| Acetylsalicylic acid | A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. | |
| Amitriptyline | A tricyclic antidepressant indicated in the treatment of depressive illness, either endogenous or psychotic, and to relieve depression associated anxiety. | |
| Atenolol | A synthetic beta-1 selective blocker used in the management of hypertension and chronic angina, and to reduce mortality in known or suspected myocardial infarction in hemodynamically stable patients. | |
| Atogepant | An oral CGRP antagonist used for the preventative therapy of episodic migraine headaches. | |
| Candesartan cilexetil | An angiotensin receptor blocker used to treat hypertension, systolic hypertension, left ventricular hypertrophy, and delay progression of diabetic nephropathy. | |
| Diltiazem | A calcium channel blocker used to treat hypertension and to manage chronic stable angina. | |
| Erenumab | A calcitonin-gene related peptide antagonist used to prevent migraines. | |
| Flavin mononucleotide | A form of vitamin B2 used to restore riboflavin in anemia, migraine, alcoholism, and hyperhomocysteinemia. | |
| Galcanezumab | A calcitonin-gene related peptide antagonist used to prevent migraines and treat cluster headaches. | |
| Guanfacine | An alpha-2A adrenergic receptor agonist used to treat ADHD. | |
| Histamine | An ingredient of topical drugs for the relief of joint pain or muscle aches and pains. | |
| Ibuprofen | An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. | |
| Ketoprofen | An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. | |
| Lisinopril | An ACE inhibitor used to treat hypertension, heart failure, and acute myocardial infarction. | |
| Magnesium citrate | A laxative used in bowel preparation for colonoscopy or as a magnesium supplement. | No drug targets |
| Metoprolol | A beta-blocker used in the treatment of hypertension and angina, and used to reduce mortality due to myocardial infarction. | |
| Nadolol | A non-selective beta-adrenergic antagonist used for the management of arrhythmias, angina pectoris, and hypertension. | |
| Naproxen | An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. | |
| Nicardipine | A calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina. | |
| Pizotifen | A serotonin and tryptamine antagonist indicated for migraine prophylaxis. | |
| Propranolol | A non-selective beta adrenergic antagonist used to treat hypertension, angina, atrial fibrillation, myocardial infarction, migraine, essential tremor, hypertrophic subaortic stenosis, and pheochromocytoma. | |
| Riboflavin | A vitamin used to correct vitamin B2 deficiency. | |
| Timolol | A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. | |
| Topiramate | An anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines. | |
| Ubidecarenone | A cofactor found in various dietary supplements. | |
| Venlafaxine | A selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression, generalized or social anxiety disorder, and panic disorder. | |