PiprozolinNot Annotated
PirenzepineAn antimuscarinic agent used to treat peptic ulcers, gastric ulcers, and duodenal ulcers.
PitofenoneA medication used in the treatment of spastic pain caused by menstrual cramps, the digestive system, and the urinary tract.
Plantago ovata seedA plant extract indicated in the treatment of occasional constipation.
PlecanatideA laxative used to treat chronic idiopathic constipation and IBS with constipation.
PoldineNot Annotated
Polyethylene glycolA laxative used to treat constipation and used for bowel preparation before colonoscopies and other procedures.
Polymyxin BA polymyxin antibiotic used to treat a wide variety of infections in the body.
PotassiumA medication used to treat hypokalemic conditions and to clear the colon prior to colonoscopy.
Potassium bicarbonateAn ingredient used as an antacid or to treat hypokalemia.
Potassium chlorideA potassium salt used to treat hypokalemia.
Potassium citrateAn agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones.
Potassium gluconateA potassium supplement indicated in the treatment and prevention of hypokalemia.
PramlintideAn amylin analog used for the management of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy.
PrasteroneA steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy.
PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
PrifiniumPrifinium is an antimuscarinic agent with antispasmodic and antiemetic properties. It may be useful for the treatment of irritable bowel syndrome .
ProglumideNot Annotated
PropanthelineAn antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder.
ProxazoleNot Annotated
PrucaloprideA 5-HT4 receptor agonist indicated to treat adults with chronic idiopathic constipation.
Pyridoxal phosphateA vitamin available in many formulations to correct vitamin B6 deficiency.
PyridoxineA vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy.
QuinboloneNot Annotated
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
RacecadotrilAn anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea.
RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
RebamipideA gastroprotective agent used in combination with other similar therapies (e.g. proton pump inhibitors) to treat gastritis and protect the gastric mucosa.
RepaglinideA antihyperglycemic used to improve glycemic control in diabetes.
RiboflavinA vitamin used to correct vitamin B2 deficiency.
RifabutinAn antibiotic used to treat mycobacterium avium complex disease in patients with HIV.
RifamycinAn antibacterial used to treat traveler's diarrhea.
RifaximinA rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
RimonabantFor use in conjunction with diet and exercise for patients with a body mass index greater than 30 kg/m2, or patients wih a BMI greater than 27 kg/m2 with associated...
RociverineAn antispasmodic indicated in the treatment of urinary, gastrointestinal, and biliary tract spasms.
RolapitantA neurokinin-1 (NK-1) receptor antagonist used in combination with other antiemetics for the prevention of delayed nausea and vomiting associated with emetogenic chemotherapy.
RosiglitazoneA thiazolidinedione indicated as an adjunct to diet and exercise to maintain glycemic control in type 2 diabetes.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Roxatidine acetateFor the treatment of disorders of the upper gastro-intestinal region that are due to an excess of hydrochloric acid in the gastric juice, i.e. duodenal ulcers, benign gastric ulcers. Also...
SacrosidaseAn enzyme replacement therapy used for the treatment of congenital sucrase-isomaltase deficiency (CSID).
SapropterinA cofactor used as an adjunct to phenylalanine restriction in the treatment of phenylketonuria (PKU).
SaxagliptinAn DPP-4 inhibitor used for the management of type 2 diabetes mellitus.
ScopolamineA belladonna alkaloid with anticholinergic effects indicated for the treatment of nausea and vomiting associated with motion sickness and postoperative nausea and vomiting (PONV).
Sebelipase alfaA recombinant lysosomal acid lipase used to treat lysosomal acid lipase deficiency.
SeladelparA PPAR-delta agonist used to treat primary biliary cholangitis alone or in combination with ursodeoxycholic acid in adults.
Selenic acidAn ingredient found in a variety of supplements and vitamins.
Selenious acidAn ingredient found in supplements, vitamins, parenteral nutrition, and dandruff shampoo.
SeleniumAn ingredient found in a variety of supplements and vitamins.
SemaglutideA glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus, treat obesity, and reduce the risk of major adverse cardiovascular events in selected adults.
SennosidesA laxative used to treat constipation.
SetmelanotideA drug indicated to treat obesity caused by genetic POMC, PCSK1, or LEPR deficiencies or Bardet-Biedl syndrome.
SibutramineA norepinephrine, serotonin and dopamine reuptake inhibitor indicated to assist with weight loss in obesity.
SilibininA flavonolignan with hepatoprotective effects used to treat toxic liver damage and as an adjunct in the management of chronic conditions such as cirrhosis and hepatitis.
SitagliptinAn oral dipeptidyl peptidase-4 (DPP-4) inhibitor used for the management of type 2 diabetes mellitus.
Sodium chlorideAn ingredient found in a variety of nutritional products as a source of electrolytes and water.
Sodium fluorideAn ingredient of various dental preparations used to support tooth mineralization and the prevention of dental caries.
Sodium fluorophosphateA fluoride anticaries agent used to prevent and treat dental cavities.
Sodium lauryl sulfoacetateA laxative indicated in the treatment of constipation and bowel preparation for rectal endoscopy.
Sodium phosphate, monobasicA source of phosphorus used prevent or correct hypophosphatemia in patients with restricted or no oral intake.
Sodium sulfateAn agent used for bowel cleansing prior to colonoscopy or barium enema X-ray examination.
Sodium tartrateIt acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to...
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
SotagliflozinAn orally administered dual SGLT1/2 inhibitor used alongside insulin to improve glycemic control in patients with type 1 diabetes mellitus.
Stannous fluorideA medication used to treat dental hypersensitivity, produce enamel, prevent gingivitis and cavities, and prevent periodontal infections.
StanoloneA potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure...
StanozololAn anabolic steroid used to manage hereditary angioedema.
StreptomycinAn aminoglycoside antibiotic indicated to treat multi-drug resistant mycobacterium tuberculosis and various non-tuberculosis infections.
SuccinylsulfathiazoleNot Annotated
SucralfateA gastro-duodenal protective agent used in the treatment of gastric and duodenal ulcers and to prevent duodenal ulcer recurrence.
SulbutiamineA thiamine derivative indicated in the treatment of asthenia.
SulfaguanidineSulfaguanidine is a sulfonamide antibiotic with antimicrobial and antibacterial activities.
SulfasalazineA salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis.
SulglicotideNot Annotated
Taliglucerase alfaA hydrolytic lysosomal glucocerebroside specific enzyme, used for long term enzyme replacement therapy in patients with Type 1 Gaucher disease.
Tauroursodeoxycholic acidThe taurine conjugate of ursodeoxycholic acid with antiapoptotic and ER stress response dampening effects used in some countries to treat gallstones. It is also being investigated for a wide variety of other conditions.
TeduglutideA glucagon-like peptide-2 (GLP-2) analog used to treat patients with Short Bowel Syndrome (SBS) who require parenteral nutritional support.
TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
TegoprazanTegoprazan (also known as CJ-12420) is a novel therapeutic developed by CJ Healthcare Corp for treating acid-related gastrointestinal diseases. This drug is a potent and high-selective potassium-competitive acid blocker (P-CAB)...
TelotristatA tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
TenapanorAn NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic kidney disease,
TeneligliptinTeneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus.
TeplizumabA CD3-directed monoclonal antibody indicated to delay the onset of Stage 3 type 1 diabetes in patients with Stage 2 type 1 diabetes.
TeprenoneA medication indicated in the treatment of acute gastroenteritis, exacerbations of gastric inflammation, and gastric ulcers.
TetracyclineAn antibiotic used to treat a wide variety of susceptible infections.
ThiamineA vitamin used to correct vitamin B1 deficiency.
Tibezonium iodideNot Annotated
Tidiacic arginineNot Annotated
Tiemonium iodideNot Annotated
TilactaseA beta-D-galactosidase use to treat lactose intolerance.
TimepidiumNot Annotated
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
TiropramideA medication indicated in the treatment of spastic pain of the gastrointestinal system.
TirzepatideA dual GIP and GLP-1 receptor agonist used for the treatment of type II diabetes in adults as an adjunct to diet and exercise.
TixocortolA corticosteroid used for the symptomatic treatment of rhinitis, pharyngitis, and ulcerative colitis.
TocofersolanA derivative of alpha tocopherol used to treat vitamin E deficiencies.
TocopherolTocopherol can be used as a dietary supplement for patients with a deficit of vitamin E; this is mainly prescribed in the alpha form. Vitamin E deficiency is rare, and...
TolazamideA sulfonylurea used in the treatment of non insulin dependent diabetes mellitus.
TolbutamideA sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus.
TolrestatFor the pharmacological control of certain diabetic complications.
TopiramateAn anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
TrepibutoneNot Annotated
TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
TridihexethylUsed as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus
TriethylenetetramineA copper chelating agent used for the management of Wilson's disease in cases where penicillamine therapy is clinically inappropriate.
TriheptanoinTriheptanoin is a medium chain triglyceride indicated to provide calories and fatty acids to treat long chain fatty acid oxidation disorders.
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
TrimethyldiphenylpropylamineNot Annotated
TroglitazoneFor the treatment of Type II diabetes mellitus. It is used alone or in combination with a sulfonylurea, metformin, or insulin as an adjunct to diet and exercise.
TropisetronA 5HT-3 receptor antagonist used as an antiemetic in the treatment of chemotherapy-induced nausea and vomiting.
TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
TroxipideNot Annotated
Uridine triacetateA pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine.
Ursodeoxycholic acidA bile acid used for the treatment of primary biliary cirrhosis (PBC).
ValethamateAn anticholinergic medication used to symptomatically manage conditions involving smooth muscle spasms including spastic constipation, dysmenorrhea, and gastrointestinal tract cramping.
VancomycinA glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.
Velaglucerase alfaAn enzyme replacement therapy used for the long-term treatment of for pediatric and adult patients with type 1 Gaucher disease.
Velmanase alfaA recombinant human lysosomal alpha-mannosidase used to treat non-neurological symptoms of mild to moderate alpha-mannosidosis.
Vestronidase alfaA recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII.
VildagliptinA once-daily dipeptidyl peptidase 4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus.
Vitamin AA vitamin important for retinal function that is used clinically to correct vitamin A deficiency.
VogliboseAn alpha-glucosidase inhibitor indicated in the management of postprandial blood glucose in patients with type II diabetes.
VonoprazanA potassium-competitive acid blocker used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication.
YeastAn extract from Yeast used in allergy testing.
Zinc acetateA medication used to treat zinc deficiency.
Zinc gluconateAn ingredient found in a variety of supplements and vitamins.
Zinc sulfateA drug used to replenish low levels of zinc or prevent zinc deficiency, or to test for zinc deficiency.
ZolimidineNot Annotated