IUD therapy (DBCOND0024306)

Identifiers

Synonyms

IUD / Intrauterine Contraception / Uses intrauterine contraception (finding)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Copper	A transition metal found in a variety of supplements and vitamins, including intravenous solutions for total parenteral nutrition (TPN).	Superoxide dismutase [Cu-Zn]enzyme Diamine oxidase [copper-containing]enzyme Protein-lysine 6-oxidaseenzyme High affinity copper uptake protein 1transporter Natural resistance-associated macrophage protein 2transporter Albumincarrier Alpha-2-macroglobulincarrier Ceruloplasmincarrier Copper transport protein ATOX1carrier Copper-transporting ATPase 1transporter Copper-transporting ATPase 2transporter Copper chaperone for superoxide dismutasecarrier Cytochrome c oxidase copper chaperonecarrier Cytochrome c oxidase subunit 1enzyme Tyrosinaseenzyme Dopamine beta-hydroxylaseenzyme Peptidyl-glycine alpha-amidating monooxygenaseenzyme Monoamine oxidaseenzyme Angiogeninenzyme Amyloid-beta precursor proteintarget Hephaestincarrier Major prion proteinenzyme Adenosylhomocysteinasetarget Coagulation factor Vcarrier Coagulation factor VIIIcarrier Metallothioneincarrier Protein SLC31A2transporter Histone H2B type 1-C/E/F/G/Itarget Glyceraldehyde-3-phosphate dehydrogenasetarget Nucleoside diphosphate kinase Atarget Histone H1.4target Peroxiredoxin-1target Protein S100-A8target Small ribosomal subunit protein uS2target Actin, cytoplasmic 2target Alpha-enolasetarget Elongation factor 1-alpha 1target Keratin, type II cytoskeletal 8target Protein disulfide-isomerasetarget Protein disulfide-isomerase A3target 60 kDa heat shock protein, mitochondrialtarget Heat shock 70 kDa protein 13target Endoplasmic reticulum chaperone BiPtarget Endoplasmintarget Serotransferrintarget Cell growth-regulating nucleolar proteintarget Small ribosomal subunit protein uS5target Serine/arginine-rich splicing factor 1target Heterogeneous nuclear ribonucleoproteins A2/B1target Heterogeneous nuclear ribonucleoprotein Htarget Heterogeneous nuclear ribonucleoprotein H3target Cobalt-precorrin-5B C(1)-methyltransferasetarget Heterogeneous nuclear ribonucleoprotein Ltarget Splicing factor, proline- and glutamine-richtarget Splicing factor 3A subunit 2target Small ribosomal subunit protein RACK1target Alpha-actinin-1target Aminoacylase-1target Annexin A4target Annexin A5target Calreticulintarget Pyruvate kinase PKMtarget Aldo-keto reductase family 1 member A1target NADH-cytochrome b5 reductase 3target Glutathione reductase, mitochondrialtarget Transketolasetarget Peroxiredoxin-2target Peroxiredoxin-6target Peptidyl-prolyl cis-trans isomerase Atarget Heat shock cognate 71 kDa proteintarget Heat shock protein HSP 90-alphatarget Prostaglandin E synthase 3target Stress-induced-phosphoprotein 1target Eukaryotic translation initiation factor 6target Eukaryotic initiation factor 4A-Itarget Glucose-6-phosphate isomerasetarget L-lactate dehydrogenase A chaintarget Phosphoglycerate kinase 1target Tubulin beta chaintarget Cofilin-1target 14-3-3 protein beta/alphatarget Aspartate aminotransferase, cytoplasmictarget Glutathione synthetasetarget Hepatoma-derived growth factortarget Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget Chloride intracellular channel protein 1target Proteasome activator complex subunit 1target Phosphatidylethanolamine-binding protein 1target Phosphoglycerate mutase 1target Ran-specific GTPase-activating proteintarget UDP-glucose 6-dehydrogenasetarget Beta-2-microglobulintarget Protein SCO1 homolog, mitochondrialtarget Alternative prion proteintarget Glycine receptor subunit alpha-1target Huntingtintarget Endonuclease 8-like 1target Endonuclease 8-like 2target Ferroxidase HEPHL1target Plasminogen activator inhibitor 1target Protein S100-A2target Protein S100-A4target Alpha-synucleintarget Brain-derived neurotrophic factortarget Parkinson disease protein 7target Islet amyloid polypeptidetarget Tachykinin-3target Alpha-1B-glycoproteintarget Afamintarget Angiotensinogentarget Alpha-2-HS-glycoproteintarget Serum amyloid P-componenttarget Apolipoprotein A-Itarget Apolipoprotein A-IItarget Apolipoprotein A-IVtarget Apolipoprotein B receptortarget Apolipoprotein C-IItarget Apolipoprotein C-IIItarget Apolipoprotein Dtarget Apolipoprotein Etarget Beta-2-glycoprotein 1target Zinc-alpha-2-glycoproteintarget Complement C1q subcomponent subunit Ctarget Complement C1s subcomponenttarget Complement C3target Complement C4-Btarget C4b-binding protein alpha chaintarget Complement C5target Complement component C8 beta chaintarget Complement component C9target Complement factor Htarget Complement factor Itarget Tetranectintarget Clusterintarget Prothrombintarget Complement component 1 Q subcomponent-binding protein, mitochondrialtarget Gelsolintarget Hemoglobin subunit alphatarget Hemoglobin subunit betatarget Chromobox protein homolog 5target Haptoglobin-related proteintarget Insulin-like growth factor-binding protein complex acid labile subunittarget Immunoglobulin heavy constant gamma 1target Immunoglobulin heavy constant gamma 4target Immunoglobulin kappa variable 3-20target Immunoglobulin lambda-like polypeptide 1target Inter-alpha-trypsin inhibitor heavy chain H2target Kininogen-1target Keratin, type II cytoskeletal 1target Keratin, type I cytoskeletal 10target Keratin, type II cytoskeletal 2 epidermaltarget Keratin, type I cytoskeletal 9target Leucine-rich alpha-2-glycoproteintarget Lumicantarget N-acetylmuramoyl-L-alanine amidasetarget Plasminogentarget Serum paraoxonase/arylesterase 1target Platelet basic proteintarget Alpha-1-antitrypsintarget Kallistatintarget Corticosteroid-binding globulintarget Thyroxine-binding globulintarget Antithrombin-IIItarget Heparin cofactor 2target Pigment epithelium-derived factortarget Alpha-2-antiplasmintarget Plasma protease C1 inhibitortarget Transthyretintarget Vitronectintarget Amyloid beta precursor like protein 1target Tubulin alpha 3C/D chaintarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04927741	Essential Oils Following IUD Insertion	No drug interventions	other	Not Available	completed
NCT06240260	TENS Unit for Analgesia During IUD Insertion	No drug interventions	other	Not Available	recruiting
NCT04379102	The Role Of Local Anesthetics in the Management of Adverse Effects Associated With Intrauterine Device Application	No drug interventions	Not Available	Not Available	completed
NCT06496854	Prescribing Lorazepam for IUD Insertion: Pilot Feasibility Study	Ibuprofen Lorazepam	supportive_care	2	not_yet_recruiting
NCT05283798	Insertion of Copper T380 Versus Multiload IUD Post Partum	No drug interventions	treatment	Not Available	unknown_status
NCT05875571	Intravenous Ketorolac Administration to Attenuate Post-procedural Pain Associated With Intrauterine Device Placement	Ketorolac	treatment	4	recruiting
NCT05187078	Allis Clamp Versus Single-tooth Tenaculum	No drug interventions	supportive_care	Not Available	completed
NCT02076217	Quick Start of Highly Effective Contraception	Copper Levonorgestrel Medroxyprogesterone acetate	Not Available	Not Available	active_not_recruiting
NCT04630548	Safety and Efficacy of Immediate Post Placental IUD Insertion in Patients Undergoing Cesarean Delivery	No drug interventions	health_services_research	Not Available	unknown_status
NCT04932382	Misoprostol Prior to Intrauterine Device Insertion	Misoprostol	prevention	Not Available	completed
NCT05339555	IUD Self-Removal Study	No drug interventions	supportive_care	Not Available	recruiting
NCT04389021	Virtual Reality Simulation for Intrauterine Device Insertion: A Randomized Clinical Trial	No drug interventions	supportive_care	Not Available	completed
NCT06042556	IUD Self-Removal: Evaluating an Online Guide for Self-removal in Clinical and Non-clinical Settings	No drug interventions	other	Not Available	completed
NCT03868137	Multi-dose Ibuprofen Prophylaxis for IUD-insertion	Ibuprofen	treatment	Not Available	unknown_status
NCT04539899	Evaluation of the Influence of the Virtual Reality Helmet on Pain During IUD Insertion	No drug interventions	supportive_care	Not Available	completed
NCT06023849	Trans Caesarean Intra Uterine Contraceptive Device Insertion Versus Conventional Postpartum 6 Weeks Insertion	No drug interventions	health_services_research	Not Available	recruiting
NCT05252117	Uterovaginal Plexus Block With Articaine for Intrauterine Device Placement Patients Who Are Indicated for the Use of Copper IUD as a Contraceptive Method Will be Invited to Participate in This Research.	Articaine Mepivacaine	treatment	4	unknown_status
NCT05383924	Intrauterine Contraceptive Device Insertion During Cesarean Section (CS) Versus Delayed Insertion	No drug interventions	prevention	Not Available	completed
NCT05471362	Barriers of Immediate Postpartum Intrauterine Device Uptake	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT05700812	IUD Placement Without Sounding	No drug interventions	treatment	Not Available	completed
NCT01685164	The Effect of Uterine Size and Posture on Intrauterine Contraception in Nulliparous Women	No drug interventions	Not Available	Not Available	completed
NCT01022645	Postpartum Glucose Tolerance With Levonorgesterel IUD Use in Women With Recent Gestational Diabetes	No drug interventions	Not Available	Not Available	completed
NCT05343546	Ideal Timing of Intrauterine Contraception Insertion After Medical Management of First Trimester Incomplete Abortion	No drug interventions	treatment	Not Available	not_yet_recruiting