Diaper Dermatitis

Also known as: Dermatitis diaper / Nappy rash NOS / Nappy rash / Jacquet's dermatitis / Diaper or napkin rash / Diaper erythema / Diaper Rash

Drug	Drug Name	Drug Description
DB11105	Benzalkonium	An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products.
DB14539	Hydrocortisone acetate	A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis.
DB01110	Miconazole	An azole antifungal with broad-spectrum activity used to treat fungal infections affecting the vagina, mouth and skin, including candidiasis.
DB01593	Zinc	An essential element commonly used for the treatment of patients with documented zinc deficiency.

Drug	Drug Name	Target	Type
DB14539	Hydrocortisone acetate	Annexin A1	target
DB14539	Hydrocortisone acetate	Glucocorticoid receptor	target
DB14539	Hydrocortisone acetate	Sex hormone-binding globulin	carrier
DB14539	Hydrocortisone acetate	Cytochrome P450 3A4	enzyme
DB14539	Hydrocortisone acetate	Cytochrome P450 3A5	enzyme
DB14539	Hydrocortisone acetate	Cytochrome P450 3A7	enzyme
DB14539	Hydrocortisone acetate	P-glycoprotein 1	transporter
DB14539	Hydrocortisone acetate	Solute carrier organic anion transporter family member 1A2	transporter
DB14539	Hydrocortisone acetate	ATP-binding cassette sub-family G member 2	transporter
DB14539	Hydrocortisone acetate	Cytochrome P450 11B1, mitochondrial	enzyme
DB14539	Hydrocortisone acetate	Cytochrome P450 11B2, mitochondrial	enzyme
DB14539	Hydrocortisone acetate	Cytochrome P450 2C8	enzyme
DB14539	Hydrocortisone acetate	Corticosteroid-binding globulin	carrier
DB14539	Hydrocortisone acetate	Corticosteroid 11-beta-dehydrogenase isozyme 2	target
DB14539	Hydrocortisone acetate	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	target
DB14539	Hydrocortisone acetate	Solute carrier family 22 member 8	transporter
DB01110	Miconazole	Cytochrome P450 2C9	enzyme
DB01110	Miconazole	Cytochrome P450 2D6	enzyme
DB01110	Miconazole	Cytochrome P450 3A4	enzyme
DB01110	Miconazole	P-glycoprotein 1	transporter
DB01110	Miconazole	Cytochrome P450 51	target
DB01110	Miconazole	Nitric oxide synthase, endothelial	target
DB01110	Miconazole	Nitric oxide synthase, inducible	target
DB01110	Miconazole	Cytochrome P450 11B1, mitochondrial	enzyme
DB01110	Miconazole	Cytochrome P450 2A6	enzyme
DB01110	Miconazole	Cytochrome P450 2B6	enzyme
DB01110	Miconazole	Cytochrome P450 2C19	enzyme
DB01110	Miconazole	Cytochrome P450 2E1	enzyme
DB01110	Miconazole	Nuclear receptor subfamily 1 group I member 2	target
DB01110	Miconazole	Lanosterol 14-alpha demethylase	enzyme
DB01110	Miconazole	Cytochrome P450 19A1	enzyme
DB01110	Miconazole	Calcium-activated potassium channel	target
DB01110	Miconazole	Voltage-gated Potassium Channels	target
DB01110	Miconazole	Inward rectifier potassium channel	target
DB01110	Miconazole	Voltage gated L-type calcium channel	target
DB01110	Miconazole	Serum albumin	carrier
DB01110	Miconazole	Cytochrome P450 2C8	enzyme
DB01593	Zinc	B1 bradykinin receptor	target
DB01593	Zinc	Methylated-DNA--protein-cysteine methyltransferase	target
DB01593	Zinc	Fructose-bisphosphate aldolase A	target
DB01593	Zinc	Elongation factor 1-alpha 1	target
DB01593	Zinc	Alpha-enolase	target
DB01593	Zinc	Glyceraldehyde-3-phosphate dehydrogenase, testis-specific	target
DB01593	Zinc	Nucleoside diphosphate kinase A	target
DB01593	Zinc	Protein disulfide-isomerase	target
DB01593	Zinc	Protein disulfide-isomerase A3	target
DB01593	Zinc	Peroxiredoxin-1	target
DB01593	Zinc	Phosphoserine phosphatase	target
DB01593	Zinc	Triosephosphate isomerase	target
DB01593	Zinc	Elongation factor Tu, mitochondrial	target
DB01593	Zinc	Estrogen receptor alpha	target
DB01593	Zinc	Interleukin-3	target
DB01593	Zinc	Metallothionein-2	target
DB01593	Zinc	Copper chaperone for superoxide dismutase	target
DB01593	Zinc	Histone deacetylase 1	target
DB01593	Zinc	Histone deacetylase 4	target
DB01593	Zinc	DNA-3-methyladenine glycosylase	target
DB01593	Zinc	Semenogelin-1	target
DB01593	Zinc	Superoxide dismutase [Cu-Zn]	target
DB01593	Zinc	Histone deacetylase 8	target
DB01593	Zinc	Apoptosis regulatory protein Siva	target
DB01593	Zinc	Glycine receptor subunit alpha-1	target
DB01593	Zinc	E3 ubiquitin-protein ligase Mdm2	target
DB01593	Zinc	Insulin	target
DB01593	Zinc	Utrophin	target
DB01593	Zinc	Aspartoacylase	target
DB01593	Zinc	Protein S100-A8	target
DB01593	Zinc	Protein S100-A9	target
DB01593	Zinc	Matrix metalloproteinase-9	target
DB01593	Zinc	Tumor protein p73	target
DB01593	Zinc	Protein S100-A2	target
DB01593	Zinc	Cellular tumor antigen p53	target
DB01593	Zinc	Metallothionein-3	target
DB01593	Zinc	Programmed cell death protein 6	target
DB01593	Zinc	DAN domain family member 5	target
DB01593	Zinc	Metallothionein-1A	target
DB01593	Zinc	Alpha-1B-glycoprotein	target
DB01593	Zinc	Alpha-2-macroglobulin	target
DB01593	Zinc	Angiotensinogen	target
DB01593	Zinc	Alpha-2-HS-glycoprotein	target
DB01593	Zinc	Serum amyloid P-component	target
DB01593	Zinc	Apolipoprotein A-I	target
DB01593	Zinc	Apolipoprotein A-II	target
DB01593	Zinc	Apolipoprotein A-IV	target
DB01593	Zinc	Apolipoprotein B receptor	target
DB01593	Zinc	Apolipoprotein E	target
DB01593	Zinc	Apolipoprotein L1	target
DB01593	Zinc	Complement C1q subcomponent subunit B	target
DB01593	Zinc	Complement C1q subcomponent subunit C	target
DB01593	Zinc	Complement C1r subcomponent	target
DB01593	Zinc	Complement C1s subcomponent	target
DB01593	Zinc	Complement C3	target
DB01593	Zinc	Complement C4-B	target
DB01593	Zinc	C4b-binding protein alpha chain	target
DB01593	Zinc	C4b-binding protein beta chain	target
DB01593	Zinc	Complement C5	target
DB01593	Zinc	Lys-63-specific deubiquitinase BRCC36	target
DB01593	Zinc	Complement component C8 alpha chain	target
DB01593	Zinc	Complement component C8 beta chain	target
DB01593	Zinc	Complement component C8 gamma chain	target
DB01593	Zinc	Complement factor B	target
DB01593	Zinc	Complement factor H	target
DB01593	Zinc	Complement factor I	target
DB01593	Zinc	Clusterin	target
DB01593	Zinc	Ceruloplasmin	target
DB01593	Zinc	Carboxypeptidase N catalytic chain	target
DB01593	Zinc	Carboxypeptidase N subunit 2	target
DB01593	Zinc	Dermcidin	target
DB01593	Zinc	Desmoplakin	target
DB01593	Zinc	Coagulation factor XII	target
DB01593	Zinc	Coagulation factor XIII B chain	target
DB01593	Zinc	Prothrombin	target
DB01593	Zinc	Ficolin-3	target
DB01593	Zinc	Fibrinogen alpha chain	target
DB01593	Zinc	Fibronectin	target
DB01593	Zinc	Gelsolin	target
DB01593	Zinc	Hemoglobin subunit alpha	target
DB01593	Zinc	Hemoglobin subunit beta	target
DB01593	Zinc	Haptoglobin-related protein	target
DB01593	Zinc	Hornerin	target
DB01593	Zinc	Insulin-like growth factor-binding protein complex acid labile subunit	target
DB01593	Zinc	Ig alpha-1 chain C region	target
DB01593	Zinc	Ig mu chain C region	target
DB01593	Zinc	Immunoglobulin kappa variable 1-17	target
DB01593	Zinc	Ig kappa chain V-III region GOL	target
DB01593	Zinc	Immunoglobulin lambda variable 3-21	target
DB01593	Zinc	Inter-alpha-trypsin inhibitor heavy chain H1	target
DB01593	Zinc	Inter-alpha-trypsin inhibitor heavy chain H2	target
DB01593	Zinc	Inter-alpha-trypsin inhibitor heavy chain H3	target
DB01593	Zinc	Inter-alpha-trypsin inhibitor heavy chain H4	target
DB01593	Zinc	Immunoglobulin J chain	target
DB01593	Zinc	Junction plakoglobin	target
DB01593	Zinc	Plasma kallikrein	target
DB01593	Zinc	Kininogen-1	target
DB01593	Zinc	Keratin, type II cytoskeletal 1	target
DB01593	Zinc	Keratin, type I cytoskeletal 10	target
DB01593	Zinc	Keratin, type I cytoskeletal 14	target
DB01593	Zinc	Keratin, type I cytoskeletal 16	target
DB01593	Zinc	Keratin, type II cytoskeletal 2 epidermal	target
DB01593	Zinc	Keratin, type II cytoskeletal 5	target
DB01593	Zinc	Keratin, type II cytoskeletal 6A	target
DB01593	Zinc	Keratin, type I cytoskeletal 9	target
DB01593	Zinc	Alpha-1-acid glycoprotein 2	target
DB01593	Zinc	N-acetylmuramoyl-L-alanine amidase	target
DB01593	Zinc	Serum paraoxonase/arylesterase 1	target
DB01593	Zinc	Pregnancy zone protein	target
DB01593	Zinc	Protein S100-A7	target
DB01593	Zinc	Selenoprotein P	target
DB01593	Zinc	Alpha-1-antitrypsin	target
DB01593	Zinc	Alpha-1-antichymotrypsin	target
DB01593	Zinc	Kallistatin	target
DB01593	Zinc	Corticosteroid-binding globulin	target
DB01593	Zinc	Heparin cofactor 2	target
DB01593	Zinc	Sex hormone-binding globulin	target
DB01593	Zinc	Serotransferrin	target
DB01593	Zinc	Transthyretin	target
DB01593	Zinc	Vitronectin	target
DB01593	Zinc	Amyloid-like protein 1	target
DB01593	Zinc	Amyloid-like protein 2	target
DB01593	Zinc	Amyloid beta A4 protein	target
DB01593	Zinc	Poly [ADP-ribose] polymerase 1	target
DB01593	Zinc	Carbonic anhydrase 1	enzyme

Drug	Drug Name	Phase	Status	Count
DB11112	Lanolin	4	Completed	1
DB00825	Levomenthol	4	Completed	1
DB14123	Menthol	4	Completed	1
DB11058	Petrolatum	4	Completed	1
DB01593	Zinc	4	Completed	1
DB09321	Zinc oxide	4	Completed	1
DB09140	Oxygen	Not Available	Completed	1