Menstrual Distress (Dysmenorrhea) (DBCOND0041665)

Identifiers

Synonyms
Dysmenorrhea (Disorder) / Dysmenorrhea / Dysmenorrhoea / Menstrual Cramps / Menstrual cramp / Dysmenorrhea, unspecified / Cramps menstrual / Menstrual cramp (finding) / Period pain present (finding) / Period pains / Menses painful / Pain menstrual / Painful periods

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Acetaminophen
An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
Acetylsalicylic acid
A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
Butylscopolamine
An antispasmodic and anticholinergic agent used for the symptomatic treatment of abdominal cramping and pain.
Choline salicylate
The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
Dexketoprofen
An NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
Diclofenac
An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Dydrogesterone
A synthetic progesterone for menstrual cycle regulation, infertility treatment, prevention of miscarriage, and other conditions.
Ethynodiol diacetate
An oral contraceptive used to prevent pregnancy.
Etofenamate
An NSAID used to treat muscle and joint pain.
Flavoxate
A muscarinic antagonist and spasmolytic used for the symptomatic relief of conditions associated with lack of muscle control in the bladder, such as dysuria, urgency, and nocturia.
Flurbiprofen
An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Ibuprofen
An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
Lynestrenol
A progestin used for contraception and in the treatment of menstrual disorders.
Medazepam
A long-acting benzodiazepine used for its sedative and anxiolytic properties.
Mestranol
A synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
Naproxen
An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
Nimesulide
A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea.
Norgestimate
A progesterone used as a contraceptive and to treat acne vulgaris.
Norgestrel
A progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
Orphenadrine
A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort.
Pipenzolate
An antimuscarinic agent indicated in the treatment of gastrointestinal motility disorders and arrhythmia.
No drug targets
Pitofenone
A medication used in the treatment of spastic pain caused by menstrual cramps, the digestive system, and the urinary tract.
No drug targets
Pyridoxine
A vitamin used to correct vitamin B6 deficiency and to treat nausea during pregnancy.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00740818
Logan Basic and DysmenorrheaNo drug interventionsprevention2unknown_status
NCT04145518
Mechanistic Characterization of Uterine Painhealth_services_research4recruiting
NCT05817513
Effect of Myofascial Release on Scoliotic Females With Dysmenorrhea.No drug interventionstreatmentNot Availablecompleted
NCT06600230
Effect of Pelvic Floor-Based Training on DysmenorrheaNo drug interventionstreatmentNot Availablerecruiting
NCT06294743
Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrheatreatment0recruiting
NCT06398990
The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With DysmenorrhoeaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06075784
The Effect of Reiki on Pain, Stress and Comfort Level in Students Experiencing DysmenorrheaNo drug interventionssupportive_careNot Availablecompleted
NCT05247333
Implementation of a Minor Ailment Service in Community Pharmacy PracticeNo drug interventionshealth_services_researchNot Availablecompleted
NCT03118154
Efficacy of Manual Therapy to Improve Quality of Life and Decrease Pain in Subjects With EndometriosisNo drug interventionsNot AvailableNot Availableterminated
NCT04425577
Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity LengthNo drug interventionsdiagnosticNot Availablecompleted
NCT00212277
Efficacy and Safety,Long-term Study of Low-dose Oral Contraceptive Pill to Treat Dysmenorrhea.treatment3completed
NCT00292747
Drotaverine in Dysmenorrhoea Treatmenttreatment4terminated
NCT02255045
Assessment of a Vaginal Ring With Meloxicam in the Treatment of Dysmenorrheatreatment2 / 3completed
NCT00461305
Safety Study of Ethinylestradiol/Drospirenone in Dysmenorrheatreatment2 / 3completed
NCT00951561
A Comparison Study of Pain Relief From Dysmenorrhea Between the Vipon Tampon and IbuprofentreatmentNot Availablecompleted
NCT00011388
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian ImmigrantsNo drug interventionsNot AvailableNot Availablecompleted
NCT01455285
Effectiveness of the Transcutaneous Electrical Nerve Stimulation in DysmenorrheaNo drug interventionstreatmentNot Availablecompleted
NCT04140175
A Study of Women Receiving Standard of Care (SOC) for the Treatment of Pelvic Pain Due to Suspected or Confirmed Endometriosis and the Impact on the Disease or Symptom Progression.No drug interventionsNot AvailableNot Availableterminated
NCT03448536
A Study to Assess Menstrual Cramp Pain Associated With Primary Dysmenorrheatreatment4completed
NCT03972917
Observation of Long-term Effects on Endometrium and Uterine Fibroids in Women With Ulipristal Acetate TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT05326217
The Effects of Exercise and Probiotics on Dysmenorrhea and MicrobiomeNo drug interventionstreatmentNot Availableunknown_status
NCT05799924
The Study on the Therapeutic Effect and Mechanism of Transcutaneous Acupoint Electrical Stimulation in FemaleNo drug interventionstreatmentNot Availablerecruiting
NCT06321224
Effects of Breathing Exercises on Women With Primary DysmenorheaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01329796
Pertubation With Lignocaine in Endometriosistreatment2completed
NCT02183025
Efficacy and Safety Study of Meloxicam Versus Mefenamic Acid in Patients With Dysmenorrheatreatment2completed
NCT05414825
Dysmenorrhea Exploration in Teenagers, Their Parents and CaregiversNo drug interventionsNot AvailableNot Availablecompleted
NCT05995730
Effect of Lavender Inhalation on DysmenorrheaNo drug interventionssupportive_careNot Availablerecruiting
NCT03697720
Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Paintreatment4completed
NCT03187782
Pulse Diagnoses in Patients While Dysmenorrhea is AttackingNo drug interventionsNot AvailableNot Availablecompleted
NCT06187376
Chinese Herbal Medicine for Gynecologic PatientsNo drug interventionstreatment2withdrawn
NCT06227676
Effect of 'Cramp Bites' on Period Cramps in Women Aged 18-25No drug interventionstreatment2 / 3completed
NCT03230994
Cooperative Adenomyosis NetworkNo drug interventionsNot AvailableNot Availableunknown_status
NCT05355194
Effects of Kinesiotaping With and Without Pelvic Tilts in DysmenorrheaNo drug interventionstreatmentNot Availablecompleted
NCT03269591
Electromagnetic Field Versus Diclofenac Drugs on Primary DysmenorrheatreatmentNot Availablecompleted
NCT00092729
An Investigational Drug Study in the Treatment of Primary Dysmenorrhea (0663-064)treatment3completed
NCT04091789
Sublingual Tablets With Cannabinoid Combinations for the Treatment of DysmenorrheaNo drug interventionstreatment2unknown_status
NCT06364592
Electroacupuncture for Dysmenorrhea Secondary to AdenomyosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03782740
Effect of Melatonin on Reduction of Pelvic Paintreatment2completed
NCT03509740
Intravenous Tramadol Versus Intravenous Paracetamol in Patients With Dysmenorrheatreatment4completed
NCT05624567
Symptoms and Quality of Life of Patients With Suspected EndometriosisNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01738204
The Women's Health Study: From Adolescence to AdulthoodNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03325868
Effect of Ulipristal Acetate on Bleeding Patterns and Dysmenorrhea in Women With Adenomyosistreatment4withdrawn
NCT03697746
Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary DysmenorrheatreatmentNot Availableunknown_status
NCT05461846
Effect of Integrated Neuromuscular Inhibition Technique in Females With Menstrual Low Back PainNo drug interventionstreatmentNot Availableunknown_status
NCT00104546
Vitamin K Injections for the Treatment of Painful MenstruationNo drug interventionstreatment1completed
NCT00902746
Efficacy and Safety, Long-Term Study of NPC-01 to Treat Dysmenorrhea Associated With EndometriosisNo drug interventionstreatment3completed
NCT05829512
Translation, Reliability, and Validity of Turkish Version of the Working Ability, Location, Intensity, Days of Pain, Dysmenorrhea (WaLIDD) ScoreNo drug interventionsNot AvailableNot Availablerecruiting
NCT00357981
Continuous Use of the Contraceptive Patch and the Personal Economic Impact.treatmentNot Availablewithdrawn
NCT04359381
Kinesiotaping Versus Pilate ExercisesNo drug interventionstreatmentNot Availablecompleted
NCT02663050
The Effect of Kinesio Taping Application for DysmenorrheatreatmentNot Availableunknown_status
NCT02372123
The Effect of Connective Tissue Massage in Women With Primary DysmenorrhoeaNo drug interventionstreatmentNot Availablecompleted
NCT02467543
The Efficacy of Viburnum Opulus 3X in the Treatment of Primary DysmenorrheaNo drug interventionstreatment2completed
NCT00769964
VA111913 TS: First in Human StudyNo drug interventionstreatment1completed
NCT01129102
Efficacy and Safety Study of NPC-01 to Treat DysmenorrheaNo drug interventionstreatment3completed
NCT01250587
Dose-Finding Study of PDC31 in Patients With Primary DysmenorrheaNo drug interventionstreatment1completed
NCT05815654
Research and Development of WPAPS Based on the Modern Technology of Traditional Chinese MedicineNo drug interventionstreatmentNot Availablerecruiting
NCT01116453
Randomized Controlled Trial of Acupuncture for DysmenorrheaNo drug interventionstreatment3completed
NCT03394547
Pulsed Electromagnetic Field Treatment for Painful PeriodsNo drug interventionstreatmentNot Availableunknown_status
NCT03064945
The Effectiveness and Safety of LIVIA® Transcutaneous Electrical Nerve Stimulation (TENS) in Women Suffering From Primary Dysmenorrhea.No drug interventionstreatment2completed
NCT00455845
The Effectiveness of Lng IUD for Treatment of the Patient Undergone Conservative Surgery for Pelvic EndometriosisNo drug interventionsprevention3completed
NCT01375998
YAZ Post-marketing Surveillance in JapanNo drug interventionsNot AvailableNot Availablecompleted
NCT01449305
Effectiveness of Nanoone Woman Underwear Using in the Management of DysmenorrheaNo drug interventionshealth_services_researchNot Availablecompleted
NCT05770297
Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant TherapyNo drug interventionssupportive_careNot Availablerecruiting
NCT00511797
SH T00186 Phase II/ III Optimal Drospirenone (DRSP) Dose Finding and Placebo-controlled Comparative Studytreatment2 / 3completed
NCT06011928
MOPEXE and RE in Treating DysmenorrheaNo drug interventionstreatmentNot Availablecompleted
NCT00590811
Prevalence of Menstrual Cycle Related Pain Complains in Adolescents and Young AdultsNo drug interventionsNot AvailableNot Availablecompleted
NCT02362711
Efficacy and Safety, Long-Term Study of NPC-16 to Treat Dysmenorrheatreatment3completed
NCT01670656
A Study to Evaluate the Effect of Contraceptive Vaginal Rings on Primary Dysmenorrhea (P08257/MK-8175A/MK-8342B-057)treatment2completed
NCT00517556
Continuous Administration of Oral Contraceptive, Primary DysmenorrheaNo drug interventionstreatment1 / 2completed
NCT05227456
Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Studytreatment2terminated
NCT05623085
Yoga and Aerobic Exercise Training in Primary DysmenorrheaNo drug interventionstreatmentNot Availablecompleted
NCT04942015
Honghuaruyi Wan for Endometriosis DysmenorrheaNo drug interventionstreatment4unknown_status
NCT00649415
A Double Blind, Double Dummy, Randomized, Comparative Study Of The Efficacy And Safety Of Valdecoxib 40 Mg Twice Daily, As Needed In The First Menstrual Cycle Day And Then Once A Day, And Piroxicam 40 Mg Once A Day In The Treatment Of Patients With Primary Dysmenorrheatreatment4completed
NCT03891537
Neural Therapy Effect and Bilateral Tubal LigationNo drug interventionsNot AvailableNot Availablecompleted
NCT02617537
To Investigate Efficacy of YAZ in the Treatment of Dysmenorrheatreatment3withdrawn
NCT00318500
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Womentreatment2completed
NCT01462370
Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)treatment3completed
NCT00212342
Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Dysmenorrheatreatment3completed
NCT06178406
Brain Structural and Functional Connectivity Changes in the Period of Dysmenorrhea: a Prospective fMRI StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05900336
Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrheaother4recruiting
NCT02197936
Norwegian Adenomyosis Study III: PeristalsisNo drug interventionsNot AvailableNot Availableterminated
NCT00651313
Efficacy and Safety Study of Lidocaine Vaginal Gel for Recurrent Dysmenorrhea (Painful Periods)prevention2completed
NCT00196313
A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Paintreatment2completed
NCT06293313
The Effect of Mindfulness Practice on Coping With Primary Dysmenorrhea on Pain and Anxiety LevelNo drug interventionssupportive_careNot Availablerecruiting
NCT01103518
Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruationtreatment4unknown_status
NCT03881319
The Efficacy of Different Doses of Acupuncture in DysmenorrheaNo drug interventionstreatmentNot Availableunknown_status
NCT00995917
A Pilot Study of Acupoint Injection for Primary DysmenorrheaNo drug interventionstreatmentNot Availablecompleted
NCT01662934
A Randomized, Sham Device Controlled, Single Blinded Trial of Portable Transcutaneous Electrical Nerve Stimulation and Heat Therapy Machine in Women With DysmenorrheaNo drug interventionstreatment3unknown_status
NCT00746096
Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Primary DysmenorrheaNo drug interventionstreatment3completed
NCT00458458
Treatment of Endometriosis With Norethindrone Acetate ( NA) VS. Gonadotropin- Releasing Hormone (GnRH) Agonist (Lupron Depot 11.25 mg)treatment3unknown_status
NCT01626235
AMPED Outcomes Registry of Post-ED Pain ManagementNo drug interventionsNot AvailableNot Availablecompleted
NCT02668822
Efficacy and Safety of Etonogestrel + 17β-Estradiol Vaginal Ring (MK-8342B) in the Treatment of Women With Primary Dysmenorrhea (MK-8342B-060)treatment3terminated
NCT06283225
Pilot Study to Investigate the Effect of a Dysmenorrhoea AppNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06394726
Examining the Impact of Aerobic and Core Exercises on Primary Dysmenorrhea in High School FemalesNo drug interventionstreatmentNot Availablecompleted
NCT04178226
The Efficacy of Two Types of Acupuncture on Autonomic Nervous Activity and Quality of Life in Women With Dysmenorrhea.No drug interventionstreatmentNot Availableunknown_status
NCT00196365
A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Paintreatment3completed
NCT04607382
Survey on Menstrual Symptoms, Health Related Quality of Life and Work Productivity in Patients Suffering From Pain During Menstruation (Dysmenorrhea) in JapanNot AvailableNot Availablecompleted
NCT02237131
Continuous Versus Cyclic Oral Contraceptives for EndometriosisNot Available4unknown_status
NCT03784976
Iyengar Yoga Therapy for Dysmenorrhea and EndometriosisNo drug interventionstreatmentNot Availableunknown_status
NCT00123162
Viagra in the Treatment of Primary Dysmenorrheatreatment1 / 2completed
NCT03761862
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal LigationNo drug interventionsNot AvailableNot Availablecompleted
NCT00855829
A Feasibility Study Designed to Assess the Efficacy of the ActiLady Device in Adult Female Subjects With DysmenorrheaNo drug interventionstreatment1completed
NCT06027489
Listening Music, Drawing on Coping With Dysmenorrhea Complaints of Nursing StudentsNo drug interventionssupportive_careNot Availablecompleted
NCT06353789
Adolescent Dysmenorrhoea as a Risk Factor for Chronic Pain: Clinical Cohort StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02910167
Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N in Adults From Metropolitan LimaNot AvailableNot Availablecompleted
NCT02685501
Menorrhagia, Dysmenorrhea and Iron Deficiency Among Young Women Soldiers and Effect on ActivityNo drug interventionsNot AvailableNot Availableunknown_status
NCT01892904
Comparative Study of BAY86-5300 With a Flexible Extended Regimen for Dysmenorrheatreatment3completed
NCT02373514
IV Paracetamol Versus IV Dexketoprofen in Dysmenorrheatreatment4unknown_status
NCT01289314
Long Term Outcomes Following Total Laparoscopic Hysterectomy and Laparoscopic Supracervical HysterectomyNo drug interventionstreatmentNot Availableunknown_status
NCT04572555
Heat Application on Depression, Anxiety, Menstrual Attitude and DysmenorrheaNo drug interventionssupportive_careNot Availablecompleted
NCT02214550
Chronic Pain Risk Associated With Menstrual Period Paintreatment4completed
NCT02031523
Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating EndometriosisNo drug interventionstreatment4unknown_status
NCT05646238
The Effect of Psychoeducation on Dysmenorrhea in Nursing StudentsNo drug interventionssupportive_careNot Availablecompleted
NCT04618172
Effects of Exercise on the Symptoms of Premenstrual Syndrome and Dysmenorrhoea and Blood Flow of Genital TractNo drug interventionstreatmentNot Availablecompleted
NCT02636972
The Progression From Dysmenorrhoea to Chronic Pelvic PainNo drug interventionsNot AvailableNot Availableunknown_status
NCT00225836
Treatment of Dysmenorrhoea With the OVA TENS ApparatusNo drug interventionstreatmentNot Availablecompleted
NCT06522672
A Study To Assess The Effect Of My Happy Flo On Alleviating Period Symptoms and Heavy Flows.No drug interventionstreatmentNot Availableactive_not_recruiting
NCT02779582
Oral Micronized Progesterone Effects on Perimenopausal Menstrual Flowtreatment3completed