Gouty Arthritis

Also known as: Arthritis, Gouty / Gout / Arthritis gouty / Gouty arthropathy / Articular gout / Gout, unspecified / Gout NOS

DrugDrug NameDrug Description
DB00437AllopurinolA xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies.
DB12319BenzbromaroneA uricosuric agent which is taken daily for the prevention of gout flares.
DB04272Citric acidAn anti-chelation additive used in blood collection tubes and as a flavoring and preservative agent in various cosmetic and pharmaceutical products.
DB01285CorticotropinA diagnostic agent used in the screening of patients presumed to have adrenocortical insufficiency.
DB09214DexketoprofenAn NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB01628EtoricoxibA selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
DB04854FebuxostatA xanthine oxidase inhibitor used for the management of chronic hyperuricemia in adults with gout who have an inadequate response or intolerance to allopurinol.
DB01050IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DB11560LesinuradA uric acid 1 transporter inhibitor typically used in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout in patients with inadequate control of uric acid levels with xanthine oxidase inhibitor monotherapy.
DB00423MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB01032ProbenecidA medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
DB09154Sodium citrateAn ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.
DB01138SulfinpyrazoneA platelet inhibitory and uricosuric agent used to inhibit thrombotic and embolic processes and to manage the chronic phases of gout .
DB00605SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
DrugDrug NameTargetType
DB00437AllopurinolXanthine dehydrogenase/oxidasetarget
DB00437AllopurinolSolute carrier family 22 member 8transporter
DB00437AllopurinolSolute carrier family 22 member 7transporter
DB00437AllopurinolAldehyde oxidaseenzyme
DB00437AllopurinolXanthine dehydrogenase/oxidaseenzyme
DB00437AllopurinolATP-binding cassette sub-family G member 2transporter
DB00437AllopurinolSolute carrier family 22 member 2transporter
DB12319BenzbromaroneCytochrome P450 2C9target
DB12319BenzbromaroneCytochrome P450 2C19target
DB12319BenzbromaroneSolute carrier organic anion transporter family member 1B1transporter
DB12319BenzbromaroneSolute carrier organic anion transporter family member 2B1transporter
DB12319BenzbromaroneBile salt export pumptransporter
DB12319BenzbromaroneCytochrome P450 2C19enzyme
DB04272Citric acidBeta-lactamase 2target
DB04272Citric acidAldose reductasetarget
DB04272Citric acidCitrate synthase, mitochondrialtarget
DB04272Citric acidProto-oncogene tyrosine-protein kinase Srctarget
DB04272Citric acidRibonuclease pancreatictarget
DB04272Citric acidIsocitrate dehydrogenase [NADP]target
DB04272Citric acidEosinophil cationic proteintarget
DB04272Citric acidBeta-lactamasetarget
DB04272Citric acidFumarate hydratase class IItarget
DB04272Citric acid6-phosphogluconolactonasetarget
DB04272Citric acidL-amino-acid oxidasetarget
DB04272Citric acidCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1target
DB04272Citric acidCytochrome c peroxidasetarget
DB04272Citric acidHepatocyte growth factor-regulated tyrosine kinase substratetarget
DB04272Citric acidInvasintarget
DB04272Citric acidIntron-associated endonuclease 1target
DB04272Citric acidShort tail fiber proteintarget
DB04272Citric acidMalate dehydrogenase, mitochondrialtarget
DB04272Citric acidN5-carboxyaminoimidazole ribonucleotide mutasetarget
DB04272Citric acid50S ribosomal protein L4target
DB04272Citric acidCarboxypeptidase Btarget
DB04272Citric acidHexon proteintarget
DB04272Citric acidRiboflavin biosynthesis protein RibFtarget
DB04272Citric acidBeta-fructosidasetarget
DB04272Citric acidPutative stringent starvation protein Atarget
DB04272Citric acidCitrate synthasetarget
DB04272Citric acidRNA 3'-terminal phosphate cyclasetarget
DB04272Citric acidU6 snRNA-associated Sm-like protein LSm6target
DB04272Citric acidPleckstrin homology domain-containing family A member 1target
DB04272Citric acidFe(3+)-binding periplasmic proteintarget
DB04272Citric acidSignal recognition particle receptor FtsYtarget
DB04272Citric acidNicotinate-nucleotide adenylyltransferasetarget
DB04272Citric acidN utilization substance protein B homologtarget
DB04272Citric acidComplement component C8 gamma chaintarget
DB04272Citric acidRibonucleoside-diphosphate reductase subunit betatarget
DB04272Citric acidGlutamine synthetase 1target
DB04272Citric acidCitrate synthasetarget
DB04272Citric acidProstaglandin F synthasetarget
DB04272Citric acidAdenine phosphoribosyltransferasetarget
DB04272Citric acidGlucose-1-phosphate thymidylyltransferasetarget
DB04272Citric acidGlyoxalase family proteintarget
DB04272Citric acidLaccase domain protein YfiHtarget
DB04272Citric acidRibose-5-phosphate isomerase Atarget
DB04272Citric acidGMP synthase [glutamine-hydrolyzing]target
DB04272Citric acidInosine triphosphate pyrophosphatasetarget
DB04272Citric acidLysozymetarget
DB04272Citric acidGlycerol uptake operon antiterminator regulatory proteintarget
DB04272Citric acid3-carboxy-cis,cis-muconate cycloisomerasetarget
DB04272Citric acidPyruvate decarboxylasetarget
DB04272Citric acidSolute carrier organic anion transporter family member 2B1transporter
DB04272Citric acidMetallo-beta-lactamase type 2target
DB01285CorticotropinAdrenocorticotropic hormone receptortarget
DB01285CorticotropinCorticoliberintarget
DB01285Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB01285Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB01285Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB01285CorticotropinCytochrome P450 3A4enzyme
DB09214DexketoprofenProstaglandin G/H synthase 1target
DB09214DexketoprofenProstaglandin G/H synthase 2target
DB09214DexketoprofenProstaglandin G/H synthase 1enzyme
DB09214DexketoprofenProstaglandin G/H synthase 2enzyme
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB00586DiclofenacP-glycoprotein 1transporter
DB01628EtoricoxibProstaglandin G/H synthase 2target
DB01628EtoricoxibCytochrome P450 3A4enzyme
DB01628EtoricoxibCytochrome P450 2C9enzyme
DB01628EtoricoxibCytochrome P450 2D6enzyme
DB01628EtoricoxibCytochrome P450 1A2enzyme
DB01628EtoricoxibCytochrome P450 2C19enzyme
DB01628EtoricoxibCytochrome P450 2E1enzyme
DB04854FebuxostatSerum albumincarrier
DB04854FebuxostatXanthine dehydrogenase/oxidasetarget
DB04854FebuxostatUDP-glucuronosyltransferase 1-1enzyme
DB04854FebuxostatUDP-glucuronosyltransferase 1-3enzyme
DB04854FebuxostatUDP-glucuronosyltransferase 1-9enzyme
DB04854FebuxostatUDP-glucuronosyltransferase 2B7enzyme
DB04854FebuxostatCytochrome P450 1A2enzyme
DB04854FebuxostatCytochrome P450 2C8enzyme
DB04854FebuxostatCytochrome P450 2C9enzyme
DB04854FebuxostatATP-binding cassette sub-family G member 2transporter
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenP-glycoprotein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01050IbuprofenCytochrome P450 3A4enzyme
DB11560LesinuradSolute carrier family 22 member 12target
DB11560LesinuradSolute carrier family 22 member 11target
DB11560LesinuradCytochrome P450 2C9enzyme
DB11560LesinuradCytochrome P450 3A4enzyme
DB00423MethocarbamolCarbonic anhydrase 1target
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier
DB01032ProbenecidSolute carrier family 22 member 8target
DB01032ProbenecidSolute carrier family 22 member 11target
DB01032ProbenecidSerum albumincarrier
DB01032ProbenecidSolute carrier family 22 member 2transporter
DB01032ProbenecidSolute carrier family 22 member 1transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 2transporter
DB01032ProbenecidMultidrug resistance-associated protein 4transporter
DB01032ProbenecidMultidrug resistance-associated protein 5transporter
DB01032ProbenecidMonocarboxylate transporter 2transporter
DB01032ProbenecidSolute carrier family 22 member 5transporter
DB01032ProbenecidMultidrug resistance-associated protein 6transporter
DB01032ProbenecidMultidrug resistance-associated protein 1transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1A2transporter
DB01032ProbenecidMonocarboxylate transporter 1transporter
DB01032ProbenecidSodium/bile acid cotransportertransporter
DB01032ProbenecidSolute carrier family 22 member 6transporter
DB01032ProbenecidSolute carrier family 22 member 10transporter
DB01032ProbenecidSolute carrier family 22 member 8transporter
DB01032ProbenecidCanalicular multispecific organic anion transporter 1transporter
DB01032ProbenecidATP-binding cassette sub-family C member 11transporter
DB01032ProbenecidSolute carrier family 22 member 11transporter
DB01032ProbenecidSolute carrier organic anion transporter family member 1C1transporter
DB01032ProbenecidSolute carrier family 22 member 7transporter
DB01032ProbenecidSolute carrier family 22 member 6target
DB01032ProbenecidPannexin-1target
DB01032ProbenecidCytochrome P450 2C8enzyme
DB01032ProbenecidCytochrome P450 3A4enzyme
DB01032ProbenecidSolute carrier family 22 member 12transporter
DB01032ProbenecidSolute carrier family 2, facilitated glucose transporter member 9transporter
DB01032ProbenecidTaste receptor type 2 member 16target
DB01032ProbenecidUDP-glucuronosyltransferase 1-1enzyme
DB01032ProbenecidCytochrome P450 2C9enzyme
DB09154Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
DB09154Sodium citrateSolute carrier family 13 member 2transporter
DB09154Sodium citrateSolute carrier family 13 member 5transporter
DB09154Sodium citrateTricarboxylate transport protein, mitochondrialtransporter
DB01138SulfinpyrazoneMultidrug resistance-associated protein 1target
DB01138SulfinpyrazoneCanalicular multispecific organic anion transporter 1target
DB01138SulfinpyrazoneFatty acid-binding protein, intestinalcarrier
DB01138SulfinpyrazoneCytochrome P450 2C9enzyme
DB01138SulfinpyrazoneCanalicular multispecific organic anion transporter 2transporter
DB01138SulfinpyrazoneMultidrug resistance-associated protein 4transporter
DB01138SulfinpyrazoneMultidrug resistance-associated protein 5transporter
DB01138SulfinpyrazoneMultidrug resistance-associated protein 6transporter
DB01138SulfinpyrazoneMultidrug resistance-associated protein 1transporter
DB01138SulfinpyrazoneCanalicular multispecific organic anion transporter 1transporter
DB01138SulfinpyrazoneCytochrome P450 3A4enzyme
DB01138SulfinpyrazoneCytochrome P450 2B6enzyme
DB01138SulfinpyrazoneCytochrome P450 2C8enzyme
DB01138SulfinpyrazoneSolute carrier family 22 member 12target
DB01138SulfinpyrazoneNuclear receptor subfamily 1 group I member 2target
DB01138SulfinpyrazoneBile salt export pumptransporter
DB00605SulindacProstaglandin G/H synthase 2target
DB00605SulindacAldose reductasetarget
DB00605SulindacProstaglandin G/H synthase 1target
DB00605SulindacMitogen-activated protein kinase 3target
DB00605SulindacPeroxisome proliferator-activated receptor deltatarget
DB00605SulindacProstaglandin D2 receptor 2target
DB00605SulindacSerum albumincarrier
DB00605SulindacSolute carrier family 22 member 6transporter
DB00605SulindacCytochrome P450 1A1enzyme
DB00605SulindacAldo-keto reductase family 1 member B10target
DrugDrug NamePhaseStatusCount
DB01394Colchicine0Completed1
DB00218Moxifloxacin0Not Yet Recruiting1
DB00437Allopurinol1Completed2
DB01394Colchicine1Completed1
DB04854Febuxostat1Completed3
DB00328Indomethacin1Completed1
DB11560Lesinurad1Completed3
DB00788Naproxen1Completed2
DB15129Pegadricase1Unknown Status2
DB00049Rasburicase1Completed1
DB00049Rasburicase1Recruiting1
DB04902Ticagrelor1Completed1
DB08816Ticagrelor1Completed1
DB11873Verinurad1Completed4
DB02134Xanthine1Completed2
DB00437Allopurinol2Completed7
DB00026Anakinra2Not Yet Recruiting1
DB06158Arhalofenate2Completed2
DB11811Arhalofenate2Completed5
DB00993Azathioprine2Completed1
DB12160Bucillamine2Completed1
DB06168Canakinumab2Completed3
DB01394Colchicine2Completed8
DB06643Denosumab2Completed1
DB01234Dexamethasone2Completed1
DB11994Diacerein2Completed1
DB01628Etoricoxib2Not Yet Recruiting1
DB04854Febuxostat2Completed9
DB00448Lansoprazole2Completed1
DB11560Lesinurad2Completed1
DB00788Naproxen2Completed1
DB05321PEG-uricase2Completed2
DB09208Pegloticase2Completed2
DB00635Prednisone2Not Yet Recruiting1
DB00049Rasburicase2Completed1
DB00049Rasburicase2Recruiting2
DB06372Rilonacept2Completed1
DB08811Tofisopam2Unknown Status1
DB07615Tranilast2Completed2
DB12353Ulodesine2Completed4
DB11873Verinurad2Completed3
DB02134Xanthine2Completed1
DB00026Anakinra2 / 3Active Not Recruiting1
DB00959Methylprednisolone2 / 3Active Not Recruiting1
DB00437Allopurinol3Completed9
DB00437Allopurinol3Recruiting2
DB00437Allopurinol3Terminated1
DB06168Canakinumab3Terminated1
DB00482Celecoxib3Completed1
DB01394Colchicine3Completed2
DB16145Dotinurad3Not Yet Recruiting1
DB04854Febuxostat3Completed9
DB04854Febuxostat3Not Yet Recruiting1
DB00328Indomethacin3Completed1
DB00448Lansoprazole3Completed1
DB11560Lesinurad3Completed6
DB00788Naproxen3Completed1
DB05321PEG-uricase3Completed1
DB09208Pegloticase3Completed2
DB06372Rilonacept3Completed2
DB06372Rilonacept3Terminated1
DB00620Triamcinolone3Terminated1
DB00437Allopurinol4Completed6
DB00437Allopurinol4Enrolling by Invitation1
DB08907Canagliflozin4Active Not Recruiting1
DB01394Colchicine4Completed3
DB04854Febuxostat4Completed5
DB04854Febuxostat4Enrolling by Invitation1
DB11560Lesinurad4Terminated1
DB00563Methotrexate4Active Not Recruiting1
DB00563Methotrexate4Completed1
DB00563Methotrexate4Recruiting1
DB00788Naproxen4Completed2
DB00338Omeprazole4Completed1
DB09208Pegloticase4Active Not Recruiting1
DB09208Pegloticase4Completed1
DB09208Pegloticase4Recruiting1
DB00437AllopurinolNot AvailableActive Not Recruiting1
DB00437AllopurinolNot AvailableTerminated1
DB00437AllopurinolNot AvailableUnknown Status1
DB00437AllopurinolNot AvailableWithdrawn1
DB00181BaclofenNot AvailableCompleted1
DB00297BupivacaineNot AvailableCompleted1
DB06774CapsaicinNot AvailableCompleted1
DB01394ColchicineNot AvailableActive Not Recruiting1
DB01394ColchicineNot AvailableRecruiting1
DB01285CorticotropinNot AvailableRecruiting1
DB00924CyclobenzaprineNot AvailableCompleted1
DB00586DiclofenacNot AvailableCompleted1
DB01628EtoricoxibNot AvailableCompleted1
DB04854FebuxostatNot AvailableRecruiting1
DB04854FebuxostatNot AvailableTerminated1
DB00712FlurbiprofenNot AvailableCompleted1
DB00996GabapentinNot AvailableCompleted1
DB01221KetamineNot AvailableCompleted1
DB11560LesinuradNot AvailableWithdrawn1
DB00825LevomentholNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00814MeloxicamNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB00750PrilocaineNot AvailableCompleted1
DB01032ProbenecidNot AvailableActive Not Recruiting1
DB01390Sodium bicarbonateNot AvailableUnknown Status1
DB00669SumatriptanNot AvailableCompleted1
DB00697TizanidineNot AvailableCompleted1
DB00273TopiramateNot AvailableCompleted1
DB08844Uric acidNot AvailableRecruiting1
DB02134XanthineNot AvailableWithdrawn1