Showing BioInteractions for Mitoxantrone (DB01204)

BioInteractor utilizes data on drug-target, -enzyme and -transporter associations to provide insight on drug-drug interactions. It allows you to identify, for instance, which drugs act similarly on the same target. Such drugs may have additive pharmacodynamic effects if given concomitantly. Conversely, two drugs may antagonize the beneficial effects of each other by having opposite actions on a specific drug target. BioInteractor uses ranked drug-enzyme association information to predict enzyme-mediated drug interactions that may be clinically relevant.
Interacting GroupInteracting Drugs
Mitoxantrone is a Cytochrome P450 2E1 substrate
1Cytochrome P450 2E1 substrates1,2-dichlorobenzene, Acetaminophen, Almotriptan, Aminophylline, Aniline, Antipyrine, Benzyl alcohol, Bupropion, Caffeine, Capsaicin, Carvedilol, Cenobamate, Chlorzoxazone, Clevidipine, Dacarbazine, Dalfampridine, Dapsone, Dexloxiglumide, Dexmedetomidine, Dichlorobenzene, Dorzolamide, Enflurane, Enfuvirtide, Estrone, Ethanol, Ethosuximide, Etoposide, Felbamate, Fingolimod, Fomepizole, GTS-21, Halothane, Iloperidone, Isoflurane, Isoniazid, Methoxyflurane, Mexiletine, N-Methyl-N-(Methylbenzyl)Formamide, N,N-dimethylformamide, Nicardipine, Nicotinamide, Nicotine, Nilvadipine, Ondansetron, Paramethadione, Phenacetin, Phenobarbital, Phenytoin, Plitidepsin, Primidone, Propacetamol, Quinidine, Quinine, Selumetinib, Sertraline, Sevoflurane, Sildenafil, Tamoxifen, Tegafur, Thalidomide, Theobromine, Theophylline, Thiamylal, Tirapazamine, Trabectedin, Trimethadione, Umifenovir, Verapamil, Zopiclone
2Cytochrome P450 2E1 inhibitorsAdemetionine, Aldesleukin, Alosetron, Azelastine, Bifonazole, Bromazepam, Chlorpromazine, Chlorzoxazone, Cimetidine, Clascoterone, Clonazepam, Clotrimazole, Desipramine, Dexfenfluramine, Diacerein, Diazepam, Diclofenac, Diethylstilbestrol, Disulfiram, Ditiocarb, Econazole, Ellagic acid, Etoricoxib, Favipiravir, Flunitrazepam, Fluphenazine, Flurazepam, Imipramine, Indisulam, Isoniazid, Isosorbide dinitrate, Itraconazole, Methimazole, Methotrimeprazine, Metyrapone, Miconazole, Midostaurin, Nabilone, Niacin, Nicotinamide, Nicotine, Nifedipine, Nitrazepam, Nortriptyline, Orphenadrine, Osilodrostat, Propofol, Rhein, Rufinamide, Safinamide, Selegiline, Sildenafil, Sulfanilamide, Tegaserod, Thioridazine, Ticlopidine, Tioconazole, Tranylcypromine, Ursodeoxycholic acid, Vayarin, Zafirlukast, Zucapsaicin
3Cytochrome P450 2E1 inducersClofibrate, Colchicine, Delafloxacin, Dexamethasone, Dexamethasone acetate, Ethanol, Fomepizole, Glycerin, Isoniazid, Nicotine, Phenelzine, Phenobarbital, Piperaquine, Primidone, Rifampicin, Streptozocin, Ursodeoxycholic acid
Interacting GroupInteracting Drugs
Mitoxantrone is a Cytochrome P450 2E1 inducer
1Cytochrome P450 2E1 substrates1,2-dichlorobenzene, Acetaminophen, Almotriptan, Aminophylline, Aniline, Antipyrine, Benzyl alcohol, Bupropion, Caffeine, Capsaicin, Carvedilol, Cenobamate, Chlorzoxazone, Clevidipine, Dacarbazine, Dalfampridine, Dapsone, Dexloxiglumide, Dexmedetomidine, Dichlorobenzene, Dorzolamide, Enflurane, Enfuvirtide, Estrone, Ethanol, Ethosuximide, Etoposide, Felbamate, Fingolimod, Fomepizole, GTS-21, Halothane, Iloperidone, Isoflurane, Isoniazid, Methoxyflurane, Mexiletine, N-Methyl-N-(Methylbenzyl)Formamide, N,N-dimethylformamide, Nicardipine, Nicotinamide, Nicotine, Nilvadipine, Ondansetron, Paramethadione, Phenacetin, Phenobarbital, Phenytoin, Plitidepsin, Primidone, Propacetamol, Quinidine, Quinine, Selumetinib, Sertraline, Sevoflurane, Sildenafil, Tamoxifen, Tegafur, Thalidomide, Theobromine, Theophylline, Thiamylal, Tirapazamine, Trabectedin, Trimethadione, Umifenovir, Verapamil, Zopiclone
2Cytochrome P450 2E1 inhibitorsAdemetionine, Aldesleukin, Alosetron, Azelastine, Bifonazole, Bromazepam, Chlorpromazine, Chlorzoxazone, Cimetidine, Clascoterone, Clonazepam, Clotrimazole, Desipramine, Dexfenfluramine, Diacerein, Diazepam, Diclofenac, Diethylstilbestrol, Disulfiram, Ditiocarb, Econazole, Ellagic acid, Etoricoxib, Favipiravir, Flunitrazepam, Fluphenazine, Flurazepam, Imipramine, Indisulam, Isoniazid, Isosorbide dinitrate, Itraconazole, Methimazole, Methotrimeprazine, Metyrapone, Miconazole, Midostaurin, Nabilone, Niacin, Nicotinamide, Nicotine, Nifedipine, Nitrazepam, Nortriptyline, Orphenadrine, Osilodrostat, Propofol, Rhein, Rufinamide, Safinamide, Selegiline, Sildenafil, Sulfanilamide, Tegaserod, Thioridazine, Ticlopidine, Tioconazole, Tranylcypromine, Ursodeoxycholic acid, Vayarin, Zafirlukast, Zucapsaicin
3Cytochrome P450 2E1 inducersClofibrate, Colchicine, Delafloxacin, Dexamethasone, Dexamethasone acetate, Ethanol, Fomepizole, Glycerin, Isoniazid, Nicotine, Phenelzine, Phenobarbital, Piperaquine, Primidone, Rifampicin, Streptozocin, Ursodeoxycholic acid
Interacting GroupInteracting Drugs
Mitoxantrone is a Cytochrome P450 1B1 inhibitor
1Cytochrome P450 1B1 substratesAmodiaquine, Caffeine, Dasatinib, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Flutamide, Melatonin, Progesterone, Tamoxifen, Testosterone, Testosterone undecanoate, Theophylline, Triclabendazole
2Cytochrome P450 1B1 inhibitorsCannabidiol, Daunorubicin, Doxorubicin, Ketoconazole, Medical Cannabis, Melatonin, Nabiximols, Paclitaxel, Propofol, Resveratrol, Tamoxifen
3Cytochrome P450 1B1 inducersBetamethasone, Biotin, Budesonide, Doxorubicin, Hydrocortisone, Lansoprazole, Methylprednisolone, Omeprazole, Prednisolone phosphate, Prednisone, Primaquine, Triclocarban
4Cytochrome P450 1B1 bindersDocetaxel
Interacting GroupInteracting Drugs
Mitoxantrone is a Cytochrome P450 3A4 inhibitor
1Cytochrome P450 3A4 substrates(R)-warfarin, (S)-Warfarin, 3,5-diiodothyropropionic acid, 5-androstenedione, 6-O-benzylguanine, 7-ethyl-10-hydroxycamptothecin, 9-aminocamptothecin, Abemaciclib, Abiraterone, Acalabrutinib, Acenocoumarol, Acetaminophen, Adinazolam, Agmatine, Albendazole, Alclometasone, Aldesleukin, Aldosterone, Alfentanil, Alfuzosin, Aliskiren, Almotriptan, Alogliptin, Alosetron, Alpelisib, alpha-Tocopherol acetate, Alprazolam, Ambrisentan, Ambroxol, Amcinonide, Aminophenazone, Aminophylline, Amiodarone, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Androstenedione, Antipyrine, Apalutamide, Apixaban, Apremilast, Aprepitant, Aranidipine, Argatroban, Aripiprazole, Aripiprazole lauroxil, Artemether, Asenapine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Avanafil, Avapritinib, Axitinib, Azelastine, Azelnidipine, Azimilide, Azithromycin, Balaglitazone, Baloxavir marboxil, Banoxantrone, Baricitinib, Barnidipine, Beclomethasone dipropionate, Bedaquiline, Belinostat, Bencyclane, Benidipine, Benzodiazepine, Benzphetamine, Bepridil, Betamethasone, Betamethasone phosphate, Bexarotene, Bezafibrate, Bicalutamide, Bictegravir, Bimatoprost, Bioallethrin, Bisoprolol, Blonanserin, Boceprevir, Bortezomib, Bosentan, Bosutinib, Brentuximab vedotin, Brexpiprazole, Brigatinib, Brinzolamide, Brivaracetam, Bromocriptine, Brotizolam, Budesonide, Bupivacaine, Buprenorphine, Buspirone, Busulfan, Butyrfentanyl, Cabazitaxel, Cabergoline, Cabozantinib, Caffeine, Calanolide A, Calcitriol, Canagliflozin, Cannabidiol, Capmatinib, Capravirine, Carbamazepine, Carboxyamidotriazole, Cariprazine, Caroverine, Carvedilol, Celecoxib, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Cevimeline, Chenodeoxycholic acid, Chlormadinone, Chloroquine, Chlorpheniramine, Chlorzoxazone, Cholecalciferol, Ciclesonide, Ciglitazone, Cilnidipine, Cilostazol, Cinacalcet, Cinnarizine, Cisapride, Citalopram, Clarithromycin, Clevidipine, Clindamycin, Clobazam, Clobetasol, Clobetasol propionate, Clobetasone, Clofibrate, Clomethiazole, Clomipramine, Clonazepam, Clonidine, Clopidogrel, Clorazepic acid, Clotiazepam, Clotrimazole, Clozapine, Cobicistat, Cobimetinib, Cocaine, Codeine, Colchicine, Conivaptan, Conjugated estrogens, Copanlisib, Corticosterone, Corticotropin, Cortisone acetate, Crizotinib, Cyclandelate, Cyclobenzaprine, Cyclophosphamide, Cyclosporine, Cyproterone acetate, Cytarabine, Dabrafenib, Daclatasvir, Dacomitinib, Dapagliflozin, Dapoxetine, Dapsone, Darifenacin, Darodipine, Darolutamide, Darunavir, Dasabuvir, Dasatinib, Daunorubicin, Deflazacort, Delamanid, Delavirdine, Demegestone, Desipramine, Desogestrel, Desonide, Desoxycorticosterone acetate, Desoxycorticosterone pivalate, Desvenlafaxine, Deutetrabenazine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dexchlorpheniramine maleate, Dexlansoprazole, Dexloxiglumide, Dexniguldipine, Dextromethorphan, Dextropropoxyphene, Dexverapamil, Diazepam, Diclofenac, Dienogest, Diethylstilbestrol, Difluocortolone, Difluprednate, Digitoxin, Dihydro-alpha-ergocryptine, Dihydrocodeine, Dihydroergocornine, Dihydroergocristine, Dihydroergocryptine, Dihydroergotamine, Diltiazem, Diphenadione, Disopyramide, Disulfiram, Docetaxel, Dofetilide, Dolasetron, Domperidone, Donepezil, Doravirine, Dotarizine, Doxazosin, Doxepin, Doxorubicin, Doxycycline, Dronabinol, Dronedarone, Drospirenone, Duvelisib, Dydrogesterone, Ebastine, Efavirenz, Efonidipine, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Elvitegravir, Emopamil, Enasidenib, Encorafenib, Enfortumab vedotin, Entrectinib, Enzalutamide, Eperisone, Epinastine, Eplerenone, Equilenin, Equilin, Eravacycline, Erdafitinib, Ergoloid mesylate, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Escitalopram, Esketamine, Esomeprazole, Estazolam, Esterified estrogens, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estramustine, Estrone, Estrone sulfate, Eszopiclone, Ethanol, Ethinylestradiol, Ethosuximide, Ethyl biscoumacetate, Ethylmorphine, Ethynodiol diacetate, Etizolam, Etonogestrel, Etoposide, Etoricoxib, Etravirine, Etynodiol, Everolimus, Exemestane, Fedratinib, Felbamate, Felodipine, Fendiline, Fenfluramine, Fentanyl, Fesoterodine, Finasteride, Fish oil, Flibanserin, Flucloxacillin, Fludrocortisone, Flumethasone, Flunarizine, Flunisolide, Flunitrazepam, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluoxetine, Fluprednidene, Fluprednisolone, Fluprednisolone acetate, Flurandrenolide, Flurazepam, Fluspirilene, Flutamide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fosphenytoin, Fostamatinib, Fostemsavir, Fulvestrant, Fusidic acid, Galantamine, Gallopamil, Gefitinib, Gemfibrozil, Gestodene, Gestrinone, Gilteritinib, Glasdegib, Glyburide, Granisetron, Grazoprevir, Grepafloxacin, Guanfacine, Halcinonide, Halofantrine, Haloperidol, Halothane, HE3286, Hydrocodone, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone cypionate, Hydrocortisone phosphate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Hydroxychloroquine, Hydroxyprogesterone, Hydroxyprogesterone caproate, Hydroxyzine, Ibrutinib, Ibuprofen, Icotinib, Idelalisib, Ifosfamide, Iloperidone, Imatinib, Imidafenacin, Imipramine, Imiquimod, Indacaterol, Indalpine, Indapamide, Indinavir, Ipecac, Irinotecan, Isavuconazole, Isavuconazonium, Isotretinoin, Isradipine, Istradefylline, Itraconazole, Ivabradine, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ixazomib, Ketamine, Ketazolam, Ketobemidone, Ketoconazole, Lacidipine, Lacosamide, Lansoprazole, Lapatinib, Laquinimod, Larotrectinib, Lefamulin, Lemborexant, Lenvatinib, Lercanidipine, Letrozole, Levacetylmethadol, Levamlodipine, Levobupivacaine, Levocetirizine, Levomenthol, Levomilnacipran, Levonorgestrel, Lidocaine, Lidoflazine, Linagliptin, Liotrix, Lisuride, Lobeglitazone, Lomerizine, Lomitapide, Loperamide, Lopinavir, Loratadine, Lorazepam, Lorcaserin, Lorpiprazole, Losartan, Loteprednol etabonate, Lovastatin, Lumefantrine, Lurasidone, Lurbinectedin, Lynestrenol, Lysergic acid diethylamide, Macimorelin, Macitentan, Manidipine, Maraviroc, Medrogestone, Medroxyprogesterone acetate, Medrysone, Mefloquine, Megestrol acetate, Melengestrol, Meloxicam, Meperidine, Meprednisone, Mestranol, Methadone, Methaqualone, Methotrexate, Methoxyflurane, Methylergometrine, Methylprednisolone, Methylprednisone, Methyltestosterone, Methysergide, Metoclopramide, Metoprolol, Mexazolam, Mexiletine, Mianserin, Mibefradil, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Mirabegron, Mirtazapine, Modafinil, Mometasone, Mometasone furoate, Montelukast, Morphine, Mycophenolate mofetil, Nabiximols, Naftopidil, Naloxegol, Nateglinide, Nebivolol, Nefazodone, Nelfinavir, Neratinib, Netoglitazone, Netupitant, Nevirapine, Nicardipine, Nicotine, Nifedipine, Niguldipine, Nilotinib, Niludipine, Nilvadipine, Nimesulide, Nimodipine, Nintedanib, Nisoldipine, Nitrazepam, Nitrendipine, Nomegestrol, Nomegestrol acetate, Norelgestromin, Norethindrone enanthate, Norethisterone, Norethynodrel, Norgestimate, Norgestrel, Nortriptyline, Nylidrin, Odanacatib, Olaparib, Oliceridine, Olopatadine, Omeprazole, Ondansetron, Opium, Orphenadrine, Osilodrostat, Osimertinib, Ospemifene, Otilonium, Oxybutynin, Oxycodone, Oxymorphone, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Palonosetron, Panobinostat, Pantoprazole, Paramethadione, Paramethasone, Parecoxib, Paricalcitol, Paritaprevir, Paroxetine, Pazopanib, Pemigatinib, Penfluridol, Perampanel, Perhexiline, Perospirone, Perphenazine, Pexidartinib, Phenacetin, Phenprocoumon, Phentermine, Phenytoin, Pimecrolimus, Pimozide, Pinacidil, Pinaverium, Pioglitazone, Piperaquine, Pipotiazine, Pitolisant, Plitidepsin, Polatuzumab vedotin, Pomalidomide, Ponatinib, Posaconazole, Pranlukast, Prasugrel, Prazepam, Praziquantel, Prednicarbate, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Prednylidene, Pregnenolone, Prenylamine, Pretomanid, Primaquine, Progesterone, Promazine, Promegestone, Propacetamol, Propafenone, Propiverine, Propranolol, Prucalopride, Quazepam, Quetiapine, Quinacrine, Quingestanol, Quinidine, Quinine, Rabeprazole, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Remdesivir, Repaglinide, Retapamulin, Ribociclib, Rifabutin, Rifalazil, Rifapentine, Rifaximin, Rilpivirine, Rimegepant, Rimexolone, Rimonabant, Riociguat, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Rivoglitazone, Rofecoxib, Roflumilast, Rolapitant, Romidepsin, Ropivacaine, Rosiglitazone, Rotigotine, Roxithromycin, Rucaparib, Rufinamide, Rupatadine, Ruxolitinib, Safinamide, Salmeterol, Saquinavir, Saxagliptin, Segesterone acetate, Selegiline, Seletracetam, Selexipag, Selinexor, Selpercatinib, Selumetinib, Seratrodast, Sertindole, Sertraline, Sevoflurane, Sibutramine, Sildenafil, Silodosin, Simeprevir, Simvastatin, Siponimod, Sirolimus, Sitagliptin, Solifenacin, Sonidegib, Sorafenib, St. John's Wort, Sufentanil, Sulfadiazine, Sulfamethoxazole, Sulfinpyrazone, Sunitinib, Suvorexant, Synthetic Conjugated Estrogens, A, Synthetic Conjugated Estrogens, B, Tacrolimus, Tadalafil, Tamoxifen, Tamsulosin, Tasimelteon, Tasosartan, Taurochenodeoxycholic acid, Tazemetostat, Telaprevir, Telithromycin, Temazepam, Temsirolimus, Tenapanor, Teniposide, Tenofovir, Tenofovir alafenamide, Terbinafine, Terfenadine, Terguride, Terodiline, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone propionate, Testosterone undecanoate, Tetracycline, Tetrahydropalmatine, Tetrandrine, Tezacaftor, Theophylline, Thiamylal, Thiotepa, Tiagabine, Tianeptine, Ticagrelor, Tinidazole, Tiotropium, Tipranavir, Tocofersolan, Tocopherol, Tofacitinib, Tolfenamic acid, Tolterodine, Tolvaptan, Toremifene, Trabectedin, Tramadol, Tranilast, Trastuzumab deruxtecan, Trastuzumab emtansine, Trazodone, Tretinoin, Triamcinolone, Triazolam, Triclabendazole, Trifarotene, Trimebutine, Trimethadione, Trimethoprim, Troleandomycin, Ubrogepant, Udenafil, Ulipristal, Umifenovir, Upadacitinib, Valbenazine, Valdecoxib, Vandetanib, Vanoxerine, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vicriviroc, Vilanterol, Vilazodone, Vinblastine, Vincristine, Vindesine, Vinflunine, Vinorelbine, Vinpocetine, Vismodegib, Vitamin D, Vitamin E, Vorapaxar, Voriconazole, Vortioxetine, Voxelotor, Voxilaprevir, Warfarin, WIN 55212-2, Yohimbine, Zafirlukast, Zaleplon, Zanubrutinib, Zidovudine, Zileuton, Ziprasidone, Zolpidem, Zomepirac, Zonisamide, Zopiclone, Zotepine, Zuclopenthixol
2Cytochrome P450 3A4 inducersAcetaminophen, Amcinonide, Aminoglutethimide, Amprenavir, Apalutamide, Aprepitant, Aprobarbital, Armodafinil, Artemether, Asunaprevir, Avasimibe, Azatadine, Barbital, Beclomethasone dipropionate, Betamethasone, Betamethasone phosphate, Bexarotene, Bosentan, Budesonide, Calcitriol, Carbamazepine, Cefradine, Cenobamate, Cerivastatin, Chlorphenesin, Chlorpromazine, Clevidipine, Clobazam, Clobetasol, Clobetasol propionate, Clocortolone acetate, Clofazimine, Clofibrate, Cloprednol, Clotrimazole, Clozapine, Corticotropin, Cortisone, Cortisone acetate, Cortivazol, Cyclophosphamide, Dabrafenib, Deferasirox, Deflazacort, Delafloxacin, Desonide, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dicloxacillin, Difluocortolone, Echinacea, Efavirenz, Enasidenib, Enzalutamide, Esketamine, Eslicarbazepine, Eslicarbazepine acetate, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Ethanol, Etoposide, Etravirine, Felbamate, Flucloxacillin, Flunisolide, Fluocinolone acetonide, Fluocinonide, Fluocortolone, Fluorometholone, Fluprednidene, Fluprednidene acetate, Fluticasone, Fluticasone furoate, Formestane, Fosaprepitant, Fosphenytoin, Genistein, Glycerol phenylbutyrate, Griseofulvin, Halometasone, Hydrocortamate, Hydrocortisone, Hydrocortisone aceponate, Hydrocortisone acetate, Hydrocortisone butyrate, Hydrocortisone probutate, Hydrocortisone succinate, Hydrocortisone valerate, Idelalisib, Ifosfamide, Isavuconazole, Isavuconazonium, Ivermectin, Ivosidenib, Ketamine, Lansoprazole, Lenvatinib, Lesinurad, Lumacaftor, Lumefantrine, Medroxyprogesterone acetate, Medrysone, Melengestrol acetate, Meperidine, Meprednisone, Metamizole, Methadone, Methylprednisolone, Methylprednisolone hemisuccinate, Metyrapone, Midostaurin, Mifepristone, Mitotane, Modafinil, Mometasone, Mometasone furoate, Nafcillin, Nevirapine, Nifedipine, Norgestimate, Omeprazole, Oritavancin, Orlistat, Osimertinib, Oxcarbazepine, Oxiconazole, Paclitaxel, Paramethasone, Pegvisomant, Pentobarbital, Perampanel, Pexidartinib, Phenobarbital, Phenylbutazone, Phenytoin, Pioglitazone, Pitolisant, Prednicarbate, Prednisolone, Prednisolone acetate, Prednisolone hemisuccinate, Prednisolone phosphate, Prednisone, Prednisone acetate, Prednylidene, Primidone, Probenecid, Progesterone, Propacetamol, Quinine, Rifabutin, Rifampicin, Rifamycin, Rifapentine, Rifaximin, Rimexolone, Rofecoxib, Rufinamide, Sarilumab, Seratrodast, Siltuximab, St. John's Wort, Sulfinpyrazone, Tamoxifen, Terbinafine, Terfenadine, Tesmilifene, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Thiamylal, Tocilizumab, Topiramate, Topotecan, Trametinib, Triamcinolone, Troglitazone, Vemurafenib, Vinblastine, Vitamin E, Warfarin
3Cytochrome P450 3A4 inhibitors6-Deoxyerythronolide B, 7-ethyl-10-hydroxycamptothecin, Abametapir, Abemaciclib, Abiraterone, Acalabrutinib, Acetazolamide, Aldesleukin, Amiodarone, Amphotericin B, Amprenavir, Anastrozole, Aprepitant, Arsenic trioxide, Astemizole, Atazanavir, AVE9633, Azelastine, Azithromycin, Barnidipine, Benidipine, Bicalutamide, Bifonazole, Black cohosh, Boceprevir, Bosutinib, Brefeldin A, Brentuximab vedotin, Bromocriptine, Bryostatin 1, Buprenorphine, Cabergoline, Candicidin, Capsaicin, Carbomycin, Caspofungin, Cenobamate, Ceritinib, Cerivastatin, Cethromycin, Chloramphenicol, Chlorzoxazone, Cimetidine, Ciprofloxacin, Citalopram, Clarithromycin, Clascoterone, Clevidipine, Clindamycin, Clofazimine, Clotrimazole, Clozapine, Cobicistat, Colchicine, Coltuximab ravtansine, Conivaptan, Crizotinib, Curcumin, Curcumin sulfate, Cyclosporine, Cyproterone acetate, Dalfopristin, Danazol, Danoprevir, Dapoxetine, Darunavir, Dasatinib, Daunorubicin, Delavirdine, Desipramine, Desvenlafaxine, Dexamethasone, Dexamethasone acetate, Dexamethasone isonicotinate, Dextropropoxyphene, Diazepam, Diclofenac, Diethylstilbestrol, Dihydroergotamine, Diltiazem, Dimethyl sulfoxide, Dirithromycin, Ditiocarb, Docetaxel, Doramectin, Dovitinib, Doxorubicin, Doxycycline, Dronedarone, Econazole, Edetate calcium disodium anhydrous, Edetate disodium anhydrous, Efavirenz, Efonidipine, Elbasvir, Elexacaftor, Elvitegravir, Enasidenib, Epinephrine, Epofolate, Epothilone D, Eprinomectin, Ergotamine, Erlotinib, Erythromycin, Ethanol, Etoposide, Etoricoxib, Ezetimibe, Felodipine, Fidaxomicin, Fluconazole, Fluoxetine, Flurithromycin, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fluvastatin, Fluvoxamine, Fosamprenavir, Fosaprepitant, Fosnetupitant, Fostamatinib, Fusidic acid, Gefitinib, Ginkgo biloba, Glecaprevir, Glyburide, GPI-1485, Haloperidol, Hydralazine, Idelalisib, Ifosfamide, Imatinib, Indalpine, Indinavir, Indisulam, Irbesartan, Isavuconazole, Isavuconazonium, Isradipine, Itraconazole, Ivacaftor, Ixabepilone, Ketazolam, Ketoconazole, Kitasamycin, KOS-1584, Lanreotide, Lansoprazole, Lapatinib, Lenvatinib, Lercanidipine, Lestaurtinib, Letermovir, Levosalbutamol, Linagliptin, Lomustine, Loperamide, Lopinavir, Loratadine, Lorvotuzumab mertansine, Losartan, Lovastatin, Luliconazole, Manidipine, Medical Cannabis, Mefloquine, Mepartricin, Mequitazine, Methadone, Methimazole, Methylene blue, Methylergometrine, Metronidazole, Metyrapone, Mibefradil, Miconazole, Midazolam, Midecamycin, Midostaurin, Mifepristone, Milnacipran, Miocamycin, Mirtazapine, Mirvetuximab Soravtansine, Mitemcinal, Naloxone, Natamycin, Nefazodone, Nelfinavir, Netupitant, Niacin, Nicardipine, Nicotinamide, Nifedipine, Nilotinib, Nilvadipine, Nitric Oxide, Norfloxacin, Noscapine, Octreotide, Olanzapine, Olaparib, Oleandomycin, Omeprazole, Oritavancin, Orphenadrine, Osilodrostat, Osimertinib, Oxcarbazepine, Oxetacaine, Oxybutynin, Oxymetholone, Palbociclib, Paramethasone, Paroxetine, Pasireotide, Patupilone, Pazopanib, Peppermint oil, Pergolide, Pexidartinib, Phenelzine, Pilocarpine, Pimecrolimus, Pimozide, Piperaquine, Piperine, Posaconazole, Primaquine, Quinidine, Quinine, Quinupristin, Rabeprazole, Raloxifene, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Remacemide, Remdesivir, Resveratrol, Ribociclib, Ridaforolimus, Rifamycin, Rilpivirine, Rimegepant, Ritonavir, Rokitamycin, Roxithromycin, Rucaparib, Rutin, Sagopilone, Salbutamol, Saquinavir, Saracatinib, Sarilumab, Selamectin, Seproxetine, Simeprevir, Sitaxentan, Solithromycin, Somatostatin, Sorafenib, Stiripentol, Sulfanilamide, Sunitinib, Tamoxifen, Telaprevir, Telithromycin, Teniposide, Terfenadine, Tesmilifene, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetracycline, Ticagrelor, Tildipirosin, Tilmicosin, Tioconazole, Tipranavir, Tofisopam, Topiroxostat, Topotecan, Toremifene, Trastuzumab emtansine, Triclabendazole, Troleandomycin, Tylosin, Tylvalosin, Valproic acid, Vapreotide, Venetoclax, Verapamil, Vinblastine, Voriconazole, WIN 55212-2, Zafirlukast, Zimelidine
Interacting GroupInteracting Drugs
Mitoxantrone is a P-glycoprotein 1 substrate
1P-glycoprotein 1 inducersAcetylsalicylic acid, Aldosterone, Amiodarone, Amprenavir, Apalutamide, Atazanavir, Beclomethasone dipropionate, Betamethasone phosphate, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Colchicine, Darunavir, Daunorubicin, Dexamethasone, Dexamethasone acetate, Diclofenac, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Hydrocortisone, Indinavir, Ivermectin, Levothyroxine, Liothyronine, Liotrix, Lopinavir, Lumacaftor, Methylprednisolone, Mifepristone, Nefazodone, Nelfinavir, Nifedipine, Phenobarbital, Platelet Activating Factor, Prednisolone phosphate, Prednisone, Progesterone, Propofol, Reserpine, Rifabutin, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Tipranavir, Trazodone, Vinblastine, Vincristine
2P-glycoprotein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Alectinib, Alfentanil, Alpelisib, Amiodarone, Amlodipine, Amodiaquine, Amsacrine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Axitinib, Azelastine, Azithromycin, Benzocaine, Bepridil, Bicalutamide, Biricodar, Bisoprolol, Boceprevir, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carfilzomib, Carvedilol, Caspofungin, Ceftriaxone, Cethromycin, Cetirizine, Chloroquine, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colforsin, Concanamycin A, Conivaptan, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dacomitinib, Dactinomycin, Darunavir, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexamethasone acetate, Dexniguldipine, Dexverapamil, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Dovitinib, Doxazosin, Doxorubicin, Dronabinol, Dronedarone, Duloxetine, Elacridar, Elagolix, Elbasvir, Elexacaftor, Emopamil, Enalapril, Enasidenib, Entrectinib, Enzalutamide, Erdafitinib, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Esomeprazole, Estramustine, Etoposide, Favipiravir, Fedratinib, Felodipine, Fentanyl, Fingolimod, Flibanserin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Galantamine, Gallopamil, Gefitinib, Genistein, Glasdegib, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Hydroxychloroquine, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Istradefylline, Itraconazole, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ketoconazole, Lamotrigine, Laniquidar, Lansoprazole, Lapatinib, Lasmiditan, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lonafarnib, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Lurbinectedin, Medroxyprogesterone acetate, Mefloquine, Megestrol acetate, Methadone, Methylene blue, Metronidazole, Mibefradil, Miconazole, Mifepristone, Mirabegron, Mitotane, Naproxen, Nefazodone, Nelfinavir, Neratinib, Netupitant, Nicardipine, Niguldipine, Nilotinib, Nintedanib, Nisoldipine, Nitrendipine, Norethisterone, Norgestimate, Olaparib, Omeprazole, ONT-093, Paclitaxel, Palbociclib, Paliperidone, Pantoprazole, Paroxetine, Pemigatinib, Pibrentasvir, Pimozide, Piperine, Polyethylene glycol, Polyethylene glycol 400, Ponatinib, Posaconazole, Prazosin, Primaquine, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rifamycin, Rilpivirine, Ripretinib, Ritonavir, Rolapitant, Rucaparib, Salinomycin, Saquinavir, Sarecycline, Scopolamine, Selegiline, Selpercatinib, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Tamoxifen, Tariquidar, Taurocholic acid, Telaprevir, Telmisartan, Temsirolimus, Tenofovir disoproxil, Terazosin, Terfenadine, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Tezacaftor, Ticagrelor, Tipifarnib, Tipranavir, Tolvaptan, Trifluoperazine, Triflupromazine, Troleandomycin, Upadacitinib, Valinomycin, Valspodar, Vandetanib, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine, Zonisamide, Zosuquidar
3P-glycoprotein 1 substratesAbemaciclib, Acebutolol, Acenocoumarol, Acetaminophen, Acetylsalicylic acid, Afatinib, Albendazole, Aldosterone, Alectinib, Aliskiren, Alitretinoin, alpha-Tocopherol acetate, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Apixaban, Apremilast, Arsenic trioxide, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Avatrombopag, Axitinib, Azathioprine, Azithromycin, Baricitinib, Beclomethasone dipropionate, Belantamab mafodotin, Belinostat, Betamethasone, Betamethasone phosphate, Betrixaban, Bisoprolol, Bortezomib, Bosutinib, Bromocriptine, Budesonide, Cabazitaxel, Cabergoline, Camptothecin, Canagliflozin, Capmatinib, Carfilzomib, Celecoxib, Ceritinib, Cerivastatin, Cethromycin, Cetirizine, Chloramphenicol succinate, Chloroquine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Daclatasvir, Dacomitinib, Dactinomycin, Dapagliflozin, Darolutamide, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquine, Dexamethasone, Dexamethasone acetate, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxepin, Doxorubicin, Duvelisib, Edoxaban, Elagolix, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Empagliflozin, Enasidenib, Enfortumab vedotin, Entrectinib, Epinastine, Erdafitinib, Erlotinib, Ertugliflozin, Erythromycin, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinylestradiol, Etoposide, Everolimus, Ezetimibe, Fedratinib, Fesoterodine, Fexofenadine, Fidaxomicin, Flecainide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fostemsavir, Gefitinib, Gemcitabine, Gilteritinib, Glasdegib, Glecaprevir, Gramicidin D, Grapiprant, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Hydroxyzine, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ivosidenib, Ixabepilone, Ketazolam, Lamivudine, Lamotrigine, Lansoprazole, Larotrectinib, Lasmiditan, Ledipasvir, Lefamulin, Lemborexant, Lenalidomide, Lenvatinib, Letermovir, Letrozole, Levamlodipine, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Loratadine, Losartan, Lurbinectedin, Lusutrombopag, Medrysone, Mefloquine, Meperidine, Methotrexate, Methylene blue, Methylprednisolone, Metoclopramide, Mibefradil, Mirabegron, Monensin, Morphine, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nitrofurantoin, Nizatidine, Nortriptyline, Octreotide, Odanacatib, Olanzapine, Olaparib, Olopatadine, Omadacycline, Ombitasvir, Omeprazole, Osimertinib, Oxcarbazepine, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Panobinostat, Pantoprazole, Paritaprevir, Pazopanib, Pemigatinib, Pentazocine, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Platelet Activating Factor, Pomalidomide, Ponatinib, Posaconazole, Pravastatin, Prazosin, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Progesterone, Propranolol, Prucalopride, Quetiapine, Quinidine, Quinine, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Remdesivir, Reserpine, Revefenacin, Rhodamine 6G, Rifamycin, Rimegepant, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Selpercatinib, Selumetinib, Sildenafil, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Talazoparib, Talinolol, Tamoxifen, Taurocholic acid, Tazemetostat, Technetium Tc-99m sestamibi, Tegaserod, Telaprevir, Temsirolimus, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Testosterone propionate, Tezacaftor, Ticagrelor, Timolol, Tipranavir, Tolvaptan, Topiramate, Topotecan, Toremifene, Trastuzumab deruxtecan, Trastuzumab emtansine, Trimethoprim, Trimipramine, Tucatinib, Ubidecarenone, Ubrogepant, Umeclidinium, Upadacitinib, Valinomycin, Vardenafil, Vecuronium, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vismodegib, Voxilaprevir, Zanubrutinib, Zidovudine
4P-glycoprotein 1 modulatorsAcetylsalicylic acid, Avapritinib, Prazosin
5P-glycoprotein 1 transportersLedipasvir, Tocopherol
6P-glycoprotein 1 bindersTechnetium Tc-99m tetrofosmin
7P-glycoprotein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Mitoxantrone is a P-glycoprotein 1 inhibitor
1P-glycoprotein 1 inducersAcetylsalicylic acid, Aldosterone, Amiodarone, Amprenavir, Apalutamide, Atazanavir, Beclomethasone dipropionate, Betamethasone phosphate, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Colchicine, Darunavir, Daunorubicin, Dexamethasone, Dexamethasone acetate, Diclofenac, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Hydrocortisone, Indinavir, Ivermectin, Levothyroxine, Liothyronine, Liotrix, Lopinavir, Lumacaftor, Methylprednisolone, Mifepristone, Nefazodone, Nelfinavir, Nifedipine, Phenobarbital, Platelet Activating Factor, Prednisolone phosphate, Prednisone, Progesterone, Propofol, Reserpine, Rifabutin, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Tipranavir, Trazodone, Vinblastine, Vincristine
2P-glycoprotein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Alectinib, Alfentanil, Alpelisib, Amiodarone, Amlodipine, Amodiaquine, Amsacrine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Axitinib, Azelastine, Azithromycin, Benzocaine, Bepridil, Bicalutamide, Biricodar, Bisoprolol, Boceprevir, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carfilzomib, Carvedilol, Caspofungin, Ceftriaxone, Cethromycin, Cetirizine, Chloroquine, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colforsin, Concanamycin A, Conivaptan, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dacomitinib, Dactinomycin, Darunavir, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexamethasone acetate, Dexniguldipine, Dexverapamil, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Dovitinib, Doxazosin, Doxorubicin, Dronabinol, Dronedarone, Duloxetine, Elacridar, Elagolix, Elbasvir, Elexacaftor, Emopamil, Enalapril, Enasidenib, Entrectinib, Enzalutamide, Erdafitinib, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Esomeprazole, Estramustine, Etoposide, Favipiravir, Fedratinib, Felodipine, Fentanyl, Fingolimod, Flibanserin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Galantamine, Gallopamil, Gefitinib, Genistein, Glasdegib, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Hydroxychloroquine, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Istradefylline, Itraconazole, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ketoconazole, Lamotrigine, Laniquidar, Lansoprazole, Lapatinib, Lasmiditan, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lonafarnib, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Lurbinectedin, Medroxyprogesterone acetate, Mefloquine, Megestrol acetate, Methadone, Methylene blue, Metronidazole, Mibefradil, Miconazole, Mifepristone, Mirabegron, Mitotane, Naproxen, Nefazodone, Nelfinavir, Neratinib, Netupitant, Nicardipine, Niguldipine, Nilotinib, Nintedanib, Nisoldipine, Nitrendipine, Norethisterone, Norgestimate, Olaparib, Omeprazole, ONT-093, Paclitaxel, Palbociclib, Paliperidone, Pantoprazole, Paroxetine, Pemigatinib, Pibrentasvir, Pimozide, Piperine, Polyethylene glycol, Polyethylene glycol 400, Ponatinib, Posaconazole, Prazosin, Primaquine, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rifamycin, Rilpivirine, Ripretinib, Ritonavir, Rolapitant, Rucaparib, Salinomycin, Saquinavir, Sarecycline, Scopolamine, Selegiline, Selpercatinib, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Tamoxifen, Tariquidar, Taurocholic acid, Telaprevir, Telmisartan, Temsirolimus, Tenofovir disoproxil, Terazosin, Terfenadine, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Tezacaftor, Ticagrelor, Tipifarnib, Tipranavir, Tolvaptan, Trifluoperazine, Triflupromazine, Troleandomycin, Upadacitinib, Valinomycin, Valspodar, Vandetanib, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine, Zonisamide, Zosuquidar
3P-glycoprotein 1 substratesAbemaciclib, Acebutolol, Acenocoumarol, Acetaminophen, Acetylsalicylic acid, Afatinib, Albendazole, Aldosterone, Alectinib, Aliskiren, Alitretinoin, alpha-Tocopherol acetate, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Apixaban, Apremilast, Arsenic trioxide, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Avatrombopag, Axitinib, Azathioprine, Azithromycin, Baricitinib, Beclomethasone dipropionate, Belantamab mafodotin, Belinostat, Betamethasone, Betamethasone phosphate, Betrixaban, Bisoprolol, Bortezomib, Bosutinib, Bromocriptine, Budesonide, Cabazitaxel, Cabergoline, Camptothecin, Canagliflozin, Capmatinib, Carfilzomib, Celecoxib, Ceritinib, Cerivastatin, Cethromycin, Cetirizine, Chloramphenicol succinate, Chloroquine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Daclatasvir, Dacomitinib, Dactinomycin, Dapagliflozin, Darolutamide, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquine, Dexamethasone, Dexamethasone acetate, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxepin, Doxorubicin, Duvelisib, Edoxaban, Elagolix, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Empagliflozin, Enasidenib, Enfortumab vedotin, Entrectinib, Epinastine, Erdafitinib, Erlotinib, Ertugliflozin, Erythromycin, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinylestradiol, Etoposide, Everolimus, Ezetimibe, Fedratinib, Fesoterodine, Fexofenadine, Fidaxomicin, Flecainide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fostemsavir, Gefitinib, Gemcitabine, Gilteritinib, Glasdegib, Glecaprevir, Gramicidin D, Grapiprant, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Hydroxyzine, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ivosidenib, Ixabepilone, Ketazolam, Lamivudine, Lamotrigine, Lansoprazole, Larotrectinib, Lasmiditan, Ledipasvir, Lefamulin, Lemborexant, Lenalidomide, Lenvatinib, Letermovir, Letrozole, Levamlodipine, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Loratadine, Losartan, Lurbinectedin, Lusutrombopag, Medrysone, Mefloquine, Meperidine, Methotrexate, Methylene blue, Methylprednisolone, Metoclopramide, Mibefradil, Mirabegron, Monensin, Morphine, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nitrofurantoin, Nizatidine, Nortriptyline, Octreotide, Odanacatib, Olanzapine, Olaparib, Olopatadine, Omadacycline, Ombitasvir, Omeprazole, Osimertinib, Oxcarbazepine, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Panobinostat, Pantoprazole, Paritaprevir, Pazopanib, Pemigatinib, Pentazocine, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Platelet Activating Factor, Pomalidomide, Ponatinib, Posaconazole, Pravastatin, Prazosin, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Progesterone, Propranolol, Prucalopride, Quetiapine, Quinidine, Quinine, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Remdesivir, Reserpine, Revefenacin, Rhodamine 6G, Rifamycin, Rimegepant, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Selpercatinib, Selumetinib, Sildenafil, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Talazoparib, Talinolol, Tamoxifen, Taurocholic acid, Tazemetostat, Technetium Tc-99m sestamibi, Tegaserod, Telaprevir, Temsirolimus, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Testosterone propionate, Tezacaftor, Ticagrelor, Timolol, Tipranavir, Tolvaptan, Topiramate, Topotecan, Toremifene, Trastuzumab deruxtecan, Trastuzumab emtansine, Trimethoprim, Trimipramine, Tucatinib, Ubidecarenone, Ubrogepant, Umeclidinium, Upadacitinib, Valinomycin, Vardenafil, Vecuronium, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vismodegib, Voxilaprevir, Zanubrutinib, Zidovudine
4P-glycoprotein 1 modulatorsAcetylsalicylic acid, Avapritinib, Prazosin
5P-glycoprotein 1 transportersLedipasvir, Tocopherol
6P-glycoprotein 1 bindersTechnetium Tc-99m tetrofosmin
7P-glycoprotein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Mitoxantrone is a P-glycoprotein 1 inducer
1P-glycoprotein 1 inducersAcetylsalicylic acid, Aldosterone, Amiodarone, Amprenavir, Apalutamide, Atazanavir, Beclomethasone dipropionate, Betamethasone phosphate, Carbamazepine, Cholic Acid, Cimetidine, Clotrimazole, Colchicine, Darunavir, Daunorubicin, Dexamethasone, Dexamethasone acetate, Diclofenac, Digoxin, Doxorubicin, Estriol, Estrone, Etravirine, Hydrocortisone, Indinavir, Ivermectin, Levothyroxine, Liothyronine, Liotrix, Lopinavir, Lumacaftor, Methylprednisolone, Mifepristone, Nefazodone, Nelfinavir, Nifedipine, Phenobarbital, Platelet Activating Factor, Prednisolone phosphate, Prednisone, Progesterone, Propofol, Reserpine, Rifabutin, Rifampicin, Ritonavir, Saquinavir, Sirolimus, Spironolactone, St. John's Wort, Streptozocin, Tacrolimus, Tamoxifen, Tesmilifene, Tipranavir, Trazodone, Vinblastine, Vincristine
2P-glycoprotein 1 inhibitorsAbemaciclib, Acetaminophen, Afatinib, Alectinib, Alfentanil, Alpelisib, Amiodarone, Amlodipine, Amodiaquine, Amsacrine, Astemizole, Asunaprevir, Atazanavir, Atorvastatin, Atovaquone, Axitinib, Azelastine, Azithromycin, Benzocaine, Bepridil, Bicalutamide, Biricodar, Bisoprolol, Boceprevir, Bromocriptine, Buprenorphine, Buspirone, Cabazitaxel, Canagliflozin, Candesartan, Candesartan cilexetil, Captopril, Carfilzomib, Carvedilol, Caspofungin, Ceftriaxone, Cethromycin, Cetirizine, Chloroquine, Chlorpromazine, Chlorprothixene, Cholesterol, Cilazapril, Citalopram, Clarithromycin, Clofazimine, Clomipramine, Clotrimazole, Cobicistat, Colforsin, Concanamycin A, Conivaptan, Crizotinib, Curcumin, Cyclosporine, Daclatasvir, Dacomitinib, Dactinomycin, Darunavir, Dasatinib, Daunorubicin, Desipramine, Desloratadine, Desmethylsertraline, Dexamethasone, Dexamethasone acetate, Dexniguldipine, Dexverapamil, Digoxin, Dihydroergotamine, Diltiazem, Dipyridamole, Dofequidar, Dovitinib, Doxazosin, Doxorubicin, Dronabinol, Dronedarone, Duloxetine, Elacridar, Elagolix, Elbasvir, Elexacaftor, Emopamil, Enalapril, Enasidenib, Entrectinib, Enzalutamide, Erdafitinib, Ergometrine, Ergotamine, Erlotinib, Erythromycin, Esomeprazole, Estramustine, Etoposide, Favipiravir, Fedratinib, Felodipine, Fentanyl, Fingolimod, Flibanserin, Fluconazole, Fluoxetine, Flupentixol, Fluphenazine, Flurazepam, Fluvoxamine, Galantamine, Gallopamil, Gefitinib, Genistein, Glasdegib, Glecaprevir, Glyburide, Gramicidin D, Grepafloxacin, Haloperidol, HM-30181, Hycanthone, Hydroxychloroquine, Idelalisib, Imatinib, Indinavir, Indomethacin, Isavuconazole, Isavuconazonium, Istradefylline, Itraconazole, Ivacaftor, Ivermectin, Ivosidenib, Ixabepilone, Ketoconazole, Lamotrigine, Laniquidar, Lansoprazole, Lapatinib, Lasmiditan, Letermovir, Levofloxacin, Lidocaine, Lomerizine, Lomitapide, Lonafarnib, Lopinavir, Loratadine, Losartan, Lovastatin, Lumacaftor, Lurbinectedin, Medroxyprogesterone acetate, Mefloquine, Megestrol acetate, Methadone, Methylene blue, Metronidazole, Mibefradil, Miconazole, Mifepristone, Mirabegron, Mitotane, Naproxen, Nefazodone, Nelfinavir, Neratinib, Netupitant, Nicardipine, Niguldipine, Nilotinib, Nintedanib, Nisoldipine, Nitrendipine, Norethisterone, Norgestimate, Olaparib, Omeprazole, ONT-093, Paclitaxel, Palbociclib, Paliperidone, Pantoprazole, Paroxetine, Pemigatinib, Pibrentasvir, Pimozide, Piperine, Polyethylene glycol, Polyethylene glycol 400, Ponatinib, Posaconazole, Prazosin, Primaquine, Progesterone, Promethazine, Propafenone, Protriptyline, Quercetin, Quinacrine, Quinidine, Quinine, Ranitidine, Ranolazine, Reboxetine, Regorafenib, Reserpine, Reversin 121, Rifamycin, Rilpivirine, Ripretinib, Ritonavir, Rolapitant, Rucaparib, Salinomycin, Saquinavir, Sarecycline, Scopolamine, Selegiline, Selpercatinib, Sertraline, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sorafenib, Staurosporine, Sunitinib, Tacrolimus, Tamoxifen, Tariquidar, Taurocholic acid, Telaprevir, Telmisartan, Temsirolimus, Tenofovir disoproxil, Terazosin, Terfenadine, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tetrandrine, Tezacaftor, Ticagrelor, Tipifarnib, Tipranavir, Tolvaptan, Trifluoperazine, Triflupromazine, Troleandomycin, Upadacitinib, Valinomycin, Valspodar, Vandetanib, Vardenafil, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Voacamine, Voxilaprevir, Zimelidine, Zonisamide, Zosuquidar
3P-glycoprotein 1 substratesAbemaciclib, Acebutolol, Acenocoumarol, Acetaminophen, Acetylsalicylic acid, Afatinib, Albendazole, Aldosterone, Alectinib, Aliskiren, Alitretinoin, alpha-Tocopherol acetate, Ambrisentan, Amitriptyline, Amlodipine, Amprenavir, Anastrozole, Apixaban, Apremilast, Arsenic trioxide, Artesunate, Asunaprevir, Atazanavir, Atorvastatin, Avatrombopag, Axitinib, Azathioprine, Azithromycin, Baricitinib, Beclomethasone dipropionate, Belantamab mafodotin, Belinostat, Betamethasone, Betamethasone phosphate, Betrixaban, Bisoprolol, Bortezomib, Bosutinib, Bromocriptine, Budesonide, Cabazitaxel, Cabergoline, Camptothecin, Canagliflozin, Capmatinib, Carfilzomib, Celecoxib, Ceritinib, Cerivastatin, Cethromycin, Cetirizine, Chloramphenicol succinate, Chloroquine, Chlorpromazine, Cimetidine, Ciprofloxacin, Cisplatin, Citalopram, Clarithromycin, Clindamycin, Clobazam, Clofazimine, Clomifene, Clonidine, Clopidogrel, Clozapine, Cobimetinib, Colchicine, Conjugated estrogens, Copanlisib, Crizotinib, Cyclosporine, Dabigatran etexilate, Dabrafenib, Daclatasvir, Dacomitinib, Dactinomycin, Dapagliflozin, Darolutamide, Dasabuvir, Dasatinib, Daunorubicin, Debrisoquine, Dexamethasone, Dexamethasone acetate, Diazepam, Diethylstilbestrol, Digitoxin, Digoxin, Diltiazem, Dipyridamole, Docetaxel, Dolutegravir, Domperidone, Doxepin, Doxorubicin, Duvelisib, Edoxaban, Elagolix, Elbasvir, Eletriptan, Elexacaftor, Eliglustat, Empagliflozin, Enasidenib, Enfortumab vedotin, Entrectinib, Epinastine, Erdafitinib, Erlotinib, Ertugliflozin, Erythromycin, Escitalopram, Esomeprazole, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estriol, Estrone, Ethinylestradiol, Etoposide, Everolimus, Ezetimibe, Fedratinib, Fesoterodine, Fexofenadine, Fidaxomicin, Flecainide, Fluticasone, Fluticasone furoate, Fluticasone propionate, Fostemsavir, Gefitinib, Gemcitabine, Gilteritinib, Glasdegib, Glecaprevir, Gramicidin D, Grapiprant, Grazoprevir, Grepafloxacin, Haloperidol, Hydrocortisone, Hydroxyzine, Ibuprofen, Idelalisib, Imatinib, Imipramine, Indacaterol, Indinavir, Indomethacin, Inotuzumab ozogamicin, Irinotecan, Ivermectin, Ivosidenib, Ixabepilone, Ketazolam, Lamivudine, Lamotrigine, Lansoprazole, Larotrectinib, Lasmiditan, Ledipasvir, Lefamulin, Lemborexant, Lenalidomide, Lenvatinib, Letermovir, Letrozole, Levamlodipine, Levetiracetam, Levofloxacin, Levomilnacipran, Linagliptin, Loperamide, Loratadine, Losartan, Lurbinectedin, Lusutrombopag, Medrysone, Mefloquine, Meperidine, Methotrexate, Methylene blue, Methylprednisolone, Metoclopramide, Mibefradil, Mirabegron, Monensin, Morphine, Mycophenolate mofetil, Nadolol, Naloxone, Nelfinavir, Nicardipine, Nifedipine, Nilotinib, Nintedanib, Nitrofurantoin, Nizatidine, Nortriptyline, Octreotide, Odanacatib, Olanzapine, Olaparib, Olopatadine, Omadacycline, Ombitasvir, Omeprazole, Osimertinib, Oxcarbazepine, Ozanimod, Paclitaxel, Palbociclib, Paliperidone, Panobinostat, Pantoprazole, Paritaprevir, Pazopanib, Pemigatinib, Pentazocine, Phenobarbital, Phenytoin, Pibrentasvir, Pitavastatin, Platelet Activating Factor, Pomalidomide, Ponatinib, Posaconazole, Pravastatin, Prazosin, Prednisolone, Prednisolone acetate, Prednisolone phosphate, Prednisone, Progesterone, Propranolol, Prucalopride, Quetiapine, Quinidine, Quinine, Raloxifene, Ranitidine, Ranolazine, Regorafenib, Remdesivir, Reserpine, Revefenacin, Rhodamine 6G, Rifamycin, Rimegepant, Ripretinib, Risdiplam, Risperidone, Ritonavir, Rivaroxaban, Romidepsin, Rucaparib, Saquinavir, Selexipag, Selpercatinib, Selumetinib, Sildenafil, Silodosin, Simeprevir, Sitagliptin, Sofosbuvir, Somatostatin, Sorafenib, Sparfloxacin, Sphingosine, Stanolone, Stanolone acetate, Sumatriptan, Tacrine, Tacrolimus, Talazoparib, Talinolol, Tamoxifen, Taurocholic acid, Tazemetostat, Technetium Tc-99m sestamibi, Tegaserod, Telaprevir, Temsirolimus, Tenofovir, Tenofovir alafenamide, Tenofovir disoproxil, Testosterone propionate, Tezacaftor, Ticagrelor, Timolol, Tipranavir, Tolvaptan, Topiramate, Topotecan, Toremifene, Trastuzumab deruxtecan, Trastuzumab emtansine, Trimethoprim, Trimipramine, Tucatinib, Ubidecarenone, Ubrogepant, Umeclidinium, Upadacitinib, Valinomycin, Vardenafil, Vecuronium, Velpatasvir, Vemurafenib, Venetoclax, Venlafaxine, Verapamil, Vinblastine, Vincristine, Vinflunine, Vismodegib, Voxilaprevir, Zanubrutinib, Zidovudine
4P-glycoprotein 1 modulatorsAcetylsalicylic acid, Avapritinib, Prazosin
5P-glycoprotein 1 transportersLedipasvir, Tocopherol
6P-glycoprotein 1 bindersTechnetium Tc-99m tetrofosmin
7P-glycoprotein 1 antagonistsTocofersolan
Interacting GroupInteracting Drugs
Mitoxantrone is a Multidrug resistance-associated protein 1 substrate
1Multidrug resistance-associated protein 1 inhibitorsAbiraterone, Amprenavir, Atazanavir, Cannabidiol, Clofazimine, Conjugated estrogens, Daunorubicin, Diclofenac, Doxorubicin, Etoposide, Fingolimod, Genistein, Glutathione, Glyburide, Ibuprofen, Idarubicin, Indinavir, Indomethacin, Ivermectin, Lamivudine, Medical Cannabis, Methotrexate, Mifepristone, Myricetin, Nabiximols, Naringenin, Ofloxacin, Paclitaxel, Probenecid, Progesterone, Quercetin, Rifampicin, Ritonavir, Sulfinpyrazone, Taurocholic acid, Vandetanib, Vemurafenib, Verapamil, Vinblastine, Vincristine
2Multidrug resistance-associated protein 1 inducersCholic Acid, Fingolimod, Phenobarbital, Quercetin, Ritonavir, Taurocholic acid, Vinblastine
3Multidrug resistance-associated protein 1 substratesAcemetacin, Aminohippuric acid, Atazanavir, Atorvastatin, Belantamab mafodotin, Dactinomycin, Daunorubicin, Docetaxel, Doxorubicin, Epirubicin, Etoposide, Fluorescein, Glutathione, Grepafloxacin, Irinotecan, Methotrexate, Prasterone, Rhodamine 6G, Saquinavir, Saxagliptin, Technetium Tc-99m sestamibi, Trastuzumab deruxtecan, Vemurafenib, Vinblastine, Vincristine, Zoledronic acid
Interacting GroupInteracting Drugs
Mitoxantrone is a Multidrug resistance-associated protein 1 inhibitor
1Multidrug resistance-associated protein 1 inhibitorsAbiraterone, Amprenavir, Atazanavir, Cannabidiol, Clofazimine, Conjugated estrogens, Daunorubicin, Diclofenac, Doxorubicin, Etoposide, Fingolimod, Genistein, Glutathione, Glyburide, Ibuprofen, Idarubicin, Indinavir, Indomethacin, Ivermectin, Lamivudine, Medical Cannabis, Methotrexate, Mifepristone, Myricetin, Nabiximols, Naringenin, Ofloxacin, Paclitaxel, Probenecid, Progesterone, Quercetin, Rifampicin, Ritonavir, Sulfinpyrazone, Taurocholic acid, Vandetanib, Vemurafenib, Verapamil, Vinblastine, Vincristine
2Multidrug resistance-associated protein 1 inducersCholic Acid, Fingolimod, Phenobarbital, Quercetin, Ritonavir, Taurocholic acid, Vinblastine
3Multidrug resistance-associated protein 1 substratesAcemetacin, Aminohippuric acid, Atazanavir, Atorvastatin, Belantamab mafodotin, Dactinomycin, Daunorubicin, Docetaxel, Doxorubicin, Epirubicin, Etoposide, Fluorescein, Glutathione, Grepafloxacin, Irinotecan, Methotrexate, Prasterone, Rhodamine 6G, Saquinavir, Saxagliptin, Technetium Tc-99m sestamibi, Trastuzumab deruxtecan, Vemurafenib, Vinblastine, Vincristine, Zoledronic acid
Interacting GroupInteracting Drugs
Mitoxantrone is a ATP-binding cassette sub-family G member 2 substrate
1ATP-binding cassette sub-family G member 2 substratesAbemaciclib, Afatinib, Allopurinol, Alpelisib, Alvocidib, Apixaban, Artesunate, Baricitinib, Brigatinib, Camptothecin, Carboplatin, Celecoxib, Cerivastatin, Cisplatin, Cladribine, Clofarabine, Conjugated estrogens, Copanlisib, Dabrafenib, Dacomitinib, Dactinomycin, Darolutamide, Dasatinib, Daunorubicin, Delafloxacin, Docetaxel, Dolutegravir, Donepezil, Doxorubicin, Duvelisib, Empagliflozin, Enasidenib, Ertugliflozin, Etoposide, Ezetimibe, Fimasartan, Fluorouracil, Folic acid, Fostemsavir, Gefitinib, Glasdegib, Glecaprevir, Glyburide, Idelalisib, Imatinib, Irinotecan, Ivermectin, Lamivudine, Larotrectinib, Leflunomide, Lenvatinib, Lusutrombopag, Methotrexate, Mycophenolate mofetil, Nifurtimox, Nilotinib, Nitrofurantoin, Ombitasvir, Osimertinib, Oxaliplatin, Ozanimod, Palbociclib, Pantoprazole, Pazopanib, Pemigatinib, Pibrentasvir, Pitavastatin, Ponatinib, Pralatrexate, Prasterone, Pravastatin, Prazosin, Raloxifene, Revefenacin, Riluzole, Rimegepant, Riociguat, Ripretinib, Risdiplam, Rivaroxaban, Rosuvastatin, Rucaparib, Selpercatinib, Selumetinib, Simeprevir, Sofosbuvir, Sorafenib, Sulfasalazine, Sumatriptan, Talazoparib, Tamoxifen, Tazemetostat, Tegaserod, Teniposide, Tenofovir alafenamide, Teriflunomide, Testosterone, Testosterone cypionate, Testosterone enanthate, Testosterone undecanoate, Tezacaftor, Topotecan, Trastuzumab deruxtecan, Tucatinib, Ubrogepant, Upadacitinib, Velpatasvir, Vemurafenib, Vincristine, Voxilaprevir, Zidovudine
2ATP-binding cassette sub-family G member 2 inhibitorsAbemaciclib, Afatinib, Alectinib, Avatrombopag, Baricitinib, Beclomethasone dipropionate, Brigatinib, Buprenorphine, Cabazitaxel, Caffeine, Cannabidiol, Capmatinib, Clofazimine, Cobicistat, Cyclosporine, Dabrafenib, Daclatasvir, Dacomitinib, Daidzin, Darolutamide, Dasabuvir, Dasatinib, Dexamethasone, Dexamethasone acetate, Diethylstilbestrol, Dovitinib, Dronabinol, Elacridar, Eltrombopag, Enasidenib, Erlotinib, Estradiol, Estradiol acetate, Estradiol benzoate, Estradiol cypionate, Estradiol dienanthate, Estradiol valerate, Estrone, Fedratinib, Fostamatinib, Fostemsavir, Fusidic acid, Gefitinib, Genistein, Gilteritinib, Glasdegib, Glecaprevir, Hesperetin, Imatinib, Isavuconazole, Istradefylline, Lansoprazole, Lasmiditan, Letermovir, Medical Cannabis, Nabiximols, Naringenin, Nelfinavir, Nilotinib, Novobiocin, Olaparib, Omeprazole, Palbociclib, Pantoprazole, Paritaprevir, Pibrentasvir, Ponatinib, Progesterone, Quercetin, Rabeprazole, Regorafenib, Rilpivirine, Ripretinib, Ritonavir, Rolapitant, Rucaparib, Safinamide, Saquinavir, Selpercatinib, Simeprevir, Sorafenib, Sulfasalazine, Sunitinib, Tafamidis, Taurocholic acid, Telmisartan, Teriflunomide, Topiroxostat, Upadacitinib, Vandetanib, Velpatasvir, Vemurafenib, Venetoclax, Vismodegib, Voxilaprevir
3ATP-binding cassette sub-family G member 2 inducersApalutamide, Cholesterol, Dovitinib, Progesterone, Venlafaxine
4ATP-binding cassette sub-family G member 2 antagonistsZafirlukast
5ATP-binding cassette sub-family G member 2 weak inhibitorsCobimetinib
6ATP-binding cassette sub-family G member 2 transportersLedipasvir
7ATP-binding cassette sub-family G member 2 modulatorsAvapritinib