Respiratory System Agents
- Name
- Respiratory System Agents
- Accession Number
- DBCAT000132
- Description
Drugs used for their effects on the respiratory system.
- ATC Classification
- Drugs
Drug Drug Description Doxapram A short acting respiratory stimulant used to treat acute respiratory insufficiency in COPD patients. Almitrine For the treatment of chronic obstructive pulmonary disease. Bemegride Bemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose. Omalizumab A monoclonal anti-immunoglobulin E antibody used in the treatment of severe asthma and chronic idiopathic urticaria. Flunisolide An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma. Isoetharine For the treatment of asthma, wheezing, and chronic asthmatic bronchitis. Theophylline A xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction. Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Ipratropium An anticholinergic drug used in the control of symptoms related to bronchospasm in chronic obstructive pulmonary disease (COPD). Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy. Hyoscyamine An anticholinergic indicated to treat functional gastrointestinal disorders, biliary and renal colic, and acute rhinitis. Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Montelukast A leukotriene receptor antagonist used as part of an asthma therapy regimen, to prevent exercise induced bronchoconstriction, and to treat seasonal allergic rhinitis. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Zafirlukast A leukotriene receptor antagonist used for prophylaxis and chronic treatment of asthma. Atropine A muscarinic antagonist used to treat poisoning by muscarinic agents, including organophosphates and other drugs. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Dyphylline A theophylline derivative used to treat asthma, bronchospasm, and COPD. Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Nedocromil A pyrano quinoline used to treat allergic conjunctivitis. Orciprenaline A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. Enprofylline Used in the management of symptoms of asthma. Also used in the treatment of peripheral vascular diseases and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Benzonatate A non-narcotic oral antitussive drug used to suppress coughing. Terbutaline A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor. Guaifenesin An expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses. Bitolterol Used to dilate air passages in the lungs that have become narrowed as a result of disease or inflammation. It is used in the treatment of asthma and chronic obstructive... Oxymetazoline An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. Salmeterol A long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Azelastine A histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. Formoterol An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. Salbutamol A beta-2 adrenergic receptor agonist used to treat asthma, bronchitis, COPD, as well as prevent exercise induced bronchospasms. Cromoglicic acid A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. Cilostazol An antiplatelet agent and vasodilator used for the symptomatic relief of intermittent claudication. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Aminophylline A bronchodilator consisting of theophylline that is used for the treatment of bronchospasm due to asthma, emphysema and chronic bronchitis. Arformoterol A beta-2 adrenergic agonist and bronchodilator used for long term, symptomatic treatment of reversible bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. Fenoterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Pirbuterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Procaterol A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Clenbuterol A decongestant and bronchodilator used in a variety of respiratory conditions. Bambuterol A long acting beta2-adrenoceptor agonist for the management of lung diseases associated with bronchospasm. Tiotropium A long-acting bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Pranlukast Used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. Theobromine theobromine is used as a vasodilator, a diuretic, and heart stimulant. And similar to caffeine, it may be useful in management of fatigue and orthostatic hypotension. Stepronin Strepronin is a mucolytic (expectorant) drug. Ethylmorphine An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine. Colforsin Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;... Oxeladin Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. Ularitide Investigated for use/treatment in congestive heart failure. Erdosteine A mucolytic agent used to treat conditions characterized by pathological mucus such as respiratory tract infections and chronic obstructive pulmonary disease (COPD). Lobeline Investigated for use/treatment in addictions. Ibudilast For the treatment of multiple sclerosis, asthma, and cerebrovascular disease. Acetylcysteine A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose. Noscapine Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma. Calfactant A lung surfactant for the prophylaxis of respiratory distress syndrome in high-risk infants. Xylometazoline A direct-acting alpha-adrenergic agonist used for the symptomatic treatment of nasal congestion and minor inflammation due to allergies or colds. Methacholine A parasympathomimetic bronchoconstrictor used to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma. Naphazoline A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Ambroxol Ambroxol is indicated for secretolytic therapy in bronchoplmonary disease with abnormal mucus secretion and transport. It allows the mucus to be more easily cleared and ease a patient's breathing. Beractant A pulmonary surfactant used for the treatment and prevention of Respiratory Distress Syndrome (RDS) in premature infants. Tetryzoline An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion. Pipazethate For the treatment of cough. Letosteine Letosteine is a mucolytic used in the treatment of chronic bronchopneumopathies and related conditions. Isoaminile Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties. Hexoprenaline Hexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent. Fominoben Fominoben is an antitussive agent. Fenspiride An oxazolidinone spiro compound with antispasmodic and bronchodilator effects used in the treatment of ENT and respiratory diseases. Eprazinone Eprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms. Clobutinol Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in... Bromhexine A mucolytic drug used to decrease the viscosity of mucus in the airway, enhancing mucus clearance. Olodaterol A long-acting beta2-adrenergic agonist used in the management of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema. Poractant alfa A pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. Potassium citrate An agent used to manage renal tubular acidosis, hypocitraturic calcium oxalate nephrolithiasis, and uric acid lithiasis with or without calcium stones. Cirazoline Cirazoline acts on a number of α adrenergic receptors. It is an agonist of α1A, partial agonist of α1B and α1D, and a nonselective antagonist of α2. It is believed... Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Pholcodine An opioid antitussive used to suppress unproductive coughing. Doxofylline A methylxanthine derivative used in chronic obstructive pulmonary disease, asthma, and bronchospasms. Racepinephrine A bronchodilator used to treat intermittent asthma. Opium A medication used to treat moderate to severe pain. Pentoxyverine A medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis. Normethadone An opioid antitussive used to treat a cough associated with inflamed mucosa. Tulobuterol An inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD. Levodropropizine A peripherally-acting antitussive agent. Nepadutant Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders. Reproterol A short-acting β2 adrenoreceptor agonist used to treat various types of asthma including allergic asthma, non-allergic asthma, and exercise-induced asthma. Oxatomide An antihistamine indicated in the treatment and prevention of allergic symptoms. Terpin hydrate An expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract. Bamifylline A methylxanthine derivative indicated in the treatment of bronchial asthma and other conditions with bronchospasm. Oxolamine A medication indicated in the treatment of a cough or upper respiratory tract inflammation. Sobrerol A mucolytic indicated in patients with chronic respiratory diseases. Proxyphylline Not Annotated Guacetisal Not Annotated Zipeprol Not Annotated Etamiphylline Not Annotated Tretoquinol Not Annotated Dropropizine A peripherally acting cough suppressant. Dimemorfan Not Annotated Bufylline Not Annotated Fluticasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD. Etamivan Etamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States. Pentetrazol A cough suppressant. Prethcamide Not Annotated Dimefline Not Annotated Mepixanox Not Annotated Nikethamide A nicotinic acid derivative indicated as a respiratory stimulant. Zardaverine Not Available Diphemanil Used in the treatment of peptic ulcer, gastric hyperacidity, and hypermotility in gastritis and pylorospasm, and in the treatment of hyperhidrosis (excessive perspiration). Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. Reslizumab An IL-5 antagonist used as an add-on maintenance treatment of patients with severe eosinophilic asthma in adults. Levopropoxyphene Levopropoxyphene was used as an antitussive. An antitussive is a medication often recommended for the treatment of cough and associated respiratory tract disorders. Its enantiomer, dextropropoxyphene, presents an analgesic effect. Benralizumab A monoclonal antibody used to treat eosinophilic asthma. Sodium metabisulfite An ingredient used in products to treat dehydration and replace electrolytes. - Drugs & Drug Targets