Respiratory System Agents
- Name
- Respiratory System Agents
- Accession Number
- DBCAT000132
- Description
Drugs used for their effects on the respiratory system.
- ATC Classification
- Drugs
Drug Drug Description Doxapram A short acting respiratory stimulant used to treat acute respiratory insufficiency in COPD patients. Almitrine For the treatment of chronic obstructive pulmonary disease. Bemegride Bemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose. Omalizumab A monoclonal anti-immunoglobulin E antibody used in the treatment of severe asthma and chronic idiopathic urticaria. Flunisolide An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma. Isoetharine For the treatment of asthma, wheezing, and chronic asthmatic bronchitis. Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Ipratropium An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy. Hyoscyamine For treatment of bladder spasms, peptic ulcer disease, diverticulitis, colic, irritable bowel syndrome, cystitis, and pancreatitis. Also used to treat certain heart conditions, to control the symptoms of Parkinson's disease... Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Montelukast A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Dyphylline A theophylline derivative used to treat asthma, bronchospasm, and COPD. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Nedocromil A pyrano quinoline used to treat allergic conjunctivitis. Orciprenaline A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Benzonatate A non-narcotic oral antitussive drug used to suppress coughing. Terbutaline A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor. Guaifenesin An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses. Bitolterol Used to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive... Oxymetazoline An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. Salmeterol A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Azelastine A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. Formoterol An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. Salbutamol A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms. Cromoglicic acid A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. Isoprenaline A non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine. Cilostazol An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Arformoterol A beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Fenoterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Pirbuterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Procaterol A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Clenbuterol Used as a bronchodilator in the treatment of asthma patients. Bambuterol For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema. Tiotropium A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Pranlukast Used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. Stepronin Strepronin is a mucolytic (expectorant) drug. Ethylmorphine Ethylmorphine is an analgesic used for pain relief. Colforsin Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;... Oxeladin Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. Ularitide Investigated for use/treatment in congestive heart failure. Erdosteine Fro the treatment of chronic bronchitis in adults. Lobeline Investigated for use/treatment in addictions. Ibudilast For the treatment of multiple sclerosis, asthma, and cerebrovascular disease. Acetylcysteine A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. Noscapine Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. Xylometazoline A direct acting sympathomimetic agent used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. Methacholine A parasympathomimetic bronchoconstrictor used during the bronchial challenge test for the diagnosis of bronchial hyperreactivity in subjects who do not have clinically apparent asthma. Naphazoline A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Ambroxol Ambroxol is indicated for secretolytic therapy in bronchoplmonary diseaes with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing. Beractant A pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants. Tetryzoline An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations. Pipazethate For the treatment of cough. Letosteine Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions. Isoaminile Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties. Hexoprenaline Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. Fominoben Fominoben is an antitussive agent. Fenspiride Fenspiride is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. It is approved for use in Russia for the treatment of acute and... Eprazinone Eprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms. Clobutinol Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in... Bromhexine Bromhexine is an expectorant/mucolytic agent. Bromhexine is not available in the United States. It is marketed under the trade name Bisolvon(R) in Germany, England, Belgium, France, Italy, Netherlands, Norway, Sweden,... Olodaterol A long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Potassium citrate An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones. Cirazoline Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed... Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Pholcodine Pholcodine is indicated as a cough suppressant for the temporary relief of non-productive dry cough. It is stated to present a required label indication of "temporary relief of dry cough."... Doxofylline Indicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component. Racepinephrine A bronchodilator used to treat intermittent asthma. Opium A medication used to treat moderate to severe pain. Pentoxyverine A medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis. Normethadone An opioid antitussive used to treat a cough associated with inflamed mucosa. Tulobuterol Tulobuterol has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease. Levodropropizine Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine). Nepadutant Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders. Reproterol Reproterol has been used in trials studying the treatment of Asthma, Exercise-Induced. Oxatomide Oxatomide has been used in trials studying the treatment of Muscular Dystrophy, Duchenne. Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Bamifylline Bamifylline is a selective A1 adenosine receptor antagonist. Oxolamine Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation .... Sobrerol Not Annotated Proxyphylline Not Annotated Guacetisal Not Annotated Zipeprol Not Annotated Etamiphylline Not Annotated Tretoquinol Not Annotated Dropropizine Not Annotated Dimemorfan Not Annotated Bufylline Not Annotated Fluticasone Fluticasone's 2 esters are indicated as inhalers for the treatment and management of asthma by prophylaxis[FDA Label] as well as inflammatory and pruritic dermatoses . A DB00588 nasal spray is... Etamivan Etamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States. Pentetrazol Not Annotated Prethcamide Not Annotated Dimefline Not Annotated Mepixanox Not Annotated Nikethamide Not Annotated Zardaverine Not Available Diphemanil Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. Reslizumab An IL-5 antagonist used as an add-on maintenance treatment of patients with severe eosinophilic asthma in adults. Levopropoxyphene Levopropoxyphene was used as an antitussive. An antitussive is a medication often recommended for the treatment of cough and associated respiratory tract disorders. Its enantiomer, dextropropoxyphene, presents an analgesic effect. Benralizumab A monoclonal antibody used to treat eosinophilic asthma. Sodium metabisulfite Not Annotated - Drugs & Drug Targets