| Gefitinib | A tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria. |
| Topotecan | An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer. |
| Glyburide | A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. |
| Pravastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke. |
| Doxorubicin | A medication used to treat various cancers and Kaposi's Sarcoma. |
| Mitoxantrone | A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis. |
| Sorafenib | A kinase inhibitor used in the treatment of unresectable liver carcinoma and advanced renal carcinoma. |
| Sulfasalazine | An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. |
| Dasatinib | A tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy. |
| Prazosin | An alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension. |
| Lamivudine | A reverse transcriptase inhibitor used to treat HIV and hepatitis B infections. |
| Irinotecan | An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum. |
| Etoposide | A podophyllotoxin derivative used to treat testicular and small cell lung tumors. |
| Dactinomycin | An actinomycin used to treat a wide variety of cancers. |
| Conjugated estrogens | A mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis. |
| Cerivastatin | A statin (or HMG CoA reductase inhibitor) used with dietary changes to decrease lipid levels and reduce the risk of cardiovascular events. |
| Testosterone | A hormone used to treat hypogonadism, breast carcinoma in women, or the vasomotor symptoms of menopause. |
| Tamoxifen | A selective estrogen receptor modulator used to treat estrogen receptor positive breast cancer, reduce the risk of invasive breast cancer following surgery, or reduce the risk of breast cancer in high risk women. |
| Daunorubicin | An anthracycline aminoglycoside used to induce remission of nonlymphocytic leukemia and acute lymphocytic leukemia. |
| Methotrexate | An antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis. |
| Folic acid | A nutrient used to treat megaloblastic anemia and is found in many supplements. |
| Alvocidib | Investigated for use/treatment in esophageal cancer, leukemia (lymphoid), lung cancer, liver cancer, and lymphoma (unspecified). |
| Teniposide | A cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia. |
| Nitrofurantoin | An antibiotic used to treat urinary tract infections. |
| Ivermectin | An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis. |
| Camptothecin | Investigated for the treatment of cancer. |
| Riluzole | A glutamate antagonist used to treat amyotrophic lateral sclerosis. |
| Cladribine | A purine antimetabolite used for the management of relapsing forms of Multiple Sclerosis (MS), used in patients who have not responded to or who were unable to tolerate alternative MS drugs. |
| Clofarabine | A purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old. |
| Oxaliplatin | A platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer. |
| Pitavastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Pazopanib | An antineoplastic agent used in the treatment of advanced renal cell cancer and advanced soft tissue sarcoma in patients with prior chemotherapy. |
| Teriflunomide | A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. |
| Leflunomide | A pyrimidine synthesis inhibitor indicated to treat rheumatoid arthritis. |
| Vemurafenib | A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. |
| Apixaban | An anticoagulant used for the prophylaxis of stroke and systemic embolism in nonvalvular atrial fibrillation, and deep vein thrombosis(DVT) leading to pulmonary embolism(PE), including in patients after a hip or knee replacement surgery. |
| Ponatinib | A kinase inhibitor used to treat patients with various types of chronic myeloid leukemia (CML). |
| Dabrafenib | A kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer. |
| Zidovudine | A dideoxynucleoside used in the treatment of HIV infection. |
| Afatinib | An antineoplastic agent used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) with non-resistant EGFR mutations or resistance to platinum-based chemotherapy. |
| Fluorouracil | A pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment. |
| Mycophenolate mofetil | An inosine monophosphate dehydrogenase inhibitor used to prevent the rejection of kidney, heart, or liver transplants. |
| Rosuvastatin | An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. |
| Sofosbuvir | A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents. |
| Lenvatinib | A receptor tyrosine kinase inhibitor used for the treatment of metastatic thyroid cancer, advanced renal cell carcinoma in combination with everolimus, and unresectable hepatocellular carcinoma. |
| Idelalisib | An antineoplastic kinase inhibitor used to treat chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). |
| Osimertinib | A tyrosine kinase inhibitor used in the treatment of certain types of non-small cell lung carcinoma. |
| Riociguat | A stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension. |
| Venetoclax | A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia. |
| Velpatasvir | A NS5A inhibitor used to treat chronic hepatitis C infections in patients without cirrhosis or with compensated cirrhosis. |
| Simeprevir | A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. |
| Ombitasvir | A direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections. |
| Delafloxacin | A fluoroquinolone antibiotic used to treat skin and skin structure infections. |
| Voxilaprevir | A nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections. |
| Enasidenib | An isocitrate dehydrogenase-2 inhibitor used to treat relapsed or refractory acute myeloid leukemia with an isocitrate dehydrogenase-2 mutation. |
| Pibrentasvir | A Hepatitis C NS5A inhibitor used to treat Hepatitis C. |
| Glecaprevir | A Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C. |
| Copanlisib | A medication used to treat relapsed follicular lymphoma who have attempted at least two other treatments. |
| Abemaciclib | A medication used to treat HR+ HER2- advanced or metastatic breast cancer. |
| Brigatinib | An anaplastic lymphoma kinase inhibitor used to treat anaplastic lymphoma kinase positive metastatic non small cell lung cancer. |
| Dolutegravir | An antiviral agent used for the treatment of HIV-1 infections in combination with other antiretroviral agents. |
| Rucaparib | An anti-cancer agent used to treat recurrent ovarian, fallopian tube, or peritoneal cancer. |
| Baricitinib | A Janus kinase inhibitor used to treat moderate to severe rheumatoid arthritis that has responded poorly to at least one TNF antagonist. |
| Ertugliflozin | A SGLT2 inhibitor used to treat type 2 diabetes mellitus. |
| Testosterone cypionate | An androgen used to treat low or absent testosterone. |
| Testosterone enanthate | An androgen used to treat low or absent testosterone. |
| Testosterone undecanoate | An androgen used to treat low or absent testosterone. |
| Imatinib | A tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors. |
| Nilotinib | A kinase inhibitor used for the chronic phase treatment of Chronic Myeloid Leukemia (CML) that is Philadelphia chromosome positive and for the treatment of CML that is resistant to therapy containing imatinib. |
| Ritonavir | An HIV protease inhibitor used in combination with other antivirals in the treatment of HIV infection. |
| Lusutrombopag | A medication used to treat thrombocytopenia in patients with chronic liver disease scheduled to have a procedure. |
| Duvelisib | An inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma. |
| Sumatriptan | A serotonin receptor agonist used to treat migraines and cluster headaches. |
| Vincristine | A vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. |
| Ezetimibe | A cholesterol absorption inhibitor used to lower total cholesterol, LDL-C, Apo-B, and non-HDL-C in primary hyperlipidemia and familial cholesterolemia. |
| Docetaxel | A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. |
| Talazoparib | A poly-ADP ribose polymerase inhibitor used to treat HER2-, BRCA mutated locally advanced or metastatic breast cancer. |
| Dacomitinib | A medication used to treat non small cell lung cancer with EGFR exon 19 deletion of exon 21 L858R substitution. |
| Larotrectinib | A kinase inhibitor used to treat solid tumors with neurotrophic receptor tyrosine kinase gene fusion, are metastatic, high risk for surgery, or have no alternative treatments. |
| Revefenacin | An anticholinergic agent used to treat COPD. |
| Rivaroxaban | A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations. |
| Fimasartan | Used for the treatment of hypertension and heart failure . |
| Glasdegib | A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy. |
| Pantoprazole | A proton pump inhibitor used to treat erosive esophagitis, gastric acid hypersecretion, and to promote healing of tissue damage caused by gastric acid. |
| Allopurinol | A xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. |
| Palbociclib | An endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer. |
| Tegaserod | A serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men. |
| Tenofovir alafenamide | A nucleoside analog reverse transcriptase inhibitor used for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease. |
| Raloxifene | A selective estrogen receptor modulator that is used to prevent and treat osteoporosis and reduce the risk of invasive breast cancer in high-risk postmenopausal women. |
| Alpelisib | Alpelisib is indicated in combination with fulvestrant to treat postmenopausal women, and men, with advanced or metastatic breast cancer.[Label] This cancer must be hormone receptor (HR)-positive, human epidermal growth factor... |
| Cisplatin | A platinum based chemotherapy agent used to treat various sarcomas, carcinomas, lymphomas, and germ cell tumors. |
| Carboplatin | A alkylating agent used to treat advanced ovarian cancer. |
| Celecoxib | An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. |
| Donepezil | An acetylcholinesterase inhibitor used to treat the behavioral and cognitive effects of Alzheimer's Disease and other types of dementia. |
| Trastuzumab deruxtecan | An antibody used to treat certain types of unresectable or metastatic HER-2 positive breast cancer. |
| Darolutamide | An androgen receptor antagonist used for castration-resistant, non-metastatic prostate cancer. |
| Upadacitinib | An oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis in adult patients who did not respond well to methotrexate. |
| Ubrogepant | An oral CGRP antagonist used in the acute treatment of migraine with or without aura. |
| Tazemetostat | A methyltransferase inhibitor indicated to treat patients 16 years and older with metastatic or locally advanced epithelioid sarcoma not eligible for complete resection. |
| Tezacaftor | A medication used to treat homozygous or heterozygous F508del mutation cystic fibrosis. |
| Rimegepant | An oral CGRP receptor antagonist used for the acute treatment of migraines with or without aura in adults. |
| Ozanimod | A sphingosine 1-phosphate receptor modulator being studied to treat Multiple Sclerosis (MS) and inflammatory bowel disease (IBD). |
| Prasterone | A steroid formulated as a vaginal insert indicated for the treatment of moderate to severe dyspareunia associated with menopausal vulvar and vaginal atrophy. |
| Selumetinib | A MEK 1/2 inhibitor used in pediatric patients to treat neurofibromatosis type 1 (NF1) accompanied by symptomatic, inoperable plexiform neurofibromas (PN). |
| Tucatinib | A kinase inhibitor used to treat certain types of unresectable/metastatic HER-2 positive breast cancer. |
| Pemigatinib | A kinase inhibitor used to treat locally advanced or metastatic, unresectable cholangiocarcinoma in previously treated adult patients. |
| Pralatrexate | An antineoplastic agent used for the treatment of relapsed or refractory peripheral T-cell lymphoma. |
| Selpercatinib | A RET receptor tyrosine kinase inhibitor for the treatment of RET-driven non-small cell lung cancer, medullary thyroid cancer, and thyroid cancer in appropriate patient populations. |
| Ripretinib | A kinase inhibitor used to treat advanced gastrointestinal stromal tumor (GIST). |
| Empagliflozin | An SGLT2 inhibitor used to manage type 2 diabetes mellitus. |
| Artesunate | Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. |
| Fostemsavir | An antiretroviral HIV-1 attachment inhibitor targeted against the gp120 subunit within the HIV-1 gp160 envelope glycoprotein. |
| Risdiplam | An oral mRNA splicing modifier used in the treatment of spinal muscular atrophy (SMA). |
| Nifurtimox | An antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection). |
| Pralsetinib | A RET receptor tyrosine kinase inhibitor for the treatment of metastatic RET-driven non-small cell lung cancer. |
| Berotralstat | An inhibitor of plasma kallikrein used for prophylaxis of angioedema attacks in patients with hereditary angioedema. |
| Opicapone | A catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor. |
| Vericiguat | A soluble guanylate cyclase stimulator used to reduce heart failure-related hospitalization and cardiovascular death in patients with chronic systolic heart failure. |
| Cabotegravir | An HIV-1 integrase inhibitor. |
| Trilaciclib | A CDK4 and CDK6 inhibitor to reduce the risk of chemotherapy induced myelosuppression. |
| Sulpiride | A selective D2 dopamine receptor antagonist indicated to treat chronic and acute schizophrenia. |