Candidiasis (DBCOND0020645)

Identifiers

Synonyms
Candidiasis infection / Candida Infections / Candida / Candida Infection / Candidal infection / Candidiasis, unspecified / Candidal infection NOS / Monilial infection / Moniliasis NOS / Monilia NOS / Moniliasis / Candida NOS / Candidiasis of unspecified site / Candidiasis NOS / Candidiasis (disorder) / Candida (organism) / Candidal stomatitis / Oral muguet / Candida of mouth / Thrush oral / Candida stomatitis / Oral candida / Thrush / Stomatitis monilial / Thrush NOS / Oral thrush / Oral candidiasis / Candidiasis of mouth (disorder) / Candidiasis, Oral / Candidiasis of mouth / Oral moniliasis / Moniliasis oral

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Anidulafungin
An antifungal used in the treatment of several types of candida infections.
Caspofungin
An echinocandin used to treat a variety of fungal infections.
Clotrimazole
A topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
Fluconazole
A triazole antifungal used to treat various fungal infections including candidiasis.
Flucytosine
An antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
Micafungin
An antifungal agent used for the treatment of candidemia, acute disseminated candidiasis, and certain other invasive Candida infections, and for the prophylaxis of Candida infections during stem cell transplantation.
Miconazole
An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
Nystatin
A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
Posaconazole
A triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Secnidazole
A nitroimidazole antibiotic used to treat bacterial vaginosis.
Voriconazole
A triazole compound used to treat fungal infections.
Zinc
An essential element commonly used for the treatment of patients with documented zinc deficiency.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02631954
Phase I Clinical Trial for Comparison of Pharmacokinetic Characteristics of Vorico Injection 200mg(Voriconazole) and Vfend® IV 200mg for Single Dose Crossover Intravenous Infusion in Healthy Volunteerstreatment1completed
NCT02413892
Impact of a Loading Dose of Caspofungin in Invasive Candidiasis in ICU PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00109525
Early Diagnosis of Candidiasis in Premature InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT00058682
Anidulafungin Versus Fluconazole in the Treatment of CandidemiaNo drug interventionstreatment3completed
NCT00697944
Ambisome® Preemptive Treatment of Multiple Candida Colonization in Sepsis PatientsNo drug interventionsprevention4unknown_status
NCT00818584
An Open-Label Study of the Safety and Pharmacokinetics of Repeated-Dose Micafungin in NeonatesNo drug interventionsNot Available1completed
NCT01077336
Clinical Outcomes in Candidemia Patients Based on in Vitro SusceptibilityNo drug interventionsNot AvailableNot Availablecompleted
NCT04874441
Candida PCR Diagnosis Strategy in Patients From Intensive Care UnitsNo drug interventionsdiagnosticNot Availablerecruiting
NCT05614726
A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized StudyNo drug interventionsbasic_scienceNot Availablecompleted
NCT03212729
Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological StudyNo drug interventionstreatmentNot Availablecompleted
NCT00366223
Changing Patterns of Candida Infections in Urban Medical CentersNo drug interventionsNot AvailableNot Availablecompleted
NCT03203551
Clinical and Laboratorial Evaluation of the Desinfection Solutions in Candida Species From Total Prostheses and Palate of Total Edentulous.No drug interventionspreventionNot Availablecompleted
NCT05720728
Research of New Serological Markers for the Diagnosis and Monitoring of Candidaemia in Hospitalized PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03630770
Effect of Medium Chain Triglyceride Intake on Colonization of Preterm Infants With Candidaprevention1completed
NCT04935463
Mucormycosis in COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT01495039
Antifungal Prophylaxis in Intensive Care Unit (ICU) Patientsprevention4completed
NCT03666195
The Anti-microbial Effect of Titanium Dioxide Nano Particles in Complete Dentures Made for Edentulous PatientsNo drug interventionspreventionNot Availableunknown_status
NCT01743690
The Use of Probiotics in Patients With Symptomatic Oral Lichen PlanusNo drug interventionspreventionNot Availablecompleted
NCT04148287
An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida AurisNo drug interventionstreatment2completed
NCT05761197
Oropharyngeal Candidiasis (OPC) and S-ECCNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05225493
HIV Indicator Diseases in Hospital and Primary CareNo drug interventionsNot AvailableNot Availableunknown_status
NCT03140748
Kinetics of Serum β-D-glucan During Peritonitis With Candida in ResuscitationNo drug interventionsscreeningNot Availablecompleted
NCT05908682
Safety of Pregnant Subjects Exposed to Ibrexafungerp Including Infant OutcomesNo drug interventionsNot AvailableNot Availablerecruiting
NCT03641131
Ampholipad Real-World Data in TaiwanNo drug interventionsNot AvailableNot Availablecompleted
NCT06146504
Clinical Study to Evaluate the Efficacy of an Anti-Fungal SupplementNo drug interventionsotherNot Availablecompleted
NCT01102387
Efficacy and Safety of LAS41003 in the Treatment of Intertriginous Candida Infectionstreatment2completed
NCT04502277
Bioavailability of Flucanazoleother0unknown_status
NCT00692783
Incidence of Oral Candidiasis, Prevalence of C. Dubliniensis in HIV Patients and In-vitro Azole SusceptibilityNo drug interventionsNot AvailableNot Availableterminated
NCT00163111
A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood.No drug interventionstreatment3completed
NCT00001107
Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplantsprevention4completed
NCT01447407
Effect of Adjuvant & Route of Administration on Safety & Immunogenicity of NDV-3 VaccineNo drug interventionsprevention1completed
NCT00889356
Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasistreatment3unknown_status
NCT02145832
Fluconazole Versus Micafungin in Neonates With Candidiasistreatment2 / 3unknown_status
NCT02641717
Validity of Patient-Collected Wet MountsNo drug interventionsdiagnosticNot Availablecompleted
NCT00739934
Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infectiontreatment2completed
NCT00082524
Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043)No drug interventionstreatment2completed
NCT00612963
Novel Rinse to Treat in Oral Candidiasis in Cancer PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00734539
Fluconazole Prophylaxis for the Prevention of Candidiasis in Infants Less Than 750 Grams Birthweightprevention3completed
NCT01273922
Safety and Immunogenicity Study of a Recombinant Protein Vaccine (NDV-3) Against S.Aureus and CandidaNo drug interventionsprevention1completed
NCT06472765
Vaginal Ecosystem and Network in the United States StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00797420
Pharmacokinetics (PK) Study of a Fluconazole Loading Dose in Infants and Toddlerstreatment1completed
NCT01919931
Immunological Interaction Between the Host and Candida Albicans BiofilmNo drug interventionsNot AvailableNot Availablecompleted
NCT00313131
Study of the Management of Vaginal Discharge in West African Using Single Dose TreatmentsNo drug interventionstreatment3completed
NCT03828773
PTX3-targeted Antifungal ProphylaxispreventionNot Availablerecruiting
NCT04122560
Fluconazole Pharmacokinetics, Including Bioavailability, in Obese Subjects After an Intravenous and Oral Administrationtreatment4completed
NCT00105144
Study of Micafungin in Patients With Invasive Candidiasis or CandidemiaNo drug interventionstreatment3completed
NCT00805740
An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To CandidaNo drug interventionstreatment3terminated
NCT00041704
The Safety and Efficacy of Intravenous Anidulafungin as a Treatment for Azole-Refractory Mucosal Candidiasis (FRMC)treatment2completed
NCT00784368
A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal InfectionNo drug interventionstreatment3completed
NCT00056368
The Safety and Efficacy of Anidulafungin Versus Comparator in Patients With Candidemia and Invasive CandidiasisNo drug interventionstreatment3completed
NCT00005912
Voriconazole to Prevent Systemic Fungal Infections in Childrentreatment1completed
NCT01230814
Topical Metronidazole and Miconazole Co-formulated Vaginal Suppositories for Preventing Vaginal Infections in HIV-seronegative WomenNo drug interventionsprevention2completed
NCT02493738
A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male VolunteersNo drug interventionsNot Available1completed
NCT00002038
Non-Comparative Study of Fluconazole in Patients With Serious Mycoses and Who Cannot Be Treated With Conventional Antifungal TherapytreatmentNot Availablecompleted
NCT00083343
Caspofungin for the Treatment of Non-blood Candida Infections (0991-045)No drug interventionstreatment2completed
NCT00138502
Funguria in Hospitalized PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00036179
Study of FK463 in the Treatment of Candidemia or Invasive Candidiasistreatment2completed
NCT01253954
A Multicenter Observational Study of Invasive Candida Infections Among ICU Patients in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT00806351
An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune SystemNo drug interventionstreatment3terminated
NCT01202253
Early Clinical Experience With Anidulafungin In Patients With Liver Disease In The United KingdomNo drug interventionsNot AvailableNot Availablecompleted
NCT02860845
Use of Boric Acid in Combination With Probiotics for the Treatment of Vaginal InfectionsNo drug interventionstreatment4completed
NCT01322698
Staging Candidiasis in ICU PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00496197
Study Will Evaluate The Safety And Efficacy Of Anidulafungin In Patients With Candidemia Or Invasive CandidiasisNo drug interventionstreatment4completed
NCT05235711
The Role Of Interferon-gamma In Immune Responses To Invasive CandidiasisNo drug interventionsNot AvailableNot Availablerecruiting
NCT01982071
A Study to Evaluate the Efficacy and Safety of Micafungin Against Invasive Candidiasis or CandidemiaNo drug interventionstreatment4terminated
NCT00106288
Micafungin Versus AmBisome in Invasive Candidiasis and CandidemiaNo drug interventionstreatment3completed
NCT00000788
A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadonetreatment1completed
NCT00647907
A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal InfectionsNo drug interventionstreatment4completed
NCT05707156
Prospective Observational Study on the Incidence of Opportunistic Fungal InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT05044156
Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in WomenNo drug interventionsNot AvailableNot Availablecompleted
NCT00001937
Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patientstreatment3completed
NCT01092832
A Study Of The Safety, Tolerability And Effective Of Voriconazole For The Treatment Of Serious Candida Infection And Candida Infection Of The Throat In Pediatric PatientsNo drug interventionstreatment3terminated
NCT02391532
Effect of Probiotic Bacteria on Oral Candida in Frail ElderlyNo drug interventionspreventionNot Availablecompleted
NCT02646800
Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus SppNo drug interventionstreatment4terminated
NCT00099775
Caspofungin to Prevent Candidiasis in Adults in Hospital Intensive Care UnitsNo drug interventionstreatment3completed
NCT00001542
Fluconazole Prophylaxis of Thrush in AIDStreatment4completed
NCT00037219
The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis.treatment2completed
NCT02666716
Pharmacokinetics of Fluconazole IV as Prophylaxis or Therapy to ICU PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00815516
Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal CandidiasisNo drug interventionstreatment3terminated
NCT00095316
Caspofungin Study for Fungal Infections in Adults in Critical Care SettingsNo drug interventionsprevention3terminated
NCT01315925
Pre-hospital Risk Factors for Invasive Fungal InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00000676
Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)prevention3completed
NCT00000744
A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected WomentreatmentNot Availablecompleted
NCT00388167
Acetato de Caspofungin (Cancidas®) in the Treatment of Fungal InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT00304772
Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic PatientsNo drug interventionstreatment4withdrawn
NCT00001810
An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infectionstreatment3completed
NCT03136081
Candida Host Defense Response After Septic Shock in the Critically IllNo drug interventionsNot AvailableNot Availablecompleted
NCT00330395
Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058)No drug interventionstreatment2completed